Thomas Vain

Thomas Vain
University of Copenhagen · Department of Plant and Environmental Science

PhD

About

18
Publications
5,008
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551
Citations
Citations since 2017
12 Research Items
486 Citations
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2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100

Publications

Publications (18)
Article
Full-text available
Auxins play an important role in plant physiology and are involved in numerous aspects of plant development, such as cell division, elongation and differentiation, fruit development, and phototropic response. In addition, through their antagonistic interaction with cytokinins, auxins play a key role in the regulation of root growth and apical domin...
Article
Full-text available
The plant hormone auxin, a master coordinator of development, regulates hypocotyl elongation during seedling growth. We previously identified the synthetic molecule RubNeddin 1 (RN1), which induces degradation of the AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) transcriptional repressors INDOLE-3-ACETIC ACID INDUCIBLE3 (IAA3) and IAA7 in planta and strongl...
Article
Full-text available
In a world that will rely increasingly on efficient plant growth for sufficient food, it is important to learn about natural mechanisms of phytohormone action. In this work, the introduction of a fluorophore to an auxin molecule represents a sensitive and non‐invasive method to directly visualise auxin localisation with high spatiotemporal resoluti...
Article
Full-text available
Cytokinins are mobile multifunctional plant hormones with roles in development and stress resilience. Although their Histidine Kinase receptors are substantially localised to the endoplasmic reticulum, cellular sites of cytokinin perception and importance of spatially heterogeneous cytokinin distribution continue to be debated. Here we show that cy...
Article
Full-text available
Tension wood (TW) in hybrid aspen trees forms on the upper side of displaced stems to generate a strain that leads to uplifting of the stem. TW is characterized by increased cambial growth, reduced vessel frequency and diameter, and the presence of gelatinous, cellulose-rich (G-)fibers with its microfibrils oriented parallel to the fiber cell axis....
Preprint
Full-text available
Cytokinins are mobile multifunctional plant hormones with roles in development and stress resilience 1,2. Although cytokinin receptors are substantially localised to the endoplasmic reticulum 3-5, the cellular sites of cytokinin perception continue to be debated 1,6,7. Several cytokinin types display bioactivity 8,9 and recently a cell-specific cyt...
Article
Differentiation of xylem elements involves cell expansion, secondary cell wall ( SCW ) deposition and programmed cell death. Transitions between these phases require strict spatiotemporal control. The function of Populus ERF 139 ( Potri.013G101100 ) in xylem differentiation was characterized in transgenic overexpression and dominant repressor lines...
Article
Full-text available
Auxin phytohormones control most aspects of plant development through a complex and interconnected signaling network. In the presence of auxin, AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) transcriptional repressors are targeted for degradation by the SKP1-CULLIN1-F-BOX (SCF) ubiquitin-protein ligases containing TRANSPORT INHIBITOR RESISTANT 1/AUXIN SIGNAL...
Article
Full-text available
Root hairs are protrusions from root epidermal cells with crucial roles in plant soil interactions. Although much is known about patterning, polarity and tip growth of root hairs, contributions of membrane trafficking to hair initiation remain poorly understood. Here, we demonstrate that the trans-Golgi network-localized YPT-INTERACTING PROTEIN 4a...
Preprint
Auxin phytohormones control most aspects of plant development through a complex and interconnected signaling network. In the presence of auxin, AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) transcriptional repressors are targeted for degradation by the SKP1-CULLIN1-F-BOX (SCF) ubiquitin-protein ligases containing TRANSPORT INHIBITOR RESISTANT 1/AUXIN SIGNAL...
Article
Brassinosteroid (BR) hormone signaling controls multiple processes during plant growth and development and is initiated at the plasma membrane through the receptor kinase BRASSINOSTEROID INSENSITIVE1 (BRI1) together with co-receptors such as BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1). BRI1 abundance is regulated by endosomal recycling and vacuolar tar...
Article
The epidermis of aerial plant organs is thought to be limiting for growth, because it acts as a continuous load-bearing layer, resisting tension. Leaf epidermis contains jigsaw puzzle piece-shaped pavement cells whose shape has been proposed to be a result of subcellular variations in expansion rate that induce local buckling events. Paradoxically,...
Article
Full-text available
The herbicide 2,4-D exhibits an auxinic activity and therefore can be used as a synthetic and traceable analog to study auxin-related responses. Here we identified that not only exogenous 2,4-D but also its amide-linked metabolite 2,4-D-Glu displayed an inhibitory effect on plant growth via the TIR1/AFB auxin-mediated signaling pathway. To further...
Article
Full-text available
The establishment and maintenance of controlled auxin gradients within plant tissues are essential for a multitude of developmental processes. Auxin gradient formation is co-ordinated via local biosynthesis and transport. Cell to cell auxin transport is facilitated and precisely regulated by complex endomembrane trafficking mechanisms that target a...
Article
Full-text available
Significance Within plants, controlled gradients of the hormone auxin are essential for development. These gradients are achieved through intracellular polar positioning of auxin transporter proteins, such as PIN-FORMED proteins (PINs), at the plasma membrane, thus guiding the direction of auxin transport. The establishment and maintenance of PIN p...
Conference Paper
Background / Purpose: The ubiquitin-proteasome system (UPS) plays an important role in the signaling pathways involved in the regulation of plant growth and development, especially those mediating phytohormone responses. In recent years, chemical genomics, or the use of small molecules to perturb target protein function, has emerged as a powerful...
Article
Full-text available
Plant growth and organ formation depend on the oriented deposition of load-bearing cellulose microfibrils in the cell wall. Cellulose is synthesized by a large molecular weight (MW) Cellulose Synthase Complex (CSC), which comprises at least three distinct cellulose synthases (CESAs). Cellulose synthesis in plants or bacteria also requires the activ...
Conference Paper
Full-text available
Umeå Plant Science Centre (UPSC) was formed in 1999 by merging the Department of Plant Physiology at Umeå University and the Department of Forest Genetics and Plant Physiology at the Swedish University of Agricultural Sciences (SLU). Chemical Biology Consortium Sweden (CBCS) is cooperation between Karolinska Institute (Stockholm), Umeå University a...

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