Umarani Balakrishnan

Umarani Balakrishnan
Nehru Memorial College · department of Zoology

M.Sc., B.Ed

About

11
Publications
1,819
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Citations

Publications

Publications (11)
Article
Full-text available
Cancer is one of the most dangerous diseases globally, and it appears due to extreme free radical damage, some chemicals, and a lack of physical activity which dispute causes damage to the cellular DNA, protein, and lipids. A number of treatment methods are available, but they cause unwanted side effects. The use of plant-derived products in the tr...
Article
Full-text available
The traditional medicinal plants are used for treating various diseases including cancer because of their non toxic effect of normal cells and cytotoxic effect on cancer cells. Plant derived compounds have been used in treatment of cancer for many years. India has vast number of herbal plants, in which ayurvedics system of medicine has developed ra...
Article
Full-text available
Traditionally, plants such as Mentha spicata, Plectranthus amboinicus, and Ocimum sanctum from lamiacea were used for anticancer and other medicinal purpose. The present study deals with the analysis of binding affinity mechanism of 10 selected compounds (Apigenin, Benzaldehyde, Eugenol, Geraniol, Limonene, Luteolin, Vanillin, Niacin, Linoleic acid...
Chapter
Viruses have efficient means to survive and broadcast in a number of varieties of hosts such as birds, insects, fish, humans, and other mammals and various cell types with respect to their host distribution, genomic organization, and clinical presentations. Virus may possess DNA or RNA as genome and may follow diverse routes for replication, transc...
Chapter
Full-text available
This chapter presents an investigation of the presence of secondary metabolites in the ethyl acetate extract of Tectona grandis bark extract and the cytotoxic effect against MCF-7 cell lines. Phytochemical compounds were determined by gas chromatography–mass spectrometry (GC-MS) analysis. The cytotoxic activity, morphological assessment of cell dea...
Article
Full-text available
The traditional medicinal plants are used for treating various diseases including cancer because of their non toxic effect of normal cells and cytotoxic effect on cancer cells. Plant derived compounds have been used in treatment of cancer for many years. India has vast number of herbal plants, in which ayurvedics system of medicine has developed ra...
Article
Full-text available
The present study investigated the presence of secondary metabolites in the ethylacetate extract of Pisum sativum seeds and their cytotoxic effects against MCF-7 cell lines. P. sativum is commonly known as green pea comes under Family Fabaceae. The plant has been shown to possess many biological activities including anticancer properties among othe...
Conference Paper
Full-text available
The present study investigated the presence of secondary metabolites in the ethanolic extracts of Pisum sativum seeds and their cytotoxic effects against MCF-7 cell lines. P. sativum also known as green pea, Family: Fabaceae, has long been an important part of a healthy diet due to its contents (protein, starch, fiber, trace minerals, and phytochem...
Conference Paper
Full-text available
Cancer is a serious concern at present. A large number of patients die each year due to cancer illnesses in spite of several interventions available. Development of an effective anticancer therapy is the trending research. Chemical entities present in plants proved to be very potential in effective treatment of cancer. Efforts are in progress to de...
Article
Full-text available
Objective: A huge reservoir of bioactive compounds exists in many species of plants, only a small percentage of which have been examined and continued to be an important source of anticancer agents. Finding new phytochemical compounds with anticancer activity is important to design new drugs. Thus the present study attempted to mine bioactive compo...

Questions

Question (1)
Question
Main ingredient of plant cell wall is cellulose. Our digestive system does not contain cellulase enzyme to digest cellulose. Some people are drinking plant leaves juices (eg. curry leaves, drumstick leaves) for their health benefits. then how digestion will occur? Is cause any side effects?

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Projects

Projects (3)
Project
To gather relevant information in all areas of drug discovery research into resourceful books that will be useful to everyone. E-mail: egbunachukwuebuka@gmail.com Some Books of the project: Elsevier Series on Drug Discovery Updates (Book proposals are being accepted). https://www.elsevier.com/search-results?labels=books&book-series=Drug%20Discovery%20Update Coronavirus Drug Discovery (Vol 1-3) https://www.elsevier.com/books/coronavirus-drug-discovery/egbuna/978-0-323-85156-5 https://www.elsevier.com/books/coronavirus-drug-discovery/egbuna/978-0-323-95574-4 https://www.elsevier.com/books/coronavirus-drug-discovery/egbuna/978-0-323-95578-2 Application of Nanotechnology in Food Science, Processing and Packaging https://link.springer.com/book/10.1007/978-3-030-98820-3 Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches https://www.elsevier.com/books/computer-aided-drug-design-cadd-from-ligand-based-methods-to-structure-based-approaches/rudrapal/978-0-323-90608-1 Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses https://www.sciencedirect.com/book/9780128215562/phytochemistry-the-military-and-health Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations https://link.springer.com/book/10.1007/978-3-030-42319-3 Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes https://link.springer.com/book/10.1007/978-3-030-72999-8 Analytical Techniques in Biosciences (Published) https://www.elsevier.com/books/analytical-techniques-in-biosciences/egbuna/978-0-12-822654-4 Neglected Tropical Diseases and Phytochemicals in Drug Discovery (John Wiley & Sons Canada, Limited, 2020; ISBN: 1119616603, 9781119616603) https://www.wiley.com/en-us/Neglected+Tropical+Diseases+and+Phytochemicals+in+Drug+Discovery-p-9781119616603 Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine (Elsevier, ISBN: 9780128202852; October, 2020) https://www.elsevier.com/books/preparation-of-phytopharmaceuticals-for-the-management-of-disorders/egbuna/978-0-12-820284-5 Drug Development for Cancer and Diabetes: A Path To 2030 (AAP/CRC Press Taylor & Francis, published). https://www.routledge.com/Drug-Development-for-Cancer-and-Diabetes-A-Path-to-2030/Saravanan-Egbuna-Averal-Kannan-Elavarasi-Bahadur/p/book/9781771888608 Phytochemicals as Lead Compounds for New Drug Discovery (Elsevier, ISBN: 9780128178904) https://www.elsevier.com/books/phytochemicals-as-lead-compounds-for-new-drug-discovery/egbuna/978-0-12-817890-4 Natural Remedies for Pest, Disease and Weed Control (Elsevier, ISBN: 9780128193051) https://www.elsevier.com/books/natural-remedies-for-pest-disease-and-weed-control/egbuna/978-0-12-819304-4 Phytochemistry: in vitro and in silico updates (Springer Nature, ISBN: 9780128193051). https://www.springer.com/us/book/9789811369193 Phytochemistry, Vol 1: Fundamentals, Modern Techniques, and Application (Published on the 14th Dec., 2018). https://www.crcpress.com/Phytochemistry-Volume-1-Fundamentals-Modern-Techniques-and-Applications/Egbuna-Chinenye-Ifemeje-Chidi-Udedi-Kumar/p/book/9781771887595 Phytochemistry, Vol 2: Pharmacognosy, Nanomedicine, and Contemporary Issues (Published on the 14th Dec., 2018). https://www.crcpress.com/Phytochemistry-Volume-2-Pharmacognosy-Nanomedicine-and-Contemporary/Egbuna-Kumar-Chinenye-Ifemeje-Vikas-Kurhekar/p/book/9781771887601 Phytochemistry, Vol 3: Marine, Industrial, and Advances (Published on the 14th Dec., 2018). https://www.crcpress.com/Phytochemistry-Volume-3-Marine-Sources-Industrial-Applications-and-Recent/Egbuna-Chinenye-Ifemeje-Kumar-Sharif/p/book/9781771887618 I will also welcome partnerships from similar projects, departments, faculties and universities. Please contact me through egbunachukwuebuka@gmail.com; Phone: +2347039618485
Project
To identify flavonoid rich plants, isolate and evalate their anticancer activity under in vitro and in vivo conditions.