Tolga Göktürk- PhD
- Lecturer at Muğla University
Tolga Göktürk
- PhD
- Lecturer at Muğla University
About
27
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Introduction
I am currently working on design, synthesis, characterization and anticancer activity of metal complexes of Schiff bases containing 1,2,3-triazol group or sulfonamide derivatives. DNA/BSA interaction studies including a wide range of techniques are a part of my research work. Topoisomerase inhibition of the potent metal complexes is also explored.
Current institution
Publications
Publications (27)
A new Cu (II) complex with 1,3‐dimethyl‐5‐acetyl‐barbituric acid was synthesized and characterized using elemental analysis, magnetic moment measurements, FTIR, and X‐ray diffraction. Structural analysis revealed that the Cu (II) complex belongs to the triclinic system with the P ‐1 space group. The copper (II) ion is penta‐coordinated via five oxy...
We report herein a new 1,2,3-triazole derivative, namely, 4-((1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2-hydroxybenzaldehyde, which was synthesized by copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC). The structure of the compound was analyzed using Fourier transform infrared spectroscopy (FTIR), 1H NMR, 13C NMR, UV–vis, and elem...
We report herein two new 1,4-disubstituted 1,2,3-triazole derivatives which were synthesized by copper(I)-catalyzed azide alkyne cycloaddition (CuAAC). Their structures were elucidated by FTIR, 1H NMR, 13C APT NMR, MALDI-TOF-MS and elemental analysis. Moreover, X-ray crystallography studies of compound 3 demonstrated that the compound adapted tricl...
We report a new series of isatin-oxime-based Schiff base derivatives (p–H, p–Cl, p–CH3). Structural analyses of the compounds were conducted through FTIR, ¹H NMR, UV–Vis, and elemental analyses. X-ray crystallography demonstrated that compounds 1 and 2 adopted an orthorhombic crystal system with a P bca space group. Hirshfeld surface (HS) analysis...
In recent years, studies on the design and synthesis of artificial nucleases with biological, structural and coordination properties have been increasing. With this study, mononuclear complex compounds were obtained with Cu(II), Ni(II) and Zn(II) transition metal ion salts of bis(acylhydrazone) ligand, which has the potential to show biological act...
Providing the reader with an up-to-date digest of the most important current research carried out in the field, this volume is compiled and written by leading experts from across the globe. It reviews the trends in electrochemical sensing and its applications and touches on research areas from a diverse range, including microbial fuel cells, 3D pri...
We reported herein a new 1,2,4-triazine derivative, 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline, synthesized by cyclization of p‑chloro isonitrosophenylhydrazine with 2-quinolinecarboxaldehyde. Its structure was elucidated by FTIR, 1H NMR, 13C APT NMR, elemental analyses, and also its molecular and crystal structures were determined by singl...
The title compound, C50H42N4NiO6P2·2(ClO4) was synthesized serendipitously by the reaction of Ni(ClO4)2.6H2O with newly synthesized Schiff base ligand and PPh3 in MeOH and its molecular and crystal structures were determined by single crystal X-ray analysis. It belongs to triclinic system P -1 space group with a = 10.7936 (4) Å, b = 12.2926 (4) Å,...
Cu(II) complex containing p-Cl-isonitrosoacetophenone based on N4-type Schiff base ligand was synthesized and characterized by elemental analysis, FTIR, ¹H NMR, ¹³C NMR and UV-Visible. The crystal structure of the synthesized complex was determined by single crystal X-ray analysis. In the crystal structure, the intermolecular hydrogen bonds link th...
New hydrazone derivate, (1Z,2E)-2-(2-(1-(1,3-dimethyl-2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)ethyl)hydrazineylidene)-2-(p-tolyl)acetaldehyde oxime (H2L) was synthesized by 5-acetyl-1,3-dimethyl-barbituric acid and p-methyl isonitrosophenylhydrazine. Its molecular and crystal structures were determined by single crystal X-ray analysis. It bel...
(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4-Nitrophenyl)-2-oxoacetaldehyde oximes (II) were synthesized from 4′-hydroxyacetophenone and 4′-nitroacetophenone, respectively. Their structures were elucidated by elemental analyses, ¹H-NMR, UV-Vis and also their molecular and crystal structures were determined by single...
Nickel (II) complexes containing p-substitute (–H, –CI, –CH3, –OCH3) isonitrosoacetophenone-based bis(oxime) ligands were synthesized by metal template method and characterized by elemental analyses, molar conductance, magnetic susceptibility, IR, 1H-NMR, UV–visible and mass spectra. Analytical data showed that all the complexes exhibited 3:2 (meta...
The title compound, C13H14BrN3O2, was synthesized by click chemistry (CuAAC) using 4-bromobut-1-yne and ethyl 4-azidobenzoate. Its molecular structure was determined by 1H NMR, 13C NMR, IR spectra, elemental analysis, and the crystal structure was determined by single crystal X-ray diffraction analysis. It belongs to monoclinic system: space group...
Four new Schiff-base hydrazone ligands were synthesized by the condensation of 2-and 4-aminobenzoylhydrazone with 3-(4-acetylphenoxy)-N,N,N-trimethylpropane-1-ammonium and 5-(4-acetylphenoxy)-N,N,N-trimethylpentane-1-ammonium salts. The structures of the ligands were confirmed by means of NMR, FTIR, and elemental analysis. The mononuclear and binuc...
Abstract: Two new N,N,N-trimethylpropane-1-ammonium and N,N,N-trimethylpentane-1-ammonium conjugated acetophenone-(4-hydroxybenzohydrazone) ligands, (E)-3-(4-(1-(2-(4-hydroxybenzoyl)hydrazono)ethyl)phenoxy)-N,N,N-trimethylpropan-1-ammonium perchlorate (H2L1) and (E)-3-(4-(1-(2-(4-hydroxybenzoyl)hydrazono)ethyl)phenoxy)- N,N,N-trimethylpentane-1-amm...
Aerial parts of Salvia albimaculata Hedge & Hub.-Mor., Salvia potentillifolia Boiss & Heldr. ex Bentham. and Salvia nydeggeri Hub.-Mor. from Soutwest Anatolia, Turkey were evaluated to determine their phenolic compounds and antioxidant properties. According to the ultra performance liquid chromatography with electrospray ionization tandem mass spec...
In this study, a rapid and multiple method has been proposed which can be used in determination of more than 130 pesticide residues at ppb (μg/L) level in water samples. For this purpose, a Kuderna-Danish Evaporative Concentrator, which was used for enrichment of the analyte concentration in the samples and gas chromatography coupled mass spectrome...
Phenolic compounds, which are secondary metabolites of plants, are one of the main groups of compounds that provide antiallergic, antiinflammatory, antimicrobial, antioxidant, cardioprotective properties of medicinal and aromatic plants. These broad physiological effects that they possess lead researchers to examine the phenolic contents of plants....
In this study, the components of the volatile oil obtained from Laurus nobilis leaves by steam distillation were determined using Agilent 6890 Gas Chromatography (GC) - 5975 Mass Spectrometry (MS). The antioxidant activities of different extracts of L. nobilis leaves were determined by using DPPH•(2,2-diphenyl-1-picrylhydrazyl) free radical scaveng...
