Uruakpa Kelechi

• PhD Student at University of Calabar

Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experiment. These rats were randomly assigned into 5 groups, each containing 5...

Background: The ear and face are indispensable and distinctive features for hearing and identification. Objectives: This study was designed to generate anthropometric data of the ear and facial indices of females of Efik and Ibibio children in Cross River and Akwa Ibom States, show morphological and aesthetic differences and ethnicity. Methods: A t...

The study aimed at elucidating the potency of aqueous extract of Talinum Triangulare on the hippocampal neurons, astrocytes as well as assessing short term memory of scopolamine-induced Alzheimer's type rats. Fifty-four Wistar rats (180-200g) were used for the study; thirty experimental rats were randomly grouped into five, each containing six rats...

Background: Oxidative stress augmented with progressive age, causes changes in mitochondrial DNA, mitochondrial disruption and more oxidative trouble. This process is facilitated in Alzheimer's disease by the pathology of αβ amyloid and activated microglia. Objectives: The present study compared the potentials of aqueous extract of Telfairia occide...

Anthropometry of the digits, palms and feet provides data that reveals the relative distribution of dermal ridge among people in different geographical zone. Dermatoglyphic pattern of the left hand of Annang ethnic group in Akwa Ibom State, Nigeria was carried out to provide dermatoglyphic informations and interrelationship existing among this ethn...

Astrocytes are small star-shaped glial cells that maintain normal human brain physiology including secretion of several active compounds and the formation of blood brain barrier. Reactive astrocytes support regenerating axons and also actuate some genes responsible for the induction of synapse formation. In this study, the effect of aqueous extract...

Astrocytes are small star-shaped glial cells that maintain normal human brain physiology including secretion of several active compounds and the formation of blood brain barrier. Reactive astrocytes support regenerating axons and also actuate some genes responsible for the induction of synapse formation. In this study, the effect of aqueous extract...

Cognitive dysfunction is one of the major health problems including Alzheimer’s that is debilitating in nature. Neuroprotections are strategies and relative mechanisms that are able to defend the central nervous system against neuronal injury due to acute or chronic neurodegenerative disorders. This study elucidated the potentials of aqueous Telfai...

Neurotoxicity is caused by physical, chemical or biological agents which exert an effect on the structure or function of the nervous system. Drugs of abuse, including Diazepam are common, and have been known to cause neurotoxicity.The hippocampus which plays a critical role in the formation, organization and storage of memory is the most affecte...

This study aimed at elucidating the effects of moringa oleifera seed on acetaminophen (paracetamol) induced hepatotoxicity in wistar rats. Thirty two adult wistar rats were distributed into four treatment groups of eight animals each. Group A received normal chow and distil water, group B received 600mg/kg of moringa oleifera, group C received 6g/k...

This study aimed at elucidating the effects of moringa oleifera seed on acetaminophen (paracetamol) induced hepatotoxicity in wistar rats. Thirty two adult wistar rats were distributed into four treatment groups of eight animals each. Group A received normal chow and distil water, group B received 600mg/kg of moringa oleifera, group C received 6g/k...

Zingiber officinale is one of the most widely used spices in the world for food additives., zingiberenol and α-farnesene. It is one of the medicinal herbs used to treat several ailments such as cold, headache, nausea, stomach upset, diarrhoea digestive, gastrointestinal disturbances, rheumatic complains, asthma and parasitic infections. The liver i...

Zingiber officinale is one of the most widely used spices in the world for food additives. It contains zingiberone, shogaols, gingerols, pandols, β-phellandrene, curcumene, cineole, geranyl acetate, terphineol, terpenes, borneol, geraniol, limonene, β-elemene, zingiberol, linalool, α-zingiberene, β-sesquiphellandrene, β-bisabolene, zingiberenol and...

Abstract: Breast cancer is the most common cancer occurring in women among all other types of cancer. The incidence in most continents such as Africa variesin region and its cause is not ascertained in Nigeria. WHO estimated the incidence of breast cancer in 2002 for Nigeria to be 90.7/10,000 for males and 100.9/10,000 for females and the mortalit...

Zingiber officinale commonly known as ''Ginger'' is a rhizome of the monocotyledonous perennial plant. Ginger is used as a remedy for treating many ailments such as arthritis, painful menstrual periods, nausea etc and contains sesquiterpenoids and monoterpenoids. The sesquiterpenoids include (-) zingiberene as the main component, lesser β-sesquiphe...

Background: Azadirachta indica is a tree with most of the parts having various medicinal values. It is however popular because of its high potencies, as antimalarial and anti-fertility agents, which the locals still exploit.Objective: We investigated the effect of the methanol leaf extract on the serum levels of the pituitary-gonad hormones and the...