Tibor Nánási

Tibor Nánási
Alkahest, Inc.

PhD, MD

About

49
Publications
6,646
Reads
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429
Citations
Additional affiliations
September 2018 - February 2019
Pázmány Péter Catholic University
Position
  • teacher assistant
Description
  • Electrophysiology
January 2017 - July 2017
Stanford University
Position
  • PhD Student
Description
  • aging, interactome, machine learning, data mining, proteomics
January 2014 - present
Hungarian Academy of Sciences
Position
  • PhD Student
Description
  • aging, interactome, transcriptomics, matlab, electrocorticography, laminar probe, connectome, brain-machine interfaces, machine learning, implants
Education
January 2018 - February 2019
Pázmány Péter Catholic University
Field of study
  • Medical Biotechnology
September 2003 - June 2011
Semmelweis University
Field of study
  • Medicine

Publications

Publications (49)
Article
Full-text available
Blood has been widely investigated to discover biomarkers and gain insights into the biology of aging and age-related diseases. Its protein composition provides insights into complex biological processes, as proteins are often direct regulators of cellular pathways. In clinical trials, selected proteins have been used as primary and secondary endpo...
Conference Paper
Full-text available
In this paper, we investigate the long-term adhesion strength and barrier property of our recently proposed encapsulation stack that includes PDMS-Parylene C and PECVD interlayers (SiO2 and SiC) for adhesion improvement. To evaluate the adhesion strength of our proposed stack, the sample preparation consisted in depositing approximately 25 nm of Si...
Article
Aging is a predominant risk factor for numerous chronic diseases that limit healthspan. Mechanisms of aging are thus increasingly recognized as potential therapeutic targets. Blood from young mice reverses aspects of aging and disease across multiple tissues, which supports a hypothesis that age‐related molecular changes in blood could provide nove...
Article
Full-text available
Aging is a predominant risk factor for several chronic diseases that limit healthspan¹. Mechanisms of aging are thus increasingly recognized as potential therapeutic targets. Blood from young mice reverses aspects of aging and disease across multiple tissues2–10, which supports a hypothesis that age-related molecular changes in blood could provide...
Preprint
Full-text available
Aging is the predominant risk factor for numerous chronic diseases that limit healthspan. Mechanisms of aging are thus increasingly recognized as therapeutic targets. Blood from young mice reverses aspects of aging and disease across multiple tissues, pointing to the intriguing possibility that age-related molecular changes in blood can provide nov...
Article
We investigated the functional network reorganization caused by low-frequency electrical stimulation (LFES) of human brain cortical surface. Intracranial EEG data from subdural grid positions were analyzed in 16 pre-surgery epileptic patients. LFES was performed by injecting current pulses (10 mA, 0.2 ms pulse width, 0.5 Hz, 25 trials) into all...
Article
Full-text available
Stereo-electroencephalography depth electrodes, regularly implanted into drug-resistant patients with focal epilepsy to localize the epileptic focus, have a low channel count (6-12 macro- or microelectrodes), limited spatial resolution (0.5-1 cm) and large contact area of the recording sites (~mm2). Thus, they are not suited for high-density local...
Article
Full-text available
Aggressive manifestations and their consequences are a major issue of mankind, highlighting the need for understanding the contributory factors. Still, aggression-related genetic analyses have so far mainly been conducted on small population subsets such as individuals suffering from a certain psychiatric disorder or a narrow-range age cohort, but...
Article
Full-text available
Rare mutations in the WFS1 gene lead to Wolfram syndrome, a severe multisystem disorder with progressive neurodegeneration and diabetes mellitus causing life-threatening complications and premature death. Only a few association studies using small clinical samples tested the possible effects of common WFS1 gene variants on mood disorders and suicid...
Article
Full-text available
Impairment of executive control functions in depression is well documented, and performance on the Stroop Test is one of the most widely used markers to measure the decline. This tool provides reliable quantitative phenotype data that can be used efficiently in candidate gene studies investigating inherited components of executive control. Aim of t...
Chapter
Full-text available
In the middle of a world economic crisis, studies of biological crisis-survival strategies, which have proven their efficiency over a billion years of evolution, may provide novel ideas and solutions. In this chapter, we summarize our knowledge and the latest results which show that the “crisis of cells,” called stress in biology, and its extreme f...
Article
Full-text available
Recent studies have demonstrated that network approaches are highly appropriate tools for understanding the extreme complexity of the aging process. Moreover, the generality of the network concept helps to define and study the aging of technological and social networks and ecosystems, which may generate novel concepts for curing age-related disease...
Article
Full-text available
The network concept is increasingly used for the description of complex systems. Here, we summarize key aspects of the evolvability and robustness of the hierarchical network set of macromolecules, cells, organisms and ecosystems. Listing the costs and benefits of cooperation as a necessary behaviour to build this network hierarchy, we outline the...
Article
Full-text available
The analysis of network topology and dynamics is increasingly used for the description of the structure, function and evolution of complex systems. Here we summarize key aspects of the evolvability and robustness of the hierarchical network-set of macromolecules, cells, organisms, and ecosystems. Listing the costs and benefits of cooperation as a n...
Article
Essay competition - Biocybernetics special award, 2nd place Természet Világa [Text in hungarian]
Article
Essay competition - Biocybernetics special award, 1st place. Természet Világa [Text in hungarian]

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