Theodosia BartzelaUniversitätsklinikum Carl Gustav Carus Dresden · Department of Orthodontics
Theodosia Bartzela
DDS, MSc, Dr. med. dent., PhD
About
99
Publications
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Introduction
I am Professor Theodosia Bartzela, Head of the Orthodontic Department at TU Dresden. I hold a DDS from Thessaloniki, an MSc from Harvard, a Ph.D. from Radboud University, and specializations in Pediatric Dentistry (Tufts) and Orthodontics (Freiburg). I have led orthodontic departments in Germany and held academic roles in Greece and the Netherlands. My research focuses on craniofacial anomalies, and fostering collaborations across disciplines.
Additional affiliations
December 2022 - present
Position
- Professor
Description
- Professor, Head of the Department
Publications
Publications (99)
Recently, several reviews have been published on the effects of medications on bone physiology and the clinical side effects in orthodontics. However, the effects of medications on the rate of orthodontic tooth movement have not been evaluated.
A systematic literature review on the effects of medications and dietary supplements on the rate of exper...
In this chapter, we reviewed the effects of medication on bone physiology and orthodontic tooth movement (OTM). The chapter is organized according to the classes of medication, such as synthetic analogues of eicosanoids, analgesics, corticosteroids, insulin, relaxin, as well as calcium and calcium regulators. We looked into well-controlled animal s...
Care of individuals with syndromes affecting craniofacial and dental structures are mostly treated by an interdisciplinary team from early childhood on. In addition to medical and dental specialists that have a vivid interest in these syndromes and for whom these syndromes are of evident interest, experts of scientific background—like molecular and...
![Time course (0–21 days) of metal ion concentration [µg/L] (A: Ni, B:...](publication/382831113/figure/fig2/AS:11431281270591627@1723230430503/Time-course-0-21-days-of-metal-ion-concentration-g-L-A-Ni-B-Au-C-Pd-and-D_Q320.jpg)
![Box and whisker plots of metal ion concentrations [μg/L] of Ni, Au, Pd,...](publication/382831113/figure/fig3/AS:11431281270767730@1723230431649/Box-and-whisker-plots-of-metal-ion-concentrations-mg-L-of-Ni-Au-Pd-and-Hg-in-saliva_Q320.jpg)
Background: This longitudinal prospective study aimed to assess orthodontic patients’ immune system response to metal ion release in saliva. Methods: Thirty adult patients (18–35 years) were equally divided into three groups: groups at the end (G1) and beginning (G2) of multibracket appliances (MBA) treatment and a non-treated control group (G3). P...
![Figure 2. Time course (0-21 days) of metal ion concentration [µg/L] (A:...](profile/Nusha-Paschaei/publication/382889784/figure/fig1/AS:11431281270133426@1722946257877/Time-course-0-21-days-of-metal-ion-concentration-g-L-A-Ni-B-Au-C-Pd-and-D_Q320.jpg)
Aims
This study aimed to evaluate the visual improvement of resin infiltration of white spot lesions (WSL) during orthodontic treatment with the multibracket appliance (MBA) compared to fluoride varnish.
Methods
Patients aged 12–17 years with at least one WSL with an International Caries Detection and Assessment System (ICDAS) score of 1–2 during...
Objectives
In light of the growing interest in orthodontic care and its effectiveness in Germany, part 2 of this multicenter cohort study evaluated patient-reported outcomes such as oral health-related quality of life (OHRQoL), oral hygiene habits, oral health beliefs, and potential influencing factors.
Methods
Of 586 patients screened from seven...
Aim
The oral microenvironment contributes to microbial composition and immune equilibrium. It is considered to be influenced by dietary habits. Phenylketonuria (PKU) patients, who follow a lifelong low‐protein diet, exhibit higher prevalence of oral diseases such as periodontitis, offering a suitable model to explore the interplay between diet, ora...
Background/Objectives
Tooth agenesis (TA) is among the most common malformations in humans. Although several causative mutations have been described, the genetic cause often remains elusive. Here, we test whether whole genome sequencing (WGS) could bridge this diagnostic gap.
Methods
In four families with TA, we assessed the dental phenotype using...
This longitudinal study aimed to evaluate facial growth and soft tissue changes in infants
with complete unilateral cleft lip, alveolus, and palate (CUCLAP) at ages 3, 9, and 12 months. Using
3D images of 22 CUCLAP infants, average faces and distance maps for the entire face and specific
regions were created. Color-coded maps highlighted more signi...
Cleft lip and palate patients require complex interdisciplinary treatment, including max-illary expansion and secondary alveolar bone grafting. However, the evidence on these treatment procedures and outcomes is lacking. Therefore, this study aimed to survey the subjective observations of European maxillofacial surgeons and orthodontists on the max...
Objectives
The aim of this study was to compare the prevalence of oral diseases (caries, periodontal disease, enamel defects) between patients with phenylketonuria (PKU), their siblings, and a matched control group.
Materials and methods
A total of 109 patients with PKU, 14 siblings of PKU patients, and 100 healthy individuals aged 6 to 68 years w...
The aim of this study was to evaluate angular and positional changes in the second (M2) and third molars (M3) of orthodontically treated patients undergoing a first molar (M1) extraction. A retrospective longitudinal study with a sample of 152 pre-and post-treatment panoramic radiographs was conducted. Thirty-nine patients (51.3%) were orthodontica...
Objectives:
To evaluate the angular and positional changes of the maxillary second (M2) and third molars (M3) after orthodontic premolar extraction treatment according to patient skeletal classification and growth pattern.
Materials and methods:
Panoramic radiographs of patients treated with extraction of the first or second premolars (n = 116)...
Objectives The study aimed to survey current strategies against enamel demineralization during multibracket therapy (MBT) and guide a prevention concept based on existing scientific evidence.
Materials and Methods The survey comprised questions on the prevention and management of white spot lesions (WSL). The questionnaire was sent via email to ort...
Background: There are little scientific data on fully automated Peer Assessment Rating (PAR); this study compares a number of PAR scoring methods to assess their reliability.
Objectives: This investigation evaluated PAR scores of plaster, 3D printed, and virtual digital models scored by specialist orthodontists, dental auxiliaries, undergraduate d...
The treatment management of patients with hemifacial microsomia (HM) includes both surgical and nonsurgical approaches and depends primarily on the degree of deformity of the facial and skeletal structures. In this context, the combined efforts of the maxillofacial surgeon, the orthodontist, and the prosthodontist are essential for a satisfactory f...
Objectives: To clinically characterize patients and family members with Cleft Lip and/or Palate (CL/P) and associated congenital malformations or syndromes and propose possible inheritance patterns.
Materials and Methods: An observational study of patients with CL/P, including medical and family history and intra- and extra-oral examination of the...
The aim of this study was to create a new reliable setup to evaluate commercially available orthodontic wires used during orthodontic treatment. The setup includes various techniques applied for testing metal alloy materials. The materials were tested under extreme conditions to simulate their behavior in the mouth. The alloy composition of each wi...
Aims
Orthodontic care and its effectiveness have increasingly become the focus of political and public attention in the recent past. Therefore, this multicenter cohort study aimed to report about the effectiveness of orthodontic treatments in Germany and to identify potential influencing factors.
Methods
A total of 586 patients from seven German s...
Syndromes affecting craniofacial and dental structures account for one-third of the congenital anomalies. Early diagnosis and treatment guided by an interdisciplinary team are of vital importance not only for an optimal outcome but also because these syndromes are associated often with life-threatening conditions. However, the affected craniofacial...
Patients with an orofacial cleft (OFC) need complex treatment and require long-term and collective decisions from the multidisciplinary team. These patients may have an associated congenital malformation or syndrome. There are conditions like learning or psychiatric disorders or heart diseases that can be diagnosed later in life. Therefore, the cle...
Supplementary information 2.
42 pedigrees of patients with orofacial cleft. Type of cleft, laterality, associated anomalies, microsymptoms, and deaths shortly after birth or still births of affected individuals have been indicated.
OBJECTIVES:
The aims of this retrospective longitudinal study were to present the incidence of external apical root resorption (EARR) in the maxillary anterior teeth of patients with complete unilateral cleft lip and palate (CUCLP) and to evaluate the influence of orthodontic treatment variables on the development of EARR.
MATERIAL AND METHODS:
Fo...
Purpose
The literature is scarce on studies comparing secondary alveolar bone graft (SABG) performed early at approximately 5‐6 years and at the conventional time at 9‐11 years. This systematic literature review (SLR) aimed at comparing clinical outcomes after two different timings of SABG in children with unilateral and bilateral cleft lip and pal...
Purpose
To evaluate and form a comprehensive understanding of the effect of patient age on bone remodeling and consequently on the rate of orthodontic tooth movement (OTM).
Methods
A systematic search in PubMed and Embase from 1990 to December 2017 was performed and completed by a hand search. Prospective clinical trials which investigated the rat...
Abstract
Background: Patients with syndromes affecting the craniofacial and dental structures are treated mainly by an interdisciplinary team. The orthodontist is involved in the team since the child's birth. The objective of orthodontic treatment during the neonatal period is to align the maxillary alveolar segments, relieve the upper airway obstr...
OBJECTIVES: The aims of this retrospective longitudinal study were to present the incidence of external apical root resorption (EARR) in the maxillary anterior teeth of patients with complete unilateral cleft lip and palate (CUCLP) and to evaluate the influence of orthodontic treatment variables on the development of EARR.
MATERIAL AND METHODS: Fo...
Introduction: Solitary median maxillary central incisor (SMMCI) syndrome is a rare and complex disorder that occurs in 1:50,000 live births. The developmental defects are mainly located in the craniofacial midline, namely: the midline cleft lip palate or congenital nasal malformation. Some of the associated anomalies belong to the holoprosencephaly...
Age estimation in 5-16 year old children by measurement of open apices: North German formula
The aims of this study were to test the accuracy of Cameriere et al.’s European formula on a sample of North German children based on dental age (DA) for chronological age (CA) assessment and to adapt the formula used, in case of regional peculiarities of...
Aim:
Aim of the study was to compare how six different sealants resisted thermal, mechanical, and chemical loading in vitro.
Materials and methods:
In all, 120 extracted human, nondecayed molars were divided into six groups (20 samples each) and embedded in resin blocks. The buccal surfaces of the tooth samples were polished and divided into thr...
Background
Hereditary sensory and autonomic neuropathy type VIII is a rare autosomal recessive inherited disorder. Chen et al. recently identified the causative gene and characterized biallelic mutations in the PR domain-containing protein 12 gene, which plays a role in the development of pain-sensing nerve cells. Our patient’s family was included...
Tooth agenesis and orofacial clefts represent the most common developmental anomalies and their co-occurrence is often reported in patients as well in animal models. The aim of the present systematic review is to thoroughly investigate the current literature (PubMed, EMBASE) to identify the genes and genomic loci contributing to syndromic or non-sy...
Kieferorthopädische Zahnbewegung sind bei gesundem Parodont in jedem Alter möglich, wenn eine gute häusliche Mundhygiene durchgeführt wird und der Hauzahnarzt und sein Team mit professionellen Zahnreinigungen unterstutzend mitwirken. Es gibt unterschiedlichen Wünsche und Fragestellungen von Patient und Hauzahnarzt, die durch eine kieferorthopädisch...
Objective:
To characterize tooth agenesis patterns and their overall prevalence in patients with complete unilateral cleft lip and palate (CUCLP).
Design:
Panoramic radiographs of 115 non-syndromic patients (78 males and 37 females) with CUCLP (85 patients had a cleft on the left and 30 on the right) from the Cleft Palate Craniofacial Unit in Ni...
a r c h i v e s o f o r a l b i o l o g y x x x (2 0 1 3) x x x – x x x a b s t r a c t Objective: To characterize tooth agenesis patterns and their overall prevalence in patients with complete unilateral cleft lip and palate (CUCLP). Design: Panoramic radiographs of 115 non-syndromic patients (78 males and 37 females) with CUCLP (85 patients had a...
Inleiding. Bij patiënten met een complete bilaterale cheilognathopalatoschisis worden frequent andere aangeboren afwijkingen waargenomen.
Over voorkomen van syndromen bij deze patiëntengroep zijn weinig gegevens bekend. Doel van het onderzoek was het retrospectief
inventariseren van bijkomende aangeboren afwijkingen en syndromen bij patiënten met e...
Yardsticks have been developed to measure dental arch relations in cleft lip and palate (CLP) patients as diagnostic proxies for the underlying skeletal relationship. Travelling with plaster casts to compare results between CLP centres is inefficient so the aim of this study was to investigate the reliability of using digital models or photographs...
Yardsticks have been developed to measure dental arch relations in cleft lip and palate (CLP) patients as diagnostic proxies for the underlying skeletal relationship. Travelling with plaster casts to compare results between CLP centres is inefficient so the aim of this study was to investigate the reliability of using digital models or photographs...
In this longitudinal study, the craniofacial morphology and evaluated soft tissue profile changes, at 6 and 12 years of age in patients with complete bilateral cleft lip and palate (CBCLP) were compared. Lateral cephalograms from 148 patients with CBCLP, treated consecutively at three European cleft centers, Gothenburg (n (A) = 37), Nijmegen (n (B)...
The aim of this study was to compare craniofacial morphology and soft tissue profiles in patients with complete bilateral cleft lip and palate at 9years of age, treated in two European cleft centres with delayed hard palate closure but different treatment protocols. The cephalometric data of 83 consecutively treated patients were compared (Gothenbu...
Objective : To compare two scoring systems: the Huddart/Bodenham system (HB system) and the Bauru-BCLP yardstick (BCLP yardstick), which classify treatment outcome in terms of dental arch relationships in patients with complete bilateral cleft lip and palate (CBCLP). The predictive value of these scoring systems for treatment outcome was also evalu...
Objective:
To compare two scoring systems: the Huddart/Bodenham system (HB system) and the Bauru-BCLP yardstick (BCLP yardstick), which classify treatment outcome in terms of dental arch relationships in patients with complete bilateral cleft lip and palate (CBCLP). The predictive value of these scoring systems for treatment outcome was also evalu...
Stavropoulos D, Bartzela T, Bronkhorst E, Mohlin B, Hagberg C. Dental agenesis patterns of permanent teeth in Apert syndrome. Eur J Oral Sci 2011; 119: 198–203. © 2011 Eur J Oral Sci
Dental agenesis may either occur as an isolated trait (non-syndromic) or as a component in a congenital syndrome. The aim of the present study was to identify the prev...
The aim of this study was to compare craniofacial morphology and soft tissue profiles in patients with complete bilateral cleft lip and palate at 9 years of age, treated in two European cleft centres with delayed hard palate closure but different treatment protocols. The cephalometric data of 83 consecutively treated patients were compared (Gothenb...
Inleiding.Bij patiënten met een complete bilaterale cheilognathopalatoschisis worden frequent andere aangeboren afwijkingen waargenomen. Over voorkomen van syndromen bij deze patiëntengroep zijn weinig gegevens bekend. Doel van het onderzoek was het retrospectief inventariseren van bijkomende aangeboren afwijkingen en syndromen bij patiënten met ee...
Abstract Schisis, als gecombineerde bilaterale cheilo-gnatho-palato-schisis of een (unilateraal) onderdeel hiervan, is de meest voorkomende
aangeboren orofaciale afwijking.
Dental agenesis may be present in an isolated familiar manner, or occur as a part of a syndrome.To date, this clinical trait seems to have been overlooked in patients with Crouzon syndrome.The aim of the present study was to investigate dental agenesis and dental agenesis patterns in a population of persons with Crouzon syndrome in Sweden. Serial p...