Uğur Canpolat

Uğur Canpolat
Hacettepe University School of Medicine · Department of Cardiology

M.D., Associate Professor

About

587
Publications
181,450
Reads
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3,598
Citations
Introduction
Dr. Canpolat was graduated from Hacettepe University Faculty of Medicine (2007), Department of Cardiology (2012), Ankara/Turkey and works as a staff electrophysiologist (since 2015) at Arrhythmia and EP Unit of Hacettepe University Department of Cardiology. He studied as a research fellow at Texas Cardiac Arrhythmia Institute at St Davids' Medical Center, Austin, Texas/US (January-June 2019). Scientific interests include cardiac arrhythmias, catheter ablation and CIEDs.
Additional affiliations
January 2019 - June 2019
St. David's North Austin Medical Center
Position
  • Research Associate
April 2018 - present
Hacettepe University
Position
  • Professor (Associate)
March 2015 - March 2018
Hacettepe University
Position
  • Professor (Assistant)
Education
September 2001 - June 2007
Hacettepe University
Field of study
  • Faculty of Medicine

Publications

Publications (587)
Article
Background: Atherosclerotic cardiovascular disease is still the leading cause of mortality for women. Breast cancer screening with mammography is recommended in all women aged over 40 years. Aims: Whether breast artery calcification (BAC) is associated with cardiovascular disease is not clear. We aimed to evaluate the association between BAC and t...
Article
In this issue of the journal, Sciacca et al. (Ref) reported their single center experience in a small non‐randomized observational study about the catheter ablation approach and outcomes in 74 patients with atrial arrhythmia reccurence [atrial fibrillation (AF) (36.5%) and atrial tachycardia (AT) (63.5%)] This article is protected by copyright. All...
Article
Background Infective endocarditis (IE) is a life-threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socio-economic factors might influence its epidemiology, clinical presentation, investigation and management, and outcome, in a large international multi-centre registry. Methods The EurObservation...
Article
Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valv...
Article
Full-text available
Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidea...
Article
Background There were gaps between guidelines and practice when surgery was the only treatment for aortic stenosis (AS). Objectives This study analyzed the decision to intervene in patients with severe AS in the EORP VHD (EURObservational Research Programme Valvular Heart Disease) II survey. Methods Among 2,152 patients with severe AS, 1,271 pati...
Article
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Background The presence of atrial fibrosis has already been known as a risk factor for atrial fibrillation (AF) development. Objective We aimed to evaluate atrial fibrosis with previously defined three different methods, which were cardiac magnetic resonance imaging (C-MRI), echocardiographic strain imaging, and biomarkers, and show the relationshi...
Article
Full-text available
Single coronary artery is a rare congenital anomaly associated with sudden cardiac death even though most of the cases are asymptomatic. Cardiac computerized tomography angiography plays an essential role in establishing the diagnosis of single coronary artery and designating the arterial course. Being aware of coronary anomaly is crucial in some c...
Article
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Purpose: To compare the inter-center cranial computed tomography (CT) acquisition rates, CT findings, CT related radiation dose, and variability of CT acquisition parameters for neurologic events among patients with implantable cardioverter-defibrillator (ICD) or left ventricular assist device (LVAD). Methods: A total of 224 patients [ICD group...
Article
Full-text available
Abstract Objective: We aimed to evaluate the degree of QTc prolongation and associated factors in patients with COVID-19 in association with their usage of hydroxychloroquine(HQ) with or without the combination of azithromycin(AZ) and/or favipiravir(FAV). Methods: This single-center, retrospective study was conducted in a tertiary care university h...
Article
Objective Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory disease which affects many systems, as well as the cardiovascular system. Identifying the coronary involvement like periaortitis, coronary periarteritis and pericarditis is important, as they often cause unfavorable outcomes. Methods Eighty-one patients...
Article
The cover image is based on the Research Article Development and validation of clinical prediction model to estimate the probability of death in hospitalized patients with COVID‐19: Insights from a nationwide database by Ibrahim Halil Tanboğa et al., https://doi.org/10.1002/jmv.26844.
Article
Full-text available
Background and aim Myocardial injury defined by elevation of cardiac troponins (cTn) in the course of coronavirus disease 2019 (COVID-19) pandemic has been reported, though not fully characterized yet. Using the Turkish nationwide centralized COVID-19 database, we sought to determine whether cTn measured within 24 hours of admission may help identi...
Article
Background Powered transvenous lead extraction (TLE) tools are commonly required to remove the leads with long implant duration due to fibrotic adhesions. However, comparative data are lacking among different types of TLE tools. Aim To compare the efficacy and safety of two different rotational mechanical dilator sheaths in retrospectively analyze...
Article
Full-text available
Objective: This study aimed to evaluate the safety of direct oral anticoagulants (DOACs) in patients with non-valvular atrial fibrillation (NVAF) during daily clinical practice. Methods: This was a prospective study conducted between January 01, 2016, and April 01, 2017, in patients aged ≥18 years with a diagnosis of NVAF. We performed the study...
Article
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Backgrounds: In the current study, we aimed to develop and validate the model based on our nationwide centralized COVID-19 database for predicting death. Methods: We conducted an observational study (CORONATION registry). All patients hospitalized with COVID-19 in Turkey between March 11th, and June 22nd, 2020, were included. We developed and va...
Article
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The common ostium of left and right inferior PVs is an extremely rare variant which was only reported in 16 cases undergoing catheter ablation. Thus, electrophysiologists should be careful about such an exremely rare PV variants for the safety and efficacy of ablation. Pre‐procedural CTA is a valuable tool to decide on the ablation strategy in pati...
Preprint
Full-text available
Cryoballoon technology is a well-established method to provide pulmonary vein isolation in the treatment of atrial fibrillation. Additional lesions such as roof line, posterior wall isolation or left atrial appendage isolation also possible with the same technique. We report a case with roof dependent atrial tachycardia successully terminated by us...
Article
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Purpose To present our experience regarding acute and long-term outcomes of left-sided atrioventricular node (AVN) ablation in patients with atrial fibrillation (AF). Methods A total of 47 patients with AF in whom left-sided AVN ablation via retroaortic approach as a first-line approach were enrolled in this retrospective study. Indications for AV...
Conference Paper
Background and Aims: Cardiovascular diseases are still the leading cause of mortality in all over the world. Breast cancer is the most common cancer in women and screening with mammography is recommended in women aged over 40 years. Breast artery calcification (BAC) is associated with cardiovascular diseases. We aimed to evaluate the association be...
Article
We aimed to present the long-term prognostic role of coronary computed tomography angiography (CTA) in a cohort of patients with coronary artery disease (CAD) and noncritical stenosis. A total of 1138 patients who underwent coronary CTA for suspected CAD were included in the study. For the categorization of the coronary atherosclerotic plaque (CAP)...
Article
Full-text available
Purpose The efficacy of cryoballoon (CB) for atrial fibrillation (AF) ablation is still debatable in case of anatomical variations like left common pulmonary vein (LCPV). We aimed to assess the impact of LCPV trunk on the acute and long-term clinical outcomes in patients with CB based AF ablation. Methods We compared a total of 82 AF patients (62....
Article
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Background: Diagnosis and screening of frailty, a condition characterized by an increased vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool which is strongly recommended by healthcare providers concerned with hospitalized elderly population. The data showing the role of frailty in patients infected with COVID...
Article
Full-text available
Novel interventional therapies for heart failure patients are emerging like atrial flow regulator (AFR). Our case showed that endocardial ventricular tachycardia (VT) ablation could be performed safely by passing through the AFR device lumen without additional transseptal puncture in these patients. This article is protected by copyright. All right...
Article
The percutaneous epicardial approach has become an adjunctive tool for electrophysiologists to treat disparate cardiac arrhythmias, including accessory pathways, atrial tachycardia, and particularly ventricular tachycardia. This novel technique prompted a strong impulse to perform epicardial access as an alternative strategy for pacing and defibril...
Chapter
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Wide complex tachycardia (WTC) is an electrocardiographic (ECG) descriptor encompassing all tachycardias (i.e., rhythms with a rate ≥ 100 bpm) with a QRS complex ≥120 msec. The approach to a WTC is frequently challenging, as a wide QRS complex can result from a variety of mechanisms and clinical conditions with very different prognostic and therape...
Article
Background We evaluated the efficacy of a new method in identifying peri‐device leak (PDL) using morphology of the thrombus formed inside the left atrial appendage (LAA) as seen on follow‐up transesophageal echo (TEE). Method A total of 291 consecutive patients undergoing Watchman procedure were included in this analysis. TEE was performed at 45 d...
Article
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Background Diabetes is related with both AF occurence and increased thromboembolic risk. There is scarce data about the outcomes of AF catheter ablation in patients with diabetes. Purpose We aimed to evaluate outcomes of AF catheter ablation in patients with diabetes. Methods All patients underwent AF cryoablation between January 2013 and January...
Article
Full-text available
Background Electrical storm (ES) is defined as 3 or more episodes of sustained ventricular tachycardia (VT) within 24 hours and related with high mortality rates. Catheter ablation is an effective treatment option in patiens with ES. Purpose We aimed to evaluate outcomes of VT catheter ablation in patients with ES. Methods All patients who und...
Article
Full-text available
Background Ablation of ventricular tachycardia (VT) is an effective and safe treatment option in symptomatic patients under antiarrhythmic drugs or patients with frequent ICD therapies. Purpose We aimed to evaluate outcomes of VT catheter ablation in patients with ischemic VT. Methods All of the patients who underwent VT catheter ablation between...
Article
Full-text available
Although pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results can be explained with higher success rates of catheter ablation in restoring and maintaining si...
Article
Full-text available
In the past decade, the use of interventional electrophysiological (EP) procedures for the diagnosis and treatment of cardiac arrhythmias has exponentially increased. These procedures usually require fluoroscopy to guide the advancement and frequent repositioning of intracardiac catheters, resulting in both the patient and the operator being subjec...
Article
Atrial fibrillation catheter ablation has emerged as the most effective strategy to restore and maintain sinus rhythm. The cornerstone of atrial fibrillation ablation is elimination of triggers from the pulmonary veins by pulmonary vein isolation. Nevertheless, some patients may experience atrial tachyarrhythmia recurrences even with permanent pulm...
Article
Background Infective endocarditis (IE) is a life threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socio-economic factors may influence variations in epidemiology, clinical presentation, investigation and management (and their consequence upon clinical outcomes) in a large international multi-cen...
Article
Full-text available
Background Currently available second-generation cryoballoon (CB2) is accepted as an effective and safe tool for pulmonary vein isolation (PVI). Although much more data exists about 1-year outcomes of CB2 ablation, data on long-term outcomes are scarce. Objective: We aimed to assess the long-term outcomes of PVI using CB2 in a large-scale symptomat...
Article
Full-text available
Background Cryoballoon (CB) ablation is a safe alternative to radiofrequency ablation in the treatment of atrial fibrillation (AF). However, phrenic nerve damage (PND) is a bothersome complication of the procedure. Purpose In this study, we aimed to establish the incidence of PND during CB and define the characteristics of affected patients. Meth...
Article
Despite technological advancements, radiofrequency catheter ablation for pulmonary vein isolation remains a challenging procedure, as maneuvering the catheter to obtain effective lesions is technically complex and time consuming. For this reason, balloon-based ablation systems have been developed, which can quickly and easily isolate the pulmonary...
Article
Full-text available
Background: Fragmented QRS (fQRS) on 12-lead electrocardiography is a noninvasive marker of intramyocardial conduction delay due to ventricular scarring that has not previously been studied in atrial fibrillation. Objective: The purpose of this study was to assess the association of fQRS with left atrial (LA) scarring in patients with persistent...
Article
Full-text available
Background: The electrocardiogram (ECG) is essential for the differential diagnosis of wide QRS complex tachycardia (WCT). Objective: To evaluate the diagnostic value of a novel ECG algorithm based on the morphologic characteristics of the QRS on the limb leads. Methods: Limb Leads Algorithm (LLA) was evaluated by analyzing 528 monomorphic WCT...
Article
Full-text available
Aims: Pulmonary vein isolation (PVI) alone in persistent atrial fibrillation (AF) is not as successful as in paroxysmal AF, and recent data indicate the key role of non-PV triggers. We aimed to assess the long-term safety and efficacy of left atrial appendage isolation (LAAi) as an adjunct to PVI using cryoballoon (CB) in persistent AF. Methods a...
Conference Paper
Background and Aims: Vitamin D has pleomorphic effects on the cardiovascular system and it is well known that vitamin D deficiency is related to atherosclerosis. Vitamin D deficiency is associated with coronary artery calcification. Vitamin D also plays a significant role in vascular calcification including breast artery calcification and aortic st...
Article
Full-text available
Background and Aims: Vitamin D has pleomorphic effects on the cardiovascular system and it is well known that vitamin D deficiency is related to atherosclerosis. Vitamin D deficiency is associated with coronary artery calcification. Vitamin D also plays a significant role in vascular calcification including breast artery calcification and aortic st...
Article
Full-text available
Background: Immediate hemostasis following removal of sheaths is essential to prevent access site complications after atrial fibrillation (AF) ablation. Despite various precautions to achieve complete hemostasis in a safe and effective manner, no standard approach is present yet. Objective: We aimed to compare the efficacy and safety of standard...
Article
Full-text available
Background: We evaluated the association of P wave duration (PWD) with LA scar in paroxysmal atrial fibrillation (PAF) patients. Methods: Consecutive PAF patients undergoing their first catheter ablation were screened and only those in sinus rhythm (SR) at baseline were included in the analysis. Standard 12-leads ECG was performed in all and 3D...
Conference Paper
Full-text available
Background Although cardiovascular (CV) diseases are very common in inflammatory arthritis like psoriatic arthritis (PsA), long-term impact of medication on CV outcomes is lacking. Objectives The aim of our study was to evaluate the long-term effects of anti-TNF-a drugs on subclinical atherosclerosis assessed by the flow-mediated dilatation (FMD)...
Article
Background Currently available second‐generation cryoballoon (CB2) is accepted as an effective and safe tool for pulmonary vein isolation (PVI). Although much more data exists about 1‐year outcomes of CB2 ablation, data on long‐term outcomes are scarce. Objective We aimed to assess the long‐term outcomes of PVI using CB2 in a large‐scale symptomat...
Article
Full-text available
The right atrial appendage (RAA) is a rare site of focal atrial tachycardia (AT). Sometimes, catheter ablation cannot successfully be accomplished at this location due to the difficulty in reaching the exact ablation site as well as the associated possible life-threatening complications like pericardial tamponade or perforation. Although radiofrequ...