Toktam ShirazianUniversity of Alberta | UAlberta
Toktam Shirazian
Doctor of Philosophy
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![Substrates scope for the formal [4+2] allenoate based cycloaddition...](publication/362523189/figure/fig5/AS:11431281246508355@1716386529818/Substrates-scope-for-the-formal-4-2-allenoate-based-cycloaddition-reaction-for-the_Q320.jpg)
Base‐promoted formal [4+2] cycloaddition reaction of (Z)‐2‐(2‐hydroxy‐2‐alkylvinyl)quinoline‐3‐carbaldehydes and allenoates represents an efficient method for the synthesis of functionalized acridines through a sequential Michael addition, aldol condensation, and isomerization process in a mild condition. This new approach tolerates a wide range of...
