Titilope Titi Olanipekun

Clinical Research

Background: Overall inferior vena cava filter (IVCF) utilization has decreased in the United States since the 2010 US Food and Drug Administration (FDA) safety communication. The FDA renewed this safety warning in 2014 with additional mandates on reporting IVCF-related adverse events. We evaluated the impact of the FDA recommendations on IVCF plac...

Background Although there has been a decrease in the incidence of ST‐segment–elevation myocardial infarction (STEMI) in the United States, this trend might be stagnant or increasing in young women. We assessed the trends, characteristics, and outcomes of STEMI in women aged 18 to 55 years. Methods and Results We identified 177 602 women aged 18 to...

Unlabelled: High safety-net burden hospitals (HBHs) treating large numbers of uninsured or Medicaid-insured patients have generally been linked to worse clinical outcomes. However, limited data exist on the impact of the hospitals' safety-net burden on in-hospital cardiac arrest (IHCA) outcomes in the United States. Objectives: To compare the di...

Contemporary data on catheter-directed thrombolysis (CDT) utilization trends and associated hospital outcomes in pulmonary embolism (PE) n the US is limited. Using the nationwide inpatient sample database, we identified patients hospitalized for acute PE treated with CDT from January 1, 2008, to December 31, 2018. Cochrane-Armitage test was used to...

Importance: Cardiogenic shock (CS) is a recognized complication of peripartum cardiomyopathy (PPCM) associated with poor prognosis. Although racial and ethnic disparities have been described in the occurrence and outcomes of PPCM, it is unclear if these disparities persist among patients with PPCM and CS. Objectives: To evaluate the temporal tre...

Background: Rothia species are known to cause dental caries and periodontal disease, and infrequently cause native or prosthetic valve endocarditis mostly in immunocompromised persons. With an increasing use of implantable cardiac devices, early clinical suspicion and a rapid diagnosis of endocarditis is essential for optimal treatment to reduce co...

Background: Data on the incidence, predictors, and outcomes of sudden cardiac arrest (SCA) in the immediate post-percutaneous coronary intervention (PCI) period for ST-elevation myocardial infarction (STEMI) are limited. Objectives: The study aimed to investigate the trends and predictors of SCA occurring within 48 h post PCI for STEMI. Methods...

In-hospital acute kidney injury (IH-AKI) has been reported in a significant proportion of patients with COVID-19 and is associated with increased disease burden and poor outcomes. However, the mechanisms of injury are not fully understood. We sought to determine the significance of race on cardiopulmonary outcomes and in-hospital mortality of h...

Background: There is limited data on the difference in the clinical characteristics and outcomes of patients with severe coronavirus disease 2019 (COVID-19) infection in the summer compared to the fall surge. Aim: To compare the sociodemographic, clinical characteristics, and outcomes among mechanically ventilated patients with severe COVID-19 i...

Introduction The timing of sudden cardiac arrest (SCA) after myocardial infarction (MI) has been a subject of research because of the impact on preventive strategies. Currently, there is limited data on the risk of SCA in the immediate post revascularization period (≤48 h) in non-ST segment elevation myocardial infarction (NSTEMI). Methods We retr...

Introduction We surveyed a cohort of patients who recovered from severe SARS-CoV-2 infection to determine the COVID-19 vaccination rate. We also compared the willingness to accept the vaccine before and after its availability to assess changes in perception and attitude towards vaccination. Materials and Methods Recovered patients with severe hypo...

Purpose : To determine racial differences in intensive care unit (ICU) mortality outcomes among mechanically ventilated patients with severe coronavirus disease 2019 (COVID-19) infection in a safety net hospital. Methods : We retrospectively analyzed a cohort of patients ≥ 18 years old with confirmed severe acute respiratory syndrome-CoV-2 disease...

Objectives This study assessed the temporal trends in the incidence of ischemic stroke among patients hospitalized with takotsubo cardiomyopathy (TCM) stratified by the subtypes of ischemic stroke (cardioembolic versus thrombotic).Predictors of each stroke subtype, the association with atrial fibrillation (AF), the occurrence of ventricular fibrill...

Background Each July, teaching hospitals in the United States experience an influx of new resident and fellow physicians. It has been theorized that this occurrence may be associated with increased patient mortality, complication rates, and health care resource use, a phenomenon known as the “July effect.” Objective To assess the existence of a Ju...

Proximal left main stenting in symptomatic patients with flow-limiting stenosis is an alternative revascularization strategy in individuals with low syntax score and high operative risk. Stent dislodgement is associated with adverse cardiovascular events and retrieval of fully deployed stents is generally prohibited as it increases the risk of seve...

Background Coronavirus disease (COVID-19) disproportionately affects African Americans, and they tend to experience more severe course and adverse outcomes. Using a simple and validated instrument of depression screening, we evaluated the incidence and severity of major depression among African American patients within 90 days of recovery from seve...

The CDC regularly updates guidance on COVID-19 testing for inpatients and hospital discharges to nursing homes and long-term care facilities. However, most long-term care facilities require a negative COVID-19 test result before accepting patients discharged from the hospital which directly contravenes the CDC guidelines. Due to delays in COVID-19...

Background: In this study, we investigated the temporal trends in the prevalence and prognostic implication of atrial fibrillation (AF) in patients with light-chain cardiac amyloidosis (AL-CA) Methods: We identified 3030 patients with AL-CA from the 2015 to 2017 National Inpatient Sample, of which 1,577 (52%) had AF. We used trend analysis to as...

BACKGROUND Invasive mechanical ventilation can cause pulmonary barotrauma due to elevated transpulmonary pressure and alveolar rupture. A significant proportion of COVID-19 patients with acute respiratory distress syndrome (ARDS) will require mechanical ventilation. We present 2 interesting cases that demonstrate the possibility of COVID-19-associa...

BACKGROUND There is a lack of data on the clinical outcomes in patients with native valve infective endocarditis (NVIE) and diabetes mellitus (DM). AIM To investigate (1) trends in the prevalence of DM among patients with NVIE; and (2) the impact of DM on NVIE outcomes. METHODS We identified 76385 with NVIE from the 2004 to 2014 National Inpatien...

Introduction Coronavirus disease 2019 (COVID‐19) has become a major global crisis. Preliminary reports have, in general, indicated worse outcomes in diabetes mellitus (DM) patients, but the magnitude of cardiovascular (CV) complications in this subgroup has not been elucidated. Methods We included 142 patients admitted with laboratory‐confirmed CO...

Background: Depression is considered an independent risk factor for coronary artery disease. Post-myocardial infarction (PMI) depression, is an increasingly recognized clinical entity with a prevalence of 10%. Compared with other ethnic groups, African Americans (AA) are more likely to be depressed and have higher coronary artery disease (CAD) burd...

Introduction: Assessment of how medical residents learn and the impact on standardized test performance is important for effective training. Kolb's learning study inventory categorizes learning into accommodating, assimilating, converging and diverging based on the four stages of learning: active experimentation, abstract conceptualization, concre...

Background: Evidence suggests that annual influenza vaccination may prevent acute heart failure exacerbation episodes and improve survival. Objective: Determine the influenza vaccination rate among African American patients with heart failure and identify predictors of uptake. Methods: African American patients with heart failure were recruite...

Gastrointestinal Kaposi sarcoma (GI-KS) is the most common extra-cutaneous site of KS in HIV/AIDS, and the majority (75%) of affected patients are asymptomatic. GI-KS rarely occurs in the absence of cutaneous lesions. Opportunistic GI infections in HIV/AIDS and GI-KS can present with similar symptoms especially diarrhea, creating a diagnostic chall...

Introduction Obstructive sleep apnea (OSA) is often associated with depression. Identifying and treating depression improve the quality of life of patients with OSA. African Americans (AA) tend to have severe OSA and poor access to care. OSA management in the primary care setting has recently gained traction to improve outcomes. There is a paucity...

Bladder necrosis and perforation is a rare and life-threatening medical emergency. Risk factors include trauma, malignancy, previous surgery and/or radiation therapy and diabetes mellitus. Signs, symptoms, and imaging findings are often obscure making the diagnosis difficult. Urinary tract infection is common in end-stage renal disease (ESRD) patie...

The study by Au et al (1), published in a recent issue of Critical Care Medicine, provides a thorough assessment of family participation in ICU rounds. The society for critical care medicine recommends that family members of critically ill patients be offered the opportunity to participate in interdisciplinary team rounds in order to increase famil...

Background: African Americans have a higher burden of atherosclerotic risk factors and higher rates of incident cardiovascular disease (CVD) compared to other race/ethnic groups in the US. However, studies have demonstrated a high prevalence of a coronary artery calcium (CAC) score of 0 in this population. We hypothesize that carotid intima-media t...

Exertional rhabdomyolysis from sickle cell trait has been documented. Also, cases of rhabdomyolysis from the use of weight loss supplements in the setting of sickle cell trait and exertion have been described. However, the role of sickle cell trait in non-exertional rhabdomyolysis is not clear. We present a case of severe non-exertional rhabdomyoly...

The American Journal of Gastroenterology is published by Springer Nature on behalf of the American College of Gastroenterology (ACG). Ranked the #1 clinical journal covering gastroenterology and hepatology*, The American Journal of Gastroenterology (AJG) provides practical and professional support for clinicians dealing with the gastroenterological...

Severe immunosuppression and the presence of opportunistic infections in human immunodeficiency virus/acquired immunodeficiency syndrome are strongly associated with incidence of venous thromboembolism especially deep venous thrombosis and pulmonary embolism (PE). The co-occurrence of 2 diseases with similar clinical presentation can pose diagnosti...

http://bmjopen.bmj.com/content/7/6/e015735.responses#re-risk-of-death-among-users-of-proton-pump-inhibitors-a-longitudinal-observational-cohort-study-of-united-states-veterans

Tanzanian men who have sex with men (MSM) experience HIV disparity and are disproportionately vulnerable to psychosocial health problems together called SAVID (Substance abuse, childhood and adolescent sexual Abuse [CSA], anti-gay Violence, Internalized homonegativity [IH], and Depression). We applied syndemic theory to assess additive effects of t...

Background: In the extremely homophobic conditions in Tanzania and other countries in sub-Saharan Africa (SSA), men who have sex with men (MSM) experience disproportionate amounts of both HIV infection and psychosocial health problems, but no research has been conducted to examine the synergistic or additive effects of these adversities on their ex...

The posting and transfer of health workers and managers receives little policy and research attention in global health. In Nigeria, there is no national policy on posting and transfer in the health sector. We sought to examine how the posting and transfer of frontline primary health care (PHC) workers is conducted in four states (Lagos, Benue, Nasa...

BACKGROUND Tuberculosis (TB) is endemic in Nigeria due mainly to the high burden of HIV/AIDS and especially in Benue state which has the highest prevalence of HIV in Nigeria.Sputum smear examination is of importance in the diagnosis of pulmonary TB and can be smear-positive or negative. In this study, we analyzed the sputum smear results of all pa...

In Nigeria, the shortage of health workers is worst at the primary health care (PHC) level, especially in rural communities. And the responsibility for PHC - usually the only form of formal health service available in rural communities - is shared among the three tiers of government (federal, state, and local governments). In addition, the responsi...