Vanya Gerasimova

• PhD
• Assistant Professor at Bulgarian Academy of Sciences

Recently, previously known viruses have changed their pathogenicity and encompassed new types of host populations. An example of such an infection is that caused by SARS-CoV, belonging to the “well-known” coronavirus family. Another group of viruses that are of great importance to the human population are the herpes viruses. Due to increasing viral...

Stephania dielsiana Y. C. Wu is a traditional medicinal plant that, like the other species of the genus Stephania , is used in some Asian countries for the treatment of various conditions and diseases. Phytochemical studies have revealed that the species’ therapeutic activity is mainly due to isoquinoline alkaloids. This study focused on the biolog...

Cannabis Sativa L., Cannabis Indica and Cannabis Hybrid are widespread plant species that find legal use in many countries around the world. The first of them has found considerable application in medicine, cosmetics, building construction, textile and food industries. Cannabis Indica and Cannabis Hybrid are used as raw materials for the extraction...

The root extracts of Stephania dielsiana Y.C.Wu (family Menispermaceae) are traditionally used for treatment of toothache, neuralgia and stomachache in Southeast Asian countries. The biological activity of the medicinal plant is associated with the presence of the pharmacologically active isoquinoline alkaloids. In order to assess the quality and t...

Datura stramonium L. is widespread in Europe and is one of the richest species of the tropane alkaloids. These alkaloids, especially atropine and scopolamine, are widely used in medicine for their antispasmodic, anticholinergic, and sedative properties. In addition, scopolamine is included in the World Health Organization’s list of essential medici...

Дисертационният труд представлява обемно и подробно проведено изследване, което включва, освен оценка на влиянието на основните екстракционни параметри върху добива на фенолни съединения от диворастящите, нетрадиционни за България, растителни видове - Cistus incanus L. (памуклийка), Trachystemon orientalis L. (източен лопох) и Phyllirea latifolia L...

Подходи и практики при валидиране на методи за количествен анализ на биологичноактивни вещества чрез високоефективна-течна хроматография 2023 г. Институт по Органична Химия с Център по Фитохимия, БАН

Phillyrea latifolia L. have played a very interesting role in the well-known historical medicine of the Mediterranean region. The wild shrub is widely distributed in Strandja mountain, Bulgaria where the ethno medicinal description of "Grypa" (local name) as an anti-inflammatory and antioxidant herb is missing. The purpose of the present study was...

In recent years, the interest in antioxidants in grape by-products has increased significantly as scientific research for the extraction and quantification of these compounds. In the present investigation was optimized the antioxidant yield of the grape pomace and seeds discharged as waste from the Bulgarian Mavrud winery, near to Trakiets village....

Ethnobotanical reports claim that St. John's Wort has important biological and chemical properties and can be used for the treatment of many diseases. Most studies related to Hypericum perforatum are focused on its antidepressant effects, but it has also been examined for wound healing, antiviral and antimicrobial activity. Hypericum perforatum con...

Il est connu que les plantes médicinales largement utilisées par les médecines alternatives pour prévenir les maladies résultant du stress oxydatif. Le but de la étude présenté était d'établir les profils phénoliques individuels des extraits de feuilles et de tiges de Melissa officinalis L. (lemon balm) et de Trachystemon orientalis L. ("Eastern Lo...

In the "Eastern Lopuh" from Strandja mountain, Bulgaria were found rutin (56.46 μg/mL) and myricetin (30.23 μg/mL). ✓ In the lemon balm infusion from NorthEastern Bulgaria were found polyphenols named gallic acid (56.20 μg/mL), epigallocatechin (188.99 μg/mL), quercetin (58.16 μg/mL), and kaempferol (0.67 μg/mL). For the analyses was developed a si...

The quantity and composition of phenolic compounds and anthocyanins differ according to the species, variety, maturity of the grapes, weather, viticultural practices, and the region where the grapes are grown. In the present investigation was evaluated the antioxidant yield from pressed crushed grapes. The samples were provided from the rose Mavrud...

The consumption of herbal infusions has increased in the last years because of plants, health benefits. The aim of the study was comparison of the polyphenol profiles of infusions prepared from Cistus incanus leaves collected from Bulgaria (Strandja mountain) and Greece (Khalkidhiki, Orange beach) using HPLC. For the analyses was developed a simple...

Remerciements: Ce travail a été soutenu par FRS-contrat de recherche № ДН 07/12 La Bulgarie a un long passé vinicole et est l'un des plus vieux pays producteur de vin au monde. Les déchets solides produits après la vinification pourraient représenter plus de 30% (w/w) des raisins utilisés. Les pomaces de raisins rouges, qui comprennent la peau et l...

Proving the popular and ethno medical descriptions of the utilization of Phillyrea green parts as anti-inflammatory remedy. • Representation an interesting perspective for Bulgaria and particular Strandja region such a high antioxidant wild plant regardless of the season of harvest. • A possible isolation and characterization of active compounds wi...

Evaluation of the effect of the temperature by the yield of polyphenols from dried leaves of the wild plant. • Trachystemon orientalis L. from Strandja, Bulgaria is a wild plant with a high content of polyphenols which yield increase with the increasing of the temperature of extraction. • Our results prove that the wild eastern borage can be used n...

Remerciements: Ce travail a été soutenu par FRS-contrat de recherche № ДН 07/12 • During vinification, only 30-40% of phenolic compounds are extracted, depending on grape varieties, vineyard location and technological parameters of winemaking (de-stemming, crushing, maceration, and pressing).• The quantity and composition of phenolic compounds and...

Grape pomace, an abundant by-product from the wine industry, is released in large quantities but remains unused. This investigation is focused on the optimization of extraction from grape pomace and grape seeds discharged as wastes from the Bulgarian Mavrud winery. The optimized parameters refer to the solid to the solvent ratio effect (1/10 g mL-1...

The purpose of the present study is to survey the extraction conditions and explore the antioxidant potential of the wild herb Cistus incanus, which is non-traditional in Bulgarian ethnomedicine and widespread in the Strandja Mountain. The influence of the extraction time (0–500 min) and solvent composition (0–50% ethanol in water) on the polypheno...

The purpose of the present study is survey of extraction conditions and exploring antioxidant potential of the non-traditional for the Bulgarian ethno-medicine wild herb Cistus incanus widespread in Strandja Mountain. The influence of the extraction time (0–500 min) and solvent composition (0–50% ethanol in water) on the polyphenols, flavonoids yie...

The purpose of the present study is survey of extraction conditions and exploring antioxidant potential of the non-traditional for the Bulgarian ethno-medicine wild herb Cistus incanus widespread in Strandja Mountain. The influence of the extraction time (0–500 min) and solvent composition (0–50% ethanol in water) on the polyphenols, flavanoids yie...

Present study investigates the effect of storage (at room temperature and at a frozen state) of Cistus incanus leaves and its hard-coated seeds on the total polyphenol content and the antioxidant capacity in view of the extraction carried out in 50 % ethanol-in water solution. A correlation between the polyphenol content and the antioxidant activit...