Tofazzal Islam

Tofazzal Islam
Bangabandhu Sheikh Mujibur Rahman Agricultural University | BSMRU · Institute of Biotechnology and Genetic Engineering

FBAS (BAS) and Ph D (Hokkaido), Fulbright Visiting Scholar (West Virginia), AvH Fellow (Goettingen) Commonwealth Fellow (Nottingham) Fellow of Bangladesh Academy of Sciences
Head, Plant Biotechnology Discipline

About

486
Publications
186,368
Reads
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Introduction
Md. Tofazzal Islam, FBAS (Bengali: মোঃ তোফাজ্জল ইসলাম) is a biotechnologist, educator and author from Bangladesh. He is a Professor and Director of the Institute of Biotechnology and Genetic Engineering (IBGE) of Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU). He is an elected fellow of Bangladesh Academy of Sciences (FBAS). Further details at http://en.wikipedia.org/wiki/Md._Tofazzal_Islam http://btlbsmrau.org
Additional affiliations
July 2019 - July 2021
Bangabandhu Sheikh Mujibur Rahman Agricultural University
Position
  • Managing Director
June 2019 - present
Bangladesh Academy of Sciences
Position
  • Fellow
Description
  • Elected as the Fellows of BAS
September 2017 - June 2018
West Virginia University
Position
  • Fulbright Visiting Scholar
Education
September 2017 - June 2018
West Virginia University
Field of study
  • Molecular Plant Pathology
June 2015 - July 2015
Gifu University
Field of study
  • Bioactive natural products
January 2013 - June 2014
Queen Mary, University of London
Field of study
  • Leadership in Higher Education

Publications

Publications (486)
Chapter
Innovative farming practices in the traditional agriculture have significantly been progressed in last 1,000 years. Most of these aboriginal agricultural methodologies were not finely honed. Concurrent improvement of biochemistry and engineering, farming practices were also rapidly improved during the early forty years of the twentieth century. Aft...
Article
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Food waste management is a critical environmental issue in many developing countries, including Bangladesh, due to unplanned food waste disposal and lack of dedicated food waste legislation. In those countries, a significant amount of food waste is discarded to the environment rather than being recycled. In Bangladesh, food waste is traditionally o...
Chapter
Plant growth-promoting rhizobacteria (PGPR) are regarded as the biostimulants for plant growth and development. These bioagents are also used as the bioprotectants of plants to combat the biotic and abiotic stresses in plants. The diverse mechanisms of the PGPR for regulating plant nutrition and defending the stressful conditions of plant growth ar...
Article
Summary Efficient pathogen diagnostics and genotyping methods enable effective disease management and breeding, improve crop productivity and ensure food security. However, current germplasm selection and pathogen detection techniques are laborious, time‐consuming, expensive, and not easy to mass‐scale application in the field. Here, we optimized a...
Chapter
Fungal pathogens are one of the major threats to global food safety and security. Chemical fungicides are highly effective and convenient for their management. Unfortunately, indiscriminate use of fungicides poses serious threats on ecosystem as well as on every kind of living organism dwelling on the earth. At present, Bacillus-based biotic stress...
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Full-text available
Magnaporthe oryzae is one of the most destructive fungal pathogen causing blast diseases in at least 50 grass species including wheat and rice. Although there has been comprehensive study on the fungicidal control of blast diseases, the development of pathogen resistance to commercially available products makes this approach inefficient. Novel stra...
Article
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Drought is one of the most destructive abiotic stresses that impact the growth, physiology, yield, and nutritional quality of seeds of crop plants. In modern agriculture, the use of nanoparticles can be beneficial due to their large surface area and higher potentiality to enter into the plant leaf during foliar application. This study aims to evalu...
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The COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has created an urgent global situation. Therefore, it is necessary to identify the differentially expressed genes (DEGs) in COVID-19 patients to understand disease pathogenesis and the genetic factor(s) responsible for inter-individual variability and dis...
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Wheat blast caused by the Magnaporthe oryzae Triticum (MoT) pathotype is one of the most damaging fungal diseases of wheat. During the screening of novel bioactive secondary metabolites, we observed two marine secondary metabolites, bonactin and feigrisolide C, extracted from the marine bacteria Streptomyces spp. (Act 8970 and ACT 7619), remarkably...
Article
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In this study, the feasibility of two heterogeneous catalysis (non-Fenton heterogeneous catalysis and catalytic ozonation) was evaluated for the oxidative transformation of the fungicide procymidone and its major metabolite (3,5-dichloroaniline; 3,5-DCA) under a pilot lab experiment. Among the studied treatments, only H2O2 or O3 significantly oxidi...
Preprint
Full-text available
Faba bean ( Vicia faba L.), a promising grain legume, widely grown in central and northern part of Bangladesh. Disease symptoms resembling to collar and root rot was observed in an experimental field of Bangladesh Agricultural University, Mymensingh, Bangladesh. Disease incidence was ranged between 11–19%. Water-soaked sunken lesions were appeared...
Article
Fusarium head blight (FHB) is a worldwide devastating disease of small grain cereals and Fusarium graminearum species complex (FGSC) is the major pathogen causing the disease. The epidemics of FHB lead to the reduction of grain yield and economic losses. Additionally, mycotoxins produced by the FHB pathogens are hazardous to the health of human and...
Article
Magnaporthe oryzae, the causal agent of blast diseases, is a destructive filamentous fungus that infects many plants including most economically important food crops, rice, wheat, pearl millet and finger millet. M. oryzae has numerous pathotypes because of its high host-specificity in the field. The Oryza pathotype (MoO) of M. oryzae is the most de...
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Soil salinity has emerged as a serious issue for food security due to global climate change. It is estimated that currently about 62 million hectares or 20 percent of the world’s irrigated land is affected by salinity. Salinity is a serious problem in the coastal areas of Bangladesh. Isolation of salt-tolerant plant growth-promoting bacteria (PGPB)...
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Background Mastitis pathogenesis involves a wide range of opportunistic and apparently resident microorganims including bacteria, viruses and archaea. In dairy animals, microbes reside in the host, interact with environment and evade the host immune system, providing a potential for host-tropism to favor mastitis pathogenesis. To understand the hos...
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This pilot investigation aimed to evaluate the removal efficiency and the underlying biocatalytic pathways of immobilized fungal laccase during the oxidative biotransformation of a non-phenolic metabolite, 3,5-dichloroaniline (3,5-DCA) derived from dicarboximide fungicides. The maximum loading of laccase on the microporous support surfaces could re...
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The COVID-19 threatens nearly most of the world's population with a significant mortality rate over the last 2 years. The main cause of death in those infected with SARS-CoV-2 is acute lungs infection, which is brought about by increased inflammatory activity, oxidative anxiety, and inflammatory reactions in the respiratory tract. To date, there is...
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Protein kinases (PKs), being key regulatory enzymes of a wide range of signaling pathways, are potential targets for antifungal agents. Wheat blast disease, caused by Magnaporthe oryzae Triticum (MoT), is an existential threat to world food security. During the screening process of natural metabolites against MoT fungus, we find that two protein ki...
Article
Full-text available
The application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on humans and the environment. Therefore, alternative approaches for crop protection through microbial or microbe‐originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease cause...
Preprint
Wheat, the most important food crop, is threatened by a blast disease pandemic. Here, we show that a clonal lineage of the wheat blast fungus recently spread to Asia and Africa following two independent introductions from South America. Through a combination of genome analyses and laboratory experiments, we show that the decade-old blast pandemic l...
Article
The in vitro compatibility of the entomopathogenic fungus, Cladosporium cladosporioides BOU1, with the crude extract of three plants viz. Calotropis gigantea, Vitex negundo and Carissa macrocarpa at a concentration of 1% and 2% was investigated. The compatibility of the fungal isolate with the plant extracts was calculated using the biological inde...
Chapter
Full-text available
Abstract Pesticides are biological or chemical agents that can protect plants from various pests including insects and pathogens. Injudicious use of chemical pesticides has led to severe health hazards, environmental pollution, and increased cost of production. Thus, novel approaches are necessary to protect the crop plants with minimal or no delet...
Preprint
Full-text available
Application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on human and environment. Therefore, alternative approaches for crop protection through microbial or microbe originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease caused by Magn...
Article
Full-text available
Wheat blast, caused by the Magnaporthe oryzae Triticum (MoT) pathotype, threatens wheat production in many countries, including Bangladesh. Traditional fungicides are ineffective in combating this pathogen, and no resistant wheat variety is available. This study investigated the mechanism of wheat blast suppression by a nanostructured TiO2 nanocata...
Preprint
Full-text available
Application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on human and environment. Therefore, alternative approaches for crop pro-tection through microbial or microbe originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease caused by Mag...
Article
Background Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in many fruits and vegetables, which is highly investigated for its pharmacological effect and benefit to human health. Purpose This systematic review critically discu...
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Nanotechnology is emerging as a tool for improving crop production by enhancing the tolerance of crop plants to various stresses. Various kinds of nanoparticles (1–100 nm in size) show high performances in genetic gain, nutrient security, soil improvement, and sustainability in crop production. The promise of nanotechnology in crop production is di...
Preprint
Artemisia annua L. produces artemisinin (qinghaosu), which is inhibitory against malarial parasite, Plasmodium falciparum . Genetic engineering is thought to be one of the most reasonable approaches to enhance the production of artemisinin by A. annua plant. This study aimed to clone and investigate a growth regulatory cytochrome p450 gene from A....
Article
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A 2NvS chromosomal segment carrying bread wheat variety, BARI Gom 33 (‘BG33’), showed tolerance to terminal heat stress and higher yield over a heat-tolerant non-2NvS BARI Gom 26 (‘BG26’) and a heat-susceptible Pavon 76 (‘Pavon’). This study aimed to ascertain the potential of the 2NvS ‘BG33’ in terminal heat-induced oxidative stress tolerance comp...
Preprint
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SARS-CoV-2 continues to spread and evolve worldwide, despite intense efforts to develop multiple vaccines and therapeutic options against COVID-19. Moreover, the precise role of SARS-CoV-2 in the pathophysiology of the nasopharyngeal tract (NT) is still unfathomable. Therefore, we used the machine learning methods to analyze 22 RNA-seq datasets fro...
Preprint
The emergence of novel coronavirus infectious disease-2019 (COVID-19) in December 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has traumatized the whole world with the ongoing devastating pandemic. After droplet mediated transmission of infectious virus particle, and subsequent tissue tropism through the upper and lo...
Preprint
Heat stress alters photosynthetic components and antioxidant scavenging system, negatively affecting plant growth and development. Plants overcome heat stress damage through an integrated network involving enzymatic and non-enzymatic antioxidants. The aim of the study was to assess physiological and biochemical responses in contrasting thermotolera...
Article
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Blast diseases of rice and wheat are known to be caused by the specific pathotypes of Magnaporthe oryzae (syn. Pyricularia oryzae), M. oryzae Oryzae (MoO) and M. oryzae Triticum (MoT), respectively. Rice blast disease has been seen in Bangladesh from a very ancient time. However, Bangladesh's first epidemic outbreak of wheat blast was recorded in 2...
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Full-text available
Motile Aeromonas septicaemia (MAS) caused by Aeromonas spp. is one of the major fish diseases that causes substantial losses in the aquaculture industry. The present study was conducted to screen the in vitro inhibitory effects of garlic extracts on Aeromonas veronii isolated from MAS, evaluate the effects of dietary inclusion of garlic extracts on...
Article
Radiation for medical use is a well-established therapeutic method with an excellent prognosis rate for various cancer treatments. Unfortunately, a high dose of radiation therapy comes with its own share of side effects, causing radiation-induced non-specific cellular toxicity; consequently, a large percentage of treated patients suffer from chroni...
Article
Full-text available
Blast diseases of rice and wheat are known to be caused by the specific pathotypes of Magnaporthe oryzae (syn. Pyricularia oryzae), M. oryzae Oryzae (MoO) and M. oryzae Triticum (MoT), respectively. Rice blast disease has been seen in Bangladesh from a very ancient time. However, Bangladesh’s first epidemic outbreak of wheat blast was recorded in 2...
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Full-text available
Recurring outbreaks of emerging and re-emerging zoonoses serve as a reminder that the health of humans, animals, and the environment are interconnected. Therefore, multisectoral, transdisciplinary, and collaborative approaches are required at local, regional, and global levels to tackle the ever-increasing zoonotic threat. The ongoing pandemic of C...
Preprint
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The nasopharyngeal tract (NT) of human is a habitat of a diverse microbial community that work together with other gut microbes to maintain the host immunity. In our previous study, we reported that SARS-CoV-2 infection reduces human nasopharyngeal commensal microbiome (bacteria, archaea and commensal respiratory viruses) but increases the abundanc...
Chapter
Bacillus is one of the most widely distributed genera of bacteria. It produces various groups of bioactive compounds such as cyclic lipopeptides, surfactins, iturins, fengycins, various polyketide-derived nonribosomal peptides, linear lipopeptides, enzymes, and δ-endotoxins with strong surfactant, antimicrobial, and insecticidal properties. Biosynt...
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Dragon fruit (Hylocereus polyrhizus) is an economically promising fruit in Bangladesh. The cultivation of dragon fruit has increased fourfold within a decade due to its popularity. Recently, a new disease known as stem canker was reported in some plantations of dragon fruit in Bangladesh, which forced some farmers to abandon their cultivation. This...
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Insect pest poses a major threat to agricultural commodities and profi table crop production. To overcome the pest problem, farmers use diff erent kinds of chemical pesticides, that generate negative impacts on the environment and human health. Usage of pheromones to control insect pest provide numerous benefi ts. Pheromone is a semiochemical produ...
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Apiculture has shown considerable development in honey bee rearing, and honey and other byproducts manufacturing that lead to an increase in pollination and conservation of the ecosystem. Precision apiculture (PA) is an apiary management strategy based on the monitoring of individual bee colony using a set of instrumentation to minimize resource co...
Chapter
Various kinds of abiotic stresses such as drought, salinity, extreme heat and cold, and heavy metal contamination in soils significantly have impact on crop production. Due to global climate change, the severity of these stresses is increased. Therefore, development of new abiotic stress-tolerant crop variety is needed for feeding the ever-increasi...
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Heavy metals occur naturally in very small amounts in living organisms, but exposure to their higher concentrations is hazardous. Heavy metals at hazardous levels are commonly found in foodstuffs of Bangladesh, mainly due to the lack of safety guidelines and poor management of industrial effluents. Several lines of evidence suggest that the level o...
Chapter
Pesticides are biological or chemical agents that can protect plants from various pests including insects and pathogens. Injudicious use of chemical pesticides has led to severe health hazards, environmental pollution, and increased cost of production. Thus, novel approaches are necessary to protect the crop plants with minimal or no deleterious ef...
Article
Full-text available
Dragon fruit (Hylocereus polyrhizus) is a high value newly introduced fruit crop in Bangladesh. It has 14 drawn considerable public attention due to its appealing flesh color, sweet taste and fruit qualities. 15 Recently, basal rot of dragon fruit plants was observed in several farmer's fields, nurseries and in the 16 research field of Bangabandhu...
Preprint
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Background Jackfruit (Artocarpus heterophyllus Lam.) is a tropical and sub-tropical fruit tree distributed in Asia, Africa, and South America. It is the national fruit of Bangladesh and produces fruit in the summer season only. However, a year-round jackfruit variety, BARI Kanthal-3 developed by Bangladesh Agricultural Research Institute (BARI) pro...
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Full-text available
The microbiota of the nasopharyngeal tract (NT) play a role in host immunity against respiratory infectious diseases. However, scant information is available on interactions of SARS-CoV-2 with the nasopharyngeal microbiome. This study characterizes the effects of SARS-CoV-2 infection on human nasopharyngeal microbiomes and their relevant metabolic...
Article
Full-text available
The microbiota of the nasopharyngeal tract (NT) play a role in host immunity against respiratory infectious diseases. However, scant information is available on interactions of SARS-CoV-2 with the nasopharyngeal microbiome. This study characterizes the effects of SARS-CoV-2 infection on human nasopharyngeal microbiomes and their relevant metabolic...
Article
Full-text available
This study aimed to isolate and characterise the pathogen associated with Alternaria leaf spot on broccoli and to evaluate the inhibitory effects of fungicides against it. We isolated and identified the fungal pathogen as Alternaria sp. using morphological and cultural methods. Based on the aligned sequences of the internal transcribed spacer (ITS)...
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Full-text available
Nanomaterials (NMs) are emerging novel tools for preserving quality, enhancing shelf life, and ensuring food safety. Owing to the distinctive physicochemical characters, engineered NMs under varying sizes and dimensions have great potentials for application in the manufacturing, packaging, processing, and safety of quality agrifood. The promise of...