Ulrich Gauger

www.statistikhilfe.de

Smoking is a leading cause of head and neck squamous cell carcinoma (HNSCC). However, non-smokers are also affected by HNSCC, and the prognostic factors applicable to older non-smokers with HNSCC are largely unknown. The aim of this study was to determine predictors of overall survival (OS) in patients both with and without a smoking history aged 7...

Introduction and hypothesisThe purpose of this study was to evaluate the sensitivity and specificity of pelvic floor ultrasound (PFUS) in the diagnostic work-up of female urethral diverticulum (UD) and to compare results of PFUS with voiding cystourethrogram (VCUG).Methods We retrospectively reviewed our database of patients, who received VCUG and...

Obejctives Worldwide, the overall cesarean section is rising. Trial of labor after cesarean (TOLAC) is an overall safe option with an immediate impact on neonatal and maternal short- and long-term health. Since the use of prostaglandins in cervical ripening is associated with an increased risk of uterine rupture, mechanical methods as balloon cathe...

Context Retzius sparing robot-assisted radical prostatectomy (RS-RARP) is increasingly being used, but results of pertinent studies on perioperative, functional, and oncological outcomes comparing the Retzius sparing approach with standard robot-assisted radical prostatectomy (RARP) remain inconsistent. Objective To evaluate the effectiveness of R...

In some cases, laparoscopic inguinal hernia repair leads to immobilizing pain. Its chronification and a possible increase of opioid consumption may result. Hence, the local anesthesiological procedure of the Transversus abdominis plane (TAP) block was conducted prior to a variety of surgical procedures. In a previous work, we demonstrated the analg...

Objective To evaluate the efficacy and safety of desmopressin on frequency and urgency in female patients with overactive bladder (OAB) and nocturia. Methods A selective database search was conducted to validate the effectiveness of desmopressin in patients with OAB and nocturia. Preferred reporting items for meta-analyses (PRISMA) guidelines were...

Objective Hearing loss is a highly disabling condition. Cochlear implantation is an established remedy if conventional hearing aids have failed to alleviate the level of disability. Unfortunately, cochlear implant (CI) performance varies dramatically. This study aims to examine the effects of duration of deafness (DoD) prior to cochlear implantatio...

Purpose: Laparoscopic inguinal hernia repair (IHR) may lead to early postoperative pain. Therefore, opioid and non-opioid analgesic agents are often administered in the post-anesthesia care unit (PACU). To reduce the postoperative cumulative need of analgesic medication, as well as to accelerate the physical recovery time, the transversus abdominis...

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Purpose: The transversus abdominis plane (TAP) block is a regional anesthesia technique. Recently, its impact on early, chronic pain and cumulative need of analgesic medication following inguinal hernia repair (IHR) has been investigated. In terms of effectiveness and patient’s safety it remains unclear whether the approach should be conducted preo...

Background: The Milan criteria (MC) are widely used for the indication of liver transplantation (LTx) in hepatocellular carcinoma (HCC). Good long-term results have also been reported following LTx for patients exceeding the MC. In this article, we compare the overall and recurrence-free survival of our patients fulfilling and exceeding the MC acc...

Purpose: Patients suffering from a ventral hernia can be treated by laparoscopic ventral hernia repair (VHR) with the intraperitoneal onlay mesh (IPOM) technique. To reduce early postoperative pain and the analgesic cumulative need for medication (CNM), the transversus abdominis plane (TAP) block has recently been investigated and implemented in he...

Purpose: The transversus abdominis plane (TAP) block is a regional anesthesia technique. Recently, its impact on early, chronic pain and cumulative need of analgesic medication following inguinal hernia repair (IHR) has been investigated. In terms of effectiveness and patient's safety it remains unclear whether the approach should be conducted preo...

Purpose: Patients suffering from a ventral hernia can be treated by laparoscopic ventral hernia repair (VHR) with the intraperitoneal onlay mesh (IPOM) technique. To reduce early postoperative pain and the analgesic cumulative need for medication (CNM), the transversus abdominis plane (TAP) block has recently been investigated and implemented in he...

Introduction: Chronic postoperative inguinal pain (CPIP) is defined as pain impacting daily activities lasting at least 3 months postoperatively. With an incidence of 0.5 to 6.0%, chronic pain affects many patients who underwent inguinal hernia repair (IHR). Early severe postoperative pain has been described as a risk factor for CPIP. Thus, we aim...

Background The Milan criteria (MC) are widely used for the indication of liver transplantation (LTx) in hepatocellular carcinoma (HCC). Good long-term results have also been reported following LTx for patients exceeding the MC. In this article, we compare the overall and recurrence-free survival of our patients fulfilling and exceeding the MC accor...

Background: The Milan criteria (MC) are widely used for the indication of liver transplantation (LTx) in hepatocellular carcinoma (HCC). Good long-term results have also been reported following LTx for patients exceeding the MC. In this article, we compare the overall and recurrence-free survival of our patients fulfilling and exceeding the MC acco...

Objective: To evaluate the complications and results of artificial urinary sphincter (AUS) implantation in women with stress urinary incontinence (SUI). Methods: A selective database search using keywords (1990–2019) was conducted to validate the effectiveness of the AUS in women. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (...

Incisional hernias of the abdominal wall are frequent complications after laparotomy (9-20%) and often need incisional hernia repair (IHR). In order to ensure wound healing and to therefore prevent postoperative short and long term morbidity carrying an abdominal binder (AB) and physical rest is frequently advised. However, there is a lack of evide...

Purpose A colorectal anastomotic leakage (CAL) is a major complication after colorectal surgery and leads to high rates of morbidity and prolonged hospital stay. The study aims to evaluate the benefit of using bilirubin, urobilinogen, pancreas elastase and bile acid in the drain fluid (DF) as a predictive marker for the CAL. Methods From June 2015...

Objective: Postoperative vertigo is a common complaint after cochlear implantation, but published incidence rates differ vastly. The aim of the present study was to investigate both subjective complaints of vertigo before and after cochlear implantation and related vestibular diagnostic tests on cochlear implant candidates. Data sources: We perf...

The study investigated the seasonal courses and intradiurnal patterns of birch (Betula), grass (Poaceae), and mugwort (Artemisia) pollen at two sites in the city of Berlin in 2014 and 2015.

For nearly a decade, the majority of the world’s population has been living in cities, including a considerable percentage of people suffering from pollen allergy. The increasing concentration of people in cities results in larger populations being exposed to allergenic pollen at the same time. There is almost no information about spatial distribut...

PurposeThe study investigated the seasonal courses and intradiurnal patterns of birch (Betula), grass (Poaceae), and mugwort (Artemisia) pollen at two sites in the city of Berlin in 2014 and 2015. Methods The “Motorway Site” was situated at a busy city motorway and the “City Center Site” on the roof of a large hospital. Sampling was undertaken with...

Background Trial of labor after cesarean (TOLAC) is a viable option for safe delivery. In some cases cervical ripening and subsequent labor induction is necessary. However, the commonly used prostaglandins are not licensed in this subgroup of patients and are associated with an increased risk of uterine rupture. Methods This cohort study compares...

Although beech (Fagus) pollen are often disregarded, they play an allergological role. This study focused on pollen season (PS) of European beech (Fagus sylvatica L.) and mean yearly temperatures (T) at two climatically different sites (lowlands vs. Alps) in Germany. Pollen sampling was conducted with 7-day recording volumetric spore traps between...

The presence of hepatocellular carcinoma (HCC) is a significant complication of cirrhosis because it changes the prognosis and the treatment of the patients. By now, contrast-enhanced CT and MR scans are the most reliable tools for the diagnosis of HCC; however, in some cases, a biopsy of the tumor is necessary for the final diagnosis. The aim of t...

Overweight and obesity is a serious health risk in both developed and developing nations. It is a common finding among women in their reproductive age. Half of patients entering their pregnancy in the US have a BMI >25.0 and therefore qualify as overweight or obese. Moreover, there is a tendency towards increased weight gain during pregnancy. Studi...

Einleitung: Die Vorsorgekoloskopie (VK) ist auch 2015 das zuverlassigste Vorsorgeverfahren fur das kolorektale Karzinom. Seit 2005 haben wir in 12 Studien im Rahmen des Berlin Colonoscopy Projects (BECOP) mit uber 20.000 Patienten die unterschiedlichsten Qualitatsparameter der VK an der Charite untersucht. Methoden: Die Qualitat der VK wird am best...

In this study, the seasonally averaged intradiurnal patterns of four different pollen types (Fraxinus, Betula, Poaceae and Artemisia) and the role of traffic volume, air pollution and selected weather parameters were investigated. Measurements were carried out with a 7-day recording volumetric spore trap (Hirst type) near a congested city motorway...

The diagnosis of acute cellular rejection (ACR) after liver transplantation is based on histological analysis of biopsies because non-invasive biomarkers for allograft rejection are not yet established for clinical routines. CD31, CD44, and CXCL9 have previously been described as biomarkers for cross-organ allograft rejection. Here, we assessed the...

Fragestellung: Die Vorsorge-Koloskopie (VK) stellt auch 2015 den Goldstandard der Darmkrebsvorsorge dar. Sie ist das zuverlassigste Verfahren zur Vorbeugung und Fruherkennung des kolorektalen Karzinoms. Seit 2002 ist sie Bestandteil des Vorsorgeprogramms in Deutschland. Seit 2005 haben wir in insgesamt 10 Studien im Rahmen des Berlin Colonoscopy Pr...

Background and study aims: The German screening colonoscopy program is accompanied by a central registry that records the main outcome quality indicators, namely colonoscopy completion rate, adenoma detection rate (ADR), and complication rate. The aim of the present study was to assess the quality of these registry data by comparing them with data...

Hintergrund: Die Qualitat der Vorsorge-Koloskopie (VK) wird am besten durch die Adenom-Detektionsrate (ADR) festgelegt. Die substantielle Variabilitat der ADR zwischen verschiedenen Endoskopikern konnte verschiedene Erfahrung, Fertigkeiten und/oder Ausrustung widerspiegeln. Ziel: Eine Analyse der potentiellen Faktoren, die die Variabilitat der ADR...

Subsquamous intestinal metaplasia (SSIM) has been observed after endotherapy in patients with neoplastic Barrett esophagus (BE). However, it is not clear if SSIM occurs in untreated patients. Incompletely eradicated SSIM could provide a source of recurrent disease; we assessed its prevalence in a large cohort of patients who had not received endosc...

Screening colonoscopy effectiveness is hampered by limited adherence by the general population. The present prospective study was performed to evaluate whether adding capsule colonoscopy to the endoscopic screening options increases uptake. Invitation letters were sent to 2150 persons above the age of 55 insured with a German medical insurance comp...

Pain and bloating following colonoscopy are an underestimated problem, with 30 - 60 % of patients complaining of such symptoms. The use of CO₂ has been shown to significantly decrease pain after colonoscopy in academic hospital-based studies. The aim of the present study was to evaluate whether such an effect can also be seen during private practic...

Background Screening colonoscopy (SC) outcome quality is best determined by the adenoma detection rate (ADR). The substantial variability in the ADRs between endoscopists may reflect different skills, experience and/or equipment. Objective To analyse the potential factors that may influence ADR variance, including case volume. Design 12 134 consecu...

Improvements to endoscopy imaging technologies might improve detection rates of colorectal cancer and patient outcomes. We compared the accuracy of the latest generation of endoscopes with older generation models in detection of colorectal adenomas. We compared data from 2 prospective screening colonoscopy studies (the Berlin Colonoscopy Project 6)...

Fujinon intelligent chromoendoscopy (FICE) is a post-processing imaging technique for increasing contrast of mucosa and mucosal lesions that might lead to improvement in colonic adenoma detection during colonoscopy. Previous studies on similar contrast-enhancing techniques as well as on dye staining have yielded variable and conflicting results. Th...

Hintergrund: Das Fallvolumen korreliert mit der Ergebnisqualitat in einer Vielzahl von medizinischen Prozeduren. Die Qualitat der Vorsorge-Koloskopie (VK) als den effizientesten Test fur die Pravention des kolorektalen Karzinoms wurde durch die Adenom-Detektionsrate (ADR) definiert. Ob das VK-Fallvolumen mit der ADR korreliert, ist bisher prospekti...

Hintergrund: Im Rahmen der Vorsorge-Koloskopie werden unterschiedliche Adenomraten erzielt; die Grunde hierfur sind am ehesten beim Endoskopiker zu suchen (z.B. Ruckzugszeit), jedoch werden auch immer technische Faktoren (bessere Auflosung durch neuere Gerate) ins Feld gefuhrt. Die vorliegende randomisierte Studie uberpruft diese Hypothese anhand z...

In addition to medical, job related, sociodemographic risk factors, and health related behavior, topics that traditionally have been less in the focus of attention in this context, such as biographic data, coping with stress, personality variables, pregnancy related attitudes, fears, and the social network were examined. 589 women between 16(th) an...

This is a report on 10 cases of hepaticojejunostomy (Rodney Smith) with a sutureless technique. The method is very easy and the diameter of anastomosis is more than 5 mm.

Berlin, Humboldt-Universiẗat, Diss., 2002.

Tübingen, Med. F., Diss. v. 31. Dez. 1961.