Vasiliki Tsikourkitoudi

Karolinska Institutet | KI · Department of Microbiology, Tumor and Cell Biology (MTC)

During the last decade, inorganic nanoparticles have shown their therapeutic potential against infectious diseases, particularly in the fight against antimicrobial resistance. Inorganic nanomaterials may effectively address the drawbacks of conventional therapies since they possess optimized physicochemical properties in comparison to their bulk co...

We designed high-volumetric-energy-density supercapacitors from monolithic composites composed of self-standing carbon foam (CF) as the conducting matrix and embedded hierarchically organized porous carbon (PICK) as the active material. Using multiprobe scanning tunneling microscopy at selected areas, we were able to disentangle morphology-dependen...

Cholesterol‐dependent cytolysins (CDCs) are essential virulence factors for many human pathogens like Streptococcus pneumoniae (pneumolysin, PLY), Streptococcus pyogenes (streptolysin O, SLO), and Listeria monocytogenes (Listeriolysin, LLO) and induce cytolysis and inflammation. Recently, we identified that pneumococcal PLY interacts with the manno...

Nanoparticles exhibit potential as drug carriers in biomedicine due to their high surface-to-volume ratio that allows for facile drug loading. Nanosized drug delivery systems have been proposed for the delivery of biologics facilitating their transport across epithelial layers and maintaining their stability against proteolytic degradation. Here, w...

The controlled dissolution kinetics of iron‐doped copper oxide nanoparticles are applied in targeted nanomedicine. In their Research Article (DOI: 10.1002/anie.201912312), L. Mädler, S. J. Soenen et al. present a model‐based approach for adjusting the dissolution kinetics and intracellular release of copper that opens a therapeutic window for cance...

Die kontrollierte Auflösungskinetik Eisen‐dotierter Kupferoxid‐Nanopartikel wird in der gezielten Nanomedizin eingesetzt. In ihrem Forschungsartikel (DOI: 10.1002/ange.201912312) stellen L. Mädler, S. J. Soenen et al. einen Modell‐basierten Ansatz zur Anpassung der Auflösungskinetik und interzellulären Freigabe von Kupfer vor, der neue Krebstherapi...

The progress in nanomedicine (NM) using nanoparticles (NPs) is mainly based on drug carriers for the delivery of classical chemotherapeutics. While low NM delivery rates limit therapeutic efficacy, an entirely different approach was investigated. A homologous series of engineered CuO NPs was designed for dual purpose (carrier and drug) with a direc...

The progress in nanomedicine (NM) using nanoparticles (NPs) is mainly based on drug carriers for the delivery of classical chemotherapeutics. While low NM delivery rates limit therapeutic efficacy, an entirely different approach was investigated. A homologous series of engineered CuO NPs was designed for dual purpose (carrier and drug) with a direc...

With the exception of a limited number of sites in the body, primary tumors infrequently lead to the demise of cancer patients. Instead, mortality and a significant degree of morbidity result from the growth of secondary tumors in distant organs. Tumor survival, growth and dissemination are associated with the formation of both new blood vessels (a...

Purpose – The purpose of this paper is to produce cobalt (Co)-based thin films by metalorganic chemical vapor deposition (CVD) technique and then to evaluate structural and mechanical integrity. Design/methodology/approach – Co-based thin films were produced by metalorganic CVD technique. Boronizing, carburization and nitridation of the produced C...

H and E values are in good agreement with similar measurements in the literature.•Co3O4 thin film exhibits higher resistance to wear in comparison to the Co thin film.•Lower coefficient of friction for the Co3O4 thin film compared to the Co thin film was found.•Deformation of the films is mainly plastic all over the scratch path.

The scope of the present work is to present a modified model extracted by finite element method (FEM) analysis for the nanoindentation of polydimethylsiloxane (PDMS). The suggested model, based on Sneddon’s equation, takes into account the specimen finite dimensions and the indenter curvature. Load–displacement curves from FEM analysis are obtained...

In the present study, the nanoindentation creep behaviour of untreated and ultraviolet (UV) treated polydimethylsiloxane (PDMS) samples was investigated, accompanied with adhesion analysis and Fourier transform infrared spectroscopy (FTIR) characterisation. Different hold times, in the range of 5-2000 s (at 10 mu N of applied load), were incorporat...

Export Date: 20 November 2012, Source: Scopus, Language of Original Document: English, Correspondence Address: Charitidis, C.A.; National Technical University of Athens, School of Chemical Engineering, 9 Heroon Polytechniou Str., Zografos, Athens, GR-157 80, Greece; email: charitidis@chemeng.ntua.gr, References: Aboelfotoh, M.O., Marwick, A.D., Fre...

The adhesion and mechanical stability of thin film coatings on substrates is increasingly becoming a key issue in device reliability as magnetic and storage technology driven products demand smaller, thinner and more complex functional coatings. In the present study, chemical vapor deposited Co and Co 3O 4 thin films on SiO2 and Si substrates are p...

The adhesion and mechanical stability of thin film coatings on substrates is increasingly becoming a key issue in device reliability as magnetic and storage technology driven products demand smaller, thinner and more complex functional coatings. In the present study, chemical vapor deposited Co and Co3O4 thin films on SiO2 and Si substrates are pro...

Cited By (since 1996): 2, Export Date: 20 November 2012, Source: Scopus, Language of Original Document: English, Correspondence Address: Charitidis, C. A.; School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St, Zographos, Athens GR- 157 80, Greece; email: charitidis@chemeng.ntua.gr, References: Silva, M.N...