Tiago Simões

Tiago Simões
Instituto Politécnico de Leiria | ESTG · MARE – Marine and Environmental Sciences Centre

Doctor of Philosophy
Current research on anthropogenic stressors, using sub-cellular tools to link early effects of polluting chemicals

About

28
Publications
4,443
Reads
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287
Citations
Citations since 2017
14 Research Items
268 Citations
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060
20172018201920202021202220230102030405060

Publications

Publications (28)
Article
This work focuses on understanding the action of a novel seaweed extract with anti-browning functionality in fresh-cut apples. Organic fresh-cut apples were coated by immersion in an aqueous Codium tomentosum seaweed extract (0.5 % w/v), packaged under ambient atmospheric conditions in plastic bags, and stored at 4 ˚C for 15 days. Browning-related...
Article
Full-text available
Sulfoxaflor is an insecticide belonging to the recent sulfoximine class, acting as a nicotinic acetylcholine receptor (nAChRs) agonist. There are few studies regarding sulfoxaflor’s toxicity to non-target organisms. The present study aimed to investigate the acute and sub-lethal effects of sulfoxaflor on Carcinus maenas by addressing survival, beha...
Article
Full-text available
Argan oil is rich in long-chain unsaturated fatty acids (FA), mostly oleic and linoleic, and natural antioxidants. This study addresses the production of low-calorie structured lipids by acidolysis reaction, in a solvent-free system, between caprylic (C8:0; system I) or capric (C10:0; system II) acids and argan oil, used as triacylglycerol (TAG) so...
Article
Full-text available
The seaweed Asparagopsis armata exhibits a strong invasive behavior, producing halogenated compounds with effective biological effects. This study addresses the biochemical responses to sublethal concentrations of A. armata exudate on the marine snail Gibbula umbilicalis whole body and the shrimp Palaemon elegans eyes and hepatopancreas. Antioxidan...
Preprint
The red seaweed Asparagopsis armata exhibits a strong invasive behaviour and is included in the list of the “Worst invasive alien species threatening biodiversity in Europe”. This seaweed has been shown to produce a large diversity of halogenated compounds with effective biological effects, deeply affecting rockpool species. Therefore, the present...
Article
Full-text available
Under controlled laboratory conditions, toxicity data tend to be less variable than in more realistic in-field studies and responses may thus differ from those in the natural environment, creating uncertainty. The validation of data under environmental conditions is therefore a major asset in environmental risk assessment of chemicals. The present...
Article
Degradation rates of two widely used pesticides were assessed, and acute and chronic effects on a standard invertebrate species investigated. An herbicide (Montana®) and fungicide (Bravo500®) formulations were investigated and results were compared to the isolated active substances of each formulation (glyphosate and chlorothalonil, respectively)....
Article
Contaminant discharges, derived from human activities, are major concerns as they exert a continuous ecological pressure on aquatic systems, causing in fact cascading community effects. Although with associated ecological and fitness costs, physiological and biochemical defense mechanisms may restore the organism’s internal balance. Several studies...
Article
The use of an integrative molecular approach can actively improve the evaluation of environmental health status and impact of chemicals, providing the knowledge to develop sentinel tools that can be integrated in risk assessment studies, since gene and protein expressions represent the first response barriers to anthropogenic stress. This work aime...
Article
Full-text available
The use of integrative molecular approaches can aid in a comprehensive understanding of the effects of toxicants at different levels of biological organization, also supporting risk assessment. The present study aims to unravel the toxicity mechanisms of a widely used herbicide to the arthropod Folsomia candida exposed in a natural soil, by linking...
Article
Lipid metabolism involves complex pathways, which are regulated in a similar way across vertebrates. Hormonal and hypolipidemic deregulations cause lipid imbalance from fish to humans, but the underlying mechanisms are far from understood. This study explores the potential of using juvenile brown trout to evaluate the in vivo interferences caused b...
Article
Metals are among the most common environmental pollutants with natural or anthropogenic origin that can be easily transferred through the food chain. Marine gastropods are known to accumulate high concentrations of these metals in their tissues. Gibbula umbilicalis ecological importance and abundant soft tissues, which enables extent biochemical as...
Article
This study aimed to evaluate changes in body composition, specially muscle and liver fatty acid profile in meagre (Argyrosomus regius) fed with different dietary lipid sources and levels, with or without selenium supplementation. Six hundred meagre were fed twice a day, six days per week, with eight experimental diets for 60 days. Diets were a comb...
Article
The Portuguese oyster Crassostrea angulata shows great potential in oyster farming. The conservation of pure populations of this species is important for production diversification and biodiversity preservation. In this way, the zootechnological development for seed hatchery production is extremely important. Broodstock conditioning is a key step i...
Article
The aim of this work was to study the proximate composition and the bioactive profile of Bifurcaria bifurcata. It contains 73.31 ± 0.69% of moisture, 8.57 ± 0.11 g per 100 g dry weight (d.w.) of protein, 5.81 ± 0.14 g per 100 g d.w. of lipid content and 30.15 ± 0.00 g per 100 g d.w. of ash. The polyunsaturated fatty acids were the most abundant fat...
Conference Paper
Enzymes are the most remarkable and highly specialized proteins, presenting in most cases a catalytic efficiency much higher than the majority of synthetic catalyzers, being their industrial production mainly ensured by some species of microorganisms. Marine bacteria present in extreme environments tend to develop adaptation mechanisms to cope with...
Conference Paper
Fatty acids are carbon-rich compounds that are ubiquitous in all organisms and relatively easy to metabolize. Once incorporated in the organism, their biological specificity and the fact that they are transferred from primary producers to higher trophic levels without changing in characteristics, make fatty acids suitable for use as biomarkers. Dif...
Article
Full-text available
This study aims to produce human milk fat substitutes by an acidolysis reaction between lard and the free fatty acids (FFA) from a fish oil concentrate rich in docosahexaenoic acid, in solvent-free media. The immo-bilized commercial lipases from (1) Rhizomucor miehei (Lipozyme RM IM), (2) Thermomyces lanuginosa (Lipo-zyme TL IM) and (3) Candida ant...
Article
Full-text available
Proximate composition (ash, moisture, total protein, and fat contents) and fatty acid profile of Balistes capriscus (grey triggerfish) were assessed over a 6-months period (April to September, 2011) in animals captured along the coast of Peniche (Portugal). High protein (18.9% to 21.4%) and low lipid (0.5% to 0.8%) contents were determined. The hig...
Chapter
Aos olhos da biotecnologia muitos dos organismos marinhos são vistos como biorreatores complexos com um enorme potencial para a síntese de compostos bioativos. Nesta perspetiva, as macroalgas são particularmente interessantes para a pesquisa de compostos bioativos, porque a investigação pode ser desenvolvida em três níveis interdependentes: 1) isol...

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Projects

Projects (3)
Project
Top predator marine species such as sharks tend to accumulate particularly high levels of environmental pollutants. Blue sharks are one of the most widely distributed and most frequently caught shark species worldwide. BLUESHARKER aims to develop a set of tools that can be used to assess effects of ocean contamination on blue sharks' fitness and health, and indirectly infer about the quality of oceans. Information about the accumulation of different pollutants in these sharks and their molecular and physiologic responses will not only be valuable for improved conservation measures but, as this shark species is highly used for human consumption, will be of utmost interest to assess potential risks to human health. With the results of this project we expect to have a better understanding of the organisms' mechanisms to cope with different ocean contamination scenarios, and to develop a biomarker toolbox to be applied in future marine biomonitoring programs.
Project
Internationally, there is a growing trend for the consumption of fresh products, with high nutritional properties, without the addition of chemical additives and with an adequate ease of use suited to citizens' acceleated lifestyle. Algaecoat project intends to demonstrate and validate in the industrial pilot line of Campotec S.A. the conditions for commercial profitability of seaweed ectract applied in minimally processed (MP) apple, pear and in non-controlled atmospheres. This new additive will represent a sustainable option, with natural source, and contribute to the added value of MP products. Previous sudies resulted in a National Patent No. 107369 order titled "Revestimento de origem marinha para aplicação em produtos minimamente processados ou de quarta gama".
Archived project
EnvironOme addresses the use of protein and gene differential expression as tools in pesticide ecological risk assessment and to predict effects of toxicants in the individuals and populations of non-target arthropods. An integrated approach is mandatory to tackle this issue, and with this approach early molecular events involved in toxicant responses responsible for the adverse effects observed at higher levels of organization are deciphered. This project is a collaboration between MARE-IPLeiria and CEF (Portugal), L-ProBE from Ghent University (Belgium), the VU Amsterdam (The Netherlands), and the private company ECT Oekotoxikologie GmbH (Germany), allowing the strengthening of the foundations of ecotoxicoproteomics and ecotoxicogenomics, a mechanistic and holistic approach, not yet fully explored, but with expected significant impacts in several research fields in environmental sciences and regulatory agencies. Project financed by national funding through FCT/MCTES (PIDDAC) and the Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE – Programa Operacional Factores de Competitividade (POFC)