Tsvetelina Angelova

Tsvetelina Angelova
University of Chemical Technology and Metallurgy | UCTM · Department of Biotechnology

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20
Publications
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154
Citations

Publications

Publications (20)
Article
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(1) Background: (KLAKLAK)2 is a representative of the antimicrobial peptide group which also shows good anticancer properties. (2) Methods: Herein, we report synthesis using SPPS and characterization by HPLC/MS of a series of shortened analogues of (KLAKLAK)2. They contain single sequence KLAKLAK as C-terminal amides. In addition, substitution of s...
Article
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This study presents an investigation of antifungal properties of hybrid materials based on silica, hydroxypropyl cellulose and ZnSO4.7H2O. The hybrid materials were synthesized by sol-gel technique and as a source of silica was used tetraethylortho silicate (TEOS). The quantity of organic substance was 5 wt. % and the zinc concentration varied from...
Article
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ABSTRACT The purpose of this work was to investigate the possibility of wood preservation by its modification with different substances through the penetration method and to study the impact of the process on some operational properties of the wood material. The experiments were conducted with poplar wood (samples 10x1x1 cm), which has low density...
Article
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Different polymerization techniques as particle formation processes for ciprofl oxacin-loaded poly (butyl cyanoacrylate) nanoparticles (CfH-PBCN) were evaluated to choose the most appropriate in terms of the resulting nanoparticles characteristics suitable for parenteral administration. The formulations prepared by the selected technique were consi...
Article
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ABSTRACT We have investigated the preparation of nanocomposite materials with the participation of SiO2 , ZnO, TiO2 and reduced graphene oxide (RGO). Stepwise reactions were applied for the introduction of the components. By X-ray diffraction was established that the obtained at 2000 C multicomponent materials were amorphous. Anatase nanoparticles...
Article
Three types of silica hybrid nanomaterials, doped with silver, were studied for their antifungal effect against fungi Penicillium chrysogenum strain 2303. The hybrid nanomaterials based on SiO2 and cellulose ethers - hydroxypropyl cellulose, hydroxypropylmethyl cellulose and carboxymethyl cellulose, and silver were prepared by sol-gel method. The a...
Article
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The biocompatibility of hybrid hydroxypropyl cellulose (HPC) hydrogels with different content of embedded silver nanoparticles (AgNPs) is revealed by testing the cytotoxicity and induction of cell death. The effect of cytotoxicity and cell death was studied on L929 fibroblasts by using MTT cytotoxicity assay, cell morphological observations and acr...
Article
Full-text available
Hybrid materials based on tetraethylorthosilicate (TEOS), hydroxypropyl cellulose (HPC) or hydroxypropyl methyl cellulose (HPMC) with silver nanoparticles were synthesized. They were analyzed and characterized using differential thermal analysis and thermo gravimetry (DTA/TG), atomic force microscopy (AFM) and static contact angle (CA) measurements...
Article
The antimicrobial effect against Saccharomyces cerevisiae 537 of silica hybrid materials based on tetraethylorthosilicate, cellulose derivates (hydroxypropyl cellulose and hydroxypropyl methyl cellulose) and silver was investigated. The silver concentration in the hybrid materials varied from 0.5 wt % to 2.5 wt %. The antimicrobial effect was quant...
Article
Full-text available
Hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropyl cellulose (HPC), or hydroxypropyl methyl cellulose (HPMC) with silver nanoparticles were synthesized. They were analyzed and characterized using differential thermal analysis and thermogravimetry, atomic force microscopy, and static contact angle measurements. It was experimen...
Article
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Antifungal effects of two type of silver-doped organic-inorganic hybrid materials against yeastCandida albicans strain 74 were studied. The hybrid materials were obtained by sol-gel method based on the interactions between SiO2 and hydroxypropyl cellulose or SiO2 and hydroxypropyl methyl cellulose. Additionally these materials were doped with diffe...
Article
Full-text available
Antibacterial SiO2 hybrid materials based on tetraethyl orthosilicate (TEOS), hydroxypropylmethylcellulose (HPMC) and silver were prepared by the sol-gel method. The content of cellulose derivate was 5 wt% and the silver concentration varied from 0.5 wt% to 2.5 wt%. The amorphous nature, morphology and antibacterial behaviour were studied. Fourier...
Article
Full-text available
The paper focused on preparation of antimicrobial silica hybrid materials based on tetraethylorthosilicate (TEOS) as SiO 2 precursors, carboxymethyl cellulose (CMC) as an organic compound and silver (AgNps). The quantity of organic substance was 10 wt.% and the silver concentration varied from 0.0 to 1.5 wt.%. The obtained hybrids were analyzed and...
Article
Antimicrobial silica hybrid materials, based on tetraethyl orthosilicate, cellulose derivates (hydroxypropyl cellulose and hydroxypropylmethyl cellulose) and silver have been prepared by the sol-gel method. The content of cellulose ethers was 5 mass % and the silver concentration varied from 0.5 to 2.5 mass %. The antifungal effect was quantified a...
Article
Silica hybrid materials containing tetraethyl orthosilicate (TEOS) as SiO2 precursor, hydroxypropyl cellulose (HPC) as an organic compound with incorporation of silver were prepared, and their structure and surface morphology were examined by FTIR measurements and SEM. The quantity of organic substance was 5 wt.% and the silver concentration varied...

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