Tülay Becerir

Tülay Becerir
Pamukkale University · Department of Pediatrics

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31
Publications
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75
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Publications

Publications (31)
Article
Full-text available
Background Drug-induced nephrotoxicity is an important side effect of many commonly used drugs. In this study, we planned to evaluate the effects of teneligliptin (TG), which is a dipeptidyl peptidase-4 (DPP-4) inhibitor, on cell healing by creating nephrotoxicity models in human renal proximal tubule cell and human embryonic kidney epithelial cell...
Article
Full-text available
Background Although acute coronary syndrome is rare in children, it is the most important cause of mortality in children with end-stage renal disease. Case presentation Here, a 16-year-old pediatric patient, who has been on dialysis since the age of 3, and who was diagnosed with acute coronary syndrome and placed an emergency percutaneous transcat...
Article
Objective: By creating nephrotoxicity models with cisplatin, vancomycin, and gentamicin in HK-2 (human renal proximal tubule cell) and HEK293T (human embryonic kidney epithelial cells) cell lines, we aimed to evaluate the effect of cilastatin on recovery of cell damage after toxicity had occurred. Materials and methods: In the first phase of the...
Chapter
Vezikoüreteral reflü (VÜR), idrarın mesaneden üreterler ve böbreklere doğru geri akımı olarak tanımlanır. Çocukluk çağının en sık görülen konjenital ano-malilerinden biridir. Böbrek hasarına neden olması ve çocukluk çağı kronik böbrek yetmezliğinin etyolojik nedenleri arasında ilk sırada yer alması nedeniyle de önemlidir. 1 Ülkemizde 2009 yılında y...
Chapter
Sistemik lupus eritematozus (SLE), birden fazla organı etkileyebilen yaygın infla-masyon ile karakterize, immün kompleks aracılı kronik bir hastalıktır. SLE pre-valansı 100.000 kişide 70 ile 90 olarak bildirilmiştir. Erişkin SLE vakalarının % 20'si adelösan dönemde tanı almaktadır. 1,2 SLE'li çocukların %50-60' ının Lupus nef-riti (LN) geliştirdiği...
Article
Subcutaneous fat necrosis (SFN) in the newborn is a form of panniculitis which presents with erythematous nodules and indurated plaques. Severe life-threatening hypercalcaemia can occur as a late complication. A 2-month-old girl presented with severe hypercalcaemia and acute renal injury as a complication of SFN. She was admitted to hospital with t...
Article
Cardiac involvement is very rare in patients with Henoch-Schönlein purpura (HSP). In this case study, we present an 8-year-old girl presenting with HSP-induced myocarditis and thrombus in the right atrium and HSP nephritis. To date, 15 cases of HSP-related cardiac involvement have been reported in the PubMed/MEDLINE, Scopus, and Google Scholar data...
Article
Objective: Pediatric urolithiasis is a globally growing problem. The composition and frequency of urinary tract stones vary not only among different countries, but across various regions in a country. Hence, we aimed to identify the types and frequencies of urinary tract stones in children from our region (Inner Western Anatolian part of Turkey),...
Article
Full-text available
Purpose Acute pyelonephritis is associated with considerable morbidity and potential for renal scarring. Pentraxin3 (PTX3) is a recently discovered mediator of inflammation. The objective of this study was to investigate the changes in serum and urine PTX3 levels in children who had a history of pyelonephritis and were diagnosed with renal parenchy...
Article
IntroductionStudies relating to first-line, early, and long-term eculizumab treatment and outcomes in children with atypical hemolytic uremic syndrome (aHUS) are scarce and unclear. The aim of this case-series study was to evaluate the outcomes of first-line, early, and long-term eculizumab treatment in our aHUS patients. Materials and Methods We r...
Article
Objective: To evaluate trends in the prevalence of symptoms and risk factors of atopic eczema in 13-14 years old school children in Denizli. Material and Methods: This survey was first conducted in 2002 and repeated in 2008 using the same ISAAC questionnaire in the same age group. Possible risk factors were also asked. Results: A total of 3004 chil...
Article
Full-text available
The aim of this study was to evaluate the potential of serum pentraxin 3 (PTX3) values as an early predictor of subsequent renal involvement in patients with Henoch-Schönlein purpura (HSP) with no abnormalities on urinary examination and in renal function tests at disease onset. This was a prospective cohort study which included 60 pediatric patien...
Article
Full-text available
Background: This study was performed to evaluate the time trends in prevalence of asthma and related factors in Denizli, Turkey. Methods: Two cross-sectional surveys were performed, 6 years apart (2002 and 2008) using the ISAAC protocol, in the 13-14 age groups and comparisons were made between the results. Results: Lifetime prevalence of whee...
Article
There is currently no standard tool for the measurement of asthma in epidemiological studies. The objectives of this study were to determine the prevalence of asthma, to describe the potential local risk factors, and to assess the agreement between written and video questionnaires in 13- to 14-year-old schoolchildren. We performed a cross-sectional...
Article
Objective To investigate the demographic characteristics, clinical features, and metabolic risk factors of children with urolithiasis. Methods This retrospective study enrolled 52 boys, 51 girls with urolithiasis diagnosed by ultrasonography. Mean age at presentation was 60(1–192) months, and mean follow-up period was 5.5 (1–27)months. Results The...
Article
Objective The aim of this study was to determine the risk factors such as age, sex, duration of fever, voiding dysfunction, constipation, history of recurrent UTI, the levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC), polymorphonuclear leukocytes (PNL), platelet count, mean platelet volume (MPV), seru...

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