Vasiliy Alexandrovich Savinov

• Federal State Budget Scientific Institution “Federal Scientific Centre VIEV” (FSC VIEV)

In this paper, the team of authors presents the results of determining the lytic activity of bacteriophages in relation to salmonella isolates isolated by routine bacteriological methods using time-of-flight mass spectrometry from pigs from various regions of the Russian Federation from sectional and pathoanatomic materials. The sensitivity of 72 s...

Relevance. The problem of listeriosis infection continues to be relevant in epizootology and epidemiology. Resistance to eradication of Listeria spp. due to the ability of the bacterium to adapt and persist in various environments, as well as its intracellular location and weak intracellular diffusion of some antibiotics. Listeriosis refers to sapr...

The study of the outbreak of dermatophytosis among rabbits in a large rabbit farm is presented. The clinical manifestation of the skin disease was characterized by separate and confluent foci of skin lesions covered with gypsum-like crusts. The disease was observed in all ages, starting from 10 days of age. Within a few months, the total infestatio...

Mass skin lesions in sables Martes zibellina in Siberia have been known since the 18th century, but their etiology is still not well understood. The disease affects up to 62 % of hunted sables, causing damage to the skin and causing serious economic loss. One of the versions suggests the participation of microscopic fungi in the occurrence of this...

Infectious diseases of turkeys, in particular salmonellosis and colibacteriosis, are a serious problem and lead to significant economic losses. The damage is due to the high mortality of young animals, reduced egg production in breeding herds, deterioration of meat quality, costs of treatment, elimination of the disease and preventive measures. How...

The article covers a selection method of dermatophyte fungi on the basis of their sporulation and populational stability in order to derive a highly productive vaccine strains. Twenty wild strains of Microsporum canis from the collection of FSC VIEV RAS were primary studied, from which strain M. canis No. 5 was chosen for further selection. After t...

Relevance. A number of methods are used to diagnose dermatophytosis in the practice of doctors, but their effectiveness varies. The aim of the study was to compare different methods of clinical and laboratory diagnosis of dermatophytosis. Methods. 54 clinical hair samples taken from small pets were examined for the presence of dermatophytes. Diagno...

Five methods for diagnosing of animal dermatophytosis were comparatively examined. A total of 54 hair samples from pets suspected for dermatophytosis were studied. The diagnostic efficiency of Wood’s lamp testing was 62.5%, while the share of false positive results was 16.7%. The direct microscopy revealed 56.3% positive samples and 7.4% false posi...

Fungal culture represents the «gold standard» for diagnosing infections caused by dermatophytes. However, laboratories and trained mycological staff are required for culture diagnostics. It is desirable to introduce methods for point-of-care diagnosis of dermatophytosis, which would be effective and easy to use. The aim of the study was the approba...

Оригинальное название статьи (RU): "Криптококкоз – оппортунистический микоз растущей значимости". Обобщены современные данные по этиологии, патогенезу, распространенности криптококкоза у животных, а также рассмотрены методы диагностики и терапии. Заболевание, вызываемое грибами рода Cryptococcus, поражает респираторную и центральную нервную систему...

Dermatophytic fungi Nannizzia persicolor, Nannizzia fulva, Trichophyton benhamiae and Microsporum ferrugineum were isolated from pets (cats, dogs, guinea pig) in Moscow region. The species identification was confirmed by ITS sequencing. Their macro- and micromorphological characteristics were described in comparison with Microsporum canis, the most...

Three file snakes (Acrochordus granulatus) were delivered to the Moscow Zoo (Russia) from Jakarta (Indonesia). Shortly after arrival, multiple white blisters were detected on their bodies. All three snakes died within a month of arrival. On microscopy, arthrospores and mycelium were seen in exudate from the lesions. Ophidiomyces ophidiicola was iso...

The study describes optimization stages of Russian medium "DTM-Expert" for express detection of dermatophytic fungi. In order to improve the growth promotion and indicative properties of the medium, several variations of nutritive compounds were studied. The medium containing mannitol and glucose as carbon sources showed the best indicative and gro...

Proceedings of Federal Scientific Centre VIEV. Vol. 82.

The aim of the study was to detect potentially pathogenic fungi in skin lesions of wild sables (Martes zibellina) from the Siberia region of Russia. Outbreaks of mass skin lesions in Siberian sables are known for decades, but their true etiology is still unknown. To reveal the possible etiological role of fungi, 15 samples from affected skins were...

The analysis of fatty acids composition and variability in anthropophilic and zoophilic strains of Microsporum canis is performed.

The need to reduce excessive, and often not rational, use of antibiotics in bacteriosis treatment and prevention is acknowledged unanimously by representatives of medicine and veterinary medicine. One of the most important tasks for relevant research and productive organizations is finding the alternative treatments for bacterial infections in view...

In the current one-year study 2477 samples from pets clinically suspected for dermatophytosis (1010 from dogs and 1467 from cats) were examined by direct microscopy, conventional mycological culture and DTM culture. Direct microscopy revealed 1,28% positive samples, conventional culture – 8,0% and DTM culture – 27,7% positive samples. The average i...

The paper presents an overview of atrophic rhinitis, a common and widely spread infectious disease caused by Bordetella bronchiseptica. The main virulence factors of the pathogen are cell wall lipopolysaccharides, fimbriae, toxins, microcapsules, pertactin - like proteins. B. Bronchiseptica also produces tracheal cytotoxin, dermonecrotic toxin, ade...

Dermatophytosis (ringworm) is the most important infectious and contagious skin disease of cats in shelters. Wherein, the diagnosis, identification and treatment of dermatophytosis is not always effective. Here we report an epidemiological study of the outbreak of feline dermatophytosis in animal shelter in Moscow region. At least 11% of cats kept...

The aim of the study was to develop a differential diagnostic medium for the rapid detection of animal dermatophytosis. For these purposes, tools such as Dermatophyte Test Medium (DTM) are successfully used abroad, but in our Russia such diagnostics have not been developed. As a result of the research, domestic "DTM-Expert" medium was elaborated an...

The results of microbiological screening of various organs and tissues obtained from wild migratory birds (ducks) in order to detect the presence of Riemerella anatipestifer, as well as study the total microbial biocenosis, are presented in the work. During the research, 90 species of cultivated bacteria were identified as part of the biocenosis of...

Elaboration of new diagnostic medium DTM-Expert for in-officce diagnosis of dermatophytosis.

The aim of the study was to develop a differential diagnostic nutrient medium for the rapid diagnosis of animal dermatophytosis. The commercial Dermatophyte Test Medium (DTM) is successfully used in many countries, but in Russia such diagnostics has not been developed yet. As a result of our research, we determined the optimal composition of the me...

Mycotoxins and mycotoxicoses represent an actual problem for various fields of agriculture – cattle breeding, pig breeding, poultry farming, fish farming. Mycotoxins (MT) cause harm to the health of animals and enormous economic damage, products of animal husbandry contaminated with mycotoxins can pose a threat to human health. This problem is impo...