Turhan Cağlar

• Dr. Zekai Tahir Burak Women's Health Research and Education Hospital

Background/Aim: This study aimed to evaluate perinatal outcomes in pregnancies complicated by absent end-diastolic flow (AEDV) in the umbilical artery. Methods: This retrospective cohort study was conducted at Etlik City Hospital Perinatology Clinic from November 2022 to June 2024. Eighty-five pregnant women diagnosed with AEDF in the umbilical art...

Background To investigate the effectiveness of maternal hemoglobin A1c (HbA1c) in the diagnosis of gestational diabetes mellitus (GDM) in the second trimester. Methods A total of 3000 pregnant women between 24 and 28 weeks of gestation were included in the study. Screening for gestational diabetes was performed using maternal HbA1c in 1200 pregnan...

Objective To determine the role of sortilin in the pathogenesis of preeclampsia by examining serum sortilin levels in maternal blood. Methods This prospective case-control study was conducted from May to November 2023 at the Perinatology Clinic of Ankara Etlik City Hospital. The study cohort was divided into two groups: Group 1 consisted of 44 pre...

Aims: The aim of this study was to investigate the impact of concordance and discordance in fetal sex on maternal, pregnancy, and neonatal outcomes in dichorionic twin pregnancies. Methods: This retrospective cohort analysis includes DCDA twin pregnancies delivered at Ankara Etlik City Hospital from January 2023 to December 2024. Pregnancies were c...

Aims: The primary aim of the study was to evaluate Doppler parameters focusing on fetal cerebral and placental circulation in gestational diabetes mellitus (GDM) and to investigate their relationship with maternal glycemic profiles. Methods: A prospective cohort study was conducted involving 52 pregnant women diagnosed with GDM and 55 control parti...

Objective The aim of this study was to investigate the relationship between placental abruption and maternal plasma calprotectin levels. Materials and methods This prospective study included 3865 pregnant women aged 24 weeks’ gestation and older who were admitted to Etlik Zübeyde Hanım Women’s Health Training and Research Hospital between January...

Background: Preeclampsia is a serious pregnancy complication known to be related to the pathophysiology of platelet dysfunction and inflammation. The aim of this study was to investigate the role of platelet indices and inflammatory markers in preeclampsia and their importance in predicting adverse neonatal outcomes. Methods: A total of 118 preecla...

Background/aim Epilepsy is one of the most common chronic neurological diseases. It can affect patients throughout their entire lives, including the reproductive years. It is estimated that epileptic women account for three to five births per 1000 births. Although the use of antiepileptic drugs (AEDs) during pregnancy has been associated with major...

Objectives: This study aimed to evaluate the relationships between maternal and neonatal outcomes and the Fibrosis-4 Index (FIB-4) and Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) in healthy pregnancies, late-onset preeclampsia (LOP), and early-onset preeclampsia (EOP). Methods: A retrospective study was conducted on 239 pregnant women...

Objectives: Maternal heart disease is a leading cause of non-obstetric maternal mortality and morbidity, complicating the necessary physiological changes during pregnancy. This study aimed to evaluate maternal and perinatal outcomes in pregnancies complicated by maternal heart disease. Methods: A retrospective analysis was conducted from November 2...

Aims: This study aimed to evaluate the perinatal outcomes of patients who underwent cervical cerclage and to investigate the relationship between these outcomes and systemic inflammatory indices. Methods: A retrospective study was conducted at Ankara Etlik City Hospital between November 2022 and November 2023. Patients were divided into three group...

Objectives As previous studies on the use of a cervical pessary to prevent preterm birth (PTB) have produced conflicting results, we aimed to investigate the feasibility, acceptability and safety of a new technique for inserting a cervical pessary and compare it with the traditional technique in patients at high risk of PTB. Methods Women at high...

Aims: This study aims to analyze the treatment approaches and reproductive outcomes of women diagnosed with cesarean scar pregnancy (CSP). Methods: A retrospective analysis was conducted on sixty patients diagnosed with CSP between January 2020 and December 2023 at two tertiary centers with a combined total of 49,733 births during the study period....

Background: The aim of this study was to investigate the impact of changes in diagnostic processes and criteria for gestational diabetes mellitus (GDM) on adverse obstetric outcomes associated with GDM. Methods: A total of 3000 pregnant women between 24 and 28 weeks of gestation were included in the study. Screening for gestational diabetes was per...

Problem This study aims to evaluate the effectiveness of inflammation indexes (systemic immune‐inflammation index [SII], systemic inflammation response index [SIRI], pan‐immune inflammation value [PIV], and neutrophil‐to‐lymphocyte ratio [NLR]) in the diagnosis of intrahepatic cholestasis of pregnancy (ICP). Method of Study A retrospective study w...

Aims: The aim of this study is to comprehensively evaluate the demographic, first-second trimester laboratory parameters and perinatal outcomes in pregnant women with epilepsy. Methods: The study had a total of 73 pregnant women with epilepsy, along with 149 healthy pregnant women. Demographic data, first-second trimester laboratory parameters, sei...

Background: The relationship between the pregnancy modified DIC score, which is applied in obstetric conditions where the risk of disseminated intravascular coagulation is high, and underlying disease, as well as its effect on the prognosis, was investigated. Methods: Those with a DIC score ≥ 26 from obstetric conditions, such as obstetric bleed...

OBJECTIVE: To evaluate maternal Resolvin D1 levels in women with gestational diabetes mellitus (GDM) and investigate the association between perinatal outcomes. STUDY DESIGN: This case-control study included 88 singleton pregnancies, conducted from August 2023 to January 2024, at a tertiary care center. Participants were divided into two groups: 44...

Objective To recalculate the estimated fetal weight (EFW) based on ultrasound measurements in patients complicated with isolated polyhydramnios, using 14 current formulas to observe which formula better predicts the EFW. Methods This study examined pregnant women who gave birth in the hospital between January 2015 and January 2020. Maximum vertica...

Objective: The aim of this study was to compare pregnancy outcomes of patients with polyhydramnios due to late-onset gestational diabetes mellitus and patients with isolated polyhydramnios. Methods: Of the women who fully participated in prenatal examinations at Etlik Lady Zübeyde Hospital between January 1, 2018, and December 31, 2019, women wi...

Aim: Progesterone metabolites are known to be elevated in the serum of patients with intrahepatic cholestasis of pregnancy (ICP), and exogenous progesterone supplementation in early pregnancy may cause an increase in progesterone metabolites. The aim of this study is to investigate the relationship between ICP and exogenous progesterone intake. Mat...

Introduction To determine a cut-off value for systemic immune-inflammation index (SII) (neutrophil × platelet/lymphocyte) in the prediction of fetal growth restriction (FGR). Materials and methods This case–control study was conducted retrospectively at the Obstetrics-Gynecology and Perinatology Clinics of Etlik Zubeyde Hanim Women’s Health Educat...

Purpose: We aimed to find out whether the systemic immune inflammatory index and the pan-immune inflammatory score can be used as markers for predicting continuation of pregnancy in the prediction of threatened abortion. Materials and Method: This case-control study was conducted retrospectively in the Obstetrics and Gynaecology Clinic of Ankara Et...

Objective: To analyze the ultrasonography (USG) values of median nerve cross sectional area (MN-CSA) in pregnant women with and without clinically diagnosed carpal tunnel syndrome (CTS). Design: Prospective cross-sectional study. Setting: Third trimester pregnant women during their routine office visits. Methods: USG was performed by a perinatologi...

Objective: The clinical significance of subchorionic hematoma, which is worrisome to pregnant women in terms of the outcome of the pregnancy, still remains unclear. The objective of this study is to examine the association between subchorionic hematomas in patients with threatened miscarriage and adverse pregnancy outcomes. Materials and Methods: T...

Objective: To determine factors affecting obstetric outcomes in pregnancies after conization by loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC) due to cervical intraepithelial neoplasia (CIN). Material and methods: The maternal and clinical characteristics and obstetric outcomes of CKC, LEEP and control groups were...

Objective: To predict preeclampsia by the ratio of the HCG MoM value in the first and second trimester screening tests. Material and Methods: The HCG-MoM values of 136 pregnant women with preeclampsia and 222 normatensive pregnant women used for first- and second-trimester screening tests were proportioned , and the difference between the groups wa...

Objective The aim of the present study is to compare the cavum septum pellucidi (CSP) z-score in euploid and aneuploid fetuses and to investigate the performance of the CSP width/length and CSP width/biparietal diameter (BPD) ratios as a diagnostic marker in aneuploidy. Methods A total of 54 patients, 20 aneuploid and 35 euploid fetuses, between 18...

Objective: Our work aims to determine whether there is an association between first-trimester serum pregnancy-associated plasma protein A (PAPP-A) multiples of the median (MoM) value and placenta previa with or without placenta accreta spectrum disorders (PAS) in women. Patients and methods: A retrospective analysis was performed on 267 patients...

Introduction; To determine a cut-off value for systemic immune-inflammation index (SII) (neutrophil × platelet /lymphocyte) in the prediction of fetal growth restriction (FGR). Materials – Method; This retrospective case control study was designed at the Obstetrics - Gynecology and Perinatology Clinics. Singleton pregnant women with late onset FGR...

Objectives: Investigating the relationship between liver enzymes, uric acid (UA), and macrosomia will benefit physicians in the early detection of complications that may emerge during/after pregnancy. The study analyzed liver enzyme activity and UA levels in first-trimester pregnant for the risk of macrosomia. Methods: This retrospective cross-s...

This study aimed to compare fetal myocardial performance index (MPI) between fetuses of pregnant women with gestational diabetes mellitus (GDM) and healthy controls and to evaluate the relationship between MPI and maternal glucose levels. This was a prospective study of 90 pregnant women, including 50 pregnancies with GDM (27 pregnancies with insul...

Objective: In this study, we aimed to compare the measurements of some fetal cranial structures and Doppler parameters between the groups with congenital heart disease and healthy pregnant women. Materials and Methods: The study included 30 patients with intrauterine congenital heart disease and 30 healthy pregnant women. Fetuses with additional st...

OBJECTIVE: We aimed to determine the effect of uterine leiomyoma characteristics and cesarean myomectomy on maternal and perinatal outcomes. STUDY DESIGN: The study included patients with singleton pregnancies and uterine leiomyomas who had delivered at or beyond 24 weeks' gestation; without comorbidities, uterine anomalies, or fetal malformations....

Aim: Twin pregnancies are associated with increased perinatal mortality and morbidity compared with singleton pregnancies. Single intrauterine fetal death (sIUFD) is difficult to treat. This is because the twin who survives after sIUFD is at high risk for mortality, neurological damage, and other complications of preterm birth. Therefore, in this s...

Background: Sestrin-2 (SESN2) is a antioxidant protein that can be activated by a number of conditions, including DNA damage and hypoxia. Aims: Our objective was to evaluate maternal serum SESN2 levels in patients with intrauterine growth restriction (IUGR) and its association with adverse perinatal outcomes. Methods: This prospective study in...

Aims: High bisphenol A (BPA) concentration may compromise normal placental development. The aim of this study was to determine maternal serum BPA concentrations in pregnant women with complicated preeclampsia (PE) and normal pregnant women, to compare BPA concentrations, and to examine pregnancy outcomes. Methods: This prospective case-control s...

Objective Placenta previa is one of the causes of neonatal anemia. This condition is mainly explained by antenatal hemorrhage and incision of the anteriorly located placenta during cesarean section. However, the mechanism of neonatal anemia in placenta previa has not been extensively studied or well elucidated. This study investigates whether place...

Aim: This study aimed to investigate the utility of inflammatory indices in predicting adverse maternal and neonatal outcomes in pregnant women with recurrent urinary tract infections. Material and Methods: This retrospective study was conducted on pregnant women treated for symptomatic urinary tract infection (UTI) between 2017 and 2021. Pregnant...

Objective: To study the value of fetal epicardial fat thickness (EFT) in gestational diabetes mellitus in the third trimester of pregnancy and its relationship with clinical parameters and perinatal outcomes. Methods: A total of 80 participants, including 40 with diagnosed GDM and 40 healthy pregnant women, were included in the study. Demographi...

Postpartum hemorrhage is the most important and also preventable cause of maternal morbidity and mortality worldwide. Arteriovenous malformation (AVM) is a rare cause of postpartum hemorrhage. We present a case of arteriovenous malformation, which may be one of the rare but potentially fatal causes of postpartum hemorrhage (PPH). In the case report...

Aim: To investigate the risk factors and outcomes of emergency intervention in pregnant women with placenta previa (PP). Material and method: This retrospective study was conducted between June 2015 and January 2021. Pregnant women with PP were divided into emergency and planned intervention groups according to surgical planning. The groups were co...

Objective (s): To compare the presence and severity of striae gravidarum in pregnant women with and without stress urinary incontinence and to evaluate whether there is a relationship between the severity of striae gravidarum and the severity of incontinence in pregnant women with stress urinary incontinence. Study Design: Healthy primigravid pregn...

Objective: To study the value of fetal epicardial fat thickness (EFT) in gestational diabetes mellitus in the third trimester of pregnancy and its relationship with clinical parameters and perinatal outcomes. Methods: A total of 80 participants, including 40 with diagnosed GDM and 40 healthy pregnant women, were included in the study. Demographic d...

Objectives: This study is intended to determine the relations between indications of prenatal diagnostic testing and fetal chromosomal abnormalities and evaluate the complications of invasive diagnostic tests. Methods: Indications, results from karyotyping and complications were evaluated in pregnant women who preferred invasive diagnostic testing...

Objective: We aimed to determine whether follow-up in the intensive care unit for the postoperative first 8 hours is beneficial for early intervention in postpartum hemorrhage. Material and methods: In our hospital, all patients are admitted to the intensive care unit for the first 8 hours after cesarean section. Patients with postpartum hemorrh...

Confirmation of carpal tunnel syndrome (CTS) diagnosis with sonographic measurement of the median nerve cross sectional area (MN-CSA) is increasing in popularity. We aimed to analyse the ultrasonography (USG) values of MN-CSA in pregnant women with and without CTS symptoms. MN-CSAs of third trimester pregnant women were measured with USG and they w...

Objective: The new adipokine, neuregulin-4 (NRG-4), acts as a signaling protein and plays a role in lipogenesis, inflammatory events and atherosclerosis. The aim was to investigate maternal levels of NRG-4 in preeclampsia (PE) disease. Material and methods: Pregnant women with PE, divided into severe and mild PE, and gestational age-matched heal...

The aim of this study was to evaluate the maternal–fetal and neonatal outcomes in cases with thyroid autoantibody (anti-thyroglobulin [TG] and anti-thyroid peroxidase [TPO]) determined as positive during pregnancy. The study included 46 pregnant women (n = 11 and n = 35, respectively) with high results in thyroid autoantibody screening. The groups...

Background Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by persistently elevated platelet count without a clear secondary cause. Although most patients with ET are between 55 and 60 years of age, it has been estimated that 20% of women with ET are diagnosed during reproductive ages. Miscarriage is the most f...

Objective To investigate the associated anomalies and outcomes of fetuses diagnosed as having a single umbilical artery (SUA) which were reported inconsistently in previous studies. Methods The data of 82 pregnancies with fetal SUA, 35 of which were complex, and 47 isolated SUA (iSUA) and 100 pregnancies with fetal double umbilical arteries (DUA) b...

Objective The present study is intended to investigate the causes of stillbirth and its relationship with maternal conditions using the International Classification of Diseases-Perinatal Mortality (ICD-PM) system. Material and Methods All early and late fetal deaths between 2015 and 2020 were analyzed. Time of death, fetal causes, and the maternal...

Objective The purpose of this study is to evaluate antioxidant balance in pregnant women with meconium-stained amniotic fluid. Methods Forty pregnant women with meconium-stained amniotic fluid and 40 pregnant women with non-meconium-stained amniotic fluid were included in the study. By checking the ischemia modified albumin (IMA) level and thiol/d...

Objective: To evaluate the risk factors, chromosomal abnormalities and additional anomalies of cases diagnosed with fetal neural tube defects (NTDs). Material and Method: The data of cases diagnosed with fetal NTDs between January 2016 and August 2020 with fetal NTD were retrieved from the hospital database. Only patients whose diagnosis confirmed...

Amaç: Çalışmamızda intrauterin fetal ölüm nedeniyle ölü doğum gerçekleştirmiş gebe kadınlara ait antenatal tarama testi parametrelerinin retrospektif incelenerek maternal yaş ve doğum haftalarına göre fetal ölüm üzerine olan prediktivitesinin değerlendirilmesi amaçlandı. Gereç ve yöntemler: Bu retrospektif kohort çalışmaya, 1 Ocak 2017-15 Haziran 2...

Introduction: We investigated the effect of epilepsy on cord blood oxidative stress status. Material and methods: Thirty (n = 30) pregnant women with epilepsy and thirty (n = 30) healthy controls enrolled in this case control study. Albumin and IMA values and dynamic thiol/disulfide parameters were measured. Results: Decreased native thiol and...

Aim: This study aimed to investigate maternal serum levels of calprotectin in patients with intrahepatic cholestasis of pregnancy (ICP) and to compare these with serum calprotectin levels in healthy pregnant women. Methods: Ninety pregnant women (ICP group, n = 45; healthy control group, n = 45) were included in the study. The gestational age an...

Objective First trimester thyroid-stimulating hormone (TSH) level is an important determiner of neonatal outcome. In this study we investigated the relationship between first-trimester TSH level and fetal birthweight. Materials-Methods: First-trimester serum TSH, age, gravidity, parity, body mass index (BMI), gestational age, and birth weight were...

Purpose We aimed to analyze the linear changes of Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Systemic Immune-Inflammation Index (SII) levels in pregnant women who administrated magnesium sulfate for fetal neuroprotection. Methods This retrospective study included 63 pregnant women who underwent neuroprotective mag...

Objective Growth differentiation factor-15 (GDF-15), the new member of transforming growth factor (TGF)-beta family, is released as a response of oxidative stress, inflammation and tissue injury. We aimed to determine GDF-15 levels in patients with Gestational Diabetes Mellitus (GDM) and the relation between GDF-15 and adverse perinatal outcomes....

Objective To measure serum levels of podocalyxin (PODXL) in recurrent miscarriages as a marker of vascular endothelial dysfunction. Study design In this case-control study, women who were hospitalized for singleton first-trimester pregnancy terminations due to missed abortion, anembryonic pregnancy, and inevitable abortion were included. There wer...

Proboscis lateralis is a very rare congenital craniofacial malformation characterized by a finger-like tubular appendage arising usually from the medial canthal region. It is mostly unilateral and associated with other craniofacial malformations. Occasionally, proboscis lateralis is seen with holoprosencephaly. A rare case of bilateral proboscis la...

To evaluate the relationship between the actual maternal serum alpha-fetoprotein (MSAFP) levels and maternal, fetal, and neonatal outcomes in patients diagnosed with placental abruption. This prospective case-control study included 40 patients who presented at the Perinatology Department between December 15, 2018, and September 01, 2019, were diagn...

Objective: To determine whether the ratio of the first-trimester aspartate aminotransferase (AST) to platelet ratio index (APRI) score will be useful as a new determinant of hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome that may develop in the later stages of pregnancy Study Design: Descriptive-analytical study. Place and dura...

Purpose Thyroid hormones and antibodies are known to participate in angiogenesis and invasion and also thyroid hormone receptors are expressed in the placenta. We aimed to evaluate the relationship of serum levels of thyroid-stimulating hormone (TSH), thyroid hormones (TH), and anti-thyroid antibodies with abnormally invasive placenta (AIP). We als...

Objective Congenital infections in refugee women have been very rarely studied. The purpose of this study is to investigate the Toxoplasma gondii (T. gondii) seroprevalence in Syrian pregnant refugee women living in Turkey and to discuss the differences with Turkish pregnant women. Study Design This is a retrospective cohort study including 752 pr...

Objective To evaluate the predictive value of the first-trimester aspartate aminotransferase (AST)/platelet count ratio [AST to platelet ratio index (APRI) score] for intrahepatic cholestasis in pregnancy (ICP). Methods This study consisted of a patient group diagnosed with ICP (n = 37) and a control group (n = 66) who presented to the hospital pe...

Objective: To investigate the association between maternal serum neutrophil-to-lymphocyte ratios (NLRs) and pregnancy outcomes in women with familial mediterranean fever (FMF). Background: FMF exists worldwide, it primarily affects Mediterranean countries METHODS: We retrospectively analysed data from 269 pregnant women, who underwent a routine...

Objective We aimed to analyse the pre‐analytical process and its effect of 50 g of oral glucose challenge test results for screening gestational diabetes mellitus. Research Design and Methods The 50 g oral glucose challenge test was performed to 30 pregnant women, and the blood was collected as two samples for three tubes containing; serum separat...

Objective: This study aims at assessing the effectiveness of various treatment protocols with the help of some parameters in caesarean scar pregnancies. Methods: A total of 26 patients were assessed in the study. The patients were divided into 4 groups. Group 1 consisted of those who had a wedge resection (n = 7), group 2 those who had a suction...

Aim: This study aimed to investigate the potential increase in the pregnancy complications during the pandemic period. Materials and Methods: Data of the pregnant women who were admitted between April/May2019 and April/May2020 for stillbirth, preterm labor, term prelabor rupture of membranes (PROM), preterm premature rupture of membranes (PPROM), p...

: Thrombocytopenia is defined as a platelet count less than 150 000/μl and it is the most common hematologic disease after anemia in pregnancy. This study aims to investigate pregnant women with severe thrombocytopenia (platelet count <50 000/μl). In the relevant literature, few studies have addressed severe thrombocytopenia in pregnancy. This is a...

Amaç: Tersiyer referans hastanemizde, sonografik olarak ilk trimesterde subkoryonik hematom (SKH) bulgusu izlenen ve SKH bulgusu olmayan abortus imminens tanılı hastaların gebelik sonuçlarının karşılaştırılması amaçlandı. Materyal ve Metod: Bu retrospektif kohort çalışmada Dr. Zekai Tahir Burak Hastanesi’nde 2017 ve 2018 yıllarında abortus imminens...

Amaç: Preterm erken membran rüptüründe (PPROM) ve preterm doğumda (PD) idrar yolu enfeksiyonunun olumsuz neonatal sonuçları ve doğum süresine ile arasındaki ilişkinin araştırılmasını amaçladık.Gereç ve Yöntem: 2008-2014 yılları arasında merkezimize başvuran 1033 gebe hastayı retrospektif olarak değerlendirdik. Çalışma grupları 446 PPROM ve 587 PD h...

Komplet tip mol hidatiform ve canlı fetusun birlikte bulunduğu ikiz gebelik klinikte oldukça nadir rastlanılan obstetrik bir durumdur. Tanı sonrası gebeliğin yönetimi oluşabilecek maternal ve fetal komplikasyonlar nedeniyle tartışmalıdır ve pratikte ikilem yaratır. Literatürde gebelik terminasyonunu destekleyen yayınlar bulunmakla birlikte son yıll...

Aim: We investigated maternal copeptin level's usefulness in prediction of preterm birth. Materials and methods: The study was comprised of 97 pregnant women hospitalized for threatened preterm labor and 35 healthy pregnant women without preterm labor. Serum copeptin were compared with likelihood of threatened preterm labor timing of delivery and...

Objective: We summarized our five-year chorionic villus sampling (CVS) experience with indications, detected chromosomal abnormalities and pregnancy outcomes. Materials and Methods: This retrospective study examined 552 patients underwent CVS for prenatal diagnosis between 2014 and 2018. Results: The most frequent patients undergoing CVS indicatio...

Purpose: IL-33 is associated with invasion, proliferation, and metastasis of various cancers. The trophoblastic cells of placenta previa accreta (PPA) invade into the myometrium in a similar way to the invasion of cancers. We studied the role of IL-33 in PPA and also aimed to investigate its relation with adverse maternal outcome in this placental...

Fibular hemimelia (FH) is a congenital deficiency in which a part or all of the fibular bone is hypoplastic or aplastic and associated with hypoplastic tibia and foot anomalies. The main differential diagnoses include proximal focal femoral dysplasia, Femur-Fibula-Ulna syndrome, and Femoral Hypoplasia-Unusual Facies syndrome. Proximal focal femoral...

Context: We aimed to examine the factors affecting adverse gestational outcome in gestational diabetes (GDM) patients, who were grouped as obese and normal- weight, having only-diet, or insulin treatments. Subjects and methods: The study included 373 patients, treated with diet or insulin. These patients were sub-grouped as obese and non-obese,...

We aimed to determine the role of placental A Disintegrin and Metalloproteinase with thrombospondin motifs 5 (ADAMTS5), and maternal serum ADAMTS5, total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) levels at 24–28th gestational weeks in GDM. This study included 57 patients, who had been diagnosed as having...

Aim: The main aim of this study was to investigate thiol/disulfide homeostasis associated with fetal growth restriction (FGR) and to evaluate whether alterations are predictive for adverse neonatal outcomes. Methods: 273 pregnant women (77 with FGR and 196 with normal fetal growth) were enrolled in this prospective case–control study. Results: Nati...

Objective: To evaluate the obstetric outcomes of fetuses with cystic hygroma other than karyotype abnormalities and structural malformations. Material and methods: We conducted a retrospective study based on the review of medical records of pregnant women in whom ultrasonographic diagnosis of fetal cystic hygroma was established in the first tri...

Objective(s) To investigate the association between striae gravidarum and low back pain in pregnancy. Study Design 200 healthy pregnant women with first, uncomplicated and singleton pregnancy at a gestation age of 36–37 weeks were evaluated for striae gravidarum Davey score. Back pain was assessed by Visual Analogue Scale and functional disability...

Twin-twin transfusion syndrome (TTTS) and recently discovered twin anemia-polycythemia sequence (TAPS) are well-known severe complications of monochorionic pregnancies which are associated with placental anastomoses. TAPS may occur spontaneously with a prevalence of 3% to 5% in monochorionic pregnancies. It also can occur iatrogenically after laser...

Background/aim: The main aim of this study was to investigate serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and arylesterase levels in pregnant women with placenta accreta and to compare those with age-matched healthy pregnant women. Materials and methods: A total of 27 pregnant women who had clinic...

Aim: The aim of our study is to compare serum thiol/dilsulphide homesostasis of women diagnosed with abortus imminens (AI) and healthy pregnant women, and to determine whether it has a role in the pathogenesis of the disease or not. Materials and methods: A total of 100 pregnant women were included in the study. The study group consisted of 50 pati...

Krukenberg tumor refers to gastrointestinal cancer metastatic to the ovaries, and has an extremely poor prognosis, with a five-year survival rate ranging from 12% to 23.4%. Gastric cancer has been reported as the most frequent primary source of Krukenberg tumor; however, tumors of the colon, appendix, breast, lung, and pancreas have also been repor...

It is thought that abnormal invasive implantation of the placenta occur as a result of the defect came decidua basalis only in women who have a history of cesarean section previously. Massive obstetric hemorrhage has increased in placenta accreta. Despite the ultrasound, doopler ultrasound and magnetic resonance, in early pregnancy weeks the diagno...

Morbidly adherent placenta (MAP) is a growing concern currently and is still a diagnostic challenge for obstetricians. As emergency hysterectomy due to unscheduled delivery in MAP carries significant risks, we aimed to evaluate whether first and second trimester serum analytes may be used in the prediction of MAP requiring hysterectomy. A retrospec...

Uterine leiomyomas are the most common benign tumor of the female reproductive tract. Their incidence during pregnancy is approximately 2 percent and they are associated with some complications such as preterm labor, placental abruption, fetal malpresentation, obstructed labor, cesarean delivery, and postpartum hemorrhage. They may develop anywhere...

Objectives: TNF-related apoptosis-inducing ligand receptor-2 (TRAIL-R2) is produced both by decidual and trophoblast cells during pregnancy and known to participate in apoptosis. In this study, we aimed to determine and to compare maternal serum and placental TRAIL-R2 levels in patients with placenta accreta, non-adherent placenta previa and in he...