Tim Kendall

Tim Kendall
Royal College of Psychiatrists · National Collaborating Centre for Mental Health

About

72
Publications
26,302
Reads
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5,367
Citations
Citations since 2016
13 Research Items
3126 Citations
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20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
Introduction
Skills and Expertise

Publications

Publications (72)
Article
Full-text available
Background Over 600 RCTs have demonstrated the effectiveness of psychosocial interventions for children and young people’s mental health, but little is known about the long-term outcomes. This systematic review sought to establish whether the effects of selective and indicated interventions were sustained at 12 months. Method We conducted a system...
Article
Full-text available
Background Self-management is intended to empower individuals in their recovery by providing the skills and confidence they need to take active steps in recognising and managing their own health problems. Evidence supports such interventions in a range of long-term physical health conditions, but a recent systematic synthesis is not available for p...
Article
Background: Cognitive-behavioral therapy (CBT) is first choice of treatment for depressive symptoms and disorders in adolescents, however improvements are necessary because overall efficacy is low. Insights on CBT components and contextual and structural characteristics might increase the efficacy. The aim of our approach is to evaluate the effica...
Data
Supplementary_Material – Supplemental material for Specialized psychotherapies for adults with borderline personality disorder: A systematic review and meta-analysis
Article
Full-text available
Objective: Borderline personality disorder affects up to 2% of the population and is associated with poor functioning, low quality of life and increased mortality. Psychotherapy is the treatment of choice, but it is unclear whether specialized psychotherapies (dialectical behavior therapy, mentalization-based treatment, transference-focused therap...
Article
Background Bulimia nervosa (BN) is a severe eating disorder that can be managed using a variety of treatments including pharmacological, psychological, and combination treatments. We aimed to compare their effectiveness and to identify the most effective for the treatment of BN in adults. Methods A search was conducted in Embase, Medline, PsycINFO...
Article
A recent editorial claimed that the 2014 National Institute for Health and Care Excellence (NICE) guideline on psychosis and schizophrenia, unlike its equivalent 2013 Scottish Intercollegiate Guidelines Network (SIGN) guideline, is biased towards psychosocial treatments and against drug treatments. In this paper we underline that the NICE and SIGN...
Article
Tourette syndrome (TS) and chronic tic disorder (CTD) affect 1–2% of children and young people, but the most effective treatment is unclear. To establish the current evidence base, we conducted a systematic review of interventions for children and young people. Methods: Databases were searched from inception to 1 October 2014 for placebo-controll...
Article
Full-text available
Psychological interventions may be beneficial for bipolar disorder. Aims Efficacy evaluation of psychological interventions for adults with bipolar disorder. Methods A systematic review of randomised controlled trials.. Outcomes were meta-analysed using RevMan and confidence assessed using the GRADE-method. Results We included 55 trials with 6010 p...
Article
Full-text available
Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment. Objective To conduct a systematic review of the benefits and risks of pharmacological, behavioural and physical in...
Article
Full-text available
Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment. Objective: To conduct a systematic review of the benefits and risks of pharmacological, behavioural and physical in...
Article
Full-text available
Tourette syndrome (TS) among young people is associated with psychosocial difficulties and parents play an important role in the management of the condition. Clinical guidelines have been developed for the treatment of TS and tics, but little is known about how young people and their parents perceive their treatment options or their desired outcome...
Article
Full-text available
Background Informal caregiving is an integral part of the care of people with severe mental illness, but the support needs of those providing such care are not often met. Aims To determine whether interventions provided to people caring for those with severe mental illness improve the experience of caring and reduce caregiver burden. Method We cond...
Article
Full-text available
Studies report contrasting results regarding the efficacy and safety of pharmacological, psychological, and combined interventions in psychosis and schizophrenia in children, adolescents and young adults. Systematic review and meta-analysis. Embase, Medline, PreMedline, PsycINFO, and CENTRAL were searched to July 2013 without restriction to publica...
Article
One quarter of children and young people (CYP) experience anxiety and/or depression before adulthood, but treatment is sometimes unavailable or inadequate. Self-help interventions may have a role in augmenting treatment and this work aimed to systematically review the evidence for computerised anxiety and depression interventions in CYP aged 5-25 y...
Article
Full-text available
The widespread availability of the Internet and mobile-device applications (apps) is changing the treatment of mental health problems. The aim of the present study was to review the research on the effectiveness of e-therapy for eating disorders, using the methodology employed by the UK’s National Institute for Health and Care Excellence (NICE). El...
Article
Full-text available
Bipolar disorder is a complex, recurrent, and severe mental illness that has an onset typically between 13 and 30 years of age and a lifetime prevalence of 1.4%.1 It is characterised by episodes of mania or hypomania with elation, overactivity, and disinhibited behaviour, as well as episodes of depression with profound loss of interest and motivati...
Article
Full-text available
Little is known about whether peer support improves outcomes for people with severe mental illness. A systematic review and meta-analysis was conducted. Cochrane CENTRAL Register, Medline, Embase, PsycINFO, and CINAHL were searched to July 2013 without restriction by publication status. Randomised trials of non-residential peer support intervention...
Article
Psychosis is relatively common, with schizophrenia being the most prevalent form of psychotic disorder, affecting about seven in 1000 adults, with onset typically occurring between the ages of 15 and 35.1 These disorders, which are characterised by distressing hallucinations and delusions, disturbed behaviour, and memory and motivation problems, pr...
Article
This approach can work Poor adherence to treatment is a problem across the whole of medicine, with people not attending appointments, not taking their drugs as prescribed, or not taking them at all. More than 50% of people with schizophrenia have been estimated not to adhere to prescribed drugs,1 leading to higher rates of relapse and hospital ad...
Article
Autism occurs in approximately 1% of children and young people,1 though the diagnosis is made less commonly in girls2 and anyone with severe intellectual disability.1 It is one of the most important causes of lifelong disability, with support and lost productivity costs estimated at more than £28bn (€32bn, $43bn) annually in the UK.3 Individual pre...
Article
Background Generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders, with important implications for patients and healthcare resources. However, few economic evaluations of pharmacological treatments for GAD have been published to date, and those available have assessed only a limited number of drugs. Objective To assess th...
Article
Psychosis, including schizophrenia, comprises a major group of psychiatric disorders characterised by hallucinations and/or delusions (psychotic symptoms) that alter perception, thoughts, affect, and behaviour, and which can considerably impair a child or young person’s development, relationships, and physical health. Schizophrenia is estimated to...
Article
Full-text available
Objective To determine whether any psychological, pharmacological, or nutritional interventions can prevent or delay transition to psychotic disorders for people at high risk. Design Systematic review and meta-analysis. Data sources Embase, Medline, PreMedline, PsycINFO, and CENTRAL were searched to November 2011 without restriction to publication...
Data
Full-text available
Web appendices: Supplementary material
Article
Ellis and Yates highlight the recommendations on risk scales.1 2 3 A central question is whether healthcare professionals should be able to accurately predict adverse outcomes after self harm. The literature review carried out for the guideline suggests that this is not a realistic aim.4 After a first self harm episode, most people will not repeat...
Article
Full-text available
Two recent meta-analyses claim that abortion leads to a deterioration in mental health. Previous reviews concluded that the mental health outcomes following an unwanted pregnancy are much the same whether the woman gives birth or terminates the pregnancy, although there is an increased mental health risk with an unwanted pregnancy. Meta-analysis is...
Article
The antipsychotics brought hope and optimism to people with schizophrenia and to those who care for them. There have been successive classes of antipsychotics used by the pharmaceutical industry to persuade doctors and patients that 'new' is better. Evidence is growing that the primary purpose of these fabricated classes is for marketing. It is tim...
Article
The guideline programme developed by the National Collaborating Centre for Mental Health (NCCMH) for the National Institute for Health and Clinical Excellence (NICE) is probably the most comprehensive and methodologically advanced mental health guideline programme in the world, covering most adults and children with mental health problems and addre...
Article
Many people with mental health problems use substances (including illicit drugs and alcohol), and for people with psychosis (predominantly schizophrenia and bipolar disorder), substance misuse occurs more frequently than in the general population.1 2 For example, a 1990 study in the United States reported a 47% lifetime prevalence rate of substance...
Article
The National Collaborating Centre for Mental Health and the National Institute for Health and Clinical Excellence point out that one of the recommendations in the summary …
Article
Cost-effectiveness analysis often requires information on the effectiveness of interventions on multiple outcomes, and commonly these take the form of competing risks. Nevertheless, methods for synthesis of randomized controlled trials with competing risk outcomes are limited. The aim of this study was to develop and illustrate flexible evidence sy...
Article
Early intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments. To evaluate the effectiveness of early intervention services, cognitive-behavioural therapy (CBT) and family intervention in early psychosis. Systematic review and meta-analysis of random...
Article
Background: The NICE ADHD Guideline Group found a lack of research evidence on young people’s experiences with stimulant medications. The present study was commissioned to help fill this gap in the evidence base and to inform the Guideline. Method: Focus groups and 1:1 interviews with 16 UK young people with ADHD. Results: Young people were positiv...
Chapter
This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the clinical effects and safety of antipsychotic drugs in comparison with placebo or another antipsychotic drug in the treatment of people with persistent negative symptoms of schizophrenia and schizophrenia-like psychosis.
Article
In their review of drug treatments for borderline personality disorder, Lieb et al ,[1][1] despite considering similar evidence, draw largely different conclusions from those we drew when developing the National Institute for Health and Clinical Excellence (NICE) guideline.[2][2] Lieb et al
Article
This second in a two-part unit on updated NICE guidance on schizophrenia looks at treating acute episodes and promoting recovery. Part 1 examined detection, assessment and starting treatment.
Article
Decisions about drugs by doctors, patients, and the public depend on a complex framework of industry regulation, professional and public guidance, and transparent publication of the research on which the regulatory framework depends. In the UK, there are two agencies with a national role in this decision-making process. First, a regulator, the Medi...
Article
Why read this summary?Personality disorders are common, with an estimated prevalence in the community of 4.4%.1 They can significantly impair personal and social functioning, with considerable cost to health services, society, the criminal justice system, and the individual. Of the 10 classified types of personality disorder, borderline and antisoc...
Article
This is a two-part unit on therapeutic interventions in dementia, based on NICE and SCIE (2006) guidance. Part 1 outlined management strategies for cognitive symptoms and how to maintain function. This second part examines interventions for non-cognitive symptoms.
Article
The first in this two-part unit on therapeutic interventions in dementia outlines how to maintain function and independence for patients with dementia. It also examines specific interventions for cognitive symptoms.
Article
In response to the article by Wood et al 1 on the current state of knowledge among doctors on acute gut decontamination, we would point out that the National Institute for Health and Clinical Excellence (NICE) self-harm guideline published in 2004 addresses this issue in its guidance about the general management of patients who have self-poisoned.2...
Article
Full-text available
Aims and Method To investigate implementation of National Institute for Health and Clinical Excellence (NICE) guidelines in mental health, focusing on the schizophrenia guideline. Data analyses centred on implementation of the guideline, as well as looking at a set of markers mapped to the NICE principles of implementation and other identified clin...
Article
The aim is to summarize recent evidence from the National Institute for Health and Clinical Excellence clinical guidelines and high-quality systematic reviews for the use of cognitive behavioural therapy to treat children and adolescents with mental health problems. Data from meta-analyses of randomized controlled trials suggest that the best evide...
Article
Full-text available
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood condition that may affect different areas of the child’s life, seriously impairing academic achievement, peer relationships, and self care. Many affected children become socially isolated and develop conduct problems. Some 15% of children with ADHD will still have the condition i...
Article
Full-text available
Internationally, interest is developing in the challenges of developing evidence-based guidelines for social work practice. The paper reports on the process of establishing the UK’s first joint health and social care evidence-based practice guideline, which is in dementia care. The paper addresses the methodological and procedural challenges of rev...
Article
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The selective publication of clinical trials by the pharmaceutical industry and by academic investigators has long been a contentious area in medicine. Clinicians and scientists such as Iain Chalmers, one of the founders of the UK Cochrane Centre, have worked for over two decades to address the problem of the under-reporting of research, suggesting...
Article
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Previous research suggests that social workers experience high levels of stress and burnout but most remain committed to their work. To examine the prevalence of stress and burnout, and job satisfaction among mental health social workers (MHSWs) and the factors responsible for this. A postal survey incorporating the General Health Questionnaire, Ma...
Article
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Two-thirds of councils with social services responsibilities (CSSRs) took part in a UK survey of mental health social workers. A one in five sample of front line workers was drawn, and 237 respondents completed a questionnaire and diary about their work context and content, and their attitudes to their work, their employer, mental health policy and...
Article
Full-text available
In the UK, applications for involuntary admission to psychiatric units are made mainly by specially trained approved social workers (ASWs). Proposed changes in the legislation will permit other professionals to undertake these statutory duties. This study aimed to examine how ASW status impacts upon work pattern and workload stresses by comparing A...
Article
This article summarizes recent developments in the use of selective serotonin reuptake inhibitors and atypical antidepressants to treat children and adolescents with depression at a time when their use in this context has generated considerable controversy and confusion for clinicians, patients and their families. Recent reports and recommendations...
Article
Questions concerning the safety of selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression in children led us to compare and contrast published and unpublished data on the risks and benefits of these drugs. We did a meta-analysis of data from randomised controlled trials that evaluated an SSRI versus placebo in participants a...

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