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February 1982 - April 2012
Publications
Publications (206)
The aim of this study is to analyze the effect of implementing a prioritization triage model for admission to an intensive care unit on the outcome of critically ill patients. Retrospective longitudinal study of adult patients admitted to the Intensive Care Unit (ICU) carried out from January 2013 to December 2017. The primary outcome considered wa...
This study evaluated the association of body mass index (BMI) with mortality, length of stay in the intensive care unit (ICU), and length of hospital stay in major burn patients. It was a retrospective cohort study that was originally conducted from January 2017 to January 2020 and that used data from patients admitted to the intensive care unit fo...
Introduction: Different factors related to blood donation can generate situations that
In order to properly evaluate the results of the occupational biomonitoring of chemicals it is necessary to establish reference values for the biomarkers of exposure. The aim of this study was to determine the reference values for methanol in urine of the general population non-occupationally exposed to the xenobiotic under study. Thus, urinary met...
OBJECTIVES
This study sought to analyze the clinical and epidemiologic characteristics of critically ill patients who were denied intensive care unit admission due to the unavailability of beds and to estimate the direct costs of treatment.
METHODS
A prospective cohort study was performed with critically ill patients treated in a university hospit...
Purpose:
To evaluate and compare the effects of topical application and subconjunctival injection of bevacizumab on corneal neovascularization (CNV) in rabbits' eyes after chemical burning of the cornea.
Methods:
The animals were randomly distributed into four groups of five animals. In one group, the drug was instilled, while in another, it was a...
Objectives:
To analyze the direct costs of treating critically ill patients in the intensive care unit of a center specializing in treating burns.
Methods:
This is a prospective cohort study of 180 patients from May 2011 to May 2013. Clinical and demographic data were collected in addition to data for the calculation of severity scores. The cost...
Introduction:
Functional disability is an important health indicator associated with worse quality of life.
Objective:
To estimate the prevalence of functional disability for mobility and to identify factors associated with difficulty going up and down stairs in adults aged 40 years or over.
Methods:
Cross-sectional, population-based study, with...
Objective: To assess the nursing workload using the Nursing Activities Score (NAS) and compare results between patients with and without sepsis at an adult intensive care unit. Methods: Prospective cohort study of patients admitted to the adult intensive care unit from March 10 to December 31, 2008. Clinical data of septic patients were collected i...
To compare clinical characteristics and outcomes of patients with and without acute kidney injury (AKI), to evaluate the incidence and mortality of AKI and predictors of AKI and death in patients hospitalized in an Intensive Care Unit (ICU).
A retrospective study analyzed 152 patients admitted to a single ICU. We assessed age, gender, reason for ho...
Objective:
The nursing workload consists of the time spent by the nursing staff to perform the activities for which they are responsible, whether directly or indirectly related to patient care. The aim of this study was to evaluate the nursing workload in an adult intensive care unit at a university hospital using the Nursing Activities Score (NAS...
Healthcare-associated infections are a major cause of morbidity-mortality among hospitalized patients. The aim of this epidemiological study was to determine mortality and risks related to death in adult patients with healthcare-associated infections admitted to a teaching hospital in one year. Patient data were collected from infection medical rep...
Lactobacillus plantarum has been used in human clinical trials to promote beneficial effects in the immune system, to alleviate intestinal disorders,
and to reduce the risk of cardiovascular disease. It is also involved in many fermentation processes in the food industry.
However, information on the fate of ingested L. plantarum is limited. In this...
OBJECTIVE: to estimate the prevalence of cardiovascular disease risk factors by sex and socioeconomic status. METHODS: cross-sectional population-based representative sample of people aged 40 or older, living in Cambé-PR. Household interviews were conducted, collecting anthropometric measurements and laboratory tests in the first half of 2011. Prev...
A cross-sectional study was conducted with 385 hypertensive patients between 20 and 79 years of age in a family health unit in Londrina, State of Parana, Brazil, to determine the adherence to pharmacological and non pharmacological treatment for arterial hypertension in primary healthcare and identify associated factors. The adherence to pharmacolo...
Com o objetivo de determinar a adesão aos tratamentos farmacológico e não farmacológico da hipertensão arterial na atenção primária e identificar fatores associados, realizou-se estudo transversal com 385 hipertensos de 20 a 79 anos cadastrados em uma unidade de saúde da família de Londrina, Paraná. A adesão ao tratamento farmacológico foi de 59,0%...
Introdução A descentralização dos serviços de hemoterapia foi le-galmente amparada pela Portaria n° 07 de 30 de abril de 1980, do Ministério da Saúde, que preconizava duas ações bási-cas: instituir o Sistema Nacional de Hematologia e Hemo- terapia e criar a Rede Nacional de Centros de Hematologia e Hemoterapia. 1 O Centro de Hematologia e Hemoterap...
Aims:
To identify the prevalence of higher risk of foot ulceration and associated factors among patients with diabetes mellitus (DM) at primary health care services.
Methods:
Individuals with DM, registered at primary health care services in a municipality in southern Brazil, were interviewed and underwent foot examinations. Their risk of ulcera...
Objective:
To describe trends in the incidence of Aids cases according to age and gender from 1986 to 2008.
Methods:
Analyses of Aids trends according to age group and to gender was carried out Londrina, Southern Brazil. The timeframe was divided into two periods (1986-1995 and 1996-2008). Of the polynomial models, it was the first-degree polyno...
Este estudo objetivou verificar a concordância entre resultados de exames laboratoriais autorreferidos e resultados contidos em prontuários de portadores de diabetes mellitus. Trata-se de um estudo transversal realizado em unidades de saúde da família no município de Londrina-PR nas quais foram entrevistados 337 portadores de diabetes mellitus que...
OBJETIVO: analisar indicadores hospitalares nos períodos antes e após a implantação da Gestão Plena do Sistema Municipal em Apucarana-PR.
METODOLOGIA: examinaram-se os indicadores: taxa de internação, média de permanência hospitalar, proporção de evasão e invasão de internações e proporção de internação por clínica. Para analisar as alterações ocor...
BACKGROUND: Chronic Obstructive Pulmonary Disease produces mechanical changes in chest wall and this physical disability reduces the daily life activities and quality of life levels. OBJECTIVES: To assess the effects of an exercise program for Thoracopulmonary Complex Re-Adaptation in the chest wall mobility, exercise capacity and quality of life i...
The objective of the study was to identify factors associated with reports of road accidents, among motorcycle couriers in two medium-sized municipalities in southern Brazil. A self-administered questionnaire was answered by motorcycle couriers that had worked for at least 12 months in this profession. The outcomes analyzed were reports on accident...
OBJECTIVE: This study analyzed the rate of food insecurity among recipients of government assistance and other factors associated with their conditions. METHODS: This cross-sectional study included 421 families from the municipality of Toledo, Paraná State, receiving government assistance. Data was collected from September/2006 to February/2007 dur...
JUSTIFICATIVA E OBJETIVOS: Avaliar a incidência e a mortalidade dos pacientes com lesão renal aguda (LRA), bem como fatores de risco e de óbito em pacientes internados em unidade de terapia intensiva (UTI). MÉTODO: Estudo retrospectivo que analisou 296 pacientes consecutivos internados na UTI em Hospital Universitário. A LRA dialítica foi definida...
The aim of the present study was to verify the effects of fish oil and a soya-based product on inflammatory markers and endothelial function measured by NO in women with the metabolic syndrome (MetS). A total of sixty-five women (mean age: 47·9 (sd 9·98) years) were studied in a 90-d parallel, randomised design. A control group maintained their usu...
Aims: To investigate the determinants of prognosis in patients with severe sepsis and acute renal failure. Methods: We included all patients older than 18 years admitted to the intensive care unit of University Hospital of Londrina (Paraná state) between May 2007 and June 2008 with a diagnosis of severe sepsis or septic shock. Results: We analyzed...
The aim of the study was to evaluate risk factors for infection and sepsis in surgical patients admitted to the intensive care unit (ICU).
Data were prospectively collected from a cohort of surgical patients from January 2005 to December 2007. We analyzed the incidence of infection and sepsis and certain other variables from the pre-, intra-, and p...
Cognitive development is usually assessed by applying objective tests, and the Progress Test (TP-MEd) is one of method used by medical schools. The results can be compared through test equalization. This study assessed the cognitive growth of medicine students at a state university by analysing the TPMed tests in the period of 2004 to 2007, using e...
The present study aimed to assess mortality rates and related demographic factors among indigenous peoples in the State of Mato Grosso do Sul, Central-West Brazil, compared to the State's general population. Mortality rates were estimated based on data obtained from the Health Care Database for Indigenous Peoples and monthly patient care records as...
Metabolic syndrome (MS) is a multifactorial disease involving inflammatory activity and endothelial dysfunction. The aim of the present study was to evaluate the relationship between the changes in lipoperoxidation, in immunological and biochemical parameters and nitric oxide metabolite (NOx) levels in MS patients. Fifty patients with MS (4 males/4...
Purpose: The aim of the study was to evaluate risk factors for infection and sepsis in surgical patients admitted to the intensive care unit (ICU). Materials and Methods: Data were prospectively collected from a cohort of surgical patients from January 2005 to December 2007. We analyzed the incidence of infection and sepsis and certain other variab...
Metabolic syndrome (MS) is a multifactorial disease involving inflammatory activity and endothelial dysfunction. The aim of the present study was to evaluate the relationship between the changes in lipoperoxidation, in immunological and biochemical parameters and nitric oxide metabolite (NOx) levels in MS patients. Fifty patients with MS (4 males/4...
The association of the tumor necrosis factor β (TNF-β) Nco1 genetic polymorphism with susceptibility to sepsis was evaluated in 60 consecutive patients diagnosed with sepsis and in 148 healthy blood donors. Genomic DNA was extracted from peripheral blood cells and a 782 base-pair fragment of the TNF-β gene was amplified by PCR. The PCR products wer...
Metabolic disorders are frequently observed in pediatric patients with renal lithiasis.
Study the metabolic and anatomical alterations and perform the chemical analysis of stones found in children with nephrolithiasis in our region.
A retrospective study on 158 children with evidence of recent renal stone formation was performed. One hundred and ni...
Analysis of APACHE II and SOFA Score at ICU Ordering and Admission. Supplementary Table comparing APACHE II and SOFA scores at the time of ICU ordering and on ICU admission between the two groups of patients (delayed and immediate admission).
When the number of patients who require intensive care is greater than the number of beds available, intensive care unit (ICU) entry flow is obstructed. This phenomenon has been associated with higher mortality rates in patients that are not admitted despite their need, and in patients that are admitted but are waiting for a bed. The purpose of thi...
Este estudo foi realizado numa escola pública da cidade de Londrina, por meio da aplicação do WISC-III a 76 escolares (idade média = 88,39 meses; DP = 4,12), com o objetivo de traçar seu perfil cognitivo. Todos foram avaliados em dois momentos: quando estavam na pré-escola e 18 meses mais tarde, ao final do primeiro ano do Ensino Fundamental. Os re...
Homicides are the main cause of non-natural death in Brazil and studies about them may contribute to their control. The objective of this study was to verify mortality rates due to homicides and legal interventions among young men in the State of Paraná, Brazil, and to identify correlated municipal characteristics. An ecological study was conducted...
There are few studies about the consumption of medication by adults in Brazil. Therefore, the purpose of this research was to identify the profile of medication consumption and associated factors among adults aged 29 to 59 years old. This is a cross-sectional study. The sample included 374 individuals from the area of a family health unit in the ci...
Objectives: The aim of this study was to evaluate similarities and differences in men and women smokers in Smoking Cessation Interventions.
Methods: Smokers (n=167) were recruited from the Smoking Cessation Service and never smokers (n=269) were recruited from the blood donors of Hospital Universitário. The instruments used were a questionnaire, th...
The human immunodeficiency virus type 1 (HIV-1) epidemic in Brazil is spreading to small municipalities as well as the innermost parts of the country and scarce information has been reported on the frequency of HIV-1 resistance-associated mutations in these areas. To determine the frequency and diversity of the HIV-1 antiretroviral resistance-assoc...
A case-control study evaluating seminal zinc level in spinal cord injury (SCI) patients.
Patients with SCI have neurological prostate dysfunction. There are only some indications in the literature that seminal zinc level may be lower in these patients. Seminal zinc is mainly produced by the prostate and, therefore, can be considered to be a marker...
Some sort of restriction of the pouch emptying is supported by many surgeons to allow a sustained weight loss through the use of a ring placed circumferentially around the gastric pouch. Most previous studies focused on the length of the ring, not the actual diameter of the gastric pouch outlet. This study aims to evaluate the association between t...
To verify the effects of fish oil and soy on nitric oxide (NO) and blood pressure in patients with metabolic syndrome (MS).
Sixty women with MS were investigated in a parallel randomized design study. The first group maintained their usual diet; the second group received 25 g/day of soy; the third group received 3 g/day of n-3 fatty acids, and the...
Este trabalho apresenta o perfil das tentativas de suicídio atendidas pelo Centro de Controle de Intoxicações da cidade de Londrina, Paraná, Brasil. Foi realizado um estudo retrospectivo dos casos atendidos entre 1997-2007. As tentativas de suicídio foram significativas entre homens desempregados e mulheres donas-de-casa/aposentadas, e houve associ...
This study presents the profile of suicide attempts using intentional overdose with medicines, treated at the Poison Control Center in Londrina, Paraná State, Brazil. A retrospective study of cases treated from 1997 to 2007 was performed. Suicide attempts were significant among unemployed men, housewives, and retired women, and there was an associa...
OBJECTIVES: The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. METHODS: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis...
Phonemic Awareness is the metalingüistic ability which enables the conscious approach to the phonemic level of speech and the most cognitive manipulation of these representations in this level. In this study we aim at verifying whether the phonemic stimulation in Kindergarten is predictive for writing acquisition in the 1st grade. Eighty-five child...
OBJECTIVES: The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. METHODS: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis...
This paper reports the results of a questionnaire administered to university students, about several questions involving the origin of the Universe and life and biological evolution, as well as questions related to more common scientific themes. As few as between 2.4% (philosophy students) and 14% (geography students) did not accept the theory of e...
OBJETIVO: Avaliar a evolução metabólico-nutricional e a atividade inflamatória em pacientes com obesidade grave submetidos à cirurgia bariátrica. MÉTODOS: Realizou-se um estudo prospectivo em 56 pacientes (50 mulheres e seis homens), apresentando média de idade de 40 +/- 9,9 anos, submetidos à RYGB. Avaliação metabólica e nutricional e da atividade...
To evaluate the application of the Sequential Organ Failure Assessment (SOFA) in describing the severity of organ dysfunctions and the associated mortality rates in critically ill patients at a teaching hospital.
Prospective longitudinal study performed in 1164 adult, critically ill patients who were admitted consecutively into intensive care units...
Brazilian scientific literature on the adverse effects of lead on the general population is still very limited. Lead, a potentially toxic substance, has become a public health problem due to its effects, mainly those affecting the central nervous system and on the synthesis of heme. The aim of this study is to evaluate the level of lead exposure of...
The magnitude of lipoprotein level reduction during the acute-phase response may be associated with the severity and mortality of sepsis. However, it remains to be determined whether low lipoprotein levels can be considered a risk factor for developing sepsis. We aimed to investigate lipoprotein levels as risk factors for sepsis in hospitalized pat...
To assess nutritional and metabolic evolution and inflammatory activity in severe obese patients submitted to bariatric surgery.
This prospective study evaluated 56 patients (50 female and 6 male), mean age 40 + or - 9,9 years, submitted to RYGB. Nutritional, metabolic, and inflammatory parameters were assessed prior to and 12 months postsurgery.
I...
INTRODUCTION: The incidence and prevalence of treated end-stage chronic kidney disease (CKD) patients continue to grow throughout the world. Renal transplantation remains the preferred form of renal substitutive therapy, but given the limited number of donors, dialytic therapies are the most common modalities. OBJECTIVES: To assess a registry of pa...
The incidence and prevalence of treated end-stage chronic kidney disease (CKD) patients continue to grow throughout the world. Renal transplantation remains the preferred form of renal substitutive therapy, but given the limited number of donors, dialytic therapies are the most common modalities.
To assess a registry of patients admitted for renal...
OBJECTIVE: To compare smokers and never smokers in terms of the following: quality of life; BMI; hospitalizations; functionality; family history of mental disorder; tobacco-related diseases; depression; and psychoactive substance use. METHODS: We evaluated 167 smokers enrolled in a smoking cessation program at the Londrina State University Referral...
To compare smokers and never smokers in terms of the following: quality of life; BMI; hospitalizations; functionality; family history of mental disorder; tobacco-related diseases; depression; and psychoactive substance use.
We evaluated 167 smokers enrolled in a smoking cessation program at the Londrina State University Referral Center for Understa...
The diagnosis of human immunodeficiency virus (HIV) in parturient women is used to prevent or change the course of HIV perinatal transmission through the zidovudine prophylaxis regimen. The aims of this study were to determine the prevalence of the HIV infection using the rapid test, to evaluate its acceptance for the diagnosis of HIV infection, an...
The formation of a thermal microclimate within the vehicle during the transport of broilers from farm to slaughterhouse affects the birds' welfare and potentially promotes the development of PSE meat. Thus, the aim of this work was to evaluate the effects of routine commercial practices on the vehicle microclimate formed during transportation of br...
The objective of this study was to identify risk factors associated with pre-term birth among live births in a hospital in Londrina, Paraná State, Brazil. Cases consisted of 328 pre-term births, and controls were 369 births with gestational age greater than 37 weeks. A multiple hierarchical logistic regression analysis was carried out. There was a...
A case-control evaluating seminal citrate in patients with spinal cord injury (SCI).
Several studies have shown neurological prostatic dysfunction in patients with SCI, as confirmed by low levels of seminal prostate-specific antigen (PSA), which is used as a parameter of gland activity. However, seminal citrate, produced almost exclusively by the p...
To determine the prevalence of metabolic syndrome (MetS) in schoolchildren from 6 to 16 years old, while considering their socio-economic status and other potential risk factors.
A cross-sectional study was conducted between April and November of 2005 in a semi-rural city with a total population of 13,000 inhabitants.
The study was conducted in Mar...
To evaluate the reproducibility of water drinking test (WDT) performed at different times of the day, in primary open angle glaucoma (POAG) patients and normal individuals.
Fifteen patients with POAG and 30 normal individuals underwent three WDTs at different times of the day (7 AM, 12 PM, and 5 PM) on 3 different days. Test results in POAG patient...
O Hemonúcleo de Apucarana faz parte da rede pública de bancos de sangue do estado do Paraná e tem como finalidade fornecer hemocomponentes com qualidade aos hospitais a ele conveniados. Com a proposta de atingir as metas do Ministério da Saúde em aumentar a quantidade de doadores espontâneos, o serviço tem se preocupado em buscar subsídios para mel...
The aim of this study was to evaluate associations between seropositivity for IgG and IgM anti-Toxoplasma gondii antibodies and socio-economic and environmental variables in pregnant women of Londrina, state of Paraná, Brazil. We interviewed 492 pregnant women, each of whom answered an epidemiological questionnaire, and collected blood samples for...
This study evaluated the use of the POSSUM (Physiological and Operative Severity Score for Enumeration of Mortality and Morbidity) score for predicting mortality in surgical practice. In this study, 416 surgical patients admitted into ICUs for post-surgical care were analyzed. Both predicted and actual mortality rates were compared, according to fo...