Titilade Kehinde Ayandeyi Teibo

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• Master of Science
• Research Assistant at University of São Paulo

ABSTRACT The invasiveness and low survivability on the part of patients associated with cancer continue to raise global concern. Different approaches have been used in the treatment and restoration of normalcy in cancer patients. However, most of the therapeutic strategies employed are challenged with high cost, low efficacy, high toxicity, and mu...

(1) Background: Tuberculosis remains a public health problem in the world. This study evaluated the temporal trends, distribution, and spatial associations of drug-resistant tuberculosis in liberty-deprived populations in the state of Paraná, Brazil. (2) Methods: An ecological study was developed using all cases of drug-resistant tuberculosis in pe...

The impact of COVID-19 is significant in the body system, one of which is the central nervous system (CNS) involved in controlling all aspects of human behavior and coordination. This shows the need to assess from various studies in human and animal models the neurological effects of this virus. Some of the reported effects include loss of taste an...

Background Health risk perception and factors associated with the severity or death from COVID-19 were key elements that influenced individuals' protective behaviors during the pandemic. Understanding these perceptions is crucial for public health guidelines that encourage preventive measures and improve an outbreak response strategy. Thus, this sy...

Background: This study investigated the determinants of COVID-19 mortality and its temporal trends within São Paulo state’s Departamentos Regionais de Saúde (DRS) (health regions) to inform the development of targeted public health interventions. Methods: Utilizing an ecological study design, we analyzed confirmed COVID-19 cases and deaths (Februar...

(1) Background: This study investigated the determinants of COVID-19 mortality and its temporal trends within São Paulo state’s Regional Health Departments (DRS) to inform the development of targeted public health interventions. (2) Methods: Utilizing an ecological study design, we analyzed confirmed COVID-19 cases and deaths (February 2020 – Decem...

In this study, the aim was to comparatively examine the perception of risk for developing severe illness or complications due to COVID-19 among the general population and socially vulnerable populations in Brazil, focusing on uncovering the associated factors that disproportionately impacted people experiencing homelessness and slum dwellers. This...

Background: It is known that leprosy is a socially determined disease, but most studies using spatial analysis have not considered the vulnerabilities present in these territories. Objectives: To measure the association between social vulnerability and the burden of leprosy in the urban space of Cuiabá. Methods: Ecological study, carried out i...

Brazil was heavily impacted by COVID-19 pandemic, which intensified social and health disparities, especially in vulnerable areas such as slums. Therefore, the aim of this study was to investigate which residents of slums in Brazil were most affected by COVID-19 pandemic, with a focus on food insecurity, loss of income, ethnic and racial inequaliti...

This study analyzes the self-perception of mental health of socially vulnerable elderly people during the COVID-19 crisis in Brazil. Conducted across all state capitals from February 2021 to October 2023, it included 366 participants living in various conditions such as camps, street situations, slums, and communities. The average age was 66.7 year...

Objective To assess the evolution of the COVID-19 pandemic in Brazil and its macro-regions, considering disease incidence and mortality rates, as well as identifying territories with still rising disease indices and evaluating vaccine coverage and population adherence to COVID-19 immunization. Methods An ecological study conducted in Brazil with C...

This study evaluated the barriers that interfere with access to diagnosis and treatment of tuberculosis (TB) from the perspective of the patient and health professionals globally. Using the PICo acronym, the question we asked was “What are the barriers that interfere with access to tuberculosis diagnosis and treatment (I) from the perspective of pa...

Background During COVID-19, the number of people experiencing homelessness increased, further exacerbating the violation of basic rights necessary for human survival. Thus, the study aimed to investigate the inequalities associated with income loss and food insecurity among people experiencing homelessness during the COVID-19 pandemic in Brazil. M...

Background The Ricinus genus consists of herbs with one known species, Ricinus communis Linn is commonly referred to as a castor oil plant. This plant is a rapidly developing perennial herb with moderate height, it is also a member of the castor bean family that possesses spiky green fruits. The flowers lack petals and are also monoecious. The frui...

Background With the onset of the COVID-19 pandemic, there has been a discernible amplification of inherent vulnerabilities in the global population, with the most susceptible segments exemplified by the Homeless Population experiencing exacerbated adverse impacts.. This study aims to analyze the intersection of vulnerabilities among homeless popula...

Myrtus communis L. (Family: Myrtaceae) is naturally found in the western part of Asia, Southern Europe, and North Africa. It has been reportedly applied in pharmaceutical industry, traditional medicine, cosmetics, spices, and food. Pubmed, Google scholar, Web of Science, and Scopus were utilized to seek out relevant content concerning the therapeut...

Background: With the onset of the COVID-19 pandemic, there has been a discernible amplification of inherent vulnerabilities in the global population, with the most susceptible segments exemplified by the Homeless Population experiencing exacerbated adverse impacts.. This study aims to analyze the intersection of vulnerabilities among homeless popul...

Background The perception of the risk of developing serious illness as a result of COVID-19 was one of the first reports used to reflect the health condition of infected people after hospital admission. The effects of COVID-19 are more severe in individuals with chronic noncommunicable diseases (NCDs), indicating that the characteristics and implic...

Lawsonia inermis Linn, commonly known as henna, is a member of the Lythraceae family and has been found to contain a variety of compounds with both industrial and medicinal applications in its stem, bark, roots, flowers, and seeds. This report provides a comprehensive review of the bioactive components, pharmacological activities, pharmacokinetics,...

Background Brazil is the destination of many international migrants and refugees and, given the circumstances of their entry into the country, many face difficulties due to the absence of targeted policies. Thus, the objective of this study was to survey the social impact of COVID-19 on international migrants and refugees regarding income loss, foo...

Introduction The objective of this systematic review is to identify tuberculosis (TB) high-risk among the general population globally. The review was conducted using the following steps: elaboration of the research question, search for relevant publications, selection of studies found, data extraction, analysis, and evidence synthesis. Methods The...

The SARS-CoV-2-triggered Public Health Emergency of International Importance has significantly contributed to emotional and mental health issues. The aim of this study was to identify factors associated with self-perceived mental health changes while facing the COVID-19 pandemic in Brazil. This was a cross-sectional, descriptive, and analytical stu...

Introduction: Drug-resistant tuberculosis (DR-TB) is a global threat and a challenge for public health authorities worldwide. In children, the diagnosis is even more challenging and DR-TB is poorly described in the literature, as are its treatment outcomes. In this study, we aimed to describe the treatment of drug-resistant TB in children and youn...

Background: Tuberculosis (TB) is a disease that is influenced by social determinants of health. However, the specific structural and intermediary determinants of TB in Eastern Amazonia remain unclear. Despite being rich in natural resources, the region faces significant challenges related to poverty, inequality, and neglected diseases. The objecti...

INTRODUCTION The objective of this systematic review is to identify tuberculosis hotspots among the general population globally. The review was conducted using the following steps: elaboration of the research question, search for relevant publications, selection of studies found, data extraction, analysis, and evidence synthesis. METHODS The guidi...

Morus alba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the M...

Morus alba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the M...

Lavandula species is a flowering plant that is common in Europe and across the Mediterranean. Lavender has many health benefits for humans. In addition to its use in herbal medicine, it is widely used in the fields of cosmetics, perfumes, foods, and aromatherapy. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant ma...

Paclitaxel (Taxol) is a potent natural anticancer drug that has evolved over the years. It has been useful in the management of many cancers. Hence, this review aims to appraise the pros and cons of paclitaxel in the management of cancers using literature. Paclitaxel acts by obstructing mitotic spindle formation attributed to clampdown of mitotic c...

Tuberculosis (TB) in children presents specificities in its diagnosis, which makes it prone to underreporting: therefore, the disease in this group is still a serious public health problem in several countries. We aimed to analyze the spatial distribution and temporal trend of childhood TB in Brazil. An ecological study with time series, spatial an...

Malva sylvestris is a plant commonly found in Europe, Asia, and Africa. The leaves and flowers of this plant have been used for centuries in traditional medicine to treat various ailments such as cough, cold, diarrhoea, and constipation. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemica...

Medicinal plants have a long track record of use in history, and one of them is Commiphora myrrh which is commonly found in the southern part of Arabia, the northeastern part of Africa, in Somalia, and Kenya. Relevant literatures were accessed via Google Scholar, PubMed, Scopus, and Web of Science to give updated information on the phytochemical co...

The roles of plants and its products in all forms of life cannot be overemphasized. The medicinal products from plant are phytochemicals, drugs, food supplements, beauty products, etc. In ethnomedicine, leaves, fruits, stem, bark, root and fluids from plants are used in the cure, management and prevention of several diseases. Cupressus sempervirens...

Objective: to assess the level of trust in health services during the COVID-19 pandemic in Brazil. Methods: A cross-sectional study, carried out between 2020 and 2021, among Brazilians over 18. Nonprobabilistic sampling was used. Descriptive and inferential statistics were applied, using the local bivariate Moran's technique to verify the existe...

(1) Background: Tuberculosis remains a public health problem in the world. The study analyzed the factors associated with drug-resistant tuberculosis in the prison population of the state of Paraná. (2) Methods: Ecological study of drug-resistant tuberculosis cases registered in the Paraná Information System, Brazil (2008 to 2018). We performed des...

Background: TB is a disease affected by social determinants of health; however, it is unclear what its structural and intermediary determinants are in Eastern Amazonia. The region contains many natural resources, yet it suffers drastically from poverty, inequality, and neglected diseases. Here, we aimed to employ mathematical modeling to evaluate t...

Objective: to assess level of trust in health services during COVID-19 pandemic in Brazil. Methods: Cross-sectional study, carried out between 2020 and 2021, among Brazilians over 18. A non-probabilistic sampling was used. Descriptive and inferential statistics were applied, using the Local Bivariate Moran’s technique was used to verify the existen...

Tamoxifen, a non-steroidal selective estrogen receptor modulator is a widely used drug for the prevention and breast cancer treatment. It binds to the hormone-receptors toprevent the binding of the cancer cells in the breast to the hormones they need for growth. It undergoes metabolic activation which converts it to an active metabolite (endoxifen...

Abstract. – OBJECTIVE: With the recent direction in drug repurposing, many approved drugs have been evaluated to assess their effect on the coronavirus or SARS-CoV-2 infection (COVID-19). Driving this path, chloroquine (CQ) has been used in the treatment of malaria and hydroxychloroquine (HCQ) in immunomodulatory and anti-thrombotic action, playing...

Background Tuberculosis remains a serious public health issue worldwide, affecting people in vulnerable situations. The study aimed to analyze factors associated with drug resistant tuberculosis among patients who were in prison in the state of Paraná. Method An ecological study was carried out on Drug-Resistant tuberculosis cases registered throug...

Objective: Cancer remains the major cause of death globally apart from cardiovascular diseases. Behavioural and dietary risks could trigger up to 70% of new cancer cases in the next 20 years based on speculations. The risk of cancer is becoming more rampant mainly because of various environmental carcinogens which are responsible for their initiati...

OBJECTIVE: The outbreak of the coronavirus disease 2019 (COVID-19), has thrown the world into panic as the pandemic continues to spread. The World Health Organization has maintained a close partnership with the governments of the world to design a global strategy against the spread of the disease. PATIENTS AND METHODS: This study aims to assess th...

OBJECTIVE: Since the outbreak of the novel coronavirus (COVID-19) in December, 2019 there has been a rapid spike in the burden of COVID-19 in North and South America, many physical, psychological, social, health and financial human endeavours have been affected. Hence, this review aims at assessing the knowledge and adherence of Americans to the pu...

Abstract Diabetes mellitus is a metabolic disorder that has become a global health problem. About 500 million people were estimated to be living with diabetes in 2018 with about 20 million in Africa and 2 million cases in Nigeria. Bioactive compounds offer an advanced starting point in the search for highly specific and potent modulator of bimolecu...