Tofazzal Islam

Tofazzal Islam
Bangabandhu Sheikh Mujibur Rahman Agricultural University | BSMRU · Institute of Biotechnology and Genetic Engineering

FBAS (BAS) and Ph D (Hokkaido), Fulbright Visiting Scholar (West Virginia), AvH Fellow (Goettingen) Commonwealth Fellow (Nottingham) Fellow of Bangladesh Academy of Sciences
Head, Plant Biotechnology Discipline

About

525
Publications
201,425
Reads
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6,830
Citations
Citations since 2017
312 Research Items
5743 Citations
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Introduction
Md. Tofazzal Islam, FBAS (Bengali: মোঃ তোফাজ্জল ইসলাম) is a biotechnologist, educator and author from Bangladesh. He is a Professor and Director of the Institute of Biotechnology and Genetic Engineering (IBGE) of Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU). He is an elected fellow of Bangladesh Academy of Sciences (FBAS). Further details at http://en.wikipedia.org/wiki/Md._Tofazzal_Islam http://btlbsmrau.org
Additional affiliations
July 2019 - July 2021
Bangabandhu Sheikh Mujibur Rahman Agricultural University
Position
  • Managing Director
June 2019 - present
Bangladesh Academy of Sciences
Position
  • Fellow
Description
  • Elected as the Fellows of BAS
September 2017 - June 2018
West Virginia University
Position
  • Fulbright Visiting Scholar
Education
September 2017 - June 2018
West Virginia University
Field of study
  • Molecular Plant Pathology
June 2015 - July 2015
Gifu University
Field of study
  • Bioactive natural products
January 2013 - June 2014
Queen Mary, University of London
Field of study
  • Leadership in Higher Education

Publications

Publications (525)
Article
Full-text available
Enterococcus faecalis is associated with streptococcosis like infection in fish. A whole-genome sequence study was conducted to investigate the virulence factor and antibiotic-resistance genes in three fish pathogenic E. faecalis. Genomic DNA was extracted from three strains of E. faecalis isolated from streptococcosis infected Nile tilapia (strain...
Article
Full-text available
We previously reported that SARS-CoV-2 infection reduces human nasopharyngeal commensal microbiomes (bacteria, archaea and commensal respiratory viruses) with inclusion of pathobionts. This study aimed to assess the possible changes in the abundance and diversity of resident mycobiome in the nasopharyngeal tract (NT) of humans due to SARS-CoV-2 inf...
Chapter
Full-text available
Drought, salinity, waterlogging, and extreme temperatures are major abiotic stresses that impact on the growth and yield of crop plants, including wheat. These stresses pose significant negative impacts on the photosynthetic process as well as other physiological and biochemical functions, which ultimately decrease wheat yield. This book chapter ai...
Article
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On July 23, 2022 the World Health Organization (WHO) has announced the Monkeypox disease (MPXD) as a worldwide public health issue. This study conducts a systematic review and meta-analysis to determine the overall case fatality rate (CFR) of MPXD worldwide during 1970-2022. The tenuretracked MPXD outbreaks associated with CFR were calculated based...
Article
Full-text available
Jackfruit ( Artocarpus heterophyllus Lam.) is the national fruit of Bangladesh and produces fruit in the summer season only. However, jackfruit is not commercially grown in Bangladesh because of an extremely high variation in fruit quality, short seasonal fruiting (June-August) and susceptibility to abiotic stresses. Conversely, a year-round high y...
Article
Colorectal cancer is the third most life-threatening cancer in the western countries. For the treatment, several chemotherapeutic drugs are using those that have severe side effects on the patient. So, finding alternative drugs is important. In the present research antimycin A was selected to evaluate the anticancer properties on the HCT-116 colore...
Article
Full-text available
Global crop yield and food security are being threatened by phytophagous insects. Innovative methods are required to increase agricultural output while reducing reliance on hazardous synthetic insecticides. Using the revolutionary CRISPR-Cas technology to develop insect-resistant plants appears to be highly efficient at lowering production costs an...
Chapter
Food security for the growing world population can be affected by many different socio-economic and food production variables including pest outbreaks. Plant disease epidemics historically played a significant role in the starvation and displacement of the world population. Despite huge progress made by researchers in managing diseases of staple co...
Article
Full-text available
Streptococcosis is one of the major threats to Nile tilapia (Oreochromis niloticus) in most regions of the world. Recently, Enterococcus faecalis has been widely reported to be involved in streptococcosis in O. niloticus in Asia and Africa. This study aimed to isolate beneficial marine bacteria to evaluate their effects on growth, hematological par...
Article
Full-text available
Magnaporthe oryzae is one of the most notorious fungal pathogens that causes blast disease in cereals, and results in enormous loss of grain production. Many chemical fungicides are being used to control the pathogen but none of them are fully effective in controlling blast disease. Therefore, there is a demand for the discovery of a new natural bi...
Preprint
Full-text available
Plant diseases are among the major factors affecting plant productivity. Biological control of plant diseases is preferred over chemical control as it is environment-friendly, cost-effective, and sustainable. Among many microbes capable of providing biological control of plant diseases, probiotic Bacillus species are most promising as they can surv...
Article
Full-text available
The presence of highly poisonous arsenic (As) elements in food concerns humans and animals. In Bangladesh, arsenic-contaminated groundwater is frequently utilized for agricultural irrigation. This is a significant source of arsenic pollution in the human food chain. For the first time, we investigated the presence of total arsenic in various foodst...
Preprint
Full-text available
Salinity is abiotic stress, which causes adverse environmental conditions for rice cultivation. In particular, local aromatic rice cultivation is heavily influenced by soil salinity stress, which has an impact on global food security. This study aimed to screen local aromatic rice genotypes in a hydroponics experiment using Yoshida solutions to eva...
Chapter
Fungal infection causes a significant reduction in both quality and yield in different crop plants. Invasive fungal species cause serious community and health care-acquired infections worldwide. It is essential to precisely detect and identify the pathogenic fungi in the seeds and/or at an early stage of plant growth to reduce the yield losses of c...
Chapter
The emergence of environmental contaminants (ECs) either from natural or anthropogenic sources is considered a critical threat to the various components of the ecosystems. Therefore eco-friendly, innovative, and practical approaches for the remediation of ECs are needed toward sustainable environmental pollution management. Among the innovative tec...
Chapter
Innovative farming practices in the traditional agriculture have significantly been progressed in last 1,000 years. Most of these aboriginal agricultural methodologies were not finely honed. Concurrent improvement of biochemistry and engineering, farming practices were also rapidly improved during the early forty years of the twentieth century. Aft...
Article
Full-text available
We investigated the role of two different plant growth-promoting probiotic bacteria in conferring cadmium (Cd) tolerance in rapeseed (Brassica campestris cv. BARI Sarisha-14) through improving reactive oxygen species scavenging, antioxidant defense, and glyoxalase system. Soil, as well as seeds of rapeseed, were separately treated with probiotic ba...
Chapter
Sugarcane is an economically important crop plant under the family of Poaceae. It provides approximately 80% of sugar required for human consumption in the world. It is also used as a raw substance for bioethanol production that is a renewable energy source alternative to hazardous fossil fuels. However, various biotic stresses caused by insects, a...
Article
Full-text available
Multiple bacteria under Streptococcus, Enterococcus and Lactococcus genera are considered to be associated with Streptococcosis. This study was conducted to develop and evaluate the effectiveness of whole cell formalin killed vaccine prepared from E. faecalis, E. hirae and E. faecium against the streptococcosis in Nile tilapia. To develop the candi...
Article
The coupling of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas RNA-programmable nucleases with nucleic acid detection platforms has brought radical changes to the field of disease diagnosis. Recently, Sánchez et al. developed a simple, rapid, highly sensitive, precise, and in-field deployable point-of-care (POC) and point-of...
Chapter
Selenium (Se) is a metalloid mineral micronutrient required for the healthy survival of humans, animals, archaea, and a few microorganisms. Its importance for plants is still being investigated. Presently, the agriculture sector is facing several challenges including a wide range of environmental stresses such as salinity, drought, extreme heat and...
Book
Full-text available
Crop plants growing under field conditions are constantly exposed to various abiotic and biotic stress factors leading to decreased yield and quality of produce. In order to achieve sustainable development in agriculture and to increase agricultural production for feeding an increasing global population, it is necessary to use ecologically compatib...
Preprint
Full-text available
Background: Plant probiotic bacteria enhance growth and yield of crop plant when applied in appropriate time and dose. Two rice probiotic bacteria, Paraburkholderia fungorum strain BRRh-4 and Delftia sp. strain BTL-M2 promote growth and yield of plants. However, no information is available on application of these two bacteria on growth, yield, and...
Article
Full-text available
Food waste management is a critical environmental issue in many developing countries, including Bangladesh, due to unplanned food waste disposal and lack of dedicated food waste legislation. In those countries, a significant amount of food waste is discarded to the environment rather than being recycled. In Bangladesh, food waste is traditionally o...
Preprint
Full-text available
Global crop yield and food security are being threatened by phytophagous insects. Innovative methods are required to increase agricultural output while reducing reliance on hazardous synthetic insecticides. It appears to be quite effective at reducing production costs and boosting farm profitability to use the ground-breaking CRISPR-Cas technology...
Chapter
Plant growth-promoting rhizobacteria (PGPR) are regarded as the biostimulants for plant growth and development. These bioagents are also used as the bioprotectants of plants to combat the biotic and abiotic stresses in plants. The diverse mechanisms of the PGPR for regulating plant nutrition and defending the stressful conditions of plant growth ar...
Article
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Summary Efficient pathogen diagnostics and genotyping methods enable effective disease management and breeding, improve crop productivity and ensure food security. However, current germplasm selection and pathogen detection techniques are laborious, time‐consuming, expensive, and not easy to mass‐scale application in the field. Here, we optimized a...
Chapter
Fungal pathogens are one of the major threats to global food safety and security. Chemical fungicides are highly effective and convenient for their management. Unfortunately, indiscriminate use of fungicides poses serious threats on ecosystem as well as on every kind of living organism dwelling on the earth. At present, Bacillus-based biotic stress...
Chapter
Full-text available
Magnaporthe oryzae is one of the most destructive fungal pathogen causing blast diseases in at least 50 grass species including wheat and rice. Although there has been comprehensive study on the fungicidal control of blast diseases, the development of pathogen resistance to commercially available products makes this approach inefficient. Novel stra...
Article
Full-text available
Drought is one of the most destructive abiotic stresses that impact the growth, physiology, yield, and nutritional quality of seeds of crop plants. In modern agriculture, the use of nanoparticles can be beneficial due to their large surface area and higher potentiality to enter into the plant leaf during foliar application. This study aims to evalu...
Article
Full-text available
The COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has created an urgent global situation. Therefore, it is necessary to identify the differentially expressed genes (DEGs) in COVID-19 patients to understand disease pathogenesis and the genetic factor(s) responsible for inter-individual variability and dis...
Article
Full-text available
Wheat blast caused by the Magnaporthe oryzae Triticum (MoT) pathotype is one of the most damaging fungal diseases of wheat. During the screening of novel bioactive secondary metabolites, we observed two marine secondary metabolites, bonactin and feigrisolide C, extracted from the marine bacteria Streptomyces spp. (Act 8970 and ACT 7619), remarkably...
Article
Full-text available
In this study, the feasibility of two heterogeneous catalysis (non-Fenton heterogeneous catalysis and catalytic ozonation) was evaluated for the oxidative transformation of the fungicide procymidone and its major metabolite (3,5-dichloroaniline; 3,5-DCA) under a pilot lab experiment. Among the studied treatments, only H2O2 or O3 significantly oxidi...
Preprint
Full-text available
Faba bean ( Vicia faba L.), a promising grain legume, widely grown in central and northern part of Bangladesh. Disease symptoms resembling to collar and root rot was observed in an experimental field of Bangladesh Agricultural University, Mymensingh, Bangladesh. Disease incidence was ranged between 11–19%. Water-soaked sunken lesions were appeared...
Article
Fusarium head blight (FHB) is a worldwide devastating disease of small grain cereals and Fusarium graminearum species complex (FGSC) is the major pathogen causing the disease. The epidemics of FHB lead to the reduction of grain yield and economic losses. Additionally, mycotoxins produced by the FHB pathogens are hazardous to the health of human and...
Article
Magnaporthe oryzae, the causal agent of blast diseases, is a destructive filamentous fungus that infects many plants including most economically important food crops, rice, wheat, pearl millet and finger millet. M. oryzae has numerous pathotypes because of its high host-specificity in the field. The Oryza pathotype (MoO) of M. oryzae is the most de...
Article
Full-text available
Soil salinity has emerged as a serious issue for food security due to global climate change. It is estimated that currently about 62 million hectares or 20 percent of the world’s irrigated land is affected by salinity. Salinity is a serious problem in the coastal areas of Bangladesh. Isolation of salt-tolerant plant growth-promoting bacteria (PGPB)...
Article
Full-text available
Background Mastitis pathogenesis involves a wide range of opportunistic and apparently resident microorganims including bacteria, viruses and archaea. In dairy animals, microbes reside in the host, interact with environment and evade the host immune system, providing a potential for host-tropism to favor mastitis pathogenesis. To understand the hos...
Article
Full-text available
This pilot investigation aimed to evaluate the removal efficiency and the underlying biocatalytic pathways of immobilized fungal laccase during the oxidative biotransformation of a non-phenolic metabolite, 3,5-dichloroaniline (3,5-DCA) derived from dicarboximide fungicides. The maximum loading of laccase on the microporous support surfaces could re...
Preprint
Full-text available
Magnaporthe oryzae is one of the most notorious fungal pathogens that causes blast disease in cereals and results in enormous loss of grain production. Many chemical fungicides are being used to control the pathogen but none of them are effective against blast disease. Thus, there is a demand to discover potential and safe natural biofungicides to...
Article
Full-text available
The COVID-19 threatens nearly most of the world's population with a significant mortality rate over the last 2 years. The main cause of death in those infected with SARS-CoV-2 is acute lungs infection, which is brought about by increased inflammatory activity, oxidative anxiety, and inflammatory reactions in the respiratory tract. To date, there is...
Article
Full-text available
Protein kinases (PKs), being key regulatory enzymes of a wide range of signaling pathways, are potential targets for antifungal agents. Wheat blast disease, caused by Magnaporthe oryzae Triticum (MoT), is an existential threat to world food security. During the screening process of natural metabolites against MoT fungus, we find that two protein ki...
Article
Full-text available
The application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on humans and the environment. Therefore, alternative approaches for crop protection through microbial or microbe‐originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease cause...
Article
Citation: Paul, S.K.; Chakraborty, M.; Rahman, M.; Gupta, D.R.; Mahmud, N.U.; Rahat, A.A.M.; Sarker, A.; Hannan, M.A.; Rahman, M.M.; Akanda, A.M.; et al. Marine Natural Product Antimycin A Suppresses Wheat Blast Disease Caused by Magnaporthe oryzae Triticum. J. Fungi 2022, 8, 618. https://doi.
Preprint
Wheat, the most important food crop, is threatened by a blast disease pandemic. Here, we show that a clonal lineage of the wheat blast fungus recently spread to Asia and Africa following two independent introductions from South America. Through a combination of genome analyses and laboratory experiments, we show that the decade-old blast pandemic l...
Article
The in vitro compatibility of the entomopathogenic fungus, Cladosporium cladosporioides BOU1, with the crude extract of three plants viz. Calotropis gigantea, Vitex negundo and Carissa macrocarpa at a concentration of 1% and 2% was investigated. The compatibility of the fungal isolate with the plant extracts was calculated using the biological inde...
Chapter
Full-text available
Abstract Pesticides are biological or chemical agents that can protect plants from various pests including insects and pathogens. Injudicious use of chemical pesticides has led to severe health hazards, environmental pollution, and increased cost of production. Thus, novel approaches are necessary to protect the crop plants with minimal or no delet...
Preprint
Full-text available
Application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on human and environment. Therefore, alternative approaches for crop protection through microbial or microbe originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease caused by Magn...
Article
Full-text available
Wheat blast, caused by the Magnaporthe oryzae Triticum (MoT) pathotype, threatens wheat production in many countries, including Bangladesh. Traditional fungicides are ineffective in combating this pathogen, and no resistant wheat variety is available. This study investigated the mechanism of wheat blast suppression by a nanostructured TiO2 nanocata...
Preprint
Full-text available
Application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on human and environment. Therefore, alternative approaches for crop pro-tection through microbial or microbe originated pesticides have been gaining momentum. Wheat blast is a destructive fungal disease caused by Mag...
Article
Background Plant triterpenoids are major sources of nutraceuticals that provide many health benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in many fruits and vegetables, which is highly investigated for its pharmacological effect and benefit to human health. Purpose This systematic review critically discu...
Chapter
Full-text available
Nanotechnology is emerging as a tool for improving crop production by enhancing the tolerance of crop plants to various stresses. Various kinds of nanoparticles (1–100 nm in size) show high performances in genetic gain, nutrient security, soil improvement, and sustainability in crop production. The promise of nanotechnology in crop production is di...
Preprint
Full-text available
Artemisia annua L. produces artemisinin (qinghaosu), which is inhibitory against malarial parasite, Plasmodium falciparum . Genetic engineering is thought to be one of the most reasonable approaches to enhance the production of artemisinin by A. annua plant. This study aimed to clone and investigate a growth regulatory cytochrome p450 gene from A....
Article
Full-text available
A 2NvS chromosomal segment carrying bread wheat variety, BARI Gom 33 (‘BG33’), showed tolerance to terminal heat stress and higher yield over a heat-tolerant non-2NvS BARI Gom 26 (‘BG26’) and a heat-susceptible Pavon 76 (‘Pavon’). This study aimed to ascertain the potential of the 2NvS ‘BG33’ in terminal heat-induced oxidative stress tolerance comp...
Preprint
Full-text available
SARS-CoV-2 continues to spread and evolve worldwide, despite intense efforts to develop multiple vaccines and therapeutic options against COVID-19. Moreover, the precise role of SARS-CoV-2 in the pathophysiology of the nasopharyngeal tract (NT) is still unfathomable. Therefore, we used the machine learning methods to analyze 22 RNA-seq datasets fro...