Thomas Pattyn

University of Antwerp | UA · Collaborative Antwerp Psychiatric Institute (CAPRI)

Background The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive.Methods Using a data-driven, case-centered app...

The most common form of tinnitus is a subjective, auditory, and distressing phantom phenomenon. Comorbidity with depression is high but other important psychiatric disorders such as anxiety disorders have received less attention. The current paper reviews the literature on the associations between tinnitus and anxiety disorders and the underlying p...

The pharmaceutical industry is an important partner in mental health care. To provide ethical advice that will help psychiatrists build a balanced relationship with the pharmaceutical industry. In this article we present the current advisory principles that have been developed by the Flemish Psychiatric Association (Vlaamse Vereniging voor Psychi...

Introduction: Concern for medical doctors’ health has been widely recognized over the past ten years. EFPT is aware of the heterogeneity of support set up for doctors in distress and recognizes the need for further cross-Europe research. This project aims to gather information and carry out research in order to improve services for physician health...

This paper provides an overview of the research in the field of consultation and liaison psychiatry, conducted at the Collaborative Antwerp Psychiatric Research Institute (University of Antwerp). In the past decade, chronic fatigue syndrome (CFS) has been the major research topic. Regarding this, we elaborate on the following projects in the first...

Background Inconsistent findings regarding the pathophysiology of panic disorder (PD) could result from clinical heterogeneity. Identifying subtypes could enhance insights into the neurobiological substrates of PD. Methods An emotional faces fMRI paradigm was used in a group of PD patients (n=73) and healthy controls (n=58). The overall PD group w...

Vergeleken met de algemene bevolking zouden patiënten na een opname in een psychiatrisch ziekenhuis een hoger risico hebben op verschillende ongunstige gebeurtenissen. Voorgaande studies vertonen methodologische beperkingen omtrent inclusie van stoornissen en uitkomstmaten. Onderzoeksvraag: In welke mate hebben mensen na een eerste opname in een p...

Aims: The prevalence of panic disorder (PD) reportedly is up to fivefold higher in people with tinnitus than it is in the general population. The brain networks in the two conditions overlap but the pathophysiological link remains unclear. In this study the electrophysiological brain activity is investigated in adults with non-pulsatile tinnitus w...

Objective To investigate the impact of childhood trauma on the clinical course of panic disorder. Method Longitudinal data of 539 participants with a current panic disorder were collected from the Netherlands Study of Depression and Anxiety (NESDA). Childhood trauma was assessed with a structured interview and clinical course after two years with...

Objective: To investigate the impact of childhood trauma on the clinical course of panic disorder and possible contributing factors. Method: Longitudinal data of 539 participants with a current panic disorder were collected from the Netherlands Study of Depression and Anxiety (NESDA). Childhood trauma was assessed with a structured interview and...

Introduction Concern for medical doctors’ health has been widely recognized over the past ten years. EFPT is aware of the heterogeneity of support set up for doctors in distress, recognizing the need for further cross-Europe research. Aims The EFPT “HELP Project” was designed to investigate psychiatry trainees’ perceptions of and attitudes towards...

Introduction The literature on the neurobiology of emotional processing in panic disorder (PD) remains inconsistent. Clinical heterogeneity could be causing this. Objective To investigate differences in brain activity between PD and healthy controls using the emotional faces fMRI paradigm. Aims To elucidate neurobiological mechanisms underlying e...

Meer wetenschap in de Vlaamse psychiatrie B. SaBBe TijdSchr GeneeSk 2013; 69: 800-806 Geachte redactie, De "Vlaamse Vereniging voor Assistenten Psychiatrie" (VVAP) las met veel aandacht het artikel van professor Sabbe (1). Net zoals de auteur ervaart de VVAP het onvoldoende besef van de noodzaak tot een versteviging van het wetenschappelijke karak-...

The subtypes showed significant differences on several clinical characteristics such as the Anxiety Sensitivity Index (ASI), the FEAR questionnaire, WHODAS functioning scores, comorbidity, suicide attempts and medication use. There were no significant differences with regard to the demographic variables, the number of chronic somatic diseases or ch...

Onderzoek naar differentiatie, de determinanten en het lange termijnverloop van het respiratoir versus non respiratoir subtype met inbegrip van diagnostische stabiliteit en comorbiditeit. Wijze: Prospectieve, longitudinale, naturalistische cohortstudie (NESDA) Aantal: 2981 deelnemers, waarvan 670 met paniekstoornis en 652 controles Parameters: • De...