Timo Mappes

Timo Mappes
Friedrich Schiller University Jena | FSU · Deutsches Optisches Museum (D.O.M.)

Prof. Dr.-Ing. || Founding Director Deutsches Optisches Museum (D.O.M.)

About

119
Publications
18,715
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1,879
Citations
Introduction
Timo Mappes graduated in 2003 & received his PhD (Dr.-Ing.) with great distinction in 2006 at Karlsruhe Institute of Technology (KIT). In 2007 he received a grant for an independent junior research group @ KIT. He was visting professor at Technical University of Denmark in 2010. In 2012 he joined Carl Zeiss AG, 2015-2018 he was heading global R&D (Technology & Innovation) and Information Technology (IT) with procuration and about 200 FTE on four continents for ZEISS Vision Care. Here he was responsible for the development of the IP portfolio and for developing new and novel lens designs & production. In July 2018 Timo was appionted full professor and founding director of the German Optical Museum (D.O.M.) to create an internationally recognized research site and interactive museum at Jena.
Additional affiliations
July 2018 - present
Deutsches Optisches Museum (D.O.M.)
Position
  • Professor
Description
  • Designing Deutsches Optisches Museum (D.O.M.) basically from scratch. In parallel working as professor for the history of physics with a major in science communication at Friedrich-Schiller-Universität Jena.
August 2015 - June 2018
Carl Zeiss AG
Position
  • CEO
Description
  • Heading global Research & Development with procuration. Locations: Aalen (DE), Tübingen (DE), Guangzhou (CN), Lonsdale (AU), Mátészalka (HU), Tijuana (MX). About 170 + 30 FTE. Content: R&D of solutions for spectacles lenses: Optical design, development of (functional) optical coatings, development of new production concepts including aspects of industry 4.0, special purpose machinery manufacture, and R&D for disruptive production. Responsible for entire patent portfolio of ZEISS spectacles.
October 2012 - present
Karlsruhe Institute of Technology
Position
  • Microoptics and Lithography
Description
  • Privatdozent (private lecturer) Karlsruhe School of Optics and Photonics (KSOP)
Education
May 2003 - February 2006
Karlsruhe Institute of Technology
Field of study
  • Mechanical Engineering
October 1997 - March 2003
Karlsruhe Institute of Technology
Field of study
  • Mechanical Engineering

Publications

Publications (119)
Article
Full-text available
Microgoblet laser pairs are presented for cross-referenced on-chip biomolecular sensing. Parallel readout of the micro­lasers facilitates effective mutual filtering of highly localized refractive index and temperature fluctuations in the analyte. Cross-referenced detection of two different types of proteins and complete chemical transducer reconfig...
Article
Full-text available
Lasing from whispering-gallery mode (WGM) resonators occurs omnidirectional in azimuthal plane. Most applications of WGM resonators require spectral analysis with off-chip detectors, where in-plane emission and beam divergence hinder efficient detection. We demonstrate redirecting WGM laser emission from all azimuthal angles using a circular microm...
Article
Full-text available
Optically coupled microcavities have emerged as photonic structures with promising properties for investigation of fundamental science as well as for applications. We report on the fabrication and spatially resolved spectroscopy of on-chip photonic molecule (PM) lasers consisting of two coupled, dye-doped polymeric microdisks on a silicon substrate...
Article
Dawn of nanotechnology: The immersion ultramicroscope was patented a century ago. When an analyte was examined with an antique instrument and with state-of-the-art technology, the historic assumptions were confirmed: the size and shape of the nanoparticles are in the same range as that described 100 years ago. The spectra of the Tyndall cones cause...
Article
Full-text available
Laser light excitation of fluorescent markers offers highly sensitive and specific analysis for bio-medical or chemical analysis. To profit from these advantages for applications in the field or at the point-of-care, a plastic lab-on-a-chip with integrated organic semiconductor lasers is presented here. First order distributed feedback lasers based...
Article
Full-text available
The role of ultraviolet radiation in oxidative stress‐related ocular pathologies is less known than its role in skin cancer. Excessive exposure to ultraviolet radiation is associated with increased oxidative stress in eye tissues, which may promote the development of photokeratitis, cataract, and retinal damages. Children are especially vulnerable:...
Article
Full-text available
Ocular UV doses accumulate all-day, not only during periods of direct sun exposure. The UV protection efficiency of three clear lenses was evaluated experimentally, validated by simulation, and compared to non-UV protection: a first spectacle lens with a tailored UV absorber, a second spectacle lens, minimizing UV back reflections, as well as a thi...
Article
Full-text available
In the eye ultraviolet radiation (UVR) is not known to contribute to visual perception but to mainly damage multiple structures. UVR carries higher energy than visible light and high dose exposure to UVR causes direct cellular damage, which has an important role in the development of cancer. This review provides an overview on the most recent knowl...
Article
Full-text available
Whole-body optical imaging of post-embryonic stage model organisms is a challenging and long sought-after goal. It requires a combination of high-resolution performance and high-penetration depth. Optoacoustic (photoacoustic) mesoscopy holds great promise, as it penetrates deeper than optical and optoacoustic microscopy while providing high spatial...
Article
Scattering within biological samples limits the imaging depth and the resolution in microscopy. We present a prior and regularization approach for blind deconvolution algorithms to correct the influence of scattering to increase the imaging depth and resolution. The effect of the prior is demonstrated on a three-dimensional image stack of a zebrafi...
Conference Paper
Imaging depth is one of the most prominent limitations in light microscopy. The depth in which we are still able to resolve biological structures is limited by the scattering of light within the sample. We have developed an algorithm to compensate for the influence of scattering. The potential of algorithm is demonstrated on a 3D image stack of a z...
Article
Intravital imaging of large specimens is intrinsically challenging for postembryonic studies. Selective plane illumination microscopy (SPIM) has been introduced to volumetrically visualize organisms used in developmental biology and experimental genetics. Ideally suited for imaging transparent samples, SPIM can offer high frame rate imaging with op...
Cover Page
Full-text available
In article 1500066, U. Bog, M. Hirtz, and co‐workers demonstrate on‐chip biomolecular sensing using whispering‐gallery‐mode microgoblet lasers. Biomolecular detection is usually affected by signal disturbances, induced by refractive index and temperature fluctuations inside the liquid analyte. The densely packed laser pairs enable mutual and locali...
Article
Full-text available
We present an all-polymer photonic sensing platform based on whispering-gallery mode microgoblet lasers integrated into a microfluidic chip. The chip is entirely made from polymers, enabling the use of the devices as low-cost disposables. The microgoblet cavities feature quality factors exceeding 10(5) and are fabricated from poly(methyl methacryla...
Conference Paper
Full-text available
NEMO is the European "Network of Excellence on Micro-Optics". One of the objectives is to disseminate knowledge on micro-optics. Therefore NEMO plans to inform pupils about the crucial role of micro-optics This is done through the distribution of an educational kit to their physics/technology teachers. This kit has been realized through a cooperati...
Article
We present our latest results on microgoblet lasers as biosensors. Surface functionalization is performed with high resolution and throughput by aligned microcontact stamping. We show simultaneous device readout, the resulting cross-referencing capabilities and functionalization reconfiguration.
Conference Paper
We report on the fabrication of polymeric whispering-gallery mode (WGM) lasers. Our approach enables high packing density by vertical stacking and multiplexed readout of resonators and lends itself to signal referencing or multi-target sensing.
Chapter
We report on whispering gallery mode (WGM) resonators consisting of poly(methyl methacrylate) (PMMA) which are promising candidates for label-free biosensing applications. The optical modes in these resonators experience a wavelength shift when the refractive index of the surrounding medium changes or when molecules attach to the resonator. Differe...
Article
We report on whispering gallery mode (WGM) resonators consisting of poly(methyl methacrylate) (PMMA) which are promising candidates for labelfree biosensing applications. The optical modes in these resonators experience a wavelength shift when the refractive index of the surrounding medium changes or when molecules attach to the resonator. Differen...
Cover Page
Full-text available
A novel surface functionalization technique is presented for large-scale selective molecule deposition onto whispering gallery mode microgoblet cavities. The parallel technique allows damage-free individual functionalization of the cavities, arranged on-chip in densely packaged arrays. As the stamp pad a glass slide is utilized, bearing phospholipi...
Article
Full-text available
The integration of organic semiconductor distributed feedback (DFB) laser sources into all-polymer chips is promising for biomedical or chemical analysis. However, the fabrication of DFB corrugations is often expensive and time-consuming. Here, we apply the method of laser-assisted replication using a near-infrared diode laser beam to efficiently f...
Conference Paper
We demonstrate an organic semiconductor distributed feedback (DFB) laser as excitation source in surface-enhanced Raman spectroscopy (SERS). SERS-active substrates comprising nanopillar arrays were fabricated by the technique of laser-assisted nano-replication.
Conference Paper
We report on polymeric high-Q microresonators and a method for spatially selective functionalization. Furthermore we present coupled resonators exhibiting a higher bulk refractive index sensitivity than single resonators making them promising candidates for high-sensitivity sensing.
Patent
Full-text available
An opto-mechanical switch produces different optical paths from two optical path sections out of a plurality of optical path sections that are oriented in different spatial directions. The switch has an optical component on which one end of each optical path section impinges, and which is adapted to be moved linearly in a direction of movement at r...
Article
Full-text available
As an application of organic semiconductor distributed feedback (DFB) lasers we demonstrate their use as excitation sources in Raman spectroscopy. We employed an efficient small molecule blend, a high quality resonator and a novel encapsulation method resulting in an improved laser output power, a reduced laser line width and an enhanced power stab...
Article
Full-text available
Optically excited organic semiconductor distributed feedback (DFB) lasers enable efficient lasing in the visible spectrum. Here, we report on the rapid and parallel fabrication of DFB lasers via transferring a nanograting structure from a flexible mold onto an unstructured film of the organic gain material. This geometrically well-defined structure...
Conference Paper
The paper reports on lasing and sensing properties of poly(methyl methacrylate) (PMMA) microgoblet resonators doped with the laser dye Pyrromethene 597 (PM597). The evanescent field of the microgoblet lasers can be used for label-free detection of molecules attaching to the cavity's surface. Binding of a monolayer of molecules to the cavity's surfa...
Article
Full-text available
We report on a novel approach to realize on-chip microlasers, by applying highly localized and material-saving surface functionalization of passive photonic whispering gallery mode microresonators. We apply dip-pen nanolithography on a true three-dimensional structure. We coat solely the light-guiding circumference of pre-fabricated poly(methyl met...
Article
Full-text available
We report on the development of backplane modules with integrated microvalves and optical switches enabling custommade system design of analysis systems. The backplane modules are reversibly interconnected by magnetostatic connectors and provide optical and fluidic coupling to four neighboring backplane modules and one optical sensor module, which...
Article
We demonstrate the applicability of polymeric whispering gallery mode resonators fabricated on silicon as biosensors. Optical measurements on the passive resonators in the visible spectral range yield Q-factors as high as 1.3 x 10(7). Local, covalent surface functionalization, is achieved by spatially controlled UV-exposure of a derivative of the p...
Article
Full-text available
Optofluidics is increasingly gaining impact in a number of different fields of research, namely biology and medicine, environmental monitoring and green energy. However, the market for optofluidic products is still in the early development phase. In this manuscript, we discuss modular platforms as a potential concept to facilitate the transfer of o...
Patent
Full-text available
A microoptical component for coupling a laser light to microresonators includes at least two microresonators, each having a form of an axially symmetric body disposed on a pedestal, and at least one waveguide for the laser light. The at least two microresonators are disposed on a first substrate having first side walls. The at least one waveguide i...
Article
Beobachtung von Nanopartikeln: Das Patent des Immersions‐Ultramikroskops wurde vor hundert Jahren angemeldet. Die Untersuchung einer Probe mit einem historischen Instrument und der Vergleich mit modernen Methoden bestätigte die historischen Vermutungen: Größe und Form der Nanopartikel entsprechen der Beschreibung vor 100 Jahren, ebenso die Spektren...
Conference Paper
Meeting the need of biomedical users, we develop disposable Lab-on-a-Chip systems based on commercially available polymers. We are combining passive microfluidics with active optical elements on-chip by integrating multiple solid-state and liquid-core lasers. While covering a wide range of laser emission wavelengths, the chips have the size of micr...
Article
Full-text available
We report on a method for a highly flexible arrangement of polymeric high-Q whispering gallery mode resonators. Parallel on-chip fabricated goblet resonators are detached from the substrate by bonding a gold wire to the field-free center of their polymeric cavity. This enables the precise control of the resonator's spatial position. The modal spect...
Article
Full-text available
We report the fabrication of nanoporous liquid core lasers via direct laser writing based on two-photon absorption in combination with thiolene-chemistry. As gain medium Rhodamine 6G was embedded in the nanoporous polybutadiene matrix. The lasing devices with thresholds of 19 µJ/mm<sup>2</sup> were measured to have bulk refractive index sensitiviti...
Article
Full-text available
Lab-on-a-chip systems made of polymers are promising for the integration of active optical elements, enabling e.g. on-chip excitation of fluorescent markers or spectroscopy. In this work we present diffusion operation of tunable optofluidic dye lasers in a polymer foil. We demonstrate that these first order distributed feedback lasers can be operat...
Article
Full-text available
Ink-jet-printed organic distributed feedback (DFB) lasers are realized by employing light-emitting copolymer and suitable organic solvents to meet the demands of printability and optical amplification in a nanopatterned conjugated polymer slab waveguide. We demonstrate the accurate lateral positioning of ink-jet-printed patches of the gain material...
Article
Full-text available
Sensors based on surface plasmon resonances (SPRs) have proven themselves as promising devices for molecular investigations - still there is potential to determine the geometrical parameter set for optimal sensing performance. Here we propose a comprehensive design rule for one-dimensional plasmonic grating structures. We present an analytical appr...
Conference Paper
In recent years, microfluidic devices have become important tools for cell analysis in biology and medicine. They enable fast and inexpensive analysis with reduced consumption of analytes. However, for optical detection involving FACS (fluorescence-activated cell sorting), sample preparation by attaching an antibody-labeled fluorochrome to the cell...
Conference Paper
Whispering-gallery mode (WGM) resonators are known to offer outstanding properties for applications in photonics and telecommunication. Despite their promising performance, one major obstacle for the use of WGM resonators in industrial products is the need of expensive components and high-precision setups for their operation, requiring a controlled...
Article
Full-text available
The fabrication and characterization of continuously tunable, solution-processed distributed feedback (DFB) lasers in the visible regime is reported. Continuous thin film thickness gradients were achieved by means of horizontal dipping of several conjugated polymer and blended small molecule solutions on cm-scale surface gratings of different perio...
Conference Paper
Most Lab-on-a-Chip systems require a platform with external supply and control units to be operated. In this manuscript, we report on the development of a modular optoelectronic microfluidic backplane, enabling the flexible interconnection, supply, and control of microfluidic and optofluidic devices. The developed system was fabricated in polymers...
Conference Paper
We develop optical Lab-on-a-Chips on different platforms for marker-based and label-free biophotonic sensor applications. Our chips are based on polymers and fabricated by mass production technologies to integrate microfluidic channels, optical waveguides and miniaturized lasers.
Article
Taking a closer look at nature reveals fascinating insights into the architectural complexity of multifunctional surfaces of living organisms. The scaling of their surface topographies often covers multiple orders of magnitude, and the topographical features are typically found on non-planar, curved surfaces. Prominent examples for such complex sur...
Conference Paper
Full-text available
Lab-on-a-Chip (LoC) systems enable biomedical or chemical testing for point-of-care analysis at the patient's bedside or in the field. Our work is focused on developing optical LoCs based on polymers by integrating microfluidic channels, optical waveguides, and miniaturized lasers on different platforms. The chips introduced in our work are using o...
Conference Paper
Full-text available
We report the integration of an electrically pumped GaAs-based oxide-confined vertical-extended-cavity surface-emitting laser and a microfluidic chip. Particles in the microchannels flow through the laser resonator and induce a change of the cavity resonance, thus allowing sensitive detection to trigger a subsequent sorting process.
Article
Full-text available
Voltage-controlled continuous tuning of the laser wavelength of an organic distributed feedback laser is demonstrated by incorporation of liquid crystals (LCs) in the top cladding layer. Orientation of the LCs and hence the modal refractive index are controlled by applying a lateral electrical field. Laser emission shifts by 4 nm at an applied volt...
Chapter
Full-text available
Ein Großteil der Studierenden plant seine Lernaktivitäten ausgehend von den Prüfungsanforderungen für das jeweilige Fach. Diese Erkenntnis sollten Lehrende sich nach John Biggs (Professor für Psychologie an der Universität Hong-Kong) zu Nutze machen: Constructive Alignment ist ein Prinzip der Hochschuldidaktik, das genutzt wird, um die Lernziele, d...
Article
Full-text available
We report the fabrication of high-Q polymeric microdisks on silicon via direct laser writing utilizing two-photon absorption induced polymerization. The quality factors of the passive cavities are above 10(6) in the 1300 nm wavelength region. The flexible three-dimensional (3D) lithography method allows for the fabrication of different cavity thick...
Article
We present a parallel production process enabling the integration of multiple organic semiconductor laser light sources into a PMMA chip intended for the excitation of fluorescent markers of biological samples.
Article
We present poly(methyl methacrylate) (PMMA) based microfluidic systems for biophotonic sensing applications. The fabrication of the devices is based on thermal nanoimprinting and thermal bonding of polymer substrates. We integrate and encapsulate distributed feedback (DFB) organic semiconductor lasers based on tris(8-hydroxyquinoline) aluminium (Al...
Article
Full-text available
We investigate lasing from high-Q, polymeric goblet-type microcavities covered by an organic semiconductor gain layer. We analyze the optical modes in the high-Q cavities using finite element simulations and present a numerical method to determine the cutoff thickness of the gain layer above which the whispering gallery modes are strongly confined...
Article
We report laser action from conical polymeric microcavities. A thin film of the organic semiconductor tris(8-hydroxyquinoline) aluminum (Alq<sub>3</sub>) doped with the laser dye 4-dicyanmethylene-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran (DCM) on top of the microcones enables low-threshold lasing when pumped with a conventional blu-ray laser dio...
Article
We report on a new type of high-Q microresonator made of poly(methyl methacrylate) (PMMA) with a conical shape. First results on biosensing with proteins are presented. ©2010 Optical Society of America OCIS codes: 280.1415, 160.4760, 160.5470, 220.4000