
Tomohiro YasudaSeirei Christopher University · School of Nursing
Tomohiro Yasuda
PhD
About
110
Publications
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Introduction
Additional affiliations
March 2007 - March 2015
Publications
Publications (110)
This study examined the effects of birth weight on body composition, physical fitness, and sarcopenia in adulthood among young Japanese women. Seventy young adult women (birth weight <2500 g classified as low-birth-weight group [L-BW, n = 13] and ≥2500 g classified as not low-birth-weight group [NL-BW, n = 57]) were evaluated for body composition,...
Background: Long-term and prolonged piano performance does not provide essential skeletal muscle training benefits while increasing the risk of injury to the upper extremities. Unlike high-intensity exercise training, moderate blood flow restriction (BFR) training has been found to improve neuromuscular mechanisms with a variety of physical exercis...
Objective: Making the diagnosis of sarcopenia is not always easy and this is especially true for those with cardiovascular disease. The purpose of this study is to investigate whether it is possible to diagnose sarcopenia by using ultrasound-guided measurements of anterior femoral muscle thickness. Methods: We investigated the utility of ultrasound...
Objective] While piano performance with KAATSU has the potential to be effective in neuromuscular adaptation, its chronic training effects have not yet been studied. In this study, we investigated the effects of 3 weeks of piano performance with or without KAATSU on the adaptation of neuromuscular mechanisms.
[Methods] The subject first participate...
I examined the actual situation of the desire to be thin among young Japanese women from the perspective of ideal body shape and actual measured body shape. In total, 90 young Japanese women were evaluated using a questionnaire (perceived body shape and desired body composition change) and assessments of sarcopenia (muscle strength, physical abilit...
We investigated the physiological and perceptual responses related to piano performance with or without moderate blood flow restriction (BFR) based on acute responses of neuromuscular mechanisms. Student or professional pianists ( n = 7) performed the "Revolutionary Etude" on the piano with (Piano-BFR) and without (Piano-Ctrl) BFR. During the Piano...
We examined the actual situation of the desire to be thin among young Japanese women from the perspective of ideal body shape and actual measured body shape. In total, 90 young Japanese women were evaluated using a questionnaire (perceived body shape and desired body composition change) and assessments of physical fitness and sarcopenia (muscle str...
The purpose of this study was to compare the fitness levels of healthy young Japanese adults based on the “old” and “new” sarcopenia versions of the European Working Group on Sarcopenia in the Older People (EWGSOP1 and EWGSOP2) and the Asian Working Group for Sarcopenia (AWGS 2014 and AWGS 2019) criteria. Sixty-nine Japanese young adults were evalu...
Resistance training is an extremely beneficial intervention to prevent and treat sarcopenia. In general, traditional high-load resistance training improves skeletal muscle morphology and strength, but this method is impractical and may even reduce arterial compliance by about 20% in aged adults. Thus, the progression of resistance training methods...
[Purpose] The purpose of this study was to propose potential preventive measures against future mobility impairments and muscle loss in healthy young adults by comprehensively evaluating their status of frailty, locomotive syndrome, and sarcopenia. [Participants and Methods] A total of 83 Japanese young adults were enrolled in this study and evalua...
[Purpose] We investigated whether blood flow-restricted training known as KAATSU training, was effective for rehabilitation of a pianist with residual neurological symptoms in the upper limbs. [Participant and Methods] A pianist with residual neurological symptoms in the upper body played “Revolutionary Etude” under two conditions: piano performanc...
We examined the safety and the effects of low-intensity resistance training (RT) with moderate blood flow restriction (KAATSU RT) on muscle strength and size in patients early after cardiac surgery. Cardiac patients (age 69.6 ± 12.6 years, n = 21, M = 18) were randomly assigned to the control (n = 10) and the KAATSU RT group (n = 11). All patients...
Introduction: Surgery for cardiovascular disease is often accompanied by sarcopenia and physical frailty, and improvement of muscle mass, muscle strength, and ADL, is often difficult only with cardiac rehabilitation using aerobic exercise. The resistance training under moderately restricted muscle blood flow, named as KAATSU, induces muscle hypertr...
Introduction: In patients with heart failure, malnutrition is often associated with sarcopenia, and cachexia, closely related to the prognosis of the disease. Phase angle(PA) is an angle that expresses the resistance of the cell membrane, and is related to the health of the cell and the nutritional state of the cell membrane. It is attracting atten...
Objectives
The purpose of this study was to examine the prediction of skeletal muscle mass and maximum muscle strength using simplified morphology evaluation in young Japanese women from the thigh and calf perspective.
Methods
A total of 249 Japanese young women (aged 18–25 years) were used for data analyses in this study. Thigh and calf girths we...
Malnutrition is associated with sarcopenia, cachexia, and prognosis. We investigated the usefulness of phase angle (PhA) as a marker of sarcopenia, cachexia, and malnutrition in 412 hospitalized patients with cardiovascular disease. We analyzed body composition with bioelectrical impedance analysis, and nutritional status such as controlling nutrit...
Objective
To compare the magnitude changes in muscle thickness (MTH) of the anterior mid-thigh between supine and standing postures.
Design
Experimental.
Setting
University hospital laboratory.
Participants
A total of 283 inpatients (aged 29 to 93 years; 193 males and 90 females) with cardiovascular disease volunteered for this study.
Intervent...
[Objective] It is well known that KAATSU resistance training can produce muscle hypertrophy without deteriorating cardiovascular system in older adults. However, it is unclear whether KAATSU resistance training exceeding 12 weeks were a highly safe and effective training method for improvement of skeletal muscle mass in older adults. We examined ef...
Blood flow restriction (BFR) has the potential to augment muscle activation, which underlies strengthening and hypertrophic effects of exercise on skeletal muscle. We quantified the effects of BFR on muscle activation in the rectus femoris (RF), the vastus lateralis (VL), and the vastus medialis (VM) in concentric and eccentric contraction phases o...
The purpose of this paper was to use a Bayesian approach to compare the relative change in muscle size between magnetic resonance imaging (MRI) and ultrasound measured muscle thickness (MTH) following 6 weeks of concentric and eccentric blood flow restricted exercise. Changes at each site were as follows: concentric 50% site (MRI: 10.2%, MTH: 8.7%)...
Aims:
The purpose of this study was to examine the anthropometric, body composition, and somatotype characteristics of Japanese young women and to focus on normal-weight obesity syndrome and sarcopenia diagnosis criteria.
Methods:
A total of 124 Japanese university freshmen women were measured at body mass index (BMI), percent body fat and skele...
[Purpose] KAATSU training is a method that increases muscle activity even at low loads. In this study, we examined how different KAATSU pressure modulates elbow flexor activities during low-load elbow flexion and extension in an elderly female frail patient.
[Method] A 89-year-old female patient who had repeated hospitalization due to chronic heart...
Low force exercise training with blood flow restriction (BFR) elicits muscle hypertrophy. We investigated the effects of microvascular hypoxia (i.e., low microvascular O2partial pressures, PmvO2) during contractions on hypertrophic signaling, growth response and key muscle adaptations for increasing exercise capacity. Wistar rats were fitted with a...
We report a case in which a favorable course was obtained by using KAATSU training® and BCAA intake early after aortic valve replacement surgery. The patient was a 43-year-old male with low cardiac function who underwent aortic valve replacement surgery. Heart failure and hypotension persisted while waiting for surgery. He tended to line on a bed a...
Context:
Periodic assessment of knee extensor muscle strength and size is important for all ages to evaluate the functional status of individuals and to identify and treat those at risk for mobility problems and frailty; however, it is not fully understood whether these field-based simplified approaches correspond to evaluation in knee extensor mu...
We examined the relationship between Short Physical Performance Battery (SPPB) and clinical and laboratory factors and the effect of sarcopenia and sarcopenic obesity (SO) on clinical and laboratory factors for cardiovascular disease (CVD) inpatients. CVD male (n = 318) and female (n = 172) inpatients were recruited. A stepwise multiple-regression...
[Purpose] To examine if the SPPB is higher with healthy subjects than outpatients, which was higher than inpatients and if the SPPB can be validated assessment tool for strength tests and lower extremity morphological evaluation in cardiovascular disease patients. [Subjects and Methods] Twenty-four middle aged and older adults with cardiovascular d...
[Purpose] We examined the use and safety of KAATSU training by a national survey in 2016.
[Methods] We provided a questionnaire survey (web input) to attendees of the annual academic meeting of the Japan KAATSU Training Society and on the website of the academic society on October 29, 2016. The reply deadline was set at to about approximately 2 mon...
[Objective] It is well known that knee meniscectomy is one of the major knee surgeries, which induces thigh muscle atrophy. However, it is unclear whether thigh muscle size after knee meniscectomy can be improved with KAATSU training. We examined effect of KAATSU training on thigh muscle size and safety for a patient with knee meniscectomy.
[Method...
The purpose of this study was to examine the relationship between field-based simplified approaches and knee extensor muscle strength/size in young men. Knee extensor muscle thickness (MT) of 104 healthy university freshmen was measured at the anterior half of thigh length; maximal voluntary isometric contraction (MVIC) was measured when subjects p...
We examined the effect of elastic band training with blood flow restriction (BFR) on thigh muscle size and vascular function in older women. Older women were divided into three groups: low-intensity elastic band BFR training (BFR-Tr, n = 10), middle- to high-intensity elastic band training (MH-Tr, n = 10), and no training (Ctrl, n = 10) groups. BFR...
Skeletal muscle is a plastic organ that adapts its mass to various stresses by affecting pathways that regulate protein synthesis and degradation. This study investigated the effects of repetitive restriction of muscle blood flow (RRMBF) on microvascular oxygen pressure (PmvO2), mammalian target of rapamycin (mTOR) signaling pathways, and transcrip...
Femoral head avascular necrosis is a condition in which part of the femoral head undergoes necrosis due to decreased blood flow. The femoral head gradually disintegrates causing pain and even today, there are no effective rehabilitation methods other than symptomatic treatment such as decreasing the load on the hip joints with the use of a cane or...
We examined the effects of detraining after blood flow-restricted (BFR) low-load elastic band training on muscle size and arterial stiffness in older women.
Fourteen women were divided into BFR training (BFR-T) or non-BFR training (CON-T). Each group participated in 12 weeks of arm curl and press down training using an elastic band either with (BFR...
We investigated the effects of 6 weeks of detraining on muscle size and strength in young men who had previously participated in 6 weeks (3 days/week) of 30 % of concentric one-repetition maximal (1-RM) dumbbell curl training [one arm: concentric blood flow restricted (BFR) exercise (CON-BFR); the other arm: eccentric BFR exercise (ECC-BFR)]. MRI-m...
The effects on muscle swelling were compared between low-load resistance exercise to exhaustion with (BFR) and without blood flow restriction (NBFR).
Ten young men [aged 27 (SD 5) years, standing height 1.74 (SD 0.05) m, body mass 70.3 (SD 4.3) kg] performed 20 % of one repetition maximal dumbbell curl exercise to exhaustion (four sets, rest interv...
We examined the effect of low-load, elastic band resistance training with blood flow restriction (BFR) on muscle size and
arterial stiffness in older adults. Healthy older adults (aged 61–85 years) were divided into BFR training (BFR-T, n = 9) or non-BFR training (CON-T, n = 8) groups. Both groups performed low-load arm curl and triceps down exerci...
We investigated the effects of 3 weeks of detraining on muscle cross-sectional area (CSA) and one-repetition maximum strength (1-RM) in young men who had previously participated in 6 weeks (3 days week−1) of bench press training [blood flow restricted low-intensity (LI-BFR; n = 10, 20% 1-RM) or high-intensity (HI; n = 7, 75% 1-RM)]. Bench press 1-R...
Although blood flow-restricted low-intensity resistance training (BFR-RT) increases muscle size and strength in older adults, the effect of detraining on muscle adaptation is unclear.
We investigated the effects of 24 weeks of detraining on thigh muscle cross-sectional area (CSA) and one-repetition maximum strength (1-RM) in older adults who had pr...
Low-intensity resistance exercise with blood flow restriction (BFR) has been shown to induce a prominent increase in muscle activation in response to muscle fatigue. However, the magnitude of muscle fatigue between continuous (Con-BFR) and intermittent BFR (Int-BFR, BFR only during exercise) is currently unknown. We examined the effect of Con-BFR o...
Reactive oxygen species (ROS) mediate various signaling pathways that underlie vascular inflammation in atherogenesis and cardiovascular diseases. Cardiac rehabilitation (CR) has a variety of multiple beneficial effects, including anti-inflammatory effects. The purpose of the present study was to investigate the effects of CR on ROS in patients wit...
Previous studies have shown that blood flow-restricted low-intensity resistance training (BFR-RT) causes muscle hypertrophy while maintaining arterial function in young adults. We examined the effects of BFR-RT on muscle size and arterial stiffness in older adults. Healthy subjects (ages 61-84 years) were divided into BFR-RT (n = 9) or non-training...
Low-intensity blood-flow restriction (BFR) resistance training significantly increases strength and muscle size, but some studies report it produces exercise-induced muscle damage (EIMD) in the lower body after exercise to failure.
To investigate the effects of a pre-set number of repetitions of upper body concentric and eccentric exercise when com...
We examined the effects of blood flow-restricted, low-intensity resistance exercise (termed kaatsu), using an elastic band for resistance, on muscle activation in patients with cardiovascular diseases. Six patients with cardiovascular diseases [male, 69±12 (SD) years old, five old myocardial infarction and one dilated cardiomyopathy] performed bice...
We investigated the acute and chronic effects of low-intensity concentric or eccentric resistance training with blood flow restriction (BFR) on muscle size and strength. Ten young men performed 30% of concentric one repetition maximal dumbbell curl exercise (four sets, total 75 reps) 3 days/week for 6 weeks. One arm was randomly chosen for concentr...
To compare the effects of a periodic resistance training (PTR) program with those of a continuous resistance training (CTR) program on muscle size and function, 14 young men were randomly divided into a CTR group and a PTR group. Both groups performed high-intensity bench press exercise training [75 % of one repetition maximum (1-RM); 3 sets of 10...
We examined the effects of blood flow-restricted, low-intensity resistance exercise (termed kaatsu) using an elastic band for resistance on muscle activation. Nine men performed triceps extension and biceps flexion exercises (four sets respectively) using an elastic band for resistance with blood flow restriction (BFR) or CON (unrestricted blood fl...
We examined the effects of high-intensity resistance training (HIT) and low-intensity blood flow-restricted (LI-BFR) resistance training on carotid arterial compliance. Nineteen young men were randomly divided into HIT (n = 9) or LI-BFR (n = 10) groups. The HIT and LI-BFR groups performed 75 and 30 %, respectively, of one-repetition maximum (1-RM)...
The purpose of this study was to compare the muscle hypertrophic response in women during both the follicular (FP) and the luteal phase (LP) of their menstrual cycles following short-term, low-intensity resistance training combined with blood flow restriction (BFR). Eight eumenorrheic women and five men, all previously untrained, performed unilater...
The purpose of this study was to compare the component characteristics of thigh muscle volume in Japanese young and older men. The subjects in both young (YM, n = 15) and older (OM, n = 13) men were physically active (performed aerobic-type exercise 1-3 times per week), but none of the subjects had regularly participated in resistance training for...
Walk training combined with blood flow restriction (BFR) leads to hypertrophic effects in leg muscle, but the underlying physiological mechanisms are poorly understood. We examined the time course of the acute effects of BFR slow walk (BFR-slow; walking speed 56 m/min), BFR fast walk (BFR-fast; walking speed 87 m/min), and control walk (CON-slow; w...
It has been reported that low-intensity exercise training with restriction of muscular blood flow (LI-BFR) results in a significant increase of muscle size and strength, although the mechanisms of BFR-induced muscle adaptation are still poorly understood. Changes in muscle activation level during a BFR exercise session may be an important factor fo...
As demographic aging continues in Japan, the number of very elderly individuals aged 75 years or older is increasing rapidly, as is the number of bedridden, elderly individuals, with ramifications extending to economic problems such as health care costs and insurance for long-term care. Consequently, there is a great importance to questions of how...
Venous compliance declines with age and improves with chronic endurance exercise. KAATSU, an exercise combined with blood flow restriction (BFR), is a unique training method for promoting muscle hypertrophy and strength gains by using low-intensity resistance exercises or walking. This method also induces pooling of venous blood in the legs. Theref...
We examined the relationship between training-induced limb and trunk muscle hypertrophy in high-intensity resistance training (HIT) or blood flow-restricted low-intensity resistance training (LI-BFR) programmes. Thirty young men were divided into three groups: HIT (n = 10), LI-BFR (n = 10) and non-training control (CON, n = 10). The HIT and LI-BFR...
To determine muscle adaptations to retraining after short-term detraining, we examined the effects of continuous and interrupted resistance training on muscle size and strength in previously untrained men. Fifteen young men were divided into continuous training (CTr) or retraining (RTr) groups and performed high-intensity bench press training. The...
Muscular blood flow reduction (BFR) during multiple sets of low-intensity exercise training has been shown to elicit muscle hypertrophy and strength gain. Several hypotheses have been proposed to explain the hypertrophic adaptations to low-intensity BFR exercise, which include muscle fatigue with metabolic stress. However, the change in intramuscul...
We investigated the relationship between age and muscle size in both the appendicular and trunk regions of 1507 Japanese men and women aged 20 to 95 years. Seven hundred twenty-two men (young [aged 20-39 years], n = 211; middle-aged [aged 40-59 years], n = 347; and old [aged 6095 years], n = 164) and 785 women (young, n = 207; middle-aged, n = 341;...
We investigated the combined effect of low-intensity blood flow restriction and high-intensity resistance training on muscle adaptation. Forty young men (aged 22-32 years) were randomly divided into four groups of ten subjects each: high-intensity resistance training (HI-RT, 75% of one repetition maximum [1-RM]), low-intensity resistance training w...
The number of patients with dementia is increasing markedly, and effective treatment and methods for prevention are needed. Moderate exercise decreases the progression of dementia. We report a case of dementia presenting remarkable improvement in activities of daily living (ADL) through KAATSU training. The patient was a 78-year-old woman with brai...
High-intensity exercise shares similarities with acute phase responses of inflammatory diseases. We investigated the influences of acute exercise on inflammatory markers, plasma pentraxin3 (PTX3) and serum high-sensitive C-reactive protein (CRP) (hsCRP). Nine healthy male subjects (41 ± 3 years old) participated. Each subject performed three types...
We examined the effects of walk training combined with leg blood flow reduction (BFR) on muscle hypertrophy as well as on peak oxygen uptake (VO₂ peak) in older individuals. Both the BFR walk training (BFR-Walk, n = 10, age; 64 ± 1 years, body mass index [BMI]; 22.5 ± 0.9 kg/m²) and control walk training (CON-Walk, n = 8, age; 68 ± 1 years, BMI; 23...
Concurrent improvements in aerobic capacity and muscle hypertrophy in response to a single mode of training have not been reported. We examined the effects of low-intensity cycle exercise training with and without blood flow restriction (BFR) on muscle size and maximum oxygen uptake (VO2max). A group of 19 young men (mean age ± SD: 23.0 ± 1.7 years...
Single-joint resistance training with blood flow restriction (BFR) results in significant increases in arm or leg muscle size and single-joint strength. However, the effect of multijoint BFR training on both blood flow restricted limb and non-restricted trunk muscles remain poorly understood. To examine the impact of BFR bench press training on hyp...