Thirunavukkarasu Arun BabuAll India Institute of Medical Sciences · Pediatrics
Thirunavukkarasu Arun Babu
MBBS (JIPMER), MD Pediatrics (JIPMER), DAA(CMC), MBA (HM), Fellow in Neonatology (Cumming School of Medicine University of Calgary, Canada)
Professor & Head,
Dept of Pediatrics, AIIMS, Mangalagiri,
Assoc Editor - BMC Pediatrics,
Visit my page www.drarunbabu.in
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347
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Introduction
Professor & Head, Dept of Pediatrics, AIIMS, Mangalagiri, India.
Author of 34 books including best selling "Pediatrics for Medical graduates (Elsevier), "TARGET Pediatrics (Wolters Kluwer Lippincott)", "TARGET JIPMER (Peepee)", and "Review of NEET-PG (Paras)" Book series.
Winner of "Outstanding Medico of the year" Award at IHPA 2019,/ Innovator/Patent holder
Assoc Editor BMC Pediatrics, Intl' Pubmed indexed journal, EB member - JIGIMS. For collaboration: babuarun@yahoo.com & www.drarunbabu.in
Additional affiliations
Education
January 2015 - January 2016
January 2013
April 2006 - March 2009
Publications
Publications (347)
A child in middle childhood presented with six episodes of left-sided parotitis in the last 6 months. This was associated with erythematous circinate patches of the dorsal aspect of the tongue suggestive of geographic tongue. His growth was normal with no underlying nutritional deficiencies. Relevant investigations ruled out immune conditions like...
Caudal regression syndrome (CRS), also known as caudal dysgenesis, consists of a constellation of caudal developmental anomalies along with soft-tissue anomalies. The severity of its spectrum ranges from lumbosacral agenesis to isolated absence of coccyx. The pathophysiology of the disease is not fully known due to its rarity. In this case report,...
An infant girl presented with multiple blisters followed by peeling of the skin over the entire body for 5 days with a prodrome of fever and cough. The child had dysmorphic facies, growth faltering and developmental delay. The ultrasonogram of the abdomen showed multiple small cysts in both kidneys with increased echogenicity and loss of corticomed...
An infant girl presented with multiple blisters followed
by peeling of the skin over the entire body for 5 days
with a prodrome of fever and cough. The child had
dysmorphic facies, growth faltering and developmental
delay. The ultrasonogram of the abdomen showed
multiple small cysts in both kidneys with increased
echogenicity and loss of corticomed...
The article analyses the recent amendment by the National Medical Commission (NMC) in India, capping the number of undergraduate medical seats in high-performing states, which has sparked a debate. With a healthcare system catering to the diverse needs of 1.4 billion people, regional disparities in healthcare personnel distribution have emerged, es...
The second edition of this book has been meticulously designed to cover the core pediatric competencies outlined by the NMC’s Competency-based Medical Education (CBME) curriculum. This book will ensure that students are learning the most relevant and up-to-date information necessary. Specifically tailored to cover the undergraduate syllabus, this b...
BACKGROUND
Results from randomized controlled trials (RCTs) are considered to have the highest level of evidence. Recruiting children for RCT is challenging and greatly influenced by the perception and decision of parents.
OBJECTIVES
To find the reasons for refusal to participate in RCT.
DESIGNS
Questionnaire-based qualitative study.
MATERIALS A...
Kartagener’s syndrome (KS) is a rare autosomal recessive genetic condition causing disruption to ciliary movement, leading to the triad of sinusitis, situs inversus, and bronchiectasis. Mutations in genes such as DNAI1 and DNAH5 increase susceptibility to recurrent sinopulmonary infections, infertility and errors with the left-right body orientatio...
Conventional stethoscope is a useful clinical examination tool to aid evaluation of the underlying clinical condition, especially respiratory and cardiac illnesses, even before definitive imaging studies are performed. Auscultation with a stethoscope becomes highly challenging when wearing personal protective equipment (PPE) because the hood of the...
Goldenhar syndrome, also recognised as oculo-auriculo-vertebral spectrum, is a very rare condition distinguished by a diverse array of clinical abnormalities affecting the ocular, auditory, vertebral and various organ systems. The pathophysiology of this condition is not fully elucidated due to its inherent genetic variability and rarity. In this r...
A 5-year-old girl presented with complaints of fever, left-sided hemiparesis, and left upper motor neuron facial nerve palsy following oral polio booster dose vaccination. She had a past history of fever with altered sensorium with complete resolution at 3 years of age. Cerebrospinal fluid evaluation and stool examination were inconclusive. MRI wit...
A BSTRACT
Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome, also known as Mullerian aplasia/Mullerian agenesis, is characterized by the absence of the uterus and upper two-thirds of the vagina in women who have normal ovarian function and secondary sexual characteristics. The syndrome occurs at a rate of approximately 1 in every 4500–5000 females. It...
A defect in the oesophageal hiatus can result in the herniation of the stomach or other abdominal organs into the thoracic cavity, known as a hiatal hernia. These hernias are uncommon in infants and children, and their symptoms can be vague and non-specific, posing challenges for even experienced clinicians to make a diagnosis. Regardless of the ca...
A BSTRACT
Background
The lockdown due to the COVID-19 pandemic has affected the lives of children and resulted in behavioral and emotional disturbances in children. This study was planned to identify the prevalence of these problems in Indian children. The aim of the study was to estimate the effect of lockdown on the neurobehavioral profile of ch...
Abdominal mass in a toddler is a common condition encountered in clinical practice. The nature of abdominal mass in toddlers can be a developmental cyst or benign and malignant tumours from various intraabdominal organs. Round blue cell tumours arising from the kidney, adrenals, pancreas, and liver in toddlers present as abdominal masses and are po...
PIM3 and compared among the groups since factors like sepsis, metabolic milieu, and blood pressures might have influenced the results [4]. Nevertheless, considering the recognized adverse effects associated with the infusion of heparinized saline for maintaining arterial patency, this randomized controlled trial has definitely provided early insigh...
A total of 320 children, aged 1 to 14 years were observed
to ascertain the prevalence of face mask usage and the
factors affecting the same. 67% of children used face
masks, but only 25% of them used them correctly. Factors
such as age, type of school, socioeconomic status,
maternal education, history of allergic diseases, COVID
vaccination status...
BACKGROUND
COVID-19 vaccination was started on January 3, 2022, among children aged 15–-18 years with Covaxin vaccination. Subsequently, Corbevax was approved for age groups up to 12 years of age since March 16, 2022.
OBJECTIVES
To know the incidence and spectrum of adverse effects following immunization (AEFI) for this newly approved COVID-19 vac...
Hepatitis A is a common cause of acute infectious hepatitis in children, transmitted through the faeco-oral route. Although mostly self-limiting, cholestasis is a rare but known complication of acute hepatitis A in children. This report presents an adolescent girl who developed cholestatic features following hepatitis A infection and successful tre...
Background
Needle pain due to routine vaccination is an important factor contributing to low vaccine adherence and immunization coverage. Prophylactic oral analgesics can address this important issue of needle pain related to vaccination. Paracetamol and mefenamic acid are commonly used nonsteroidal anti-inflammatory drugs for pain relief, but ther...
Dermatological conditions associated with socio‐cultural and religious practices, known as “cultural dermatoses,” are commonly seen in medical practice. This article presents seven cases of children who underwent skin branding for jaundice in Southern India. Skin branding, a traditional healing method, involves applying heated objects to cause thir...
BACKGROUND
The COVID-19 pandemic greatly impeded the provision of public healthcare within a healthcare system that was already under considerable strain. Routine patient care services were impacted during that time, leading to the promotion of telemedicine as a means of maintaining uninterrupted healthcare services. Telemedicine involves the utili...
Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condit...
Herlyn-Werner-Wunderlich (HWW) syndrome OHVIRA syndrome (Obstructed HemiVagina Ipsilateral Renal Agenesis) is rare type of Mullerian duct anomaly, with uterine didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Usually presenting in post-pubertal adolescent girls presenting as pain abdomen or pelvic masses on the side of the obstruct...
Anemia in pregnancy is a common condition having a significant effect on the outcome of pregnancy. A thorough understanding of epidemiology along with proper clinical history, clinical examination and focussed investigations will help to diagnose the cause of anemia early during pregnancy. We report a case of 22-year-old primigravida who presented...
Acardiac twin is a rare complication of monozygotic twin pregnancies. It accounts for 1% of monochorionic twin gestations with an incidence of 1 in 35,000 births. We report a rare case of acardiac twin with sacrococcygeal teratoma in a monochorionic twin gestation in view of rare incidence and diagnostic challenge.
Wilson’s disease (WD) is an inherited autosomal recessive disorder of copper metabolism, characterised by an excess accumulation of free copper in the liver, brain, and eyes. Patients with WD commonly present with hepatic or neurological symptoms, whereas pancytopenia is an unusual initial presentation of this disease. We are presenting the case of...
Cryptorchidism is a common congenital anomaly and is associated with numerous pathological changes in gross morphology and histology of testis. Adenomatous hyperplasia of rete testis and sertoli cell only syndrome is rare benign histological changes in undescended testis. We report a case of undescended testis showing adenomatous hyperplasia of ret...
Clinical diagnosis of grouped vesicular lesions in pediatric age group needs a detailed history and meticulous dermatological assessment of the morphology. Lymphangioma circumscriptum (LC) is one rare condition suspected with classic clinical presentation. Frog spawn appearance and black vesicles are two clues for making a clinical diagnosis. Here,...
Risperidone is commonly used in postnatal mothers for depression and psychotic symptoms in spite of little data on its safety profile in neonates. It is reported previously that 6 mg/day can be used in mothers without having any untoward in breastfed neonates. Excretion of risperidone is dependent on the enzyme CYP2D6 whose activity varies as per i...
Carpal tunnel syndrome (CTS) is the most prevalent compressive focal mononeuropathy brought on by median nerve compression, and common manifestations include pain in the wrist joint, decreased sensations along the distribution of the median nerve, a reduction in two-point discrimination, nighttime awakening, and, in more advanced stages, thenar mus...
Background: Mistreatment of women during pregnancy and childbirth by healthcare workers is a common issue in both private and public sector health facilities in India. Improving the quality of maternity care in these sectors is crucial for promoting institutional births and ensuring positive birth experiences. This study aims to develop guidelines...
Snoring is noisy breathing during sleep and is a symptom of sleep disordered breathing. Persistent snoring is an alarming symptom requiring extensive examination of the oral and respiratory tract. There are various causes of nasal obstruction in children. External nasal examination with nasal speculum and nasal endoscopy helps to identify the origi...
Presacrococcygeal mass in a neonate always creates diagnostic confusion due to various etiologies. Large masses interfere with labour management and development of pelvic spine and organs. Awareness about prenatal radiological diagnosis of sacral lesion in fetus is needed for earlier and better management of mass in postnatal period. Here, we repor...
Spinal Muscular Atrophy (SMA) is an autosomal recessive Motor Neuron Disease (MND) with mutation of Survival motor neuron 1 (SMN1) gene located in chromosome 5(5q13.2) characterized by diffuse proximal and distal muscle weakness. Here the authors report a case of SMA in a 3 months old male infant with hypotonia of proximal muscles in both upper lim...
Cystic lesion of abdomen in a toddler is a rare condition. It can be developmental, infectious, benign or malignant in nature. The site of origin may be from intrabdominal organs, omentum, mesentery, retroperitoneum, vasculature and lymphatics. They often present as acute abdominal pain, abdominal distension or constipation. Radiology and histopath...
A new head cover device has been developed to allow healthcare workers to use a stethoscope while wearing personal protective equipment (PPE). The device consists of a hood that fits over the head, with earplugs on the inside and hollow tubing on the outside that is connected to a one-way valve. The stethoscope is attached to the valve, allowing th...
Background
Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in neonatal period. Most of neonatal sepsis-related morbidity and mortality can be prevented by early diagnosis and treatment with appropriate antimicrobial agents. Micro-erythrocyte sedimentation rate (m-ESR) i...
This article recounts a poignant interaction between the author and a mother of a child with cerebral palsy. The mother's remarkable strength and optimism in the face of adversity deeply moved the author, leading to a tearful moment which prompted a comforting response from the mother. The ongoing debate regarding whether doctors are allowed to dis...
Posterior mediastinal tumours in children are difficult to diagnose due to non-specific clinical symptoms. Most of them are neurogenic in origin. However, large pulmonary neoplasms in children may also present as posterior mediastinal masses and may be misinterpreted as neurogenic tumour. We report a case of 6-year female child with recurrent vomit...
Background:
Hepatic transaminase (HT) elevation is frequently seen in children with scrub typhus (ST), but the clinical implication of this common finding is not known.
Objective:
To describe the clinical profile and outcome of pediatric ST with elevated hepatic transaminase.
Methods:
In this prospective cohort study, all children < 12 years o...
Expanding the language coverage of speech technology has the potential to improve access to information for many more people. However, current speech technology is restricted to about one hundred languages which is a small fraction of the over 7,000 languages spoken around the world. The Massively Multilingual Speech (MMS) project increases the num...
Background:
Various therapeutic iron preparations are available in the market, which differ in their pharmacokinetic and safety profiles. There is insufficient evidence regarding the superior safety or efficacy of one over the other.
Objectives:
To study the effects of iron preparations on various parameters like hemoglobin, mean corpuscular vol...
Background
Skin dimples at specific sites of the body at birth are a clue to underlying congenital malformation and intimate the need for extensive evaluation. A midline dimple in the spinal region may be a sign of occult spinal dysraphism in a neonate.
Methods
A toddler presented with clinical symptoms and signs of acute paraparesis. The child al...
p>This work utilizes a wearable phonocardiogram belt for acquiring signals from remote areas. Four sequential methodologies are undergone in the proposed work for resilience, and effectiveness. Intelligent, and accurate FHR monitoring. At first, the noise and artifacts are removed by performing two levels pre-processing methodology method. The low...
Objectives
Protection and promotion of breastfeeding has been a challenge for all healthcare team members during the COVID-19 pandemic. It is important for all healthcare workers (HCWs) to be aware of the existing guidelines and to counsel the parents and family members regarding the same. We used a structured training module using analyse, design,...
Van Wyk–Grumbach syndrome is a rare presentation of long-standing prepubertal hypothyroidism in a female characterized by bilateral polycystic ovaries, delayed skeletal growth, and isosexual precocious puberty. We report a case of juvenile primary hypothyroidism presenting as an abdominal mass due to huge bilateral ovarian cysts which responded to...
Background:
This study was planned to estimate the effect of lockdown on psychosomatic problems and sleep of children and their association with screen the time during the lockdown.
Methods:
A cross-sectional study was conducted among 1-12-year-old children at a tertiary care hospital in South India. A pre-validated questionnaire with 20 related...
Background
Since the beginning of the novel coronavirus disease in Wuhan city of China in 2019 and its spreading worldwide and taking the form of a pandemic, many healthcare workers (HCWs) were affected by coronavirus disease 2019 (COVID-19) infection. Though we have used many types of personal protective equipment (PPE) kits while taking care of C...
Malaria is a global burden and requires accurate and early diagnosis. WHO has recommended that all clinically suspected cases should have parasitological confirmation for definitive treatment. There are other many methods which are expensive and require high skills. Hence, incorporation of reliable methods into automated hematology analysers will h...
COVID-19 is a novel coronavirus infection that can cause a severe respiratory
illness and has been declared a pandemic by the WHO. Compared with adults,
most pediatric patients with COVID-19 are mostly asymptomatic, whereas others AQ3
show distinctive characteristics in clinical presentation and imaging. Most of the
pulmonary lesions were ambiguous...
Abdominal lump in a child is a common and worrisome clinical presentation which necessitates many radiological and hematological investigations for diagnosis. Though differential diagnoses are many, detailed history taking and thorough clinical examination can help in diagnosing the organ involved before doing investigations. We are presenting a ca...
BACKGROUND: COVID-19 (Coronavirus disease-19) is an ongoing pandemic. COVID vaccine administration in adults has provided some degree of protection from infection but children are still susceptible So, we have to be prepared to handle COVID-19 infection in children by training our healthcare workers by updating both their knowledge and skills. We d...
Background
Multisystem inflammatory syndrome in children (MIS-C) is a post-infectious sequelae of acute COVID-19 infection affecting children. This study was done over a period of 12 months from December 2020 to November 2021 to describe the clinical presentation, laboratory abnormalities, and outcome of children with MIS-C.
Methods
Seventy-eight...
Fever and difficulty in breathing in a child are common symptoms encountered in routine practice. Often, the underlying cause will be infectious etiology due to bacterial, viral, or tuberculous. However, a malignancy of the paraspinal soft tissue region mimicking infectious disease clinically in a child is challenging to diagnose and treat. Here, w...
This case report describes a 12-year-old boy who presented with high-grade fever, joint pain, abdominal pain, and general weakness. The Widal test showed positive results with ‘O’ and ‘H’ antibody titers of 1:320. Additionally, the blood culture report confirmed the growth of Salmonella typhi, leading to the diagnosis of enteric fever. An abdominal...
Current self-supervised learning algorithms are often modality-specific and require large amounts of computational resources. To address these issues, we increase the training efficiency of data2vec, a learning objective that generalizes across several modalities. We do not encode masked tokens, use a fast convolutional decoder and amortize the eff...
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Pilomatricoma is relatively an uncommon benign cutaneous neoplasm predominantly in the first two decades of life. It is often misdiagnosed by non-dermatologists due to a lack of knowledge about this tumour. However, it can be easily diagnosed by a pathologist if classical histopathological features are present. We are presenting this case as there...
Background: Coronavirus disease 2019 (COVID-2019) was declared as a pandemic on March 11, 2020 by the WHO. This disease was complicated by its association with an opportunistic fungal infection, termed as COVID-19-associated mucormycosis (CAM). CAM is well described in adults, but only a few case reports and series were published about pediatric CA...
Background
Scrub typhus is a mite-borne infection caused by the bacterium, Orientia tsutsugamushi . It is re-emerging in many parts of South East Asia, particularly in rural India. Although no age group is immune to this infection, scrub typhus in neonates is rarely suspected and reported. Here, we report a neonate with scrub typhus who was initial...
Questions
Question (1)
I submitted an article to a journal one year back. The status changed to 'Editorial review' immediately after submission and stays so till date. I sent 4 emails to editor requesting 'status update' and I did not get any reply. I sent an email recently informing them about withdrawal of my article and still no reply from them. Should I continue sending reminders or just wait for their reply or can I proceed with submission to another journal? Need your opinion.