Usman Ahmad

• Bachelor of Laws
• Student at University of Management and Technology

Therapy-related B-cell acute lymphoblastic leukemia (B-ALL) is a rare disease associated with poor cytogenetics and inferior survival outcomes. In this case series, we present two cases of B-ALL following treatment for invasive ductal carcinoma of the breast and squamous cell carcinoma of the tongue, respectively, along with a third case of B-ALL a...

This study examines the Critical Success Factors of housing projects in Karachi due to its unique geographic and industrial environment. This will be done by focusing on this demographic and thus enabling a more thorough and pertinent analysis. In this instance, the sample population consists of project management team personnel in the construction...

Background Autologous hematopoietic stem cell transplantation (Auto-HSCT) is a cornerstone treatment for multiple myeloma (MM). The standard conditioning regimen includes high-dose melphalan, commonly administered at 200 mg/m² (Mel-200). However, in resource-limited settings, the reduced dose of 140 mg/m² (Mel-140) is often utilized due to concerns...

Purpose: Early autologous stem cell transplant (ASCT) is recommended for transplant eligible multiple myeloma (MM) patients. However, there is a limited data on outcomes of ASCT in patients from low middle income countries (LMIC). The purpose of this study was to report real world outcomes of ASCT in MM patients from a resource constraint country....

Background: ALL is highly curative in paediatric setting but also proving to have good outcomes in adolescent and young adults (AYA) particularly if treated with paediatric inspired protocols and novel agents such as Blinatumomab and Inotuzumab. Availability of these novel agents is limited due to high-cost in resource limited countries and allogen...

Background: Due to ease of access and affordability, globally 4.95 billion people are using the internet for multiple purposes. However, this use has resulted in the emergence of some novel problems. Objective: Our objectives were to find the frequency and distribution of internet addiction by gender and type (public/private sector medical students...

PURPOSE To highlight challenges and cancer care disparities in patients of diffuse large B-cell lymphoma management in resource-constrained settings. MATERIALS AND METHODS This multicenter retrospective study included 738 patients from 12 public and private sector hematology-oncology centers across Pakistan. Patients were divided into limited-reso...

Background High-dose chemotherapy followed by autologous stem cell transplantation is considered a standard treatment approach for patients with relapsed Hodgkin's lymphoma (HL) and non-Hodgkin lymphoma (NHL). The goal of autologous stem cell transplant in relapsed lymphoma is to achieve long-term disease control, i.e., cure, in contrast to disorde...

This research aimed to build a model for estimating the shelf life of dried chilies in vacuum packaging stored at any storage temperature. The shelf-life estimation of dried red chilies was carried out based on the change rate of dried chilies quality parameters using the ASLT (Accelerated Shelf-Life Testing) method with the Arrhenius approach. The...

Acute lymphoblastic leukemia (ALL) during pregnancy necessitates treatment with high-dose chemotherapy, which can threaten the lives of both the mother and fetus. The aim of the treatment not only focuses on selecting and administering optimal chemotherapy with appropriate doses to the mother but also reflects the crucial understanding of the fetal...

Diabetes mellitus is a chronic and heritable condition which grows adverse with date and eventually accelerates numerous difficulties such as end-stage renal disease, cardiac infections and vision problems. Objective: To highlight protein-based hydrogels as a contemporary focus in insulin delivery through the oral cavity. Methods: Novel hydrogels w...

This study investigates the critical success factors (CSFs) and their interplay with project risks in determining the success of housing projects in Karachi, Pakistan, while considering the moderating role of risk management. Analyzing data from 432 project management professionals within Karachi-based housing societies, the study establishes signi...

Purpose: The Pakistan Stock Exchange is a medium for investment in Pakistan financial markets as well as in an international market and give an opportunity to investors in Pakistan to trade shares and contracts through brokers. This research investigates the behavioral factors that influence decision making of investors in PSX that contribute towar...

In this paper we are going to talk about 3D printing technology. 3D printing technology has sparked a paradigm shift in manufacturing, offering unparalleled versatility and customization capabilities across industries. This review delves into the advancements, applications, challenges, and future prospects of 3D printing. Highlighting its transform...

Introduction Allogeneic stem cell transplant has curative potential for many hematological disorders. Building an allogeneic hematopoietic progenitor cell transplant (HPCT) unit requires huge investment, infrastructure, equipment, medical supplies, and training of health care professionals. The key objective of this study is to share our experience...

The work is aimed to evaluate the blood pressure reducing effect of constituents from methanol extract and associated constituents of Tagetes patula flowers in normotensive and L-NAME induced hypertensive rats. The HPLC analysis of methanol extract of Tagetes patula flowers (JFM) resulted in the quantitative identification and percent comparison of...

Shadow education is a term which metaphorically denotes private tuition. The constitution of Pakistan provides for free education for children; however, their dependents (parents) along with children still pay a cost while paying fee for additionally purchased private tuition lessons. This research aims to understand the demand drivers of shadow ed...

Shadow education is a term which metaphorically denotes private tuition. The constitution of Pakistan provides for free education for children; however, their dependents (parents) along with children still pay a cost while paying fee for additionally purchased private tuition lessons. This research aims to understand the demand drivers of shadow ed...

The concept of 'Khudi' derived by Dr. Iqbal is the action centric which is always searching for new dimensions of knowledge for life, values and dignity. It is three dimensional which can be staged or grasped in wholesome at any point in time. The three fundamentals include understanding self, organizing self and committing self. The concept of his...

With the emergence of the smart grid, the distribution network is facing various problems, such as power limitations, voltage uncertainty, and many others. Apart from the power sector, the growth of electric vehicles (EVs) is leading to a rising power demand. These problems can potentially lead to blackouts. This paper presents three meta-heuristic...

Over the last two decades, there have been major advances in imaging, endoscopy, and laparoscopy in the field of gastrointestinal (GI) surgery. GI surgery is the newest sub-specialty branch of general surgery, where enhanced expertise and high-volume centres have made a difference in the outcomes of complex operations. Surgeons can now perform diff...

An intelligent sound-based early fault detection system has been proposed for vehicles using machine learning. The system is designed to detect faults in vehicles at an early stage by analyzing the sound emitted by the car. Early detection and correction of defects can improve the efficiency and life of the engine and other mechanical parts. The sy...

Education is to serve a purpose otherwise it becomes meaningless. Since it creates awareness, therefore, has been the priority of mankind ever since their emergence and will continue to be so in times to come. Society gazes at the end result i.e., how well universities prepare the graduates for their professional lives. This notion decides the very...

The wet processing of robusta coffee starts with harvesting coffee cherries, followed by sorting the cherries, pulping, fermentation, washing, drying, hard skin hulling, bean sorting, and packaging. Soaking fruit before pulping is an alternative for coffee farmers to delay the pulping process if time does not allow it. The fermentation process aims...

Religion is the source of objective moral values and obligations that can also be declared as the fundamental beliefs of true religion. This article develops and unites the scholarly perspectives of Muslims and Christians on moral values to establish harmony, unity, and peace between Muslims and Christians globally and to provide a forum where both...

Background Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) accounts for 25% of acute lymphoblastic leukemia cases in the adolescent and young adult (AYA) age subgroup. It is associated with poor outcomes and is considered a standard indication for allogeneic stem cell transplant (Allo-SCT). Improved outcomes have been report...

Bleomycin is a commonly used cytotoxic agent that has proven its efficacy over the years. Though a common part of many protocols targeting lymphomas and germ cell tumors, it does have some serious adverse effects. Bleomycin is notorious for pulmonary toxicity and very rarely may cause fulminant hyperpyrexia. We describe two cases of classical Hodgk...

A double circuit 765 kV Dasu Transmission Line (TL) of 250 kilometers length has been planned as Pakistan’s first extra high voltage TL in the highlands. Collision risks for birds may be greatest around the Indus River and its tributaries. The study area is 7,951 km 2, Transmission lines, Indus River , stretching from the Dasu Hydropower Project in...

Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hematologic disorder occurring more commonly in children, but there are reported cases in adults as well. It is classified as a primary HLH or secondary HLH, which can occur due to autoimmune diseases, infections, and malignancies. Secondary HLH is a challenge for physicians conce...

Land use type changes the carrying capacity of habitats to support species diversity and maintain viable population. Avian studies provide substantial information about these changes as birds are predictor of ecological disturbances. The current research explored the avian diversity, richness, abundance and their feeding habit in selected habitats...

Urban populations in South Asia are regularly exposed to poor air quality, especially elevated concentrations of fine particulate matter (PM 2.5 ). However, the potential differential burden for the urban poor has received little attention. Here, we evaluate the links between occupation, patterns of exposure to PM2.5, and the impacts at an individu...

Purpose:This article evaluates the impact of project risk management (PRM) and leadership development (LD) on the project success (PS). The aim of the study is to investigate the linkage between PRM and PS, to study the relationship between LD and PS. To evaluate the moderating effect of Risk Manager on relationship between PRM and PS; and between...

Purpose: The study aims to identify the risk factors that are associated with the housing projects in Pakistan based on their relative importance. Moreover, this study intends to highlight the extreme, high and low risks that are involved in housing projects. Design/Methodology/Approach: The study adopts the quantitative research method and conduct...

Purpose: The purpose of this research study is to gain an insight into the role played by Social Media Reviews in capturing Brand Trust and Brand Loyalty. The study has been conducted in the fast food industry (local burger joints) available in Karachi, Pakistan. This research study is quantitative in nature. Design/Methodology/Approach: This resea...

Debulking procedures using aspiration devices have been previously described in the literature to treat vegetations or thrombi on intracardiac structures such as the tricuspid valve. Transcatheter therapy has also been shown to an effective alternative to surgical treatment for managing high risk or non-surgical patients. Furthermore, aspiration pr...

Eventhough coriander ( Coriandrum sativum L.) is one of important spices for Indonesian traditional cuisine, it is mostly imported from others countries. One problem related to imported coriander is its appearance with dark brown color does not meet Indonesians consumers preference. To improve the appearance of imported coriander, the importers usu...

Marketing research theorists have concentrated their focus in studying the emblematic meaning consumers attach to certain brands. One such concept is brand personality. The brand personality scale proposed by Aaker is popular tool for the measurement of different product categories however, its application on retailers has been a rarity. Moreover,...

Background: Identifying pretreatment blood markers that distinguish prognostic groups of patients with advanced pancreatic ductal adenocarcinoma (PDAC) under first-line FOLFIRINOX chemotherapy has the potential to improve management of this condition. Aim of this study was to determine the prognostic utility of a range of pretreatment, inflammatio...

Mangga arumanis tidak hanya digemari di dalam negeri, tapi juga merupakan salah satu komoditas ekspor bagi Indonesia. Namun, masih sulit melakukan ekspor dalam jumlah besar karena umur simpan yang relatif pendek. Untuk meningkatkan volume ekspor diperlukan penanganan pascapanen yang dapat menurunkan laju penurunan mutu dan memperpanjang umur simpan...

18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) plays a pivotal role in the staging, restaging, and surveillance of various bone tumors, including plasmacytomas and osteosarcomas. Solitary plasmacytomas most frequently occur in the bones and are primarily treated with either surgery or radiotherapy....

Environmental contaminants are becoming a growing issue due to their effects on the cryosphere and their impact on the ecosystem. Mountain glaciers are receding in the HKH region and are anticipated to diminish further as black carbon (BC) concentrations rise along with other pollutants in the air, increasing global warming. Air contaminants and BC...

Background: The clinical outcomes of CD34 and CD10 antigens expression in adolescent and young adult (AYA) precursor B-cell acute lymphoblastic leukemia (pre-B-ALL) is not still well established. In the present study, we analyzed the laboratory characteristics and clinical outcomes of 123 AYA pre-B-ALL patients in order to evaluate the possible cl...

In Malaysia, Public Private Partnership (PPP) is one of the tools to develop infrastructure. Although, there are various forms of PPP projects but Build Operate and Transfer (BOT) is commonly used in infrastructural projects. Despite, the benefits of adopting PPP, there are a few issues that require focus of the practitioners and researchers such a...

Public universities are the major source of higher education all over the world. Therefore, competitive public universities play a significant role in producing an effective labour force for society. The basic objective of the study is to examine the mediating role of strategic intent on the relationship between knowledge sharing and competitive ad...

The moderation effect of organizational culture has also been examined. The quantitative approach has been used in data collection, and 182 sample responses have been gathered from the banking industry employees of Pakistan. The data has been analyzed by employing PLS-SEM. The results have shown that transformational and transactional leadership po...

Coriander seeds essential oil have shown some remarkable biological properties and health benefits. The coriander seeds used in Indonesia are imported and also treated with hydrogen peroxide before reaching consumers. Hydrogen peroxide is known to be a strong oxidizer, but so far, there has been no information that explains its effects on the essen...

Primary lymphomas of the female genital tract (PLFGT), are rare comprising of 0.1-1.1 % of extra-nodal lymphomas annually. Our objective was to retrospectively characterize the demographics, clinical presentation, stage at diagnosis, course of treatment and prognosis. We believe that the data will help us and the oncology community at large in gett...

Objectives:To assess the outcomes of Relapsed Hodgkin,Non Hodgkin lymphoma and Multiple Myeloma treated with salvage chemotherapy and Autologous Transplant.

Purpose: To provide evidence-based recommendations for health care professionals on diagnosis and management of diffuse large B cell lymphoma (DLBCL) in resource constraint settings with variable and often limited access to standard of care and advanced diagnostic and therapeutic facilities. Methods: Modified Delphi methodology[1] was used to gener...

Background Despite demonstration of its clear benefits relative to open approaches, a video-assisted thoracic surgery (VATS) technique for pulmonary lobectomy has not been universally adopted. This study aims to overcome potential barriers by establishing the essential components of the operation as well as determining which steps would be most use...

This is the first multicenter study from Pakistan exploring the prevalence, clinical presentations and treatment outcomes of Multiple Myeloma patients. This retrospective study involved data collection from hospital record system of four tertiary care referral hospitals of Pakistan including all patients diagnosed as having Multiple Myeloma from Ja...

Diffuse large B-cell lymphoma (DLBCL) is the commonest non-Hodgkin lymphoma encountered by hematopathologists and oncologists. Management guidelines for DLBCL are developed and published by countries with high income and do not cater for practical challenges faced in resource-constrained settings. This report by a multidisciplinary panel of experts...

Objective: To evaluate the effect of response to first-line chemotherapy on renal functions in multiple myeloma (MM) patients. Study Design: Cross-sectional study. Place and Duration of Study: Shaukat Khanum Memorial Cancer Hospital, Lahore, from Jan 2013 to Dec 2017. Methodology: Multiple myeloma patients with renal impairment (RI) at baseline wer...

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, low grade, malignant fibroblastic tumor. Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by dysregulated production of granulocytic cell line without the loss of their capacity to differentiate. To our knowledge, there is no described association of DFSP with CML i...

Introduction: To report response rates, progression-free survival (PFS) and overall survival (OS) in patients with advanced pancreatic cancer treated with different available chemotherapeutic regimens over 10 years. Materials and methods: This is a retrospective observational study. All patients with locally advanced and metastatic pancreatic ca...

Snake fruit is one of the export potential fruit which is susceptible to fungus. The objectives of this study are to analyze the effect of irradiation and chitosan coating on snake fruit damage caused by Thielaviopsis paradoxa and to determine the best treatment that can be used to control T. paradoxa fungus attack on snake fruit during storage. Th...

The budgetary pressures, scarcity of resources, and incessant increases in the demand for public services have driven the Malaysian government to involve the private sector in the development of infrastructure through public–private partnership (PPP) projects. Despite the benefits of PPP projects in different regions, including Malaysia, various PP...

Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm characterized by Philadelphia chromosome with excessive tyrosine activity leading to uncontrolled proliferation of mature and maturing granulocytes, predominantly neutrophils. If left untreated CML goes though chronic phase, accelerated phase and ultimately Blast Crises. Accelerated p...

Breast cancer is the most common cancer in females and mostly metastasizes to liver, brain, bones, and lungs. It only rarely involves the choroid; signs of choroidal metastases become apparent late in the course of disease and are therefore linked to bad prognosis. These signs are often ignored as benign symptoms. Although many features may overlap...

Acute myeloid leukemia (AML) presenting as myeloid sarcoma (MS) is a rare malignant entity. Sinuses are rare site of myeloid blast deposition, which can lead to pressure effect on surrounding structure leading to architectural effacement with variable clinical symptoms. It usually coincides with the disease onset or relapse. AML harboring AML1-ETO...

Background Takotsubo syndrome (TTS) and its differentiation from anterior wall ST-elevation myocardial infarction on electrocardiography (ECG) has been a debate. Methods Six studies comparing ECG changes in TTS and AW-STEMI were identified. The primary endpoint was reciprocal changes, presence of Q-waves, and QT-interval. An unadjusted odds ratio...

Objectives This study addresses the incidence, trends, and impact of nosocomial infections (NI) on the outcomes of patients admitted with ST-segment elevation myocardial infarction (STEMI) and cardiogenic shock (STEMI-CS) using the United States National Inpatient Sample (NIS) database. Methods We analyzed data from 105,184 STEMI-CS patients using...

Anton syndrome is characterised by visual anosognosia. It results from damage to both occipital lobes, while the anterior visual pathways remain intact. We describe four cases of Anton’s syndrome. First case is that of a 73-year-old woman, who presented with two separate events of intraparenchymal brain haemorrhage, 4 years apart. Her first stroke...

Purpose This study aims to investigate the relationship between institutional trust, dispositional trust and trust in takaful products with the mediating effect of service-provider expertise. Design/methodology/approach The data for this study were collected from 385 takaful policyholders from Lahore and Islamabad, Pakistan. The relationship is es...

Upper cervical osteomyelitis is rare. Its presenting features are fever and neck pain, but rarely it can involve lower nerves. MRI is the main imaging modality, but it is difficult to interpret due to the unique anatomy of C1 and C2 vertebra and complex intervertebral joint. We describe a case of a 67-year-old woman, who presented with the complain...

Objective: To compare the pathological complete response in human epidermal growth factor receptor type 2 (HER-2) positive breast cancer patients getting neoadjuvant chemotherapy with or without trastuzumab. Study design: Retrospective randomised double-arm observational study. Place and duration of study: Shaukat Khanum Memorial Cancer Hospit...

Purpose This study aims to investigate the relationship between institutional trust, dispositional trust and trust in takaful products with the mediating effect of service-provider expertise. Design/methodology/approach The data for this study were collected from 385 takaful policyholders from Lahore and Islamabad, Pakistan. The relationship is es...

AbstrakPenerapan Good Handling Practices (GHP) dan Good Manufacturing Practices (GMP) pada penanganan pascapanen padi di tingkat penggilingan di Indonesia masih rendah, bahkan sebagian besar operator tidak memperhatikan tentang standar mutu beras. Penelitian ini bertujuan untuk mengevaluasi penerapan GHP dan GMP pada penanganan pascapanen padi di t...

This paper was aimed at expatiating the relevance to which falciparum malaria are protected due to various genetically modified factors which include Hemoglobin S, Hemoglobin E, Hemoglobin C, Hemoglobin F, Alpha and beta thalassemia, ovalocytosis, Glucose – 6- Phosphate dehydrogenase deficiency, Human leucocyte antigen (HLA) – BW53, DRBI 1302, DQBI...

It is important to differentiate between ACEi induced angioedema and anaphylaxis as the pathogenesis and treatment are different. We report a case where a patient was reinstated on Lisinopril on hospital admission who then developed angioedema on day 3 that subsequently resolved spontaneously on withdrawal of the medication with no cardiorespirator...

Tomato waste products (peels and seeds) are rich source of nutrients and bioactive substances, which play a significant role in enhancing the nutritional profile and prolonging shelf life. For this purpose, the effect of tomato waste powder (TWP) at different replacing levels (2, 4 and 8 %) on the physico-chemical, rancidity and organoleptic proper...

In spite of the fact that inflammation has been regarded as a localized orgeneralized defensive component of the body to different types harmful stimuli, there hasbeen becoming confirmation of its strong part in initiation or progression of different ailmentsparticularly related with cancer. Objectives: Aim of this study was to recognize the patter...

Muslim scholars in the field of tafsīr and fiqh right after the time of the Last Prophet (s.a.w.) interpreted the Qur’ān by using certain methodologies that led to the emergence of principles to derive messages from the Qur’ān. Muslim jurists particularly Ḥanafī have developed, among others, Ishārat al-Naṣṣ as a principle to interpret the Qur’Én an...

Objective: To compare blood pressure lowering effects of angiotensin II type I receptor blocker candesartan cilexetil incomparison with calcium channel blocker amlodipine in essential hypertensive patients. Study design: Randomized, open-labeled,prospective comparative study. Place and duration: The study was carried out in the department of pharma...

Citrus is one of important fruits in Indonesia and its production increases every year. However, postharvest equipment for citrus is very limited, leading to low postharvest technology utilization. The objective of this research was to develop a real-time quality evaluation system using a color CCO camera, to be used as an image sensor and processi...