Valentina Pacella

Valentina Pacella
Institut des Maladies Neurodegeneratives | IMN · Neurofunctional imaging group (GIN)

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18
Publications
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116
Citations

Publications

Publications (18)
Article
Full-text available
The diverging evidence for functional localization of response inhibition within the prefrontal cortex might be justified by the still unclear involvement of other intrinsically related cognitive processes like response selection and sustained attention. In this study, the main aim was to understand whether inhibitory impairments, previously found...
Article
Full-text available
Motor awareness is a complex, multifaceted construct involving the awareness of both (i) one’s motor state while executing a movement or remaining still and (ii) one’s motor abilities. The analysis of neurological syndromes associated with motor disorders suggests the existence of various different components which are, however, integrated into a m...
Article
Full-text available
Personal neglect is a disorder in the perception and representation of the body that causes the patients to behave as if the contralesional side of their body does not exist. This clinical condition has not been adequately investigated in the past as it has been considered a symptom of unilateral spatial neglect, which has mainly been studied with...
Article
Full-text available
Neuropsychological disturbances in the sense of limb ownership provide unique opportunities to study the neurocognitive basis of body ownership. Previous small sample studies that showed discrete cortical lesions cannot explain why multisensory, affective, and cognitive manipulations alter disownership symptoms. We tested the novel hypothesis that...
Preprint
Full-text available
Stroke significantly impacts quality of life. However, the long-term cognitive evolution in stroke is poorly predictable at the individual level. There is an urgent need for a better prediction of long-term symptoms based on acute clinical neuroimaging data. Previous works have demonstrated a strong relationship between the location of white matter...
Preprint
Full-text available
Motricity is the most commonly affected ability after a stroke. While many clinical studies attempt to predict motor symptoms at different chronic time points after a stroke, longitudinal acute-to-chronic studies remain scarce. Taking advantage of recent advances in mapping brain disconnections, we predict motor outcomes in 62 patients assessed lon...
Preprint
Full-text available
Motricity is the most commonly affected ability after a stroke. While many clinical studies attempt to predict motor symptoms at different chronic time points after a stroke, longitudinal acute-to-chronic studies remain scarce. Taking advantage of recent advances in mapping brain disconnections, we predict motor outcomes in 62 patients assessed lon...
Preprint
Full-text available
Personal neglect is a disorder in the perception and representation of the body that causes the patients to behave as if the contralesional side of their body does not exist. This clinical condition has not been adequately investigated in the past as it has been considered a symptom of unilateral spatial neglect, which has mainly been studied with...
Article
Full-text available
The anarchic hand syndrome refers to an inability to control the movements of one’s own hand, which acts as if it has a will of its own. The symptoms may differ depending on whether the brain lesion is anterior, posterior, callosal or subcortical, but the relative classifications are not conclusive. This study investigates the role of white matter...
Preprint
Full-text available
Neuropsychological disturbances in the sense of limb ownership (DSO) provide a unique opportunity to study the neurocognitive basis of the sense of body ownership. Previous small sample studies focused on discrete cortical lesions and modular accounts, which cannot explain the modulations of DSO by multisensory, affective and cognitive manipulation...
Preprint
Full-text available
The anarchic hand syndrome refers to an inability to control the movements of one’s own hand which acts as if it had a will of its own. The symptoms may differ depending on whether the brain lesion is anterior, posterior, callosal or subcortical, but the relative classifications are not conclusive. This study investigates the role of white matter d...
Article
Anosognosia for hemiplegia is a multifaceted syndrome that has a detrimental impact on the patient. Various theories based on behavioural and neuroanatomical data have been proposed to explain the mechanisms underlying the symptoms. These approaches have resulted in the development of a number of different proce- dures aimed at reducing symptoms or...
Article
Full-text available
Being aware of one's own ability to interact socially is crucial to everyday life. After a brain injury, patients may lose their capacity to understand others' intentions and beliefs, that is, the Theory of Mind (ToM). To date, the debate on the association between ToM and other cognitive deficits (in particular executive functions and behavioural...
Chapter
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Motor awareness is the acknowledgment of (i) one's motor state while executing a movement or remaining still and (ii) one's motor abilities. The integrated contribution of different networks involving the parietal cortex, medial and lateral frontal regions, and subcortical structures gives rise to motor awareness. The damage to these structures or...
Article
Full-text available
The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that con...
Article
Full-text available
Executive functions refer to high-level cognitive processes that, by operating on lower-level mental processes, flexibly regulate and control our thoughts and goal-directed behavior. Despite their crucial role, the study of the nature and organization of executive functions still faces inherent difficulties. Moreover, most executive function models...
Preprint
Full-text available
The rare syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural networks th...

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Projects

Projects (2)
Project
Study the impact of brain disconnections and cerebral recovery on visual neglect in humans and non-human primate (Saimiri sciureus)
Project
Applications are invited from highly motivated researchers for a postdoctoral position immediately available in the Neuropsychology Laboratory (NPSY-Lab.VR - http://sites.hss.univr.it/npsy-labvr/), led by Prof. Valentina Moro, at University of Verona, Italy. Prof. Moro’s lab research activity is focused on the study of body, space and action representations in the brain and spinal cord injured patients. Prof. Moro’s lab applies cutting-edge methodologies to lesional studies, DTI and Bayesian analysis. The position will be founded under the PRIN project “Motor sociality through the lens of error monitoring. Behavioural and neurophysiological studies in healthy and brain-damaged people”. Applicants should be expert and independent in designing and conducting EEG studies on brain-damaged and spinal cord injured patients, with particular reference to social, body and action cognition. The initial appointment is for one year, renewable for up to 3 years, with a net salary of 1,613 euros per month. Application Deadline: Feb 6, 2020, at 1:00 PM (Rome time) Interview: Feb 12, 2020, at prof. Moro’s Office (Skype interviews are accepted) Starting Date of the position: Feb 14, 2020 The complete call can be found at https://www.univr.it/it/concorsi/assegnisti-di-ricerca/assegni-di-ricerca/0/7408 Applications must be submitted sending an email at ufficio.protocollo@pec.univr.it Further details about the position Responsibilities/skills of the applicant: - experience in designing EEG experiments - experience in analysing EEG data - knowledge in body, action and space representations literature - neuroimaging and electrophysiological techniques - neuropsychological assessment of brain-damaged patients - English language Qualifications: - PhD - Research activity in the disciplinary sector: M-PSI/02 PSYCHOBIOLOGY AND PHYSIOLOGICAL PSYCHOLOGY. - Team working attitude For any Inquiry, please write to prof. Valentina Moro: valentina.moro@univr.it