Titilope Titi OlanipekunBrigham and Women's Hospital/Harvard Medical School
Titilope Titi Olanipekun
MD, MPH
About
104
Publications
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Introduction
Publications
Publications (104)
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis affecting the spine, presenting a considerable morbidity risk. Although evidence consistently indicates an elevated risk of ischemic heart disease among AS patients, debates persist regarding the likelihood of these patients developing left ventricular dysfunction (LVD). Our investigat...
Summary
Background Lower respiratory infections (LRIs) are a major global contributor to morbidity and mortality. In 2020–21,
non-pharmaceutical interventions associated with the COVID-19 pandemic reduced not only the transmission of
SARS-CoV-2, but also the transmission of other LRI pathogens. Tracking LRI incidence and mortality, as well as the
p...
Background
Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of D...
Background
Impella is an advanced ventricular assist device frequently used as a bridge to heart transplantation. The association of Impella with increased rates of gout flares has not been studied. Our primary aim is to determine the rates of gout flares in patients on Impella support.
Methodology
A retrospective study was conducted between Janua...
Background
We aim to determine the added value of carotid intima-media thickness (cIMT) in stroke risk assessment for hypertensive Black adults.
Methods
We examined 1647 participants with hypertension without a history of cardiovascular disease, from the Jackson Heart Study. Cox regression analysis estimated hazard ratios (HR) for incident stroke...
OBJECTIVES
Traditional journal clubs have been shown to be insufficient in improving residents’ scholarly productivity, often due to the inability to sustain residents’ interest and participation. Additionally, the 2019 novel coronavirus (COVID-19) pandemic restrictions caused a decline in academic scholarly productivity across residency programs....
Background
Impella is an advanced ventricular assist device frequently used as a bridge to heart transplantation. The association of Impella with increased rates of gout flares has not been studied. Our primary aim is to determine the rates of gout flares in patients on Impella support.
Methodology
A retrospective study was conducted between Janua...
Objectives:
To evaluate the 30-day postoperative mortality and palliative care consultations in patients that underwent surgical procedures in the United States before and after Medicare Access and Children's Health Insurance Program Reauthorization Act (MACRA) implementation.
Design:
Retrospective, Observational cohort study.
Setting:
Seconda...
Background:
Overall inferior vena cava filter (IVCF) utilization has decreased in the United States since the 2010 US Food and Drug Administration (FDA) safety communication. The FDA renewed this safety warning in 2014 with additional mandates on reporting IVCF-related adverse events. We evaluated the impact of the FDA recommendations on IVCF plac...
Background
Although there has been a decrease in the incidence of ST‐segment–elevation myocardial infarction (STEMI) in the United States, this trend might be stagnant or increasing in young women. We assessed the trends, characteristics, and outcomes of STEMI in women aged 18 to 55 years.
Methods and Results
We identified 177 602 women aged 18 to...
Unlabelled:
High safety-net burden hospitals (HBHs) treating large numbers of uninsured or Medicaid-insured patients have generally been linked to worse clinical outcomes. However, limited data exist on the impact of the hospitals' safety-net burden on in-hospital cardiac arrest (IHCA) outcomes in the United States.
Objectives:
To compare the di...
Introduction: There is limited data on the gender differences in the trend of hospitalizations related to PAH and associated outcomes in the US
Methods: We queried the National Inpatient Sample from 2010 to 2019 to identify PAH admissions using international classification of diseases (ICD) codes 416.0 (ICD-9) and I27.0 (ICD-10)
Results: 20,513 hos...
Introduction: Liver cirrhosis affects an estimated 1 in 400 adults in the US with significant morbidity and mortality. There is limited data on the incidence and outcomes of in-hospital cardiac arrest (IHCA) in liver cirrhosis-related hospitalizations.
Methods: Using the appropriate international classification of disease codes, we queried the nati...
Background: Cardiac arrest is a known complication of Pulmonary arterial hypertension (PAH) often due to acute right heart failure and arrhythmias. However, data on trends in the incidence and in-hospital outcomes of in-hospital cardiac arrest (IHCA) among PAH-related hospitalizations in the US is limited.
Hypothesis: IHCA incidence has declined an...
Background: Safety net hospitals treat a large burden of uninsured, or Medicaid insured patients, and have been linked to worse outcomes across several medical and surgical conditions. Currently, there is limited data on the effect of safety net burden on outcomes of inpatient cardiopulmonary resuscitation (CPR) for patients that suffered in-hospit...
Introduction: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often used in patients with cardiogenic shock. However, this strategy can lead to left ventricular (LV) distention, thus compromising myocardial recovery. Therefore, concomitant LV unloading with an Impella device (Abiomed, Danvers, MA) has gained a wide interest to promote...
Contemporary data on catheter-directed thrombolysis (CDT) utilization trends and associated hospital outcomes in pulmonary embolism (PE) n the US is limited. Using the nationwide inpatient sample database, we identified patients hospitalized for acute PE treated with CDT from January 1, 2008, to December 31, 2018. Cochrane-Armitage test was used to...
Importance:
Cardiogenic shock (CS) is a recognized complication of peripartum cardiomyopathy (PPCM) associated with poor prognosis. Although racial and ethnic disparities have been described in the occurrence and outcomes of PPCM, it is unclear if these disparities persist among patients with PPCM and CS.
Objectives:
To evaluate the temporal tre...
Background
Rothia species are known to cause dental caries and periodontal disease, and infrequently cause native or prosthetic valve endocarditis mostly in immunocompromised persons. With an increasing use of implantable cardiac devices, early clinical suspicion and a rapid diagnosis of endocarditis is essential for optimal treatment to reduce com...
Background:
Data on the incidence, predictors, and outcomes of sudden cardiac arrest (SCA) in the immediate post-percutaneous coronary intervention (PCI) period for ST-elevation myocardial infarction (STEMI) are limited.
Objectives:
The study aimed to investigate the trends and predictors of SCA occurring within 48 h post PCI for STEMI.
Methods...
In-hospital acute kidney injury (IH-AKI) has been reported in a significant proportion of patients with COVID-19 and is associated with increased disease burden and poor outcomes. However, the mechanisms of injury are not fully understood. We sought to determine the significance of race on cardiopulmonary outcomes and in-hospital mortality of hospi...
Introduction: There is limited data on racial disparities in the outcomes of PPCM complicated by cardiogenic shock
Methods: We identified 5,838 patients hospitalized with the PPCM and CS from the 2007 to 2018 National Inpatient Sample, of which 2214 (38%) were White, 3006 (51.4%) Black, and 618 (11%) Hispanic. Cochrane Armitage test and multivariab...
Background:
There is limited data on the difference in the clinical characteristics and outcomes of patients with severe coronavirus disease 2019 (COVID-19) infection in the summer compared to the fall surge.
Aim:
To compare the sociodemographic, clinical characteristics, and outcomes among mechanically ventilated patients with severe COVID-19 i...
Introduction
The timing of sudden cardiac arrest (SCA) after myocardial infarction (MI) has been a subject of research because of the impact on preventive strategies. Currently, there is limited data on the risk of SCA in the immediate post revascularization period (≤48 h) in non-ST segment elevation myocardial infarction (NSTEMI).
Methods
We retr...
Introduction
We surveyed a cohort of patients who recovered from severe SARS-CoV-2 infection to determine the COVID-19 vaccination rate. We also compared the willingness to accept the vaccine before and after its availability to assess changes in perception and attitude towards vaccination.
Materials and Methods
Recovered patients with severe hypo...
Purpose
: To determine racial differences in intensive care unit (ICU) mortality outcomes among mechanically ventilated patients with severe coronavirus disease 2019 (COVID-19) infection in a safety net hospital.
Methods
: We retrospectively analyzed a cohort of patients ≥ 18 years old with confirmed severe acute respiratory syndrome-CoV-2 disease...
Objectives
This study assessed the temporal trends in the incidence of ischemic stroke among patients hospitalized with takotsubo cardiomyopathy (TCM) stratified by the subtypes of ischemic stroke (cardioembolic versus thrombotic).Predictors of each stroke subtype, the association with atrial fibrillation (AF), the occurrence of ventricular fibrill...
Background
Each July, teaching hospitals in the United States experience an influx of new resident and fellow physicians. It has been theorized that this occurrence may be associated with increased patient mortality, complication rates, and health care resource use, a phenomenon known as the “July effect.”
Objective
To assess the existence of a Ju...
Proximal left main stenting in symptomatic patients with flow-limiting stenosis is an alternative revascularization strategy in individuals with low syntax score and high operative risk. Stent dislodgement is associated with adverse cardiovascular events and retrieval of fully deployed stents is generally prohibited as it increases the risk of seve...
Background
Coronavirus disease (COVID-19) disproportionately affects African Americans, and they tend to experience more severe course and adverse outcomes. Using a simple and validated instrument of depression screening, we evaluated the incidence and severity of major depression among African American patients within 90 days of recovery from seve...
The CDC regularly updates guidance on COVID-19 testing for inpatients and hospital discharges to nursing homes and long-term care facilities. However, most long-term care facilities require a negative COVID-19 test result before accepting patients discharged from the hospital which directly contravenes the CDC guidelines. Due to delays in COVID-19...
Background:
In this study, we investigated the temporal trends in the prevalence and prognostic implication of atrial fibrillation (AF) in patients with light-chain cardiac amyloidosis (AL-CA)
Methods:
We identified 3030 patients with AL-CA from the 2015 to 2017 National Inpatient Sample, of which 1,577 (52%) had AF. We used trend analysis to as...
Case series
Patients: Male, 71-year-old • Female, 58-year-old
Final Diagnosis: Pulmonary barotrauma
Symptoms: Pneumomediastinum
Medication: —
Clinical Procedure: Chest tube
Specialty: Critical Care Medicine
Objective
Unusual clinical course
Background
Invasive mechanical ventilation can cause pulmonary barotrauma due to elevated transpulmonary pr...
BACKGROUND
There is a lack of data on the clinical outcomes in patients with native valve infective endocarditis (NVIE) and diabetes mellitus (DM).
AIM
To investigate (1) trends in the prevalence of DM among patients with NVIE; and (2) the impact of DM on NVIE outcomes.
METHODS
We identified 76385 with NVIE from the 2004 to 2014 National Inpatien...
Introduction
Coronavirus disease 2019 (COVID‐19) has become a major global crisis. Preliminary reports have, in general, indicated worse outcomes in diabetes mellitus (DM) patients, but the magnitude of cardiovascular (CV) complications in this subgroup has not been elucidated.
Methods
We included 142 patients admitted with laboratory‐confirmed CO...
Background: Depression is considered an independent risk factor for coronary artery disease. Post-myocardial infarction (PMI) depression, is an increasingly recognized clinical entity with a prevalence of 10%. Compared with other ethnic groups, African Americans (AA) are more likely to be depressed and have higher coronary artery disease (CAD) burd...
Introduction:
Assessment of how medical residents learn and the impact on standardized test performance is important for effective training. Kolb's learning study inventory categorizes learning into accommodating, assimilating, converging and diverging based on the four stages of learning: active experimentation, abstract conceptualization, concre...
Background:
Evidence suggests that annual influenza vaccination may prevent acute heart failure exacerbation episodes and improve survival.
Objective:
Determine the influenza vaccination rate among African American patients with heart failure and identify predictors of uptake.
Methods:
African American patients with heart failure were recruite...
INTRODUCTION
Gallbladder (GB) stasis is highly prevalent in the general population, especially amongst females. It is also one of the most common gastrointestinal causes of hospital admission. A limited number of studies have shown no association between vitamin D levels and gallstone disease in the general population, despite an established associ...
INTRODUCTION
Diverticula disease historically has been known to be a disease of the elderly with estimated prevalence greater than 50% in people ages 60 and above. The healthcare costs associated with impact of diverticular disease is estimated at $3 billion per year. Diverticular disease is one of the commonest reasons for gastroenterology visit y...
INTRODUCTION
The mediating effect of liver disease on cardiac diseases has not been comprehensively outlined in the medical literature. Liver disease can increase your risk of heart disease which remains the leading cause of death in the United States. In this study, we looked at the overview of the mediating effect of liver disease on patients dia...
Gastrointestinal Kaposi sarcoma (GI-KS) is the most common extra-cutaneous site of KS in HIV/AIDS, and the majority (75%) of affected patients are asymptomatic. GI-KS rarely occurs in the absence of cutaneous lesions. Opportunistic GI infections in HIV/AIDS and GI-KS can present with similar symptoms especially diarrhea, creating a diagnostic chall...
Introduction
Obstructive sleep apnea (OSA) is often associated with depression. Identifying and treating depression improve the quality of life of patients with OSA. African Americans (AA) tend to have severe OSA and poor access to care. OSA management in the primary care setting has recently gained traction to improve outcomes. There is a paucity...
Bladder necrosis and perforation is a rare and life-threatening medical emergency. Risk factors include trauma, malignancy, previous surgery and/or radiation therapy and diabetes mellitus. Signs, symptoms, and imaging findings are often obscure making the diagnosis difficult. Urinary tract infection is common in end-stage renal disease (ESRD) patie...
The study by Au et al (1), published in a recent issue of Critical Care Medicine, provides a thorough assessment of family participation in ICU rounds. The society for critical care medicine recommends that family members of critically ill patients be offered the opportunity to participate in interdisciplinary team rounds in order to increase famil...