Tiffanie Maree Nelson

Tiffanie Maree Nelson
The University of Newcastle, Australia

PhD, BSc(MarBio)(Hons), Dip.App.Sci.(Bio.Tech.)

About

49
Publications
10,037
Reads
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863
Citations
Additional affiliations
October 2014 - January 2016
Montana State University
Position
  • PostDoc Position
April 2012 - March 2014
Australian Institute of Marine Science
Position
  • PostDoc Position
October 2007 - April 2011
UNSW Sydney
Position
  • PhD Student

Publications

Publications (49)
Article
The soil surface of drylands can typically be colonized by cyanobacteria and other microbes, forming biological soil crusts or ‘biocrusts’. Biocrusts provide critical benefits to ecosystems and are a common component of the largely arid and semi‐arid Australian continent. Yet, their distribution and the parameters that shape their microbial composi...
Article
Full-text available
Microbialites are sedimentary rocks created in association with benthic microorganisms. While they harbour complex microbial communities, Cyanobacteria perform critical roles in sediment stabilisation and accretion. Microbialites have been described from permanent and ephemeral saline lakes in South Australia; however, the microbial communities tha...
Article
Full-text available
Objective Despite the move to at-home, small-volume collection kits to facilitate large population-based studies of faecal microbial compositional profiling, there remains limited reporting on potential impacts of faecal subsampling approaches on compositional profiles. This study aimed to compare the microbial composition from faecal subsamples (<...
Article
Bacterial vaginosis (BV) is the most common vaginal disorder of reproductive-aged women, yet its etiology remains enigmatic. One clinical symptom of BV, malodor, is linked to the microbial production of biogenic amines (BA). Using targeted liquid chromatography mass-spectrometry, we analyzed 149 longitudinally collected vaginal samples to determine...
Article
Full-text available
Background The analysis of blow microbiota has been proposed as a biomarker for respiratory health analysis in cetaceans. Yet, we lack crucial knowledge on the long-term stability of the blow microbiota and its potential changes during disease. Research in humans and mice have provided evidence that respiratory disease is accompanied by a shift in...
Article
Full-text available
(1) Background: Individuals with diabetes and chronic kidney disease display gut dysbiosis when compared to healthy controls. However, it is unknown whether there is a change in dysbiosis across the stages of diabetic chronic kidney disease. We investigated a cross-sectional study of patients with early and late diabetes associated chronic kidney d...
Article
Full-text available
A wines’ terroir, represented as wine traits with regional distinctiveness, is a reflection of both the biophysical and human-driven conditions in which the grapes were grown and wine made. Soil is an important factor contributing to the uniqueness of a wine produced by vines grown in specific conditions. Recent data shows that the composition, div...
Preprint
Full-text available
Invasive species cause negative environmental and economic impacts worldwide. Their management may be improved by clarifying the role of behavior in advancing invasions. Gut microbial communities are known to affect behavior of wild populations, but their impact on behavior underlying invasiveness remains unexplored. Invasive populations of the can...
Preprint
Full-text available
Soil is an important factor that contributes to the uniqueness of a wine produced by vines grown in specific conditions. Recent data shows that the composition, diversity and function of soil microbial communities may play important roles in determining wine quality and indirectly affect its economic value. Here, we evaluated the impact of environm...
Article
Full-text available
Humpback whales endure several months of fasting while undertaking one of the longest annual migrations of any mammal, which depletes the whales’ energy stores and likely compromises their physiological state. Airway microbiota are linked to respiratory health in mammals. To illuminate the dynamics of airway microbiota in a physiologically challeng...
Article
Western boundary currents (WBCs) redistribute heat and oligotrophic seawater from the tropics to temperate latitudes, with several displaying substantial climate change‐driven intensification over the last century. Strengthening WBCs have been implicated in the poleward range expansion of marine macroflora and fauna, however, the impacts on the str...
Article
e15152 Background: The gut microbiome has been shown to modify the efficacy of cancer immunotherapy. Currently, there is little understanding of how the microbiome in advanced cancer patients responding to immunotherapy compares to healthy individuals. The aim of this study was to characterise the intestinal microbiome in patients with advanced sol...
Article
Full-text available
Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans. It is the third most common human mycobacterial disease after tuberculosis (TB) and leprosy. The available methods for detection of the bacilli in lesions are microscopic detection, isolation and cultivation of the bacterium, histopathology, and pol...
Preprint
Full-text available
Background: The analysis of blow microbiota has been proposed as a biomarker for respiratory health analysis in cetaceans. Yet, we lack crucial knowledge on the long-term stability of the blow microbiota and its potential changes during disease. Research in humans and mice have provided evidence that respiratory disease is accompanied by a shift in...
Preprint
Background: Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans (M. ulcerans disease). It is the third most common human mycobacterial disease after tuberculosis (TB) and leprosy. The available methods for detection of the bacilli in ulcers are microscopic detection, isolation and cultivation of the b...
Article
The number of social contacts of mammals is positively correlated with the diversity of their gut microbes. There is some evidence that sociality also affects microbes in the respiratory tract. We tested whether the airway microbiota of cetacean species differ depending on the whales’ level of sociality. We sampled the blow of blue (Balaenoptera mu...
Preprint
Background: Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans (M. ulcerans disease). It is the third most common human mycobacterial disease after tuberculosis (TB) and leprosy. The available methods for detection of the bacilli in ulcers are microscopic detection, isolation and cultivation of the b...
Article
Full-text available
Non‐invasive sampling methods for studying intestinal microbiome are widely applied in studies of endangered species and in those conducting temporal monitoring during manipulative experiments. Although existing studies show that non‐invasive sampling methods among different taxa vary in their accuracy, to date, no studies have been published compa...
Article
Full-text available
Objective: Characterise the vaginal metabolome of cervical HPV-infected and uninfected women. Design: Cross-sectional. Setting: The Center for Health Behavior Research at the University of Maryland School of Public Health. Sample: Thirty-nine participants, 13 categorised as HPV-negative and 26 as HPV-positive (any genotype; HPV+ ), 14 of who...
Preprint
Background: Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans (M. ulcerans disease). It is the third most common human mycobacterial disease after tuberculosis (TB) and leprosy. The available methods for detection of the bacilli in ulcers are microscopic detection, isolation and cultivation of the b...
Article
An emerging novel therapeutic agent for major depressive disorder, minocycline, has the potential to influence both gut microbiome and inflammatory status. The present study showed that chronic high fat diet feeding led to changes in both behaviour and the gut microbiome in male mice, without an overt inflammatory response. The diet-induced behavio...
Article
Full-text available
Cetacean represent vulnerable species impacted by multiple stressors, including reduction in prey species, habitat destruction, whaling and infectious disease. The composition of blow microbiota has been claimed to provide a promising tool for non-invasive health monitoring aiming to inform conservation management. Still, little is known about the...
Article
Full-text available
We present an optimised metagenomics method for detection and characterisation of all virus types including single and double stranded DNA/RNA and enveloped and non-enveloped viruses. Initial evaluation included both spiked and non-spiked bird faecal samples as well as non-spiked human faecal samples. From the non-spiked bird samples (Australian Mu...
Article
Full-text available
We evaluated the presence of coronaviruses by PCR in 918 Australian wild bird samples collected during 2016-17. Coronaviruses were detected in 141 samples (15.3%) from species of ducks, shorebirds and herons and from multiple sampling locations. Sequencing of selected positive samples found mainly gammacoronaviruses, but also some deltacoronaviruse...
Article
Full-text available
Cigarette smoking has been associated with both the diagnosis of bacterial vaginosis (BV) and a vaginal microbiota lacking protective Lactobacillus spp. As the mechanism linking smoking with vaginal microbiota and BV is unclear, we sought to compare the vaginal metabolomes of smokers and non-smokers (17 smokers/19 non-smokers). Metabolomic profiles...
Article
Forecasted climate-change models predict that much of northern Australia's coastal habitats will be in retreat because of saltwater intrusion (SWI) from sea-level rise. A region of primary concern is the nutrient-rich and biodiverse floodplains of world heritage-listed Kakadu National Park (KNP). To understand the implications of SWI, we need funda...
Conference Paper
Introduction Recent studies have reported associations between bacterial vaginosis (BV) and cervicovaginal HPV. To obtain further insight into this relationship, we examined the vaginal microbiota and metabolome of women who were HPV+ and HPV-. Methods Thirty-nine women self-collected mid-vaginal swabs that were profiled for bacterial composition...
Article
Full-text available
We present the near complete virus genome sequences with phylogenetic and network analyses of potential transmission networks of a total of 18 Australian cases of human parechovirus type 3 (HPeV3) infection in infants in the period from 2012–2015. Overall the results support our previous finding that the Australian outbreak strain/lineage is a resu...
Article
Full-text available
Human parechovirus types 1–16 (HPeV1–16) are positive strand RNA viruses in the family Picornaviridae. We investigated a 2015 outbreak of HPeV3 causing illness in infants in Victoria, Australia. Virus genome was extracted from clinical material and isolates and sequenced using a combination of next generation and Sanger sequencing. The HPeV3 outbre...
Article
Bacterial communities in floodplain and wetland soils cycle elements essential for flora and fauna. The coastal habitats of northern Australia are threatened with increasing saltwater intrusion (SWI) events that will destroy freshwater habitats. The effect of the impending SWI on bacterial communities is unknown. Here, we examined the bacterial com...
Article
Full-text available
Bacterial vaginosis (BV) is the most common vaginal disorder among reproductive age women. One clinical indicator of BV is a "fishy" odor. This odor has been associated with increases in several biogenic amines (BAs) that may serve as important biomarkers. Within the vagina, BA production has been linked to various vaginal taxa, yet their genetic c...
Conference Paper
Introduction Cigarette smoking is strongly associated with bacterial vaginosis (BV) and a low-Lactobacillus vaginal community state type (CST). Metabolite profiles have previously been shown to delineate BV and non-BV women and appear to be influenced by microbial composition. Therefore, we sought to determine if vaginal metabolites varied between...
Article
Full-text available
Marine mammals are globally significant because of their sensitivity to environmental change and threatened status, often serving as ‘ecosystem sentinels’. Disease is a major cause of marine mammal population decline and the role of the microbiome in disease has generated considerable interest. Recent research in humans has greatly enhanced our und...
Article
Saltwater intrusion (SWI) can result in the loss of dominant vegetation from freshwater habitats. In northern Australia, sea level is predicted to rise 17–50 cm by 2030–2070. This will exacerbate the impact of SWI, threatening Ramsar-listed habitats. Soil bacteria in these habitats play a significant role in biogeochemical cycling, regulating avail...
Article
Full-text available
After birth, mammals acquire a community of bacteria in their gastro-intestinal tract, which harvests energy and provides nutrients for the host. Comparative studies of numerous terrestrial mammal hosts have identified host phylogeny, diet and gut morphology as primary drivers of the gut bacterial community composition. To date, marine mammals have...
Article
Full-text available
The gut microbiota of mammals underpins the metabolic capacity and health of the host. Our understanding of what influences the composition of this community has been limited primarily to evidence from captive and terrestrial mammals. Therefore, the gut microbiota of southern elephant seals, Mirounga leonina, and leopard seals, Hydrurga leptonyx, i...
Thesis
Full-text available
A mammal’s gastro-intestinal tract houses trillions of bacteria, known as the gut microbiota, which is first acquired during birth. This community provides a number of beneficial functions to the host, including breakdown of food and creation of energy, immunity regulation and cellular development. To date, studies on the mammalian gut microbiota h...

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Projects

Projects (3)
Project
The broad target of the research is to identify and characterise the DNA and RNA viruses in Australian wild birds, thereby gaining a better understanding of the avian virome and emerging zoonotic virus infections.