Umile Giuseppe Longo

Campus Bio-Medico University | unicampus · Orthopaedics and Traumatology Unit

Background: The treatment of patients affected by recurrent anterior shoulder instability has received more attention in the last ten years, focusing on the management of bone loss, which is crucial in predicting postoperative recurrence risk. Recently, various bone grafting techniques and different fixation methods have been developed to preserve...

The shoulder is a highly complex joint, and injuries to this structure can severely impair its functionality, making rehabilitation crucial. Wearable systems offer innovative, non-invasive solutions for accurate and accessible monitoring during rehabilitation. Moreover, the use of multiparametric solutions to monitor both shoulder movements and vit...

Active life monitoring via chemosensitive sensors could hold promise for enhancing athlete monitoring, training optimization, and performance in athletes. The present work investigates a resistive flex sensor (RFS) in the guise of a chemical sensor. Its carbon ‘texture’ has shown to be sensitive to CO2, O2, and RH changes; moreover, different bendi...

To develop a core outcome set for Achilles tendinopathy (COS-AT) for use in clinical trials we performed a five-step process including (1) a systematic review of available outcome measurement instruments, (2) an online survey on truth and feasibility of the available measurement instruments, (3) an assessment of the methodological quality of the se...

Purpose The aim of this study is to report and discuss the outcomes of clinical, histological and animal studies exploring the application of bio‐inductive collagen implants (BCIs) to partial and full‐thickness rotator cuff tears (PT‐ and FT‐RCTs) in addition to reporting on cost‐related factors. Methods Review of literature was performed using th...

Purpose Implanted devices used in metastatic spine tumor surgery (MSTS) include pedicle screws, fixation plates, fixation rods, and interbody devices. A material to be used to fabricate any of these devices should possess an array of properties, which include biocompatibility, no toxicity, bioactivity, low wear rate, low to moderate incidence of ar...

Purpose The objective of this study is to train and test machine‐learning (ML) models to automatically classify shoulder rehabilitation exercises. Methods The cohort included both healthy and patients with rotator‐cuff (RC) tears. All participants performed six shoulder rehabilitation exercises, following guidelines developed by the American Socie...

Purpose The present study reviews the available scientific literature on artificial intelligence (AI)‐assisted ultrasound‐guided regional anaesthesia (UGRA) and evaluates the reported intraprocedural parameters and postprocedural outcomes. Methods A literature search was performed on 19 September 2023, using the Medline, EMBASE, CINAHL, Cochrane L...

Background: Osteoarthritis (OA) is a widely-known disease distinguished by the breakdown of joint cartilage, leading to pain and morning stiffness. In this context, the role of corticosteroids is well known, but there is still a gap of knowledge on the duty of oxygen-ozone therapy (O2-O3). Objective: To evaluate for effectiveness of ultrasound-g...

Total hip arthroplasty (THA) is the gold standard in the treatment of advanced hip osteoarthritis. However, hip resurfacing (HR) arthroplasty may present a viable alternative. The aim of this study was to compare complications, implant survivorship, and functional outcomes between HR and THA, to assess HR as a valid and safe alternative to THA. Inc...

Purpose The purpose of this study was to determine the incidence and hospitalization trends of meniscectomy in Italy from 2001 to 2016. A secondary aim was to investigate the economic burden of the disease on the national healthcare system. Methods Data were extracted from the Italian Ministry of Health's National Hospital Discharge Reports. Diagn...

Background: Glenohumeral degenerative joint disease may affect up to 20% of the population. There are several classification systems of this disease in the scientific literature. Objective: The aim of this study is to determine the reliability and reproducibility of glenohumeral osteoarthritis classification systems. Methods: We assessed gleno...

The application of Artificial intelligence (AI) and machine learning (ML) tools in total (TKA) and unicompartmental knee arthroplasty (UKA) emerges with the potential to improve patient-centered decision-making and outcome prediction in orthopedics, as ML algorithms can generate patient-specific risk models. This review aims to evaluate the potenti...

Background and Objectives: Knee osteoarthritis is a serious burden for modern countries. Timing of surgery and treatment choice are still a matter of controversy in the orthopedic literature. The purpose of this study was to ascertain the incidence and hospitalization trends of high tibial osteotomy in Italy from 2001 to 2016. Materials and Methods...

Shoulder rehabilitation is considered one of the most effective treatments for restoring functional abilities, reducing shoulder pain, and enabling the leading of an active life, improving mobility, strength, and endurance. However, the burdens of travel and time may prevent patients from taking part in such rehabilitation programs. The increased a...

In orthopedics, X-rays and computed tomography (CT) scans play pivotal roles in diagnosing and treating bone pathologies. Machine bulkiness and the emission of ionizing radiation remain the main problems associated with these techniques. The accessibility and low risks related to ultrasound handling make it a popular 2D imaging method. Indeed, 3D u...

Emerging infectious diseases (EIDs) are newly emerging and reemerging infectious diseases. The National Institute of Allergy and Infectious Diseases identifies the following as emerging infectious diseases: SARS, MERS, COVID-19, influenza, fungal diseases, plague, schistosomiasis, smallpox, tick-borne diseases, and West Nile fever. The factors that...

Aims Proximal humeral fractures are the third most common fracture among the elderly. Complications associated with fixation include screw perforation, varus collapse, and avascular necrosis of the humeral head. To address these challenges, various augmentation techniques to increase medial column support have been developed. There are currently no...

Purpose The aim of the present study is to provide a comprehensive review on the surgical outcomes following arthroscopic treatments of partial‐thickness rotator cuff tears (PT‐RCTs) and to compare the postoperative American Shoulder and Elbow Surgeons (ASES) score following in situ transtendon repair and tear completion, followed by repair. Metho...

Background: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, and temporomandibular joints (TMJs) are involved in 39%-78% of patients. Aim: The aim of this systematic review was to assess the effectiveness of conservative approaches in improving TMJ arthritis in children and adolescents affected by JIA. Desi...

Background/Objectives: Recent studies imply that psychological factors and sleep quality play a role in the outcomes of surgical procedures, including in orthopedic surgery. The aim of the present study is to evaluate possible correlations between preoperative depression, anxiety, and quality of sleep and functional 6-month postoperative scores in...

Background Several studies have compared the pros and cons of simultaneous bilateral versus staged bilateral hip and knee replacement but the outcomes of these two surgical options remains a matter of controversy. This study aimed to evaluate demographic features, incidence and hospitalization rates of bilateral one stage total hip and knee arthrop...

Purpose This systematic review aims to provide an overview of the current knowledge on the role of the metaverse, augmented reality, and virtual reality in reverse shoulder arthroplasty. Methods A systematic review was performed using the PRISMA guidelines. A comprehensive review of the applications of the metaverse, augmented reality, and virtual...

Rotator cuff (RC) injury is a common pathology that involves the tearing and weakening of the muscles and tendons that make up RC. Rehabilitation after surgery is crucial for recovery and restoring range of motion (ROM). Currently, the assessment of a patient’s improvement relies on subjective evaluations by physicians. To objectively evaluate the...

Background: Knee osteoarthritis is the most prevalent type of osteoarthritis. Patients frequently encounter pain triggered by movement that evolves into impaired joint function. Needing persistent rest or having night-time pain signifies advanced disease. Qualitative research is considered the most effective method for comprehending patients’ needs...

Recent advances in artificial intelligence (AI) present a broad range of possibilities in medical research. However, orthopaedic researchers aiming to participate in research projects implementing AI‐based techniques require a sound understanding of the technical fundamentals of this rapidly developing field. Initial sections of this technical prim...

Shoulder pain represents the most frequently reported musculoskeletal disorder, often leading to significant functional impairment and pain, impacting quality of life. Home-based rehabilitation programs offer a more accessible and convenient solution for an effective shoulder disorder treatment, addressing logistical and financial constraints assoc...

Background: The etiopathogenesis of ACL rupture is not clarified. The aim of this study is to identify genomic regions and genetic variants relevant to anterior cruciate ligament injury susceptibility that could be involved in non-contact anterior cruciate ligament ruptures. Methods: A systematic review of the literature was performed according to...

Background: Lateral epicondylitis (LE) causes lateral elbow pain due to the overuse of the common extensor tendon. Several therapies have been proposed for pain relief and functional recovery, including physical therapy, minimally invasive injection approaches, and physical agent modalities such as laser therapy. Methods: Our study evaluates the im...

Study design: Epidemiological study. Objective: This study aimed to evaluate the annual incidence of spondylolisthesis requiring surgery in Italy and the epidemiological characteristics of the patients. Background: The health care system continues to incur considerable costs as a result of low-back pain. Segmental instability of the lumbar spi...

Water polo players’ shoulders are exposed to repeated overhead and throwing motions as well as direct and indirect traumas. Shoulder injuries account for over half of all injuries sustained by water polo players. This is a monocentric descriptive epidemiological study on the clinical and radiological presentation of a consecutive series of water po...

Dysregulation of the gut microbiota and their metabolites is involved in the pathogenic process of intestinal diseases, and several pieces of evidence within the current literature have also highlighted a possible connection between the gut microbiota and the unfolding of inflammatory pathologies of the joints. This dysregulation is defined as the...

Background Whether there is a difference in harvesting the semitendinosus tendon alone (S) or in combination with the gracilis tendon (SG) for the recovery of knee flexor strength after anterior cruciate ligament (ACL) reconstruction remains inconclusive. Therefore, this study aimed to assess the recovery of knee flexor strength based on the autogr...

The aim of the present study was to individuate and compare specific machine learning algorithms that could predict postoperative anterior elevation score after reverse shoulder arthroplasty surgery at different time points. Data from 105 patients who underwent reverse shoulder arthroplasty at the same institute have been collected with the purpose...

The 36-Item Short-Form Health Survey questionnaire (SF-36) is a reliable tool to assess the health-related quality of life of patients. If a mean difference between pre-operative evaluation and final follow-up is found to be statistically significant, then the change in score is not random. However, a statistically significant mean change may not c...

Patient-Reported Outcome Measures (PROMs) are standardized questionnaires that gather information on health-related quality of life directly from patients. Since a significant statistical mean change may not correspond to a clinical improvement, there is a need to calculate a considerable change in scores. This is done by the Minimum Clinically Imp...

The purpose of this study was to investigate how lateralization shoulder angle (LSA) and distalization shoulder angle (DSA) are related to clinical and kinematic outcomes after reverse total shoulder arthroplasty. Thirty-three patients were evaluated at least six months postoperatively. The Single Assessment Numeric Evaluation (SANE), Constant Murl...

Background Conservative management has emerged as an attractive option for partial thickness rotator cuff tears (PT-RCTs). A single algorithmic treatment strategy for patients with symptomatic PT-RCT has not yet been developed. This systematic review aims to ascertain whether a conservative approach to PT-RCTs yields positive results in terms of cl...

Few studies have evaluated the effectiveness of shoulder rehabilitation in virtual environments. The objective of this study was to investigate the performance of a custom virtual reality application (VR app) with a stereophotogrammetric system considered the gold standard. A custom VR app was designed considering the recommended rehabilitation exe...

Background Virtual Reality (VR) systems have been increasingly used across several medical fields. A crucial preliminary step for developing optimized VR-based applications for rehabilitation purposes is identifying potential interventions to meet the requirements necessary to satisfy end-users’ needs. This study aims to assess the acceptability, u...

Patients with rheumatic disease may present with a myriad of symptoms, but the most common is undoubtedly chronic or intermittent joint pain. Rheumatic disorders typically affect the musculoskeletal system determining, especially if left untreated, long-term functional damage and deformity. Rheumatisms can be distinguished into two main types on th...

Cervical spondylotic myelopathy (CSM) is a disorder with an increasing prevalence. CSM is an impaired function of the spinal cord caused by degenerative changes in the cervical spine that results in compression of the spinal cord. Symptoms of CSM are the instability of gait, loss of fine motor control of the upper limbs, numbness in the hands, weak...

Neurological pathologies could affect the musculoskeletal system leading to progressive joint destruction. The common characteristic is a deficit in nociceptive sensitivity. This deficit exposes the joint to repeated microtrauma, resulting in microfractures, subluxations, and dislocations. The most common neurological pathologies related to musculo...

Multiple myeloma (MM) is a hematologic neoplasm due to malignant proliferation of plasma cells derived from a single clone. Plasma cell proliferation induced bone resorption causing diffused lytic lesions. The treatment of MM needs a multidisciplinary approach, including also radio- and chemotherapy. Sickle cell anaemia is an inherited haemoglobino...

Lumbar spinal stenosis (LSS) describes a broad spectrum of anatomical, clinical, and radiographic findings. The clinical manifestation of this disease is claudication, lower back and extremity pain, and reduced functionality. The use of a corset is indicated. The surgery aims to decompress the spinal canal and neural foramina, reducing the pressure...

Several endocrine disorders may affect the musculoskeletal system altering bone metabolism and growth. The pituitary gland produces growth hormone (GH): it increases longitudinal height during childhood, promotes mineralization of bone and determines muscle mass hypertrophy. An oversecretion of GH leads to acromegaly and gigantism. GH deficiency le...

The surgical treatment of bone metastases aims to reduce pain, improve function, prevent tumour progression and decrease complications. Surgery is indicated only for patients with an expected survival of 3–6 months. In other cases, palliative treatment is preferred. Wide or marginal excision is always associated with osteosynthesis or prosthetic re...

Advancement in technology, radiotherapy, surgical approaches (anterior, posterior and combined) and technique improved the quality of cervical spine tumour management. Biopsy is necessary to establish the histological diagnosis. There are no precise guidelines concerning cervical spine tumour surgical management; therefore, this surgery needs to be...

Rotator cuff tear (RCT) is a painful, progressive condition resulting from damage to the rotator cuff tendons and is the leading cause of shoulder-related disability. Surgical repair of rotator cuff is an established standard of care (SOC); however, failure of the procedure can occur. In this context, the use of collagen-based bioinductive implant...

Purpose Radiofrequency ablation is an increasingly used surgical option for ablation, resection and coagulation of soft tissues in joint arthroscopy. One of the major issues of thermal ablation is the temperature monitoring across the target areas, as cellular mortality is a direct consequence of thermal dosimetry. Temperatures from 45 °C to 50 °C...

Instability is one of the causes of failure in total knee arthroplasty (TKA). The aim of this study was to analyze the correlation between objective ligament laxity and the clinical outcome of mechanically aligned TKA. Fifty-one knees in 47 patients were evaluated at a minimum follow-up of 6 months. The correlation between the angular displacement...

Aim: The overall aim of this proposal is to ameliorate the care of rotator cuff (RC) tear patients by applying an innovative machine learning approach for outcome prediction after arthroscopic repair. Materials and methods: We applied state-of-the-art machine learning algorithms to evaluate the best predictors of the outcome, and 100 RC patients...

Purpose Rotator Cuff (RC) lesions are classified in full-thickness and partial-thickness tears (PTRCTs). To our knowledge, no studies investigated the mean size of shoulder tendons in healthy and PTRCT patients using MRI scans. The aim of the study was to provide data to obtain and compare the mean value of tendon sizes in healthy and PTRCTs groups...

This review aims to evaluate the usefulness of preoperative education in the orthopedic patient undergoing knee and total hip replacement. The systematic review was conducted by searching the PubMed, Cochrane, CINAHL, and Embase databases from inception to April 2021. Keywords and combinations of keywords were organized according to the PICOs appro...

Monitoring shoulder kinematics, including the scapular segment, is of great relevance in the orthopaedic field. Among wearable systems, magneto-inertial measurement units (M-IMUs) represent a valid alternative for applications in unstructured environments. The aim of this systematic literature review is to report and describe the existing methods t...

The anterior cruciate ligament (ACL) is the most injured ligament of the knee, and the treatment of choice is usually ACL reconstruction. Kinesiophobia refers to an irrational and paralyzing fear of movement caused by the feeling of being prone to injury or reinjury. The aim of the present study is to evaluate the relationship between preoperative...

The rehabilitation of those who have undergone anterior cruciate ligament reconstruction (ACL-R) is a complex process that involves many factors. Physical ability recovery is not the only factor in the return to sport; psychosocial factors such as anxiety, pain response, self-esteem, locus of control, and fear of re-injury also play an important ro...

Scapular dyskinesis (SD) is a condition of loss of normal mobility or function of the scapula. SD is frequently observed in patients with other shoulder disorders, such as rotator cuff (RC) tears. This study evaluates the different presentations in clinical outcomes and range of motions (ROMs) in patients suffering from RC tears with and without SD...

The Shoulder Disability Questionnaire (SDQ) is a Patient-Reported Outcome Measure (PROM) applied to evaluate shoulder surgery outcomes. The purpose of this study is to identify the accurate Minimal Clinically Important Difference (MCID), Substantial Clinical Benefit (SCB) and Patient Acceptable Symptom State (PASS) values for the SDQ score. A total...

This study intended to estimate the annual number of hallux valgus surgical procedures in Italy and the patients’ epidemiological features. A secondary goal was to compare the demographic differences in access to hallux valgus surgery amongst three Italian macroregions. The analysis was conducted by using the National Hospital Discharge Records (NH...