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Publications
Publications (56)
Background:
Hospitalizations and surgical procedures are unpleasant for both children and their parents. Therefore, postoperative pain assessments and management are less commonly performed in younger children than in adults.
Purpose:
To evaluate the effects of nonpharmacological interventions on postoperative pain and anxiety in children.
Meth...
Introduction:
This study compared the submental surface electromyography (sEMG) duration and amplitude during dry swallowing between irradiated head and neck cancer (HNC) survivors and age-matched normal individuals. Further, the relationship between submental and infrahyoid sEMG in the irradiated HNC group was explored.
Method:
Forty participan...
Surgery of a child is a stressful event for the parents and the family. Pain management is an important part of treatment among children undergoing surgical procedures. The aim of this study was to examine the parent satisfaction level related to child’s post-operative pain management. The study included 160 mothers of children aged 2-7 years under...
Background
Reproductive well-being is a crucial element of women’s health. Due to the asymptomatic nature of gynaecological morbidities, women rarely seek medical advice in the initial period leading to delayed diagnosis and poor prognosis of subsequent disease. The present study aimed to explore the cervical cytology and its associated risk factor...
Objective
To explore stressors and support system for families with a neonate admitted with a systemic infection.
Design
Qualitative study using in-depth interviews (IDIs), based on principles of grounded theory.
Setting
A busy level III neonatal unit of a tertiary care teaching hospital in coastal Karnataka, India, between May 2018 and January 2...
Total laryngectomy (TL) is the surgical treatment option for advanced stage of laryngeal cancer, involving the removal of larynx along with several muscles attached to it. Several anatomical changes occur following the surgery which will in turn affect the swallowing mechanism. The severing of the cricopharyngeus muscle, which is an important muscl...
Abstract
Background
Paediatric postoperative pain management has developed rapidly, however children have remained untreated for postoperative pain because of difficulty in pain assessment and lack of awareness about standardized pain assessment tools and management interventions.
Objectives: To evaluate the efficacy of nurse assisted distraction s...
Aims:
To investigate the impact of microRNA target SNPs (mirSNPs) and their interaction with miRNAs on important drug-metabolizing enzymes, transporters and target genes for prediction of clopidogrel drug response in cardiovascular disease individuals.
Main methods:
A prospective cross-sectional study was conducted on 292 individuals undergoing...
Background
The incidence of neonatal sepsis in India is the highest in the world. Evidence regarding its risk factors can guide clinical practice and prevention strategies.
Objective
To review, assess and synthesize the available literature from India on the risk factors of sepsis among neonates.
Methodology
A systematic review was conducted. We...
Completed PRISMA checklist for the study.
(DOC)
Sensitivity analysis.
(DOCX)
Protocol of the systematic review.
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Results from studies not included in meta-analysis.
(DOCX)
Definitions and diagnostic criteria in included studies.
(DOCX)
Risk factor profile of the included studies.
(DOCX)
Quality assessment of included studies.
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Forest plots illustrating subgroup analysis.
(DOCX)
Funnel plots illustrating publication bias assessment.
(DOCX)
Introduction: In India, HIV patients are at a high risk of developing hematological and dermatological adverse drug reactions (ADRs) leading to financial burden. Materials and Methods: A prospective observational study was conducted on hematological and dermatological ADRs in a South Indian teaching hospital from October 2011 to October 2012. The d...
Background:
Community-based health insurance (CBHI) has been one of the options of health financing in India for a large number of population from the informal sector constituting about 90% of the total population. The objective of this study was to find out what are the factors which have influenced the beneficiaries to enroll in the schemes and...
In the wake of limited knowledge on verbal fluency performance in typically developing children, the present study aims at investigating the semantic fluency performance of Malayalam speaking children across age, gender and tasks. Using a cross-sectional study design, semantic fluency performance (on food and vehicle fluency tasks) was investigated...
The document gives the information on contextualising the evidence from the review for
South Asia and in particular to Nepal. The most common programmes implemented in South Asian countries are Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) followed by cash transfer programmes. These programmes are proven to be effective for imple...
Introduction: Tracheo-oesophageal (TE) speech is one of the most commonly used alaryngeal voice restoration options for individuals who have undergone a total laryngectomy. Cepstral Peak Prominence (CPP) implies the overall voice quality objectively. Aim: To compare the CPP between Blom-Singer non-indwelling low pressure and classic indwelling voic...
The focus of the current study was to interrogate the predictive potential of laser‐induced autofluorescence (LIAF) by objectively assessing collagen synthesis in burn wound granulation tissues ex vivo. Prior grafting, granulation tissues (20 samples) following burn injury were collected from 17 subjects of age range 18‐ 60 years with patient/donor...
Background:
Neonatal systemic infections and their consequent impairments give rise to long-lasting health, economic and social effects on the neonate, the family and the nation. Considering the dearth of consolidated economic evidence in this important area, this systematic review aims to critically appraise and consolidate the evidence on econom...
Background:
Greatest challenges for clinician is to recognize risk factors for clinically significant drug interactions (CSDIs). There is a lack of awareness about CSDIs among healthcare professionals in India.
Objective:
To recognize all possible risk factors for drug-drug interactions (DDIs) and to identify clinically significant drug interact...
Objective
The present study aimed to adapt and validate the Singing Voice Handicap Index (SVHI) into Kannada language using standard procedures.
Study Design
This is a cross-sectional study.
Methods
The original English version of SVHI was translated into Kannada. It was administered on 106 Indian classical singers, of whom 22 complained of voice p...
Introduction
Yakshagana, a popular traditional folk art from Karnataka, India, includes singing and dancing. Yakshagana singer or Bhagavata plays an important role in singing and conducting the performance. The present study aims to assess the singing vocal health using Singing Voice Handicap Index-10 (SVHI-10) in these singers and to compare betwe...
Background
Randomised controlled trials (RCTs) are gold standard in assessing the effectiveness of a clinical intervention because of their high internal validity. However, the same does not hold true for interventions conducted at the population level like public health interventions. Well-designed RCTs are not easy to conduct at population level....
Objective
The attitude of Indian classical singers toward seeking vocal health care is a dimension yet to be explored. The current study was aimed to determine the attitudes of these singers toward seeking vocal health care and further understand the influence of age and gender.
Study design
Cross-sectional.
Method
A 10-item self-report questionn...
The study aimed to investigate professional quality of life as reported by audiologists and speech language pathologists (SLPs) working in India. Questionnaire-based cross-sectional e-mail survey design using the Professional Quality of Life scale (ProQOL) was carried out. The sample consisted of professionals registered under the Indian Speech and...
Introduction
The support provided and the decisions taken by mothers determine the success of Universal Newborn Hearing Screening (UNHS). Attempts at exploring the existing knowledge-attitude among mothers is crucial to create/modify the existing screening programs. The present study attempts to explore the knowledge and attitude toward infant hear...
Many researches prefer to categorize count variable as binary and do the analysis.By categorizing the count variables into binary variable,we are loosing the information. In this paper, we analyze the use of count regression models as compared to logistic regression analysis. We had considered a count data of adverse drug reactions and applied diff...
We aimed to compare the acoustic parameters of voice between Madhya Saptak/Sthayi (MS) and Taar Saptak/Sthayi (TS) in trained Indian classical singers and between males and females.
Sixty-five adult trained Indian classical singers were instructed to produce MS and TS; the acoustic parameters were analyzed with the Multidimensional Voice Program. D...
Introduction: K4b2 (COSMED Srl – Italy) is a portable device that is considered valid and reliable for measuring oxygen uptake (VO2) and carbon dioxide production (VCO2) under laboratory conditions.
Objectives: Evaluate the test-retest reliability of K4b2 during walking, stair climbing and descending stairs under free living conditions.
Methods: T...
Background and Objectives
Potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) gene have a key role in insulin secretion and is of substantial interest as a candidate gene for type 2 diabetes (T2D). The current work was performed to delineate the genetic influence of KCNJ11 polymorphisms on risk of T2D in South Indian population t...
Physical activity trends for a lower-middle income country like India suggest a gradual decline in work related physical activity and no concomitant increase in leisure time physical activity. Perceived health benefits of physical activity and intention to increase physical activity have been established as independent correlates of physical activi...
Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity and causality of ADRs to HAART in Indian HIV positiv...
There are no studies performed in India on the safety of highly active antiretroviral therapy (HAART) combinations which focus on the base-line CD4+ T-cell count. Further, no data on risk factors for Adverse drug reactions (ADRs) to HAART and there is a lack of data on CD4+ T-cell count recovery after HAART.
The aim of this study was to assess risk...
In this paper we investigate utility of conditional and marginal likelihood approach for estimat-ing inflation parameter form zero inflated Poisson regression. We consider a hospital based prospective study in which factors associated with number of adverse drug reactions is of interest. Further number of Adverse Drug Reactions (ADR) depends on len...
The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent...
Comparison of acoustic parameters of voice between normal and high pitch phonation in normal adults, and comparison between genders.
A total of 48 normal laryngeal speakers were considered for this study. The acoustic parameters were analyzed using the Multi-Dimensional Voice Program. Descriptive statistics were used for analysis of the acoustic pa...
To determine the effects of combined in-patient rehabilitation with a home-based program on function and quality of life.
Tertiary care, university teaching hospital, randomized controlled trial.
Thirty admitted patients with congestive heart failure with New York Heart Association class II -IV. A five step individualised phase-1 cardiac rehabilita...
In India, very few reports on the cost of adverse drug reactions (ADRs) are available. There is a need to study this aspect of health care in order to understand the economic burden imposed by ADRs. The aim of the current work was to study the costs associated with documented ADRs in a tertiary care teaching hospital. This study was conducted in me...
Background
The potential drug-drug interaction (pDDI) increases as thenumber of concomitant medications increases. Patientswith cardiovascular disorders are at higher risk for drugdruginteractions because of the types and number of drugsthey receive. While drug interactions are reported to becommon, there is no published report of the prevalence of...
Evidence-based therapies (EBTs) for the prevention of cardiovascular disease (CVD) are reportedly underutilized in older people. The primary purpose of this study was to evaluate the use of EBTs for the prevention of CVD events in older people and secondarily whether a Home Medicines Review (HMR) service by pharmacists' predicts the use of these me...
Background:
Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration.
Study design:
This randomized control trial included 82 women randomly assigned t...
Asthma is a prevalent disease among adults in India. This study aims to find prevalence and risk factors for asthma among Indian women aged 15 to 49 based on Indian National Family Health Survey-3.
Prevalence of asthma was reported per 1,000 women among individual- and household-level variables. Chi-square test was used as test of association. Odds...
When a preterm infant is hospitalized, parents experience stress. Support by neonatal nurses is essential to relieve stress. This study investigated the interrelationships among stress, coping and nursing support of parents of preterm infants and the level of stress among mothers and fathers was compared. Descriptive cross-sectional survey was cond...
In the recent years there is a large application of large sample tests in many scientific investigations. The commonly used large sample tests are Likelihood ratio tests, Wald and Score tests. Wald and Score tests make use of expected fisher information in computation of test statistic. In complex problems the expressions for fisher information can...