Theophilus Lakiang

Christian Medical College Vellore | CMCH-Vellore · Centre for Stem Cell Research

Background: Aedes aegypti and Aedes albopictus are primary vectors of emerging or re-emerging arboviruses that threaten public health worldwide. Many efforts have been made to develop interventions to control these Aedes species populations. Still, countries in the Latin America and the Caribbean (LAC) region struggle to create/design/develop sust...

Early adolescence is the period of the emergence of most mental disorders contributing significantly to the mental health burden globally, including India. The major challenges in India are early identification of mental health problems, treatment gap, lack of professionals, and interventions that address the same. Our review aimed to assess the ef...

Maternal undernutrition can lead to protein-energy malnutrition, micronutrient deficiencies, or anemia during pregnancy or after birth. It remains a major problem, despite evidence-based maternal-nutrition interventions happening on ground. We conducted a scoping review to understand different strategies and delivery mechanisms to improve maternal...

Background: Neonatal pneumonia remains a significant contributor to infant mortality in India and responsible for increased prevalence of infant deaths globally. Objective: To identify risk factors associated with neonatal pneumonia and its mortality in India. Study design: A systematic review was conducted including both analytic study design...

Background Neonatal pneumonia is one of the leading factors contributing to neonatal mortality. The objective of this review was to identify the barriers associated with case management of neonatal pneumonia in India by conducting a scoping review. Methods Nine databases (PubMed, ProQuest, Ovid Medline, CINAHL, Web of Science, EMBASE, IndMED, SCOP...

Background Children born to high-risk pregnancies are more likely to experience adverse health outcomes later in life. As estimated, 15% of all pregnancies are at risk of various life-threatening conditions leading to adverse maternal and foetal outcomes. Millennium Development Goal resulted in the global reduction of maternal death from 390,000 to...

Purpose: Despite 55% children aged 0-6 months being exclusively breastfed in India, 0.26 million children die each year from diarrhoea and pneumonia that can be prevented through early initiation of and exclusive breastfeeding (EIBF). A study was conducted to assess the factors associated with EIBF in 20 villages from the District Khagaria (State B...

Plant derivatives, such as anthocyanin‐rich phytochemicals, have been reported to elicit a positive effect on lipid profile. Therefore, the aim of this study was to systematically review and meta‐analyze the effects of Aronia consumption on lipid profiles, blood pressure, and biomarkers of inflammation in randomized controlled trials. A systematic...

Background Chronic obstructive pulmonary disease continues to be the important contribution toward disability, death, and burden in the costs of health care globally. Economic impact of COPD is attributed with substantial direct and indirect costs. COPD affects the productivity of work that poses a burden on the employers and also on individuals in...

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and safety of pertussis vaccination in pregnancy for preventing whooping cough in early infancy.

Introduction India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. Methods and anal...

Introduction: Fifty-three percent of Indian under-5 deaths occur during the neonatal age group. Recognizing that there is a lack of illustrated district-level data on neonatal mortality in India, we mapped this to visually highlight districts where neonatal health issues require the most attention. Methods: District-level estimates of 596 Indian...

Introduction India contributes to the highest number of neonatal deaths globally. It also has the greatest number of pneumonia-related neonatal deaths in the developing world. We aim to systematically review the evidence for the factors associated with mortality due to neonatal pneumonia in the Indian context, to address the lack of consolidated ev...

Introduction India contributes to the highest neonatal deaths globally. Case management is said to be the cornerstone of pneumonia control. Much of the published evidence focuses on children aged 1 to 59 months. This scoping review, thus, aims to identify the treatment options for and barriers to case management of neonatal pneumonia in India. Met...

Introduction India accounted for more neonatal deaths (estimated at 696 000) than any other country, as of 2015. Of these , most neonatal deaths due to infections can be attributed to pneumonia which accounts for 16% of all neonatal mortalities (2010). Despite simple, inexpensive case management strategies being available, pneumonia continues to ca...

Systematic reviews enable researchers to identify, analyze and synthesize relevant research into a single body of evidence, while presenting their methods and findings in a transparent and explicit manner. The process of identifying relevant studies requires reviewers to screen thousands of database search results, looking for appropriate studies t...