
Valeria RamírezUniversity of the Andes, Chile | UANDES · Faculty of Dentistry
Valeria Ramírez
Master in Public Health
About
52
Publications
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Introduction
https://orcid.org/0000-0003-2748-4351
- Magíster en Salud Pública Universidad de Chile.
- Profesor asociado categoría ordinaria Facultad de Odontología - Universidad de los Andes (CHILE).
- Docente Magíster Uandes en Investigación e Innovación en Ciencias de la Odontología.
- Docente Pregrado de Bioestadística - Facultad de Odontología- Universidad de los Andes (CHILE).
- Docente Bioestadística y epidemiología programa de postítulo de Ortodoncia.
Skills and Expertise
Additional affiliations
October 2008 - present
Education
March 2006 - December 2007
Escuela de Salud Pública
Field of study
- Public Health and Epidemiology
March 1993 - November 1998
Publications
Publications (52)
Aim
To characterize the gingival crevicular fluid (GCF) and plasma extracellular vesicles (EVs) and explore their proteomic cargo in healthy pregnant women compared to those with gestational diabetes mellitus (GDM) and periodontitis.
Methods
One‐hundred and four pregnant women were recruited at 24–30 gestation weeks. GDM was diagnosed by an oral g...
Objectives
Longitudinal assessment of the role of specific proteins on radiotherapy caries (RC) onset in head and neck cancer patients(HNC) up to one-year post-IMRT using a 5000ppm fluoride paste daily.
Materials and methods
Dental status/salivary protein data were obtained from 40 HNC patients pre-IMRT, six months (T1) and 12 months (T2) post-IMR...
Objective
Longitudinal assessment of the role of specific proteins on radiotherapy caries (RC) onset in head and neck cancer patients (HNC)up to one-year post intensity-modulated radiation therapy (IMRT).
Methods
Dental status/salivary protein data were obtained from 40 HNC patients pre-IMRT (T0), six months (T1) and 12 months (T2) post-IMRT (ethic...
Objective: To evaluate the relationship between oral health status, self-perception of oral health, and depression.
Methods: This cross-sectional study included 2953 individuals that were ≥ 18 years of age and participated in the Chilean National Health Survey (NHS), 2016–2017. Information on oral, dental, and mental health, and the presence or ab...
Objectives
To evaluate the relationship between obesity and periodontitis staging compared with periodontal healthy or gingivitis in pregnant women.
Materials and methods
An analytical cross-sectional study was conducted on pregnant women between 11 and 14 weeks of pregnancy. Sociodemographic, clinical, obstetric, and periodontal variables were st...
The objective of this study was to explore the relationship between intrinsic and extrinsic factors and a high cumulative score of the Basic Erosive Wear Examination (BEWE) in a Chilean adult group. A cross-sectional study was performed with the Ethics Committee’s approval from the Universidad de los Andes. A consecutive adult (18 to 46 years old)...
The objective of this study was to describe clinical and imaging changes of non-invasive therapies applied to patients with degenerative bone disorders of the temporomandibular joints (TMJ). To carry out this study, 25 patients with degenerative bone disorders of TMJ without previous treatment at the time of diagnosis, were evaluated. Non-invasive...
Early and innovative diagnostic strategies are required to predict the risk of developing pre-eclampsia (PE). The purpose of this study was to evaluate the performance of gingival crevicular fluid (GCF) placental alkaline phosphatase (PLAP) concentrations to correctly classify women at risk of PE. A prospectively collected, retrospectively stratifi...
Background:
To explore the diagnostic usefulness of extracellular vesicles (EVs), and their subpopulations (micro-vesicles and exosomes), and microRNAs (miRNA-21-3p, miRNA-150-5p, and miRNA-26a-5p) in peri-implant crevicular fluid (PICF) of subjects with healthy, peri-implant mucositis and peri-implantitis implants.
Methods:
A total of 54 patien...
Background
Suicide is a public health problem. The highest rates occur in men of 45-60 years old, and the most common methods are hanging, ingestion of pesticides, and firearms. Self-harm with or without suicide intention is the most critical factor identified for prevention, and it requires health care services. In Chile, the central-south regions...
Background:
Gestational diabetes mellitus (GDM) is increasing worldwide and women with a history of GDM are at risk of developing type 2 diabetes which is a risk factor for periodontitis.
Aim:
To explore the association between the concentrations of matrix metalloproteinase (MMP)-8 and -9 in gingival crevicular fluid (GCF) during early pregnancy...
Introduction
Our aim was to analyze the correlation between growth status in height and chronological age, carpal maturation, cervical maturation, and dental maturation, and assess the diagnostic performance of Demirjian's dental maturation as an indicator of the pubertal growth spurt, through a retrospective longitudinal study.
Methods
Records of...
Aim
To explore a set of inflammatory biomarkers obtained from dentinal fluid (DF) from patients with symptomatic irreversible pulpitis (IP), reversible pulpitis (RP) and normal pulp (NP).
Methodology
A cross‐sectional exploratory study was performed, recruiting 64 patients on the basis of their respective pulp condition. DF samples were obtained f...
Objective
To characterize extracellular vesicles (EVs) in gingival crevicular fluid (GCF) and saliva samples from healthy/gingivitis and periodontitis patients and correlate them with clinical inflammatory periodontal parameters.
Material and Method
An exploratory study, including 86 subjects was conducted. Clinical and periodontal data were recor...
A randomized controlled phase I/II clinical trial was designed to evaluate the safety and efficacy of encapsulated human umbilical cord mesenchymal stem cells in a plasma-derived biomaterial for regenerative endodontic procedures (REPs) in mature permanent teeth with apical lesions. The trial included 36 patients with mature incisors, canines, or m...
This paper explains how to screen tooth wear in general practice using the Basic Erosive Wear Examination (BEWE) index. It explains how stakeholders in the UK acknowledged the convenience of the BEWE and that it could be recorded at the same time as the Basic Periodontal Examination (BPE). The article contains examples of anterior and posterior too...
Objectives:
To determine the prevalence, severity and distribution of erosive tooth wear lesions in adult patients at the Universidad de los Andes Health Center in the San Bernardo Metropolitan Region, Chile, during a period of 4 months in 2016.
Methods:
A cross-sectional study was conducted. A consecutive sample of patients from 18 to 46 years...
The objective: was to determine the current contents of cariology taught, its clinical application and educational methodology used in Chilean undergraduate dental schools. Materials and Method: A cross-sectional study was carried out in a convenience sample of cariology teachers and/or teachers of cariology-related subjects belonging to 23 of the...
RESUMEN:
Objetivo:
Creación de un currículo de competencias mínimas en Cariología, para la formación de los Cirujano-Dentistas egresados de las escuelas de Odontología de Chile.
Metodologías:
A partir de una reunión de académicos de las Universidades de Talca y de Chile (año 2011), se elaboró una propuesta de currículo inicial, basado en los do...
Statement of problem:
Therapeutic procedures that increase occlusal vertical dimension (OVD) may have different responses in patients with different craniofacial vertical patterns. The effect on these patients of increasing their OVD is not well understood.
Purpose:
The purpose of this clinical study was to compare measurements of vertical jaw s...
Objetivo:
Creación de un currículo de competencias mínimas en Cariología, para la formación de los Cirujano-Dentistas egresados de las escuelas de Odontología de Chile.
Metodologías:
A partir de una reunión de académicos de las Universidades de Talca y de Chile (año 2011), se elaboró una propuesta de currículo inicial, basado en los dominios propu...
Aim:
To systematically asses, the definitions of aggressive periodontitis reported in original periodontal research.
Methods:
A systematic review of original research on aggressive periodontitis published in English.
Results:
The electronic search yielded 833 abstracts. Of these, 472 publications fulfilled the inclusion criteria and were appra...
Objectives:
To evaluate the effect of the application of photobiomodulation in a 2-year follow-up period in patients who have been intervened with a sagittal ramus split osteotomy and present neurosensory disturbance of the inferior alveolar nerve.
Background:
Photobiomodulation is a common clinical tool in dentistry, for its beneficial effects...
Introduction:
Direct pulp capping treatment is intended to preserve pulp vitality, to avoid or retard root canal treatment, and, in cases with an open apex, to allow continued root development. Historically, calcium hydroxide (CH) was the gold standard material, but nowadays calcium silicate materials (CSMs) are displacing CH because of their high...
Objective:
To describe mandibular premolar root and canal morphology and its variability in Chilean and Belgian samples using cone-beam computed tomography.
Methods:
A cross-sectional and descriptive study was conducted. A total of 402 mandibular premolars were examined using cone-beam computed tomography images of Chilean and Belgian patients....
Reports indicate that statins (cholesterol-lowering drugs), in addition to lowering cholesterol, have an immunomodulatory effect. This effect may be beneficial for the treatment of several diseases, including periodontal disease. The aim of the present study was to evaluate the immunomodulatory effect of an atorvastatin-medicated dentifrice on CD4+...
Describe the frequency of acneiform eruptions and / or exacerbations of a previous acne after orthognathic surgery. The sample consisted of 57 patients (n = 57) of both genders, undergoing orthognathic surgery, who were evaluated with a follow-up of 2 postoperative months, at different stages of surgery; Preoperative (0-7 days), immediate postopera...
Background
The aim of this study was to explore dental maturation as a diagnostic test for skeletal maturation.
Materials and Methods
Six hundred and fifty-seven growing individuals were classified according to their cervical vertebral maturity and dental maturity, both determined in lateral cephalograms and panoramic radiographs, respectively. Th...
Objective(s):
to explore the feasibility of measuring endothelial and placental biomarkers in saliva and gingival crevicular fluid (GCF), and to determine if patients with PE have a different profile of these biomarkers in oral fluids. Method A case-control study was conducted, including patients with PE (n = 10) and a control group with normal pr...
Background:
Despite the many studies trying to evaluate the magnitude of suicide in Chile, none of them include the new valid data, recently published by the DEIS of the Chilean Health Ministry.
Aim:
This paper sought to describe how suicide rates changed among Chileans who were at least 15 years of age during the period of 2001-2010; these rate...
Among oral pathologies, dental caries is the one that is easy to prevent with dental hygiene measures. Since the 1990's, oral health education has aimed at instilling the habit of tooth brushing twice a day with fluoride toothpaste to prevent this disease. However, there is a need to understand the effect of the context on the expected outcomes. Ob...
The study of predictors of academic performance is of great importance in the area of health. The objective of this study was to assess the relationship between PSU (University selection admission scores) and Secondary Education (High school grade point average score) in the freshmen morphology course in dentistry, at the Universidad de los Andes....
Objective To describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist. Material and methods A descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of Dávila Clinic. A group of them began statin therapy. Clinical...
There are several types of oral and pharyngeal cancer, with the most frequent being squamous cell carcinoma (90%). It is more common in men, in adulthood. It is associated with multiple risk factors, mainly smoking and alcohol consumption. Objective To describe mortality due to oral and pharyngeal cancer in Chile between 2002 and 2010. Method Ecolo...
Background:
The pleiotropic effects of statins, such as immunomodulation and anti-inflammatory effects, may also improve periodontal conditions. The aim of the present study is to assess the effectiveness of a dentifrice medicated with 2% atorvastatin in improving clinical periodontal parameters as a complement to non-surgical periodontal treatmen...
The purpose of this study was to measure and compare the tonic electromyographic (EMG) activity of the temporalis and masseter muscles following placement of the tongue either on the palate or in the floor of the mouth during swallowing and maximal voluntary clenching (MVC). Thirty healthy dental students with natural dentition and bilateral molar...
Objectives: Evaluate the effect on the application of low level laser therapy, in patients that have been previously intervened with a sagittal ramus split osteotomy and present neurosensory impairment due to this surgery, compared with placebo.
Study Design: This preliminary study is a randomized clinical trial, with an experimental group (n=17)...
The anterior mandibular body is an anatomical area that is often subjected to surgery such as for installation of osseointegrated implants, mentoplasty, genioplasty, fractures, among others. The presence of vessels that penetrates through foraminas at its midline from the lingual table has been described. Tooth loss in the anterior mandibular zone...
The anterior mandibular body is an anatomical area that is often subjected to surgery such as for installation of osseointegrated implants, mentoplasty, genioplasty, fractures, among others. The presence of vessels that penetrates through foraminas at its midline from the lingual table has been described. Tooth loss in the anterior mandibular zone...
Aim(s):
To explore the associations between the presence of periodontal pathogens and the expression of toll-like receptors (TLR-2 and TLR-4) in the placental tissue of patients with hypertensive disorders compared to the placentas of healthy normotensive patients.
Material and methods:
A case-control study was performed. From a cohort composed...
The effect of the Volatile Sulfur Compounds (VSC) on the periodontal tissues, specifically at the RANKL/OPG level has not been elucidate and there is little literature published on this subject.
Background: The effect of the Volatile Sulfur Compounds (VSC) on the periodontal tissues, specifically at the RANKL/OPG level has not been elucidate and there is little literature published on this subject. Aim: To explore if the VSC levels measured in the oral cavity of patients with moderate or severe chronic periodontitis are correlated with the...
Purpose:
To assess whether adolescents with periodontitis presented with higher scores for non-psychotic psychosocial disorders than control subjects without periodontitis.
Materials and methods:
A case control study (n = 160) nested in a well-defined adolescent population (n = 9,163) was performed using the 28-item Spanish version of the Genera...
Aim(s):
To explore the relationship between biomarkers of systemic inflammation in plasma and gingival crevicular fluid in early pregnancy and the subsequent development of pre-eclampsia in patients with periodontitis.
Materials and methods:
A case-control study was performed. From a cohort composed of 126 pregnant women, 43 normotensive healthy...
Objective: To determine if maternal periodontal clinical status, body mass index (BMI) and its variation during pregnancy are associated with increased levels of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-) and C-reactive protein (CRP) in plasma. Material and Methods: This clinical study included a total of 56 pregnant women between 18...
The risk of periodontal defects after the extraction of third molars continues to challenge clinicians.
Intervention trials, including subgingival scaling and/or root planing, were systematically reviewed. Data sources included the Cochrane Oral Health Group Trials Register and MEDLINE. The primary outcome was postoperative change in pocket probing...
Background: The investigation of subgingival microflora in type 2 diabetic patients with periodontitis presented conflicting results. Aim: To determine the presence of Porphyromonas gingivalis, Tannerella forshytia, Treponema denticola and Aggregatibacter actinomycetemcomitans in subgingival biofilm of patients with diabetes type 2 and to relate it...
Aim: The aim of this clinical study was to evaluate and to compare the efficacy in reducing the dentine hypersensitivity of an 8% arginine, calcium carbonate, 1.450 ppm sodium monofluorophosphate dentifrice with topical application and twice-daily brushing, with a negative control toothpaste containing calcium carbonate and 1.450 ppm fluoride as MF...