Tuan Anh Le

Vietnam Academy of Science and Technology | VAST · Mien Trung Institute for Scientific Research

To contribute to further research on the biodiversity value of Song Dam lake, aiming to preserve the wetland area of Quang Nam province, the research team conducted a diverse investigation of its components. Species and use value of higher vascular plants in Song Dam lake area. The study uses field survey methods to collect samples; Analyze samples...

The paper presents new data on the orchid diversity of Vietnam obtained mainly during the fieldwork of 2023–2024, as well as a result of investigation of the herbarium and garden collections of Russia and Vietnam. It includes five species new to science, namely Cleisostoma truongquanii, Cymbidium bavuongii, Hemipilia uniflora, Micropera vietnamensi...

Begonia triquetra, a new species endemic to the limestone karst regions of Son La province in Northwestern Vietnam, is described and illustrated here. This new species resembles B. xenos in its suberect habit, subpeltate lamina, 4-tepaled staminate flowers, and 2-locular ovary. However, B. triquetra differs significantly from B. xenos in having tri...

Objective: This study aims to investigate the chemical constituents and biological properties of the essential oil derived from Psychotria laui, a plant recognized for its medicinal applications, particularly in traditional Vietnamese medicine, where it is utilized for the treatment of digestive and inflammatory disorders. Methods: Fresh leaves of...

Three new spirostan glycosides, dracochinosides A-C (1-3), and four known steroidal glycosides (4-7) were isolated from the aerial parts of Dracaena cochinchinensis (Lour.) S.C.Chen. Their chemical structures were determined by the IR, HR-ESI-MS, 1D-, and 2D-NMR spectra. Compounds 1-3, 6 and 7 inhibited nitric oxide production in LPS activated RAW...

Mitreola sphaerocarpa (Loganiaceae), a species occurring in Peninsular Malaysia, is newly reported for the flora of Vietnam. The description, photographs, information on ecology, preliminary conservation status and taxonomic notes are also presented. In order to facilitate identification, we provide an identification key and checklist for the 4 kno...

The paper presents new data on the orchid diversity of Vietnam obtained mainly during the fieldwork of 2020–2023, as well as a result of investigation of the herbarium collections of Russia and Vietnam. It includes two species new to science, Bidoupia micrantha and Hylophila vietnamensis, and three species new to the native flora of Vietnam, i.e. D...

Phytochemical study on the methanol extract of the leaves of Phyllanthus reticulatus led to the isolation of two new compounds, phyllanreticosides A (1) and B (2) together with ten known ones (3‐12). Their chemical structures were determined by HR‐ESI‐MS, NMR, and ECD spectra in comparison with the literature. Three ellagitannins, phyllanreticoside...

Gnetum formosum Markgr., a member of the Gnetaceae family, is distributed in Vietnam. This plant remains a botanical enigma with an unexplored diversity of chemical constituents and pharmacological effects. In this study, two new steroidal saponins, namely gnetumosides A (1) and B (2), were isolated from the aerial parts of G. formosum. Their chemi...

The study was conducted to assess the diversity of flowering plants (Magnoliophyta) in Gao Giong ecotourism area, Cao Lanh district, Dong Thap provine, through field surveys and plant sampling collection in typical habitats. The results recorded 89 families, 249 genera and 337 species. Taxa belonging to Magnoliopsida (Dicotyledonae) are more divers...

Anaxagorea luzonensis A. Gray, a member of the Annonaceae family, has been used to treat a variety of illnesses for a long time. For the first time, A. luzonensis volatile compounds (ALVCs) were extracted from the leaves, and the components were identified using gas chromatography-mass spectrometry (GC-MS). Further, the main compositions of ALVCs w...

A new species of Glycosmis (Rutaceae), G. quangtriensis is described based on the specimens collected from the Limestone Razorback Hill and Rockpile Hill, in Huong Hiep Commune, Dakrong District and Cam Tuyen Commune, Cam Lo District, Quang Tri Province, central Vietnam. Morphological description, photographs, a distribution map, vernacular name, a...

One new compound, styrene dimer-type listeanol-4-O-α-ʟ-rhamnopyranosyl-(1→4)-β-ᴅ-glucopyranoside (1), and four known compounds namely listeanol (2), isorhapotigenin (3), genetifolin E (4), gnetifolin K (5) were isolated from the methanolic extract from the aerial part of the Gnetum montanum Markgr. in Viet Nam. Their chemical structures were determ...

Objective: The ultimate objective of this study was to isolate bioactive compounds from Grewia bulot Gagn. leaves and evaluate their cytotoxicity against a panel of human cancer cell lines. Methods: Compounds were isolated by column chromatography, whereas their chemical structures were elucidated by NMR spectroscopic data, and literature compariso...

Objectives: This study aims to evaluate the cytotoxicity of compounds isolated from Buxus latistyla Gagnep. against selected cell lines. Methods: The isolation process was carried out using combined chromatographic techniques. The structural elucidation of compounds was achieved by combining 1D-/2D-NMR and HRESIMS data. The absolute configurations...

Begonia dakrongensis (Begoniaceae), a new species from Dakrong Nature Reserve, Quang Tri province in Central Vietnam

Background and aims – Vietnam is one of the leading diversity centres for Asian Malpighiaceae, comprising 24 accepted species and three native genera (i.e. Aspidopterys, Hiptage, and Tristellateia). During recent fieldwork towards completing the taxonomic revision of Malpighiaceae for the Flora of Vietnam, we have collected specimens from two popul...

This study is focused on investigating the chemical composition and bioactive properties of the essential oil extracted from Psychotria asiatica L., a plant species known for its medicinal properties. Utilising gas chromatography-mass spectrometry (GC-MS) analysis, the essential oil from P. asiatica was found to contain 53 distinct constituents. Ma...

Eight compounds, including 20( R )‐ginsenoside Rg 3 ( 1 ), Ginsenoside Rd ( 2 ), ginsenosides Rg 2 ( 3 ), ginsenosides Re ( 4 ), β ‐sitosterol ( 5 ), daucosterol ( 6 ), stigmasterol ( 7 ), and stigmasterol‐3‐ O ‐β‐glucoside ( 8 ) were isolated from the Panax ginseng sprouts cultivated in Vietnam. Their structures were elucidated by ¹ H, ¹³ C NMR, a...

The Hatinh langur (Trachypithecus hatinhensis) is an endangered and a restricted range species, found in northern central Vietnam and eastern Laos. The known distribution of the Hatinh langurs in Vietnam extends along the border with Laos from 18 o N, roughly on the border between Hatinh and Quang Binh Provinces, southwards to about 16 o 50' in the...

Objective: This study aimed to analyze the essential oil obtained from Litsea balansae Lecomte leaves and investigate its potential as an anti-inflammatory and antioxidant agent. Methods: Fresh L balansae leaves were collected in Quangtri, Vietnam, and subjected to hydro-distillation using a Clevenger-type apparatus to extract the essential oil. Th...

This study focused on the chemical composition and biological activities of the essential oil derived from Grewia bulot, a plant species known for its medicinal properties. The analysis of Grewia bulot essential oil revealed the presence of 78 constituents. The major compounds were α-cadinol (13.5%), 1,8-cineole (12.7%), 1,10-di-epi-cubenol (9.8%),...

Alkaloids are among the most important and best-known secondary metabolites as sources of new drugs from medicinal plants and marine organisms. A phytochemical investigation of the whole plant of Crinum asiaticum var. sinicum resulted in the isolation of seven alkaloids (1–7), including one new dimeric compound, bis-(-)-8-demethylmaritidine (1). Th...

TÓM TẮT Chi Sa nhân (Amomum) là một trong những chi lớn nhất của họ Gừng (Zingiberaceae). Kết quả điều tra, thu mẫu các loài thuộc chi Sa nhân trên 24 tuyến điều tra ở Khu bảo tồn (KBT) Sao La, tỉnh Thừa Thiên Huế đã xác định và định danh được 9 loài, bổ sung 4 loài cho danh lục thực vật Khu bảo tồn Sao La. Đặc điểm hình thái chính dễ nhận diện của...

A synopsis of the orchid genus Didymoplexiella is presented for Cambodia, Laos and Vietnam. Uncertainties in morphological delimitation of the species of Didymoplexiella are addressed in the context of the new data on variation of labellum structure; re-identification of a considerable number of specimens is performed in accordance with the current...

This research aims to determine the volatile compounds present in Grewia bulot leaf extracts and evaluate their cytotoxic and antioxidant activities. The volatile constituents of the n-hexane and dichloromethane extracts were identified by using gas chromatography–mass spectrometry. The main compounds identified in the former were neophytadiene (18...

Four undescribed phenolic glycosides including three stilbene derivatives (1 and 3) and sodium salt of 3 (2), and a chalcone glycoside (4), together with thirteen known compounds (5-17) were isolated from the leaves of Syzygium attopeuense (Gagnep.) Merr. & L.M.Perry. Their chemical structures were elucidated to be (Z)-gaylussacin (1), 6''-O-galloy...

Phytochemical study on the methanol extract of Aglaia odorata leaves resulted in the isolation of four previously undescribed compounds, including three 2,9-deoxyflavonoids and one flavonol-diamide [3 + 2] adduct, and 13 known compounds. The chemical structures of the four undescribed compounds were elucidated on the basis of their IR, HR-ESI-MS, 1...

The present study provides the first information on the chemical composition and acetylcholinesterase inhibitory activity of the essential oil (EO) from the leaves of Mitrephora poilanei Weeras. & R.M.K.Saunders from Vietnam. Gas chromatography and gas chromatography-mass spectrometry analysis revealed that the main components of the M. poilanei EO...

Three undescribed triterpene glycosides syzybullosides A-C (1-3) along with fourteen known compounds were isolated from the leaves of Syzygium bullockii (Hance) Merr.& L.M. Perry, including six triterpene glycosides (1-6), four phenolics (7-9, 17), four megastigmanes (10-13), and three flavonoids (14-16). The structures of 1-17 were elucidated by e...

Annonaceae is a large family, distributed mainly in tropical and subtropical low mountains. The results of the survey and collection of samples on 21 transects in Sao La Nature Reserve, Thua Thien Hue province from December 2021 to December 2022 have identified 35 species belonging to 13 genera, of which 1 genus and 9 species are added to the List...

Solanum melongena is a member of Solanum genus that widely cultivated as fruit vegetable in Vietnam. According to Vietnamese traditional medicine, the fruits and whole plants are used to treat toothache, turgescence, pruritus, and haemorrhoids. As part of our project to study the chemical composition and bioactivity of Solanum genus in Vietnam, fiv...

Four Rubiaceous species viz. Hedyotis diversifolia, Involucrella lithophila, Mouretia larsenii, Ophiorrhiza cana are newly recorded for the flora of Vietnam. Morphology based identification key, taxonomic notes, and photo-plates of the newly reported species are provided. Moreover, the second-step lectotype has been designated for the name Involucr...

Aspidistra phongdiensis is described based on the specimen collected from the Thua Thien Hue province of Vietnam. The new species is morphologically similar to A. khangii but differs in wider leaf blade (vs. narrowly elliptic), perigone white outside (vs. purple mottled), yellow pollen (vs. white), introrse anthers (vs. latrorse) and widely obconic...

A new species of Hedyotis L. (Rubiaceae), Hedyotis konhanungensis B.H. Quang, T.A. Le, K.S. Nguyen & Neupane, is described and illustrated from the central highlands of Vietnam based on morphological and phylogenetic evidence. The new species belongs to the morphologically diverse tribe Spermacoceae (ca. 1000 species) of the family Rubiaceae, which...

A new isopropyl chromone (1) and a new flavanone glucoside (2) together with eleven known compounds (3–13) were isolated from the leaves of Syzygium cerasiforme (Blume) Merr. & L.M.Perry. Their structures were elucidated as 5,7‐dihydroxy‐2‐isopropyl‐6,8‐dimethyl‐4H‐chromen‐4‐one (1), 5,7‐dihydroxyflavanone 7‐O‐β‐D‐(6′′‐O‐galloylglucopyranoside) (2)...

Essential oils of the leaves and twigs of the Podocarpaceae plants Nageia wallichiana (C. Presl) Kuntze and Podocarpus pilgeri Foxw growing in Vietnam were first extracted by hydro-distillation and analysed by GC/MS-FID (gas chromatography/mass spectrometry-flame ionization detection). α-Pinene (39.75-53.55%) and germacrene D (22.28-25.72%) were re...

This research aimed to identify the volatile compounds of essential oils found in the rhizomes and leaves of Zingiber monophyllum Gagnep. This is the first phytochemical investigation of this species. Essential oils from the rhizomes and leaves of Z. monophyllum were obtained by hydrodistillation and analyzed by gas chromatography coupled with mass...

Meiogyne rubra Jaikhamseub, Damth. & Chaowasku sp. nova and M. vietnamica Jaikhamseub, T.A. Le & Chaowasku sp. nova (Annonaceae) from Vietnam are described and illustrated. Molecular phylogenetic reconstructions based on up to eight plastid DNA regions (matK, ndhF, rbcL and ycf1 exons; trnL intron; ndhF-rpl32, rpl32-trnL and trnL-trnF intergenic sp...

A new spirostanol steroid, aspidiata A (1), and a new spirostanol steroidal saponin, aspidiata B (2), along with three known compounds, paris saponin VII (3), daucosterol (4), and (25R)-spirostane-1β,2β,3β,4β,5β,6β-hexol (5), were isolated from whole plants of Aspidistra triradiata collected in Vietnam. Their chemical structures were established by...

Essential oils of two Asteraceae plants Blumea riparia DC. and Pluchea pteropoda Hemsl. ex Hemsl., collected from Vietnam, have been studied by hydro-distillation and GC/MS-FID (gas chromatography/mass spectrometry-flame ionization detector) analysis. Oil yields of B. riparia fresh leaves and twigs were in the range of 0.1-0.2%, whereas essential o...

Solanum melongenaL.var. esculentumNess. growingwidely in Vietnam is a member of the plants family Solanaceae. Fruits and whole plant of S. melongenahas beenused by traditional medicine to treat various diseases, such as, toothache, turgescence, pruritus, and haemorrhoids.Previous studies indicated that thisplant contain of alkaloids, anthocyanins,...

Eight compounds, including 11 β ,13‐dihydrovernolide ( 1 ), apigenin ( 2 ), kaempferol ( 3 ), quercetin 3‐ O ‐methyl ether ( 4 ), quercetin ( 5 ), syringaresinol‐ β ‐ᴅ‐glucoside ( 6 ), 3‐hydroxy‐1‐(4‐hydroxy‐3‐methoxyphenyl)‐2‐[4‐(3‐hydroxy‐1‐( E )‐propenyl)‐2,6‐dimethoxyphenoxy]propyl‐ β ‐ᴅ‐glucopyranoside ( 7 ), and 5‐(methoxymethyl)‐1 H ‐pyrrole...

Nguyen DD, Le TA, Hoang QH, Le QT, Nguyen E. 2022. Two new taxa of Curcuma sect. Ecomata (Zingiberaceae: Zingibereae), from coastal Central Vietnam. Biodiversitas 23: 2512-2519. Curcuma sixsensesensis and Curcuma vinhlinhensis, two new species belonging to subgenus Ecomata from Coastal Central Vietnam, are described and illustrated in the present a...

Heterostemma saolaense, a new species from Vietnam is described, illustrated and compared with the similar species Heterostemma maculatum. The two species differ in stem pubescence, peduncle, calyx and corolla size.

Pogostemon Desf. includes a wide range of taxa found in subtropical and tropical areas. Few works, however, have studied microanatomical characteristics of Pogostemon species and as yet identified features of Pogostemon auricularius (L.) Hassk. Thus, in this paper, we examined the taxonomic implications of root, stem and leaf morphology for species...

Phytochemical investigation applying GC (gas chromatography)-MS (mass spectrometry)/GC-FID (flame ionization detection) on the hydro-distilled essential oils of the Vietnamese medicinal plant Uvaria boniana leaf and twig lead to the detection of 35 constituents (97.36%) in the leaf oil and 52 constituents (98.75%) in the twig oil. Monoterpenes, mon...

Phytochemical investigation of the whole plants of Vernonia gratiosa Hance. led in the isolation and identification of two new stigmastane-type steroidal glucosides (1–2), namely vernogratiosides A (1), and B (2). Their chemical structures were fully elucidated based on 1 D/2D NMR spectroscopic, HR-ESI-MS data analyses, and by producing derivatives...

The hydro-distilled essential oil from the fresh aerial part of Orchidantha vietnamica K. Larsen collected from Lamdong-Vietnam was analyzed by GC-FID (Gas Chromatography-Flame Ionization Detection) and GC-MS (Gas Chromatography-Mass Spectroscopy) for the first time. The oil was characterized by the presence of volatile compounds type terpenoids, i...

Deinostigma serratum F.Wen, L.N.Tuan & D.Dien, a new species of Gesneriaceae is described and illustrated from the central Vietnam. It resembles D. eberhardtii in habit, but easily differs in several characters, especially in its odontoid margin of corolla petals. The ecological information, geographic distribution and conservation status of this n...

A new species of Aspidistra, A. sonlaensis, is described and illustrated from Son La Province in northern Vietnam. The new species is morphologically close to A. micrantha, but differs in number of perigone lobes, anther position and pistil shape. The new species is accessed as Data Deficient (DD) according to the IUCN categories and criteria.

Mangrove plant endophytic bacteria are prolific sources of bioactive secondary metabolites. In the present study, twenty-three endophytic bacteria were isolated from the fresh roots of the mangrove plant Rhizophora apiculata. The identification of isolates by 16S rRNA gene sequences revealed that the isolated endophytic bacteria belonged to nine ge...

This research aims to identify the volatile compounds from rhizomes and leaves of Newmania sontraensis. The constituents of essential oil from the rhizomes and leaves of N. sontraensis were analyzed by Gas Chromatography-Mass Spectrometry (GC/MS). Thirty-one compounds were identified in the rhizomes compared to the leaves which showed thirty-two vo...

Helicteres hirsuta Lour. is a traditional Vietnamese medicine for treating chronic liver diseases such as cirrhosis and liver cancer. Many in vitro and in vivo experiments have demonstrated that the extracts and isolated compounds from H. hirsuta have diverse pharmacological activities, including antioxidant, anti-inflammatory, and anti-cancer effe...

Plants of the genus Polyalthia can be seen as a rich resource of essential oils type terpenoids. In this study, the essential oils obtained by hydro-distillation from the leaf and stem of Polyalthia viridis were analysed by gas chromatography/mass spectrometry–flame ionization detection. Thirty-nine constituents (95.3%) were identified in the leaf...

Thottea aroangensis T.A. Le, D. Dien & Tagane (Aristolochiaceae) is described based on the specimen collected from the A Roang commune, A Luoi district, Thua Thien Hue province, central Vietnam. This species is characterized by subshrub habit 70-90 cm tall, inflorescence at base of stem close to ground level, campanulate and obscurely lobed periant...

Chemical compositions in essential oils of Amomum muricarpum Elmer were determined using GC-MS/GC-FID. In the hydro-distilled oils of aerial part and rhizome, twenty-eight and thirty-three constituents were identified, accounting for 98.73 and 97.88%, respectively. A. muricarpum essential oils were associated with the presence of monoterpenes, sesq...

Aspidistra peltata, a new species morphologically allied to A. tonkinensis (= A. fungilliformis subsp. formosa; A. formosa) discovered in northern Vietnam, is described and illustrated. From the closely related A. tonkinensis, the new species differs in having an erect stem 4–14 cm tall, much smaller leaves, smaller flowers, filamentose stamens, a...

Research on plant diversity for non-timber forest products (NTFPs) at Dakrong Nature Reserve, Quang Tri province. The study results have recorded 477 species, 325 genera, 119 families belonging to 5 vascular plant divisions, with Magnoliophyta accounting for 96.01% of the total number of species. The ten most diverse families of species have been i...

A new steroidal saponin, torvoside R (1), was isolated along with torvoside Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts of Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (1 − 3) exhibite...

Essential oils from the leaf and twig of Polyalthia suberosa (Roxb.) Thwaites were analyzed using GC‐MS/FID. A total of sixty‐three constituents were namely identified accounting for 96.03 and 94.12% in the hydro‐distilled oils of the leaf and twig, respectively. Monoterpenes, monoterpenoids, sesquiterpenes, and sesquiterpenoids were characteristic...

Billolivia lamdongensis Hareesh, T.A. Le & D.D. Nguyen sp. nova (Gesneriaceae) is described and illustrated from Central Highlands, Vietnam. It resembles B. vietnamensis but differs from the latter in having short hairs on the adaxial surface of the lamina; ovate-lanceolate bracts; linear calyx lobes 3/4 length of the corolla tube; a white corolla...

Introduction: The present study aimed to determine the chemical compositions and bioactivities of the essential oil of Atalantia sessiflora Guillaumin (A. sessiflora), including antibacterial, antimycotic, antitrichomonas, anti-inflammatory and antiviral effects. Methodology: The essential oil from leaves of A. sessiflora was extracted by hydrod...

Context: Bioactivities of Alphonsea tonkinensis A.DC have not been reported previously, while the knowledge about its chemical composition is limited. Aims: To investigate the phytochemical constituents and bioactivities of the stems and leaves of Alphonsea tonkinensis A.DC. Methods: Combination of various extraction, chromatographic methods and...

The result showed that species composition of Tracheophyta in Sao La Nature Reserve, Thua Thien Hue province is very rich and diverse. The authors have determined over 746 species, 405 genera, 134 family. The Magnoliophyta phylum has 124 families, 390 genera, 746 species. Useful plant resources comprise fruit tree accounts 34 species (2,96 %); orna...

The result showed that species composition of Tracheophyta in Sao La Nature Reserve, Thua Thien Hue province is very rich and diverse. The authors have determined over 746 species, 405 genera, 134 family. The Magnoliophyta phylum has 124 families, 390 genera, 746 species. Useful plant resources comprise fruit tree accounts 34 species (2,96 %); orna...

The rapid emergence of drug-resistant strains and novel viruses have motivated the search for new anti-infectious agents. In this study, the chemical compositions and cytotoxicity, as well as the antibacterial, antifungal, antitrichomonas, and antiviral activities of essential oils from the leaves, rhizomes, and whole plant of Hornstedtia bella wer...

Bằng cách sử dụng kết hợp các phương pháp sắc ký, bốn hợp chất gồm friedelin (1), arborinol (2), isoarborinol (3) và stigmasterol (4) đã được phân lập từ phần trên mặt đất của cây Cơm rượu hoa nhỏ (Glycosmis parviflora (Sims) Little). Cấu trúc hóa học của chúng được xác định dựa trên phân tích dữ liệu phổ cộng hưởng từ hạt nhân (1D- và 2D-NMR) và s...

The present study aimed to determine the bioactivities of essential oils extracted from the leaves of Paramignya trimera and Limnocitrus littoralis, including cytotoxicity, antiviral, antibacterial, antimycotic, and antitrichomonas effects. Herein, it was indicated that P. trimera and L. littoralis oils showed no cytotoxicity on normal cells, namel...

The present study aimed to determine the antimicrobial activity and chemical composition of leaves-extracted essential oil of Leoheo domatiophorus Chaowasku, D.T. Ngo and H.T. Le (L. domatiophorus), including antibacterial, antimycotic, antitrichomonas and antiviral effects. The essential oil was obtained using hydrodistillation, with an average yi...