Uwe E. Berger

Uwe E. Berger
Medical University of Vienna | MedUni Vienna · Klinische Abteilung für Allgemeine Hals-, Nasen-, und Ohrenkrankheiten

MBA
Establishing Pollen Networks worldwide

About

152
Publications
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2,924
Citations
Additional affiliations
January 2000 - present
Medical University of Vienna
Position
  • Head of researchgroup

Publications

Publications (152)
Article
An increasing prevalence of allergic diseases and asthma is registered worldwide. The numbers rise especially high in countries with a high degree of urbanization. An extensive literature search was performed to present the most important factors that influence the development of an allergy in an urban environment. Therefore, air pollution, with sp...
Preprint
Background: Allergic rhinitis (AR) is a major non-communicable disease that affects the health-related quality of life (HRQoL) of patients. AR is significantly related to asthma also affecting HRQoL. However, data on HRQoL and symptom control in AR patients with comorbid asthma are lacking. Objective: To assess the differences of symptom control an...
Article
Background Functional iron deficiency facilitates allergy development and amplifies the symptom burden in allergy sufferers. Previously micronutrients were selectively delivered to immune cells with beta-lactoglobulin as carrier (holoBLG), resulting in immune resilience and allergy prevention. Objective The clinical efficacy of a FSMP (food for sp...
Article
A multitude of consequences from global warming and environmental pollution can already be seen for nature and humans. The continuous burning of fossil fuels leads to rising temperatures and rising water levels causing extreme weather phenomena like heat waves and flooding. Increasing levels of air pollution also cause adverse health effects. This...
Article
Full-text available
In 2016, the highest birch ( Betula spp.) pollen concentrations were recorded in Kraków (Poland) since the beginning of pollen observations in 1991. The aim of this study was to ascertain the reason for this phenomenon, taking the local sources of pollen in Poland and long-range transport (LRT) episodes associated with the pollen influx from other...
Article
Full-text available
The concept of treatment of an allergy with the offending allergen was introduced more than a century ago. Allergen immunotherapy (AIT) is the only disease modifying treatment of allergic diseases caused by inhalational allergens and insect venoms. Despite this, only few AIT products have reached licensure in the US or an official marketing authori...
Article
In 2016, the highest birch (Betula spp.) pollen concentrations were recorded in Kraków (Poland) since the beginning of pollen observations in 1991. The aim of this study was to ascertain the reason for this phenomenon, taking the local sources of pollen in Poland and long-range transport (LRT) episodes associated with the pollen influx from other E...
Article
Full-text available
Background Grass pollen allergy is the most widespread pollen allergy in the world. It still remains unknown in which aspects and in which extent symptoms from grass pollen allergy differ throughout the grass pollen season, although individual sensitization profiles of persons concerned are known for a long time. Methods The crowd-sourced symptom...
Article
Full-text available
Mobile Health (mHealth) uses mobile communication devices such as smartphones and tablet computers to support and improve health‐related services, data flow and information, patient self‐management, surveillance, and disease management from the moment of first diagnosis to an optimized treatment. The European Academy of Allergy and Clinical Immunol...
Article
Full-text available
Ragweed Pollen Alarm System (R-PAS) has been running since 2014 to provide pollen information for countries in the Pannonian biogeographical region (PBR). The aim of this study was to develop forecast models of the representative aerobiological monitoring stations, identified by analysis based on a neural network computation. Monitoring stations wi...
Article
Full-text available
Background: Pollen allergies affect a significant proportion of the population globally. At present, Web-based tools such as pollen diaries and mobile apps allow for easy and fast documentation of allergic symptoms via the internet. Objective: This study aimed to characterize the users of the Patient's Hayfever Diary (PHD), a Web-based platform...
Article
The grass pollen season was monitored at the Biological Station Lake Neusiedl (Burgenland, Austria) during 2017, 2018 and 2019 by means of a Hirst-type volumetric pollen and spore trap. While the start, end, duration and peaks of the pollen seasons varied between the years, both showed a late occurrence of grass pollen in the air with more than 20...
Article
Standard Hirst-type automated pollen and spore traps are used in aerobiology to assess ambient pollen concentrations with a focus on allergenic taxa, which are wind-pollinated. The relationship of insect to wind pollinated pollen concentrations has not been examined. We analysed the pollen data from the pollen seasons (1 April–31 August) 2008–2017...
Article
Full-text available
Background: The effectiveness of allergen immunotherapy (AIT) in seasonal and perennial allergic rhinitis (AR) depends on the definition of pollen exposure intensity or time period. We recently evaluated pollen and symptom data from Germany to examine the new definitions of the European Academy of Allergy and Clinical Immunology (EAACI) on pollen...
Preprint
Full-text available
BACKGROUND Pollen allergies concern a significant proportion of the population globally. Today, online tools such as pollen diaries and mobile applications allow an easy and fast documentation of allergic symptoms via the internet. OBJECTIVE This study aimed to characterize the users of the Patient´s Hayfever Diary, to apply different symptom scor...
Article
Full-text available
Mugwort pollen allergy is frequent in parts of Europe. As mugwort pollen contains only one major allergen, Art v 1, which harbors only one T cell epitope, we employed mugwort pollen allergy as a model to study allergen-specific T cell responses. However, after 2004, we noticed a drastic decrease in the T cell responses to Art v 1 and eventually it...
Article
The pollen spectra of air and surface soil samples from a rooftop (at 14 m) and from ground level (at 1.6 m) in the suburbs of Vienna (Austria) were compared. Two soil samples and two air samples were taken on four different days to account for possible differences: in winter when no pollination occurred (reference day), in spring during the main f...
Poster
Full-text available
A Parlagfű Pollen Riasztási Rendszer (Ragweed Pollen Alarm System (R-PAS)) 2014 óta nyújt információt a Pannon Biogeográfiai Régióban (PBR) lévő országok légterének pollenkoncentrációjáról. Tanulmányunk célja, egy, az aerobiológiai hálózat mérésein alapuló előrejelzési modell kifejlesztése neurális háló segítségével. A modell elkészítéséhez a PBR-b...
Article
Full-text available
Background: It is recommended to position pollen monitoring stations on rooftop level to assure a large catchment area and to gain data that are representative for a regional scale. Herein, an investigation of the representativeness of pollen concentrations was performed for 20 pollen types in the pollen seasons 2015-2016 in Vienna for rooftop and...
Article
Background Google Trends (GT), a Web‐based surveillance tool, explores the searching trends of specific queries via Google and is proposed to reflect the real‐life epidemiology of allergic rhinitis and asthma. However, the validation of GTs against pollen concentrations is missing at the country level. Objectives In the present study, we used GTs...
Article
Full-text available
Background: Allergy immunotherapy is still the only treatment of pollen allergy, providing a long-term effect. Clinical trials with pollen allergic patients are in need of validated, high quality pollen data and forecasts in order to grant comparability and to adhere to scientific standards. The aerobiological part of clinical trials remained hithe...
Article
Background: This study compared a rapid home-based up-dosing schedule for sublingual immunotherapy (SLIT) drops containing tree pollen allergens with two previously established schedules. Furthermore, the clinical effect of the SLIT was investigated with respect to patients’ first pollen season under treatment. Methods: In this open-label, prospect...
Article
Full-text available
Google Trends (GT) describes the variation of the relevant interest of internet searches toward medical conditions and related symptoms. Allergic rhinitis symptom levels result from the intensity of exposure to aeroallergens in combination with relevant medication use. We analyze data from Germany to examine the relationship between hay fever-relat...
Article
Full-text available
Purpose of Review The definition of a pollen season determines the start and the end of the time period with a certain amount of pollen in the ambient air. Different pollen season definitions were used for a long time including the use of different terms for data and methods used to define a pollen season. Recently suggested pollen season definitio...
Presentation
Full-text available
Poster presentation "Personal Allergy Symptom Forecasting System (PASYFO)"
Article
Full-text available
Background: Online pollen diaries and mobile applications nowadays allow easy and fast documentation of pollen allergy symptoms. Such crowd-sourced symptom data provides insights into the development and the onset of a pollen allergy. Hitherto studies of the symptom load index (SLI) showed a discrepancy between the SLI and the total pollen amount o...
Article
Background: Clinical efficacy of pollen allergen immunotherapy (AIT) has been broadly documented in randomized controlled trials. The underlying clinical endpoints are analysed in seasonal time periods predefined based on the background pollen concentration. However, any validated or generally accepted definition from academia or regulatory authori...
Article
Full-text available
The drivers of spatial variation in ragweed pollen concentrations, contributing to severe allergic rhinitis and asthma, are poorly quantified. We analysed the spatiotemporal variability in 16-year (1995–2010) annual total (66 stations) and annual total (2010) (162 stations) ragweed pollen counts and 8 independent variables (start, end and duration...
Article
Full-text available
Background: Google Trends (GT) searches trends of specific queries in Google, which potentially reflect the real-life epidemiology of allergic rhinitis. We compared GT terms related to ragweed pollen allergy in American and European Union countries with a known ragweed pollen season. Our aim was to assess seasonality and the terms needed to perfor...
Article
Background The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergens exposure time‐periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end as proposed by the European...
Article
Full-text available
Background Grasses release the most widespread aeroallergens with considerable sensitization rates, while different species produce several pollen concentration peaks throughout the season. This study analyzed the prevalence of grass species in three different European city areas and compared the flowering period of these species with daily pollen...
Article
Full-text available
Background The GA²LEN chamber has been developed as a novel mobile allergen exposure chamber (AEC) allowing standardized multicenter trials in allergy. Hitherto, subjective nasal symptom scores have been the most often used outcome parameter, but in standardized modern trials objective parameters are preferred. Despite its practicability, the objec...
Poster
Full-text available
Ragweed Pollen Alarm System (R-PAS) has been running since 2014 to provide pollen information for countries in the Pannonian Biogeographical Region (PBR), being the epicentre of ragweed infestation in Europe. R-PAS was initiated by the Hungarian Aerobiological Network with the aim of creating 3-day forecast of daily pollen concentrations and visual...
Article
Background: Birch pollen-related apple allergy is among the most prevalent food allergies in adolescent/adult individuals and mainly results from sensitization to the major birch pollen allergen Bet v 1 and subsequent cross-reaction with the apple protein Mal d 1. However, specific immunotherapy with birch pollen has inconsistent effects on apple...
Article
In a recently published paper (Pfaar et al., 2016), a Task Force of the Immunotherapy and Aerobiology and Pollution Interest Groups of the EAACI suggested specific criteria for the definition of pollen exposure times for three types of pollen events: (a) Pollen Season (PS) start and end, (b) high pollen season (or Peak Pollen Period-PPP) start and...
Article
Full-text available
Aim: The European Commission Cooperation in Science and Technology (COST) Action FA1203 “SMARTER” aims to make recommendations for the sustainable management of Ambrosia across Europe and for monitoring its efficiency and cost effectiveness. Present study analyses geographic and temporal variations in atmospheric Ambrosia pollen, with the goal of p...
Article
The pollen content of the air in an office was assessed together with the dust on the floor and on the desktops as well as the pollen content outside of the building on rooftops and at ground level. The whole pollen spectrum was evaluated (35 different pollen types) with focus on the major aeroallergens. The air samples were measured with Hirst-typ...
Article
Full-text available
Background: Pollen forecasts are highly valuable for allergen avoidance and thus raising the quality of life of persons concerned by pollen allergies. They are considered as valuable free services for the public. Careful scientific evaluation of pollen forecasts in terms of accurateness and reliability has not been available till date. Objective: T...
Article
Full-text available
The aim of this study was to investigate possible effects of landscape design on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy from Uzbekistan where green areas have been changed during the last two decades by a State program. Sera from two different generations of Uzbek (n=58) and, for control purpose...
Article
Pollen information is of great importance in the everyday life of pollen allergy sufferers and substantially supports in allergen avoidance. Nowadays, pollen information is distributed also via mobile applications (apps). Those apps provide different features, but should conform to a catalogue of criteria, that are essential for users. Those criter...
Article
Pollen information as such is highly valuable and was considered so far as a self-evident good free for the public. The foundation for reliable and serious pollen information is the careful, scientific evaluation of pollen content in the air. However, it is essential to state and define now the requirements for pollen data and qualifications needed...
Article
Background: Clinical efficacy of pollen allergen immunotherapy has been broadly documented in randomized controlled trials. The underlying clinical endpoints are analysed in seasonal time periods pre-defined on the basis of the background pollen concentration. However, any validated or generally accepted definition from academia or regulatory auth...
Article
Background: Grasses (Poaceae) are one of the largest plant families and are distributed worldwide. Grass pollen allergy is one of the most important pollen allergies affecting large parts of the population worldwide. The grass pollen season itself is special since it is caused by the flowering of various grass species that present unique profiles...
Article
Full-text available
Background: Field clinical trials of pollen allergy are affected by the impossibility of predicting and determining individual allergen exposure because of many factors (eg, pollen season, atmospheric variations, pollutants, and lifestyles). Environmental exposure chambers, delivering a fixed amount of allergen in a controlled environmental settin...
Conference Paper
Full-text available
COST SMARTER aims to develop new innovative solutions for the the sustainable management of Ambrosia artemisiifolia L. (ragweed) in Europe and to assess their cost- effectiveness. Several recent studies undertaken by members of COST SMARTER have examined temporal and spatial variations in airborne Ambrosia pollen at different scales, which can be u...
Article
Background The Austrian pollen information service distributes pollen forecasts and offers various options (webpages, a mobile “Pollen” app, interviews for newspapers, radio, TV and information for the press agency) to support and inform pollen allergy sufferers in Austria in the best way to help to avoid their allergen. These services are well rec...
Conference Paper
Full-text available
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive multifactorial disease with limited treatment options.
Article
Pollen are an important component of outdoor and indoor air. Especially in the perspective of the importance of allergens and pollutants and as a consequence their impact on health, they must be included in air quality assessments. The assessment of pollen concentrations is an important pillar for pollen information and research. Pollen concentrati...