Uwe Wollina

• MD
• Former Head of Department at Städtisches Klinikum Dresden

Malignant tumors of the female reproductive system are a serious health and social problem, as they are the second most common cause of death among women, after breast cancer. Their incidence has increased dramatically during recent years, probably due to the different sexual habits and changes in the prevalence of HIV/ AIDS and HPV virus carriers,...

Introduction: Facial esthetics are important for self-esteem. Undesired submental fat (SMF) deposits lead to an unappealing submental profile associated with aging and overweight. Compound ATX-101 is a proprietary formulation of purified synthetic deoxycholic acid for pharmacological submental contouring. Review areas covered: This reviews covers...

The Bulgarian Society of Dermatologic Surgery (BULSDS.com) already seven years opens its doors, again in March at the Grand Hotel Millennium / Shakespeare Hall. With the opportunity to unveil the scientific our scientific forum over two consecutive days – the 14th and 15th March, this year we are making a return to our original concept, whereby we...

Filler zählen zu den am weitesten verbreiteten Werkzeugen der minimal- invasiven ästhetischen Medizin. Schwerpunkt die die Gesichts- Rejuvenation, aber auch an Hals, Dekolleté, Oberarmen und Händen kommen sie zum Einsatz. Filler auf der Basis von Hyaluronsäure sowie biostimulatorische Filler wie Poly-L-Milchsäure oder Kalziumhydroxylapatit werden b...

Im Rahmen der Alterung des Gesichtes nimmt das untere Gesichtsdrittel einen wichtigen Platz ein. Veränderungen der Ligamente und Retinaculae cutis, des dermalen Bindegewebes sowie der Fett- Kompartimente führen zur Ausbildung sog. Hängebäckchen und zu ästhetisch störenden Modifikationen der Kinn-Region. Anatomische Grundlage und allgemeine Hinweise...

Editorial

Fillers are among the most widely used tools in minimally invasive aesthetic medicine. The main focus is on facial rejuvenation, but they are also used on the neck, décolleté, upper arms and hands. Fillers based on hyaluronic acid and biostimulatory fillers such as poly-L-lactic acid or calcium hydroxyapatite are the preferred choice. Their sequent...

The lower third of the face plays an important role in facial ageing. Changes in the ligaments and retinaculae cutis, the dermal connective tissue and the fat compartments lead to the formation of so-called sagging cheeks and to aesthetically disturbing modifications of the chin region. The anatomical basis and general information on filler injecti...

Editorial

Die Behandlungsmöglichkeiten der Psoriasis der Gesichtshaut werden beschrieben.

Dreidimensionale anatomische Modelle entstanden in Europa im 17. Jahrhundert. Herausragende Wachsmodelle wurden in Norditalien gefertigt, um die medizinische Ausbildung trotz des Mangels an Sektionen zu verbessern. Die Herstellung dieser Modelle wurde im ausgehenden 17. und im 18. Jahrhundert in sogenannten Instituten für Künstliche Anatomie organi...

Vitiligo is an autoimmune disorder with a complex genetic and epigenetic aetiology, characterised by progressive skin depigmentation. Recent advancements in artificial intelligence (AI) have greatly impacted the understanding, diagnosis, and treatment of vitiligo. The genetic basis of vitiligo is linked to multiple single nucleotide polymorphisms (...

Background: The earlobe plays a significant role in framing the face and complementing the appearance of earrings, hairstyles, and other facial features. In addition to the growth of the earlobes with the aging process, other changes can compromise the shape, size, and overall youthful appearance of this region. The main changes are evidenced by th...

Claws and nails belong to the epidermal skin appendages, with nails developing later than claws during primate development. Both have also been depicted in fine arts. Claws can be found in illustrations of the cavemen and the devil. Nails became a subject of painting and sculptures from the Renaissance. We discuss several examples of fine arts from...

Läuse sind blutsaugende obligate Ektoparasiten. Beim Menschen treten die Pediculosis capitis (Pediculosis humanus capitis), die Pediculosis corporis (Pediculosis humanus humanus) und die Phthiriasis pubis (Pthirus pubis) auf. Die Erkrankungen zählen weltweit zu den häufigsten Infestationen. Die Übertragung erfolgt fast ausnahmslos durch engen Körpe...

Dermal fillers first gained interest in the late 19th century, but their safety and efficacy were inadequate. But the development of fillers continued and is going on. Temporary fillers like cross-linked hyaluronic acid are widely used nowadays. Biostimulatory semi-permanent fillers like poly-L-lactic acid and calcium hydroxylapatite offer an incre...

Periorifical dermatitis (POD) is a papular, chronic inflammatory skin disease commonly seen in women in their 2nd to 4th decade of life. The major differential diagnosis is persistent acne. In children, POD is less common than in adults. In infants and preschoolers POD is rare. We performed a narrative review for POD in children ≤6 years of age. Di...

The smile is a complex human facial expression, most commonly associated with joy. We present a detailed view on Leonardo Da Vinci's painting of Saint John the Baptist, between 1516 to 1516, which illustrates a smiling saint, which has evoked multiple explanations and theories. Discussing Da Vinci's concept of painting as science media and the two...

Editorial

Periorifical dermatitis (POD) is a papular, chronic inflammatory skin disease commonly seen in women in their 2nd to 4th decade of life. The major differential diagnosis is persistent acne. In children, POD is less common than in adults. In infants and preschoolers POD is rare. We performed a narrative review for POD in children ≤ 6 years of age. D...

The increasing incidence of malignant melanoma (MM) has raised significant concerns in the medical community. Within the MM subtypes, amelanotic melanoma (AM) stands out as a rare and highly aggressive form, representing between 1-8% of all MM cases. We present an exemplary case that illustrates the challenges of late diagnosis of AM, which was mis...

Editorial

Konferenzbericht.

Editorial

Hair loss also known as alopecia is a common condition in dermatological practice. Hair loss can be categorized as either cicatricial, which involves the permanent destruction of hair follicles, or non-cicatricial. The most common underlying systemic factors that contribute to hair loss are nutrition, endocrine imbalance, drugs, infections, maligna...

We are pleased to introduce in this issue of Clinics in Dermatology a new section entitled "Art in Dermatology", which explores the interface between the visual arts and dermatology. This contribution focuses on the architectural structure known as a church spire, that sits atop a church tower, and which has lent its name to a dermatologic sign. Ke...

Sporotrichosis, a neglected zoonotic subcutaneous mycosis, emerges as a major public health challenge in South America, with Brazil leading the ranking as the most endemic country for this disease worldwide. The actual uncontrolled spread of the disease is based on the greater virulence and adaptation of the species Sporothrix brasiliensis to felin...

Lichen planus is a common pruritic, inflammatory disorder of skin with an autoimmune background. It affects <1% in the general population. The disease has significant comorbidities that must be considered in a holistic approach. Skin and skin adnexae, mucosa, eyes, and esophagus may be affected. There are various clinical subtypes in addition to cl...

Lichen planus is a common pruritic inflammatory disorder of the skin with an autoimmune background. It affects < 1% of the general population. The disease has significant comorbidities that must be considered in a holistic approach. Skin and skin adnexa, mucosa, eyes, and the esophagus may be affected. There are various clinical subtypes in additio...

Lächeln ist eine mimische Ausdrucksform mit vielen Nuancen. Verschiedene Gesichtsmuskeln sind am Vorgang des Lächelns beteiligt. Die Wissenschaft unterscheidet bestimmte Typen des Lächelns. Einfluss nehmen nicht allein Muskulatur und Weichteilgewebe, sondern auch die Hartgewebe des Gesichtsschädels und des Zahnapparats. Krankheiten können sich nega...

Infantile cavernous hemangioma is a benign vascular tumor in childhood. Cavernous hemangiomas have a tendency of slow enlargement with subsequent complications such as ulceration and bleeding. We report a case of a large cavernous hemangioma affecting the median upper lip in an 11-year-old girl. The lesion was growing and painful on pressure. The p...

Cheilitis is a common inflammatory disorder of vermillion and adjacent skin of the lips. A special type is angular cheilitis. The disease is of mixed etiology, mostly with bacterial and fungal components. Angular cheilitis may be a clinical sign for an underlying disease. It has two age peaks, one during childhood and another in adults. It becomes...

The gluteal region if of importance in esthetic medicine. A common adverse event in esthetic liposuction of the thigh and the infragluteal fold (“banana fold”) is gluteal ptosis. We analyzed our data on liposuction for female patients with lipedema grade II and III and liposuction of dorsal thighs and the infragluteal fold. Surprisingly, most of ou...

Diese Frage stellt sich VOR jeder Entscheidung einer ästhetischen Behandlung. In unserer Selbstbetrachtung sind wir dabei nicht frei von äußeren Einflüssen. Das liegt einerseits auf der Hand, da über unsere körperliche Erscheinung nonverbale Kommunikation stattfindet. So erleben und erfahren wir auch Rückmeldungen von unserem Gegenüber. Altersabhän...

Dermal fillers are among the most versatile tools in esthetic medicine. A broad range of temporary, semipermanent, and permanent filler products is on the market. We performed a narrative review on spontaneous and induced degradation of dermal fillers in vitro and in vivo. Hyaluronic acid-based fillers are the most frequently used temporary fillers...

The contour of upper arms is defined by humerus bone, muscles (M. biceps brachii, M. triceps brachii, M. brachioradialis, deltoid muscle) and soft tissue. The esthetics of upper arms are characterized by sexual dimorphism. The female arms are ideally characterized by a cylindric shape with smooth transitions to the posterior plane, the deltoid plan...

The role of cosmetics in acne is Janus-faced. From the patient’s perspective cosmetics are often associated with aggravation of acne. These believes do not translate in less common use of cosmetics at all. Not all moisturizers are created for inflamed skin. A higher number of emulsifiers in over the counter products can even lead to dryness since e...

Pediatric patients in the emergency unit often present with muco-cutaneous symptoms. Most muco-cutaneous findings are not life-threatening, but it is crucial to identify those dermatoses with urgent need of treatment. In this review, we present infectious and non-infectious pediatric disorders with muco-cutaneous red-flag signs for a potential seve...

Background: Tinea pseudoimbricata is a variant of tinea incognito with multiple erythematous concentric rings (Ring in a ring) and pruritus. Misuse of topical corticosteroids is a major exogenous factor. Aim: We provide an overview on published cases and report the first case series from Romania. Patients and methods: A narrative review of the lite...

»Memento mori« und »Vanitas« spielen nicht nur in der Religion, sondern auch in der Kunst eine wichtige Rolle. Eine Blüte erlebten sie in der Kunst im Barock. Aber auch gegenwärtige Künstler setzen sich mit Sterben und Tod auseinander. Diese Auseinandersetzung spielt auch in der Dermatologie eine Rolle, obwohl der Blick von außen auf das Fachgebiet...

Das Lipödem ist eine Erkrankung mit einer charakteristischen Fettverteilungsstörung an den Extremitäten und Lipohypertrophie. Leitsymptom ist der Schmerz. Wie das Lipödem diagnostiziert wird und welche aktuellen Daten es zur Therapie und Pathogenese gibt, erfahren Sie in diesem Beitrag.

It is about the role of fine arts in medical education.

Diaper dermatitis (DD) is an umbrella term with different clinical presentations, pathophysiology, treatments, and outcomes. The major subtypes include irritant contact dermatitis and candida-associated DD. In case of atypical presentation or unresponsiveness to treatment, other differential diagnoses should be considered. Although DD can occur at...

Die Pediculosis capitis (Kopflausbefall) ist Folge der Infestation mit dem blutsaugenden Ektoparasiten Pediculus humanus var. capitis. Der wesentliche Übertragungsweg ist der direkte Kontakt Kopf zu Kopf, gemeinsam genutzte Kopfbedeckungen kommen ebenfalls in Betracht. Der Altersgipfel der Erkrankung liegt im Schulalter zwischen sechs bis zwölf Jah...

Der Italiener Bassi hatte bereits 1835 einen Pilz als Ursache einer tödlichen Erkrankung der Seidenraupen identifiziert. Die medizinische Mykologie begann 1839 mit der knappen Beschreibung des Favus-Erregers durch Schönlein. Zu dessen Zeiten wurden Pilze eher als Zufallsbefunde in humanen Geweben angesehen. 1842 erbrachte Remak durch einen Selbstve...

Die Acne keloidalis nuchae zählt zu den chronische-entzündlichen Dermatosen der Haar-Talgdrüseneinheit mit Betonung der Haut des Nackens und des Hinterkopfs. Sie tritt am häufigsten unter jungen Erwachsenen mit einem Fitzpatrick-Hautyp ≥ IV auf. Männer sind deutlich häufiger betroffen als Frauen. Die granulomatöse neutrophile oder lymphozytäre Entz...

Skin microbiota is an integral part of the human immune system. Staphylococcus aureus is one of the essential components of the normal flora. Approximately 20-30% of healthy individuals are persistently colonized with S. aureus, whereas the remainders are considered low-level intermittent carriers. Despite these natural aspects of existence, S. aur...

Editorial

Plastikabfälle sind ein wachsendes Problem für Umwelt und Gesundheit. Im letzten Jahrzehnt hat Mikroplastik mit einer Größe ≤ 5 mm vermehrte Aufmerksamkeit erhalten. Mikroplastik kommt in Gewässern, Böden und der Atmosphäre vor. Die perorale Aufnahme vor allem über die Nahrungskette und inhalative Aufnahme sind beim Menschen nachgewiesen. Mikroplas...

Frontal fibrosing alopecia (FFA) was described first in 1994 by Kossard as an entity. The disease is now regarded as a subtype of lichen planopilaris (LPP). The regression of the fronto-temporal hairline is considered as a typical clinical sign. Currently the diagnosis FFA/LPP becomes more frequent. More than 80 % of all cases are postmenopausal Ca...

Literature review on alopecia and treatment.

Editorial

Two cases of acquired lymphedema after COVID-19 vaccination with an mRNA vaccine are reported and a brief overview on published cases of secondary lymphedema after various COVID-19 vaccines is provided.

Sandstürme aus der Sahara zeigen in Europa ihre Wirkung – nicht nur meteorologisch. Mit dem Staub gelangen auch Mikroben auf die Reise. Darunter finden sich auch opportunistische und human-pathogene Bakterien. Die Auslösung oder Verschlechterung pulmonaler und kardiovaskulärer Erkrankungen sowie die Meningokokken-Meningitis sind bekannte Folgeerkra...

A Yemeni woman in her fifties presented with a 2-year history of progressive disfiguring enlargement of the nose with fleshy lesions on the margin of the nose and the lips. Similar lesions developed slowly on the eyelids and proximal thighs. Clinical examination showed multiple, asymptomatic, smooth, lobulated and indurated violaceous papules and n...

Die Bekleidung als »zweite Haut« steht in einem engen Wechselverhältnis zur menschlichen Haut und beeinflusst Mikroklima, Mikrobiom, und das Haut-assoziierte Immunsystem. Bekleidung kann protektive Wirkungen zeigen, aber auch zum Auftreten oder der Aggravation von Dermatosen führen. Diesen 2 gegensätzlichen Gesichtspunkten in Bezug auf die menschli...

Importance Inconsistent reporting of outcomes in clinical trials of rosacea is impeding and likely preventing accurate data pooling and meta-analyses. There is a need for standardization of outcomes assessed during intervention trials of rosacea. Objective To develop a rosacea core outcome set (COS) based on key domains that are globally relevant...

Pleomorphic dermal sarcoma is an uncommon cutaneous malignancy. It is a tumor of elderly patients with a clear male predominance in the head-and-neck region. It has a potential of relapses and metastatic spread. We represent a case series of 16 patients with a mean age of 82 years. Only two patients were females. Relapses were observed in two pati...

Hochwasser und Überschwemmungen treten weltweit auf. Unter allen Naturkatastrophen sind sie diejenigen mit der höchsten Mortalität. Infolge der klimatischen Veränderungen dürfte ihre Häufigkeit weiter zunehmen. Flutkatastrophen haben nicht allein immense Auswirkungen auf Ökonomie und Infrastruktur, sondern auch auf die öffentliche Gesundheit. Syste...

Editorial

Das Lipödem ist eine Erkrankung mit einer charakteristischen Fettverteilungsstörung an den Extremitäten und Lipohypertrophie. Leitsymptom ist der Schmerz. Wie das Lipödem diagnostiziert wird und welche aktuellen Daten es zur Therapie und Pathogenese gibt, erfahren Sie in diesem Beitrag.

Der Surrealismus entstand als intellektuelle und künstlerische Bewegung am Ende des Ersten Weltkriegs in Paris. Seinen Höhepunkt hatte er zwischen den beiden Weltkriegen. Zwei der Protagonisten, Apollinaire und Breton, verfügten über einen medizinischen Hintergrund. In der vorliegenden Arbeit geht es um Bezüge der surrealistischen Malerei zur Derma...

Webinar der GÄCD zum Thema Altern und Longevity

Editorial

Tagungsbericht der Dresdner Dermatologischen Demonstration vom März 2024.

Lichen planus is a common pruritic, inflammatory skin disorder. A hallmark of the disease is Wickham’s striae. The disease occurs in all age groups but it has some noteworthy peculiarities during childhood. In children the incidence is 2-3%. In contrast to adult lichen planus, the pediatric type lacks a closer association to metabolic syndrome. Man...

Drug hypersensitivity in children is rare compared to adults. Children more frequently develop an infection-associated exanthema. Nevertheless, about 95% of children with drug hypersensitivity present with muco-cutaneous involvement. Early recognition typical clinical symptoms are important to reduce morbidity and mortality. We review relevant type...

Landscape as arranged nature reached its preliminary climax in the 18th century with the concept of the English Garden. One of the oldest German examples of an English Garden is in the Saxonian valley of Seifersdorf. It was created by the Countess Christina von Brühl between 1781 and 1791. She arranged an esthetic and educational landscape park wit...

Der persische Wissenschaftler Abū Alī al-Husain ibn Abd Allāh ibn Sīnā, kurz Ibn Sina, ist in der westlichen Welt unter dem latinisierten Namen Avicenna besser bekannt (980–1037). Neben philosophischen, mathematischen, naturwissenschaftlichen und metaphysischen Schriften erschien der »Canon der Medizin«, ein Werk in 5 Bänden. Diese umfassende Samml...

Facial thread lifts have become more popular in recent times. The durability of the rejuvenation effect is about 6–12 months on average. In the hands of the experienced user, the technique is quite safe. Careful, selection of patients is mandatory. More adverse events are seen with non-absorbable vs. absorbable threads. Elderly patients bear a high...

Histiocytomas are common benign tumors of the skin. In contrast, giant histiocytomas are a rarity. We report a 43-year-old male patient, who presented with a 7 × 6 cm large firm tumor on his left lower leg. This was a long-standing lesion, but within the last three months, the tumor developed an exophytic nodule. A skin biopsy revealed an atypical...

Pediatric dermatitis seborrhoica (DS) is a common inflammatory disorder of infancy and adolescence distinct from atopic dermatitis. We performed a narrative review on clinical and therapeutic aspects of the disease. The prevalence varies geographically and can reach up to 10%. There is a slight male predominance. Although etiopathology is not well...

Miliaria is a benign eccrine sweat gland disorder. Several variants of the disease are known. Inflammation and pruritus are optional symptoms. Sweating, climate, and physical activities are of importance in pathogenesis. In pediatric patients there is an age peak within the 1st to 3rd week after birth, but miliaria can occur at any age. In hospital...

Digitale Bildanalyse zur Melanom-Früherkennung

To investigate the efficacy and adverse events of modern adjuvant melanoma PD-1 and BRAF+MEK inhibitors in areal-life setting.

Borreliosis, also known as Lyme disease, is a vector-borne disease caused by different species of the Borrelia burgdorferi complex. It is frequent in Europe and Northern America. The major vectors are ixodoid ticks. Paediatric borreliosis is common and peaks in children between five to nine years. In Europe, the leading symptom of early infection i...

A 39-year-old obese man visited one of us for concerns regarding multiple skin coloured and pigmented skin tags clustered on the neck, axillae and medial thighs and measured 2–7 mm. He had associated acanthosis nigricans in the same areas. Skin tags on the medial thighs were distributed bilaterally symmetrically in a linear pattern over acanthosis...

Scabies is a human ectoparasitosis caused by Sarcoptes scabei var. hominis. World-wide around 300 million patients are affected. Infants and children have the highest incidence rates. Poverty and overcrowding are social factors contributing to a higher risk of transmission and treatment failure. The leading symptom of the infestation is itch. Compl...

Self-inflicted dermatoses (SID) are not uncommon in dermatological practice. They can be classified into those associated with hidden or denied underlying behavior and those without hidden or denied underlying behavior. Malingering and factitious disorders are the most common of the first subgroup. Skin picking and related syndromes of compulsive a...

The event has taken place on 16 March 2024 at the Grand Millennium Hotel - Sofia, Shakespeare Hall. The organization strives every year to provoke the attention of specialists in the field of dermatology, dermatological surgery, oncosurgery, oncodermatology, plastic surgery and pharmacology, future ones and all those interested in the scientific as...

In der westlichen Welt hat Kunst im Krankenhaus eine lange Tradition, die bis ins Mittelalter reicht. Über das schmückende ästhetische Element hinaus fördert Kunst auch Wohlbefinden und Heilung. Diese positive Wirkung ist für Patienten und ihre Angehörigen ebenso spürbar wie auch für die Mitarbeiter. Beispiele traditioneller und moderner Kunst werd...

The 6th National Congress of the Bulgarian Society of Dermatological Surgery was again a succesful event with 176 participants. The event was hold on 16 March 2024 at the Grand Millennium Hotel - Sofia, Shakespeare Hall. The organization strives with each passing year to provoke the attention of specialists in the field of dermatology, dermatologi...

Moulagen sind individualisierte dreidimensionale Abbildungen von Erkrankungen des menschlichen Körpers zur studentischen Lehre und medizinischen Ausbildung. Sie entstanden im 19. Jahrhundert und erreichten ihre Glanzzeit an der Wende zum 20. Jahrhundert bis zu den 1930er Jahren. In Dresden ist durch Johannes Werther ab 1903 eine umfangreiche Kollek...