umar Huzaifa

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• Doctor of Philosophy
• Senior Researcher at Near East University

Toxicological evaluation of aqueous extract of Khaya senegalensis stem bark on some liver function parameters of normal rats (100-140g) were critically examined. The albino rats (16) were randomly assigned into four (I-IV) groups each of which contains four rats. They were acclimatised for a week and Khaya senegalensis stem bark extract was adminis...

S-nitrosylation involves the covalent attachment of nitric oxide (NO) to a highly reactive sulfahydryl group of cysteine residues in proteins or peptides and emerges as a key figure in neurodegeneration and prevention of certain forms of cancer. Overproduction of NO appears to abrogate the proliferation of cancer cell lines by activation of p53 and...

The effects of aqueous garlic extract on liver function were studied by assessing the changes in serum activities of alanine aminotransference (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and total bilirubin (TBIL) concentration in albino rats. The doses of 100, 250, 400 and 550mg per kilogram body weight were administered or...

Cassava cyanide effluent arising from cassava processing contaminate soil, leading to increased concentration of cyanide in soil and water, posing a risk to plant, aquatic life, and human health. Hence, the aim of this study is to investigate the impact of abattoir sludge on cyanide concentration of cassava effluent and soils receiving cassava effl...

The growing demand for sustainable and high-performance food packaging has led to the exploration of green nanomaterials as viable alternatives to synthetic counterparts. Traditional packaging materials often struggle to provide sufficient protection against oxygen, moisture, and UV light, which accelerates food spoilage and reduces shelf life. Thi...

This review explores the green biosynthesis of nanoparticles using plant extracts, emphasizing the underlying mechanisms, recent advancements, challenges, and diverse applications of this sustainable technology. Plant-mediated nanoparticle synthesis presents an eco-friendly and cost-effective alternative to conventional methods that often rely on t...

Signalling of calcium ions is vital for the normal physiology and survival of cells. Membrane bound organelles like the mitochondria and many other cell-bound proteins and receptors play significant roles in regulating intracellular calcium levels thus maintaining homeostasis of the external and internal cell environments. The regulation of cellula...

This review explores the impact of probiotics and dietary bioactives on gut microbiota, inflammatory responses, and metabolic well-being. It emphasizes how these bioactive components, particularly probiotics, influence gut health by modulating the gut microbiota, a vital ecosystem of microorganisms that play a key role in health. The paper investig...

The review presents a comprehensive overview of the various bioactive compounds found in ginger, namely gingerols, shogaols, paradols, and zingerone as well as their biological activities. The compounds are responsible for the distinct aroma, flavor, and pharmacological activities such as anti-inflammatory, anti-oxidation, antimicrobial, anti-cance...

The present study aims at evaluating the nutritional value and antioxidant potential of various meat types (beef, pork, chicken, catfish and snails) consumed in Owhelogbo, community in Isoko Local Government, Delta State, Nigeria. The different meat samples were analyzed for nutritional composition and antioxidant properties. The results obtained s...

The aim of the study is to examined fertilizers obtained from poultry manure (PM), poultry manure biochar (PMB), inorganic fertilize (IF), poultry manure + poultry manure biochar (PM + PMB), poultry manure + inorganic fertilizer (PM + IF), poultry manure biochar + inorganic fertilizer (PMB + IF), poultry manure + poultry biochar + inorganic fertili...

This review paper delves into the role of probiotics and food bioactives in influencing gut health and overall well-being, within the context of probiotics and food bioactives, emphasizing their roles in modulating inflammation, gut microbiota, and metabolic health. Probiotics are defined as live microorganisms that confer health benefits to the ho...

This review paper analyzes recent advancements in bio-polymer coatings for probiotic microencapsulation, with a particular emphasis on chitosan and its synergistic combinations with other materials. Probiotic microencapsulation is essential for protecting probiotics from environmental stresses, enhancing their stability, and ensuring effective deli...

Medicinal plants are generally important for the therapeutically active materials that can be obtained from them. Authenticating the herbal products obtained from these medicinal plants and separating adulterants from genuine therapeutic products in order to protect the health of the public and guarantee the reproducible quality of herbal medicines...

Purpose of Review This review summarizes the sources, metabolism and roles of selenium within the human body. Past and recent evidence implicating selenium deficiency as a feature in various cases of cancers is reviewed. Recent Findings Trace elements (micronutrients) are nutrients required in minute concentrations in human physiology. Their signi...

This study examined the phytochemical profile and antimicrobial efficacy of Dyschoristeperrottetii, a plant traditionally used to treat female sterility, fever, malaria, diarrhea, chickenpox, and dysentery. The plant material was identified, dried, pulverized and extracted using cold maceration method. The phytochemical screening of the crude ethyl...

This review aims to provide a comprehensive acumen of food spoilage mechanisms, foodborne diseases, and the commercial dimensions of food preservation and processing. It begins with an exploration of the processes contributing to food degradation, such as enzymatic reactions, microbial growth, and chemical changes, emphasizing their impact on food...

Poly(vinyl chloride) (PVC) has been a fascinating subject for polymer science research. Its characteristics are heightened by its inherent structural faults resulting from direct manufacturing (by free-radical polymerization), which also cause its thermal instability. Some of the fundamental limiting features of PVC have been suggested to be allevi...

The Chinese date or Ziziphus jujuba, is a drupe fruit that depending on the cultivar, can be round, elongated, cherry or plum-sized. The little shrub known as the jujube tree produces the jujube fruits. As a specie of the genus Ziziphus belonging to the Rhamnaceae family of buckthorn plants, this tree is linked to a wide variety of other plants, in...

The constraints of pure PMMA have made the cross-linkage of polymethyl methacrylate (PMMA) an interesting issue to meet application requirements. Cross-linked PMMA offers several advantages over its uncross-linked counterpart, due to its exceptional electrical insulation, chemical stability, clarity, improved heat resistance, superior mechanical pr...

The idea that food and medicine are similar has a long history, many substances have also been used both as food and traditional treatment remedies. Several plant-based therapeutic substances including those obtained from plants like Chrysanthemum morifolium, Lonicera japonica, Crocus sativus, and Lonicera macranthoides, are homologous for use both...

There are multiple linkages in homeostasis and illness between the function and development of the commensal microbiota and the mammalian endocrine system. While the microbiome plays crucial roles in training and maturity of vital host innate and adaptive immune system components, the immune system organizes and protects the essential elements of h...

The aim of this study was to assess the acute and sub-acute toxicity of aqueous and methanol extracts of the root of Tetracera alnifolia as well as the effects on some biochemical parameters in albino rats as many plants used in traditional medicine lack scientific and clinical evidence to support a better understanding of their safety and efficacy...

In this study, we investigate the symmetry analysis and explicit solutions for the Estevez–Mansfield–Clarkson (EMC) equation. Our main objectives are to identify the Lie point symmetries of the EMC equation, construct an optimal system of one-dimensional subalgebras, and reduce the EMC equation to a set of ordinary differential equations (ODEs). We...

The influence of different nitrogen sources, initial pH, and varied inoculum size on the fermentation capacity of Saccharomyces cerevisiae on sorghum wort substrate was investigated. The parameters analyzed included ethanol concentration, pH, specific gravity, and total soluble sugars after 72 h fermentation period using standard methods such as sp...

The Inertial Tseng Algorithm (ITA) and the Fast Iterative Shrinkage-Thresholding Algorithm (FISTA) are well-established methods that provide effective ways to approximate zeros of the sum of monotone operators. In this study, we applied both ITA and FISTA in the restoration process of prostate cancer and osteosarcoma images that were degraded with...

Background: Ovarian cancer is a significant cause of morbidity and mortality among women worldwide. Early detection and accurate diagnosis are crucial for improving patient outcomes. Serum biomarkers, such as cancer antigen 125 (CA-125), have shown promise in aiding the diagnosis and monitoring of ovarian lesions. Objective: This study aimed to ass...

It is well-known that the Tseng algorithm and its modifications have been successfully employed in approximating zeros of the sum of monotone operators. In this study, we restored various thoracic diseases’ computerized tomography (CT) images, which were degraded with a known blur function and additive noise, using a modified Tseng algorithm. The t...

Klebsiella pneumoniae, a member of the Enterobacteriaceae family, naturally resides in the gut microbiome of both healthy humans and animals. This pathogen is frequently found in hospitals and takes advantage of opportunities to cause infections. It is responsible for approximately one third of infections caused by Gram-negative bacteria. This stud...

The optimal enhancement of athletic performance, recovery from exhaustion after exercise, and injury prevention are products of appropriate nutrition. Nutritional supplements that contain proteins, carbohydrates, vitamins, and minerals are frequently utilized in various sports to complement the recommended daily amounts. Several of these supplement...

In the food industry, electrical conductivity is essential for heating processes. The dependence on temperature conductivity of electricity on the outermost layers flow of the nanofluid is the main topic of this paper. Variable electrical conductivity, viscosity, thermo diffusion, thermal radiation and radiation absorption on convective heat and ma...

In this study, a unified auxiliary equation method, which is one of the powerful methods for exploring nonlinear model solutions, is used in the Fokas system, with complex functions representing nonlinear pulse propagation in monomode optical fibers. As a result, we get some solutions, including dark–bright, singular, periodic, bright–dark, Jacobi...

The present study aims to perform a comparative analysis of the plane Couette flow of a couple stress fluid under the influence of magnetohydrodynamics (MHD) using two different methods: the Optimal Auxiliary Function Method (OAFM) and the Homotopy Perturbation Method (HPM). The couple stress fluid is known for its non-Newtonian behavior, where the...

Iron oxide nanoparticles (Fe2O3 NPs) stabilized with Moringa Oliefera were synthesized. The study aimed to investigate the cytotoxic, anti-proliferative potential of Fe2O3 NPs through various assays such as trypan blue and MTT assay. The Moringa Oliefera-mediated Fe2O3 NPs (MO Fe2O3 NPs) were analyzed using a range of techniques, including Fourier-...

The demand for efficient hardware implementations of convolutional neural networks (CNNs) has surged with the proliferation of deep learning applications in various domains such as computer vision, natural language processing, and autonomous systems. Convolutional layers, being the fundamental building blocks of CNNs, are computationally intensive,...

Iron oxide nanoparticles (Fe 2 O 3 NPs) were synthesized utilizing Mentha spicata sourced from Cyprus as a stabilizing agent. The study delved into assessing the antimicrobial, cytotoxic, anti-proliferative, and anti-migratory potential of Fe 2 O 3 NPs through disc diffusion, trypan blue, and 3-[4, 5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium br...

A new type of geopolymer with an iron–oxygen–silicon linkage is synthesized and reported for the first time. The aim was to enable the iron-rich clay material (laterite) as a raw material for the geopolymerization. Iron was used in different ratios ranging 1–3 wt. % in the raw mix designing geopolymer followed by activation with concentrated alkali...

It is well-known that the Tseng algorithm and its modifications have been successfully employed in approximating zeros of the sum of monotone operators. In this study, we restored various thoracic diseases’ computerized tomography (CT) images, which were degraded with a known blur function and additive noise, using a modified Tseng algorithm. The t...

Cancer is one of the major causes of death in the modern world, and the incidence varies considerably based on race, ethnicity, and region. Novel cancer treatments, such as surgery and immunotherapy, are ineffective and expensive. In this situation, ion channels responsible for cell migration have appeared to be the most promising targets for cance...

Cancer is one of the major causes of death in the modern world, and the incidence varies considerably based on race, ethnicity, and region. Novel cancer treatments, such as surgery and immunotherapy, are ineffective and expensive. In this situation, ion channels responsible for cell migration have appeared to be the most promising targets for cance...

Recently, Shehu has introduced an integral transform called Shehu transform, which generalizes the two well-known integrals transforms, i.e. Laplace and Sumudu transform. In the literature, many integral transforms were used to compute the solution of integro-differential equations (IDEs). In this article, for the first time, we use Shehu transform...

Cancer is one of the major causes of death in the modern world, and the incidence varies considerably based on race, ethnicity, and region. Novel cancer treatments, such as surgery and immunotherapy, are ineffective and expensive. In this situation, ion channels responsible for cell migration have appeared to be the most promising targets for cance...

Breast cancer is a common cancer affecting women worldwide, and it progresses from breast tissue to other parts of the body through a process called metastasis. Albizia lebbeck is a valuable plant with medicinal properties due to some active biological macromolecules, and it’s cultivated in subtropical and tropical regions of the world. This study...

Nanoencapsulationof nutraceuticalsand food supplements is a promising approach in nanomedicine field, and the nanoformulation has now become an interesting and alternative delivery system.Encapsulation of nutraceutical to a nano size enables controlled of drugs or nutrients release in a particular time, enhanced their oral bioavailability, thermal...

The growing interest in hybrid nanofluids is due to the synergistic effects of nanoparticles, which could give them better heat transfer properties as compared to base fluids, and conventional nanofluids. Several factors like temperature and volume fraction have been used in explaining the behaviours of hybrid nanofluids, however, the need to inves...

Nano-based particles synthesized via green routes have a particular structure that is useful in biomedical applications as they provide cheap, eco-friendly, and non-toxic nanoparticles. In the present study, we reported the effect of various concentrations of Zinc oxide nanoparticles synthesized using A. lebbeck stem bark extract (ZnO NPsAL) as sta...

This work employs the application of three artificial intelligence (AI) techniques namely; support vector machine (SVM), Hammerstein-Wiener (HW) and multi-layer perceptron (MLP) for predicting the qualitative properties of an anti-Alzheimer agent using high-pressure liquid chromatography technique. The mobile phase (inform of acetonitrile and trifl...

The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of medicinally important plant Allium sativum (garlic) in its aqueous of bulb. The phytochemical tests were conducted using standard methods of analysis. The result of the phytochemical screening showed the presence of flavonoids, alkaloi...

This study was carried out for biosynthesis of gold nanoparticles by using Scytosiphon lomentaria (brown algae) and Spyridia filamentosa (red algae) and compared. Synthesized gold nanoparticles were characterized using the UV-Vis spectroscopy (UV-Vis), Fourier transform infrared (FTIR) and Master Sizer analysis. Macro algae extract involvement in t...

Cancer incidence is still increasing due to inadequate responsive treatments. Inertness and biocompatibility of nanoparticles synthesized using plant extracts have shown therapeutic applications and make it to be a good anti-cancer candidates. This study is a recent novel spotlight that synthesized silver nanoparticle from Ficus ingens leaf extract...

Background Biocompatibility and stability of zinc oxide nanoparticles (ZnO NPs) synthesized using plants is an interesting research area of study in nanotechnology, due to its wide applications in biomedical, industrial, cell imaging, and biosensor fields. The present study reports the novel green synthesis of stable ZnO NPs using various concentra...

Microorganisms have over the years evolved and developed resistance to available antimicrobials. This has cause a great impact to the world over health wise and socioeconomically. They are developing resistance at a very fast rate that current technologies and new drug developments in the pharmaceutical industries are unable to catch up. Therefore,...

"> Silver nanoparticles (AgNPs) synthesis is among the new areas of nanotechnological research and it’s a bit cost effective, pollution freeand environmental friendly compared to other metals used to synthesized nanoparticles. The synthesized nanoparticle was characterized using Atomic Force Microscope (AFM), FTIR, EDX, UV-Vis, Zeta Sizer and anti-...

Little is known about the prevalence and motives of sport drinks use among adolescents and young adult athletes who exercise on regular basis in most football and other games pitches. Therefore, the current study was performed to assess information regarding the use of sport drinks among 440 athletes (23.5±4.62 years of age) in Kano Nigeria. Data w...

The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of medicinally important plant Allium sativum (garlic) in its aqueous of bulb. The phytochemical tests were conducted using standard methods of analysis. The result of the phytochemical screening showed the presence of flavonoids, alkaloids,...

The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of medicinally important plant Allium sativum (garlic) in its aqueous of bulb. The phytochemical tests were conducted using standard methods of analysis. The result of the phytochemical screening showed the presence of flavonoids, alkaloids,...

Background and Objective: Healthy body weight is an important indicator towards prevention of diseases. In the north western part of Nigeria, there is dearth of data on the prevalence of HBV infection among female adolescents. This study was therefore, carried out to determine the effect of body mass index on the sero-positivity of hepatitis B surf...

The effects of aqueous garlic extract on liver function were studied by assessing the changes in serum activities of alanine aminotransference (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and total bilirubin (TBIL) concentration in albino rats. The doses of 100, 250, 400 and 550mg per kilogram body weight were administered or...

An evaporative cooler was developed and assessed with locally available materials. The materials were outsourced and constructed locally within the study area. A daily monitoring of temperature and relative humidity for both ambient and the cooler were recorded using the wet bulb and dry bulb thermometer and digital humidity-temperature meter. The...