Theodore Beauchaine

Theodore Beauchaine
University of Notre Dame | ND · Department of Psychology

Ph.D.

About

193
Publications
99,513
Reads
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13,342
Citations
Citations since 2016
85 Research Items
8156 Citations
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201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
Additional affiliations
June 2013 - present
The Ohio State University
Position
  • Professor (Full)
August 2011 - May 2013
Washington State University
Position
  • Professor (Full)
September 2000 - June 2010
University of Washington Seattle
Position
  • Research Assistant

Publications

Publications (193)
Article
Now over 10 years old, the Research Domain Criteria (RDoC) has gained impressive traction in the adult psychopathology literature, but enthusiasm among child and adolescent psychopathologists lags somewhat behind. We consider possible reasons why RDoC has not been embraced fully in the child and adolescent literatures. We emphasize common, interrel...
Article
Every generation of psychopathologists is confronted with critical issues that, if left unaddressed, impede progress in both science and practice. As just one example, progress in psychiatry was hindered for many years by problems with diagnostic validity. Surmounting these problems required painstaking efforts to operationalize diagnostic criteria...
Article
In recent years, irritability has received increasing attention among mental health professionals given its transdiagnostic associations with diverse forms of psychopathology. In contrast to other emotional states and traits, however, literature addressing associations between irritability and related temperament and personality constructs is limit...
Article
Low resting respiratory sinus arrhythmia (RSA) is observed in many mental health conditions, including anxiety disorders, mood disorders, schizophrenia spectrum disorders, disruptive behavior disorders, and nonsuicidal self-injury, among others. Findings for RSA reactivity are more mixed. We evaluate associations between RSA reactivity and empirica...
Article
Full-text available
Self-inflicted injury (SII) in adolescence is a serious public health concern that portends prospective vulnerability to internalizing and externalizing psychopathology, borderline personality development, suicide attempts, and suicide. To date, however, our understanding of neurobiological vulnerabilities to SII is limited. Behaviorally, affect dy...
Chapter
Parent training (PT) is effective in treating early onset conduct problems (CPs), particularly when focused on altering reinforcement systems that support aggression and emotional lability. We describe PT, as well as augmenting effects of additional treatment components (e.g., child training). Effective PT alters family dynamics to increase positiv...
Article
Full-text available
Symmetrical bifactor models are frequently applied to diverse symptoms of psychopathology to identify a general P factor. This factor is assumed to mark shared liability across all psychopathology dimensions and mental disorders. Despite their popularity, however, symmetrical bifactor models of P often yield anomalous results, including but not lim...
Article
Despite nonoverlapping diagnostic criteria, internalizing and externalizing disorders show substantial comorbidity. This comorbidity is attributable, at least in part, to transdiagnostic neuroaffective mechanisms. Both unipolar depression and externalizing disorders are characterized by structural and functional compromises in the striatum and its...
Article
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Studies of 16p11.2 copy number variants (CNVs) provide an avenue to identify mechanisms of impairment and develop targeted treatments for individuals with neurodevelopmental disorders. 16p11.2 deletion and duplication phenotypes are currently being ascertained; however, sleep disturbances are minimally described. In this study, we examine sleep dis...
Article
Objective Test differential prospective prediction of growth in externalizing behavior, including oppositional defiant disorder (ODD), conduct disorder (CD) and substance use disorders (SUDs), by earlier hyperactive-impulsive (HI) versus inattentive (IN) symptoms of attention-deficit/hyperactivity disorder (ADHD). Method Participants in the Longit...
Article
Growth mixture modeling (GMM) and its variants, which group individuals based on similar longitudinal growth trajectories, are quite popular in developmental and clinical science. However, research addressing the validity of GMM-identified latent subgroupings is limited. This Monte Carlo simulation tests the efficiency of GMM in identifying known s...
Article
News of a videogame that received FDA clearance to treat youth with attention-deficit hyperactivity disorder (ADHD) garnered a great deal of media attention and raised questions about the role of digital cognitive training programs for treatment. In order for clinicians and clients to understand this news for the purposes of making treatment decisi...
Article
Full-text available
Lay summary written for open access journal ("The ScienceBreaker") based on original paper: Beauchaine, T. P., Ben-David, I. & Bos, M. ADHD, financial distress, and suicide in adulthood: A population study. Sci. Adv. 6, 1-9 (2020).
Article
Children of fathers with antisocial personality disorder (ASPD) are at risk for devel- oping delinquency, and both biological and environmental mechanisms contribute. In this study, we test parasympathetic nervous system (PNS) function as a vulner- ability/sensitivity attribute in predicting intergenerational associations between fa- thers' antisoc...
Article
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Children with higher socioemotional competence are more likely to build constructive relationships with others and experience more positive adjustment outcomes in later periods. Securely attached children are likely to develop better socioemotional competence, but genetic moderation of associations between attachment and later socioemotional compet...
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The original version of this article unfortunately contained a mistake. The supplementary material was not captured to our commentary article.
Article
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Sleep problems are common among children with neurodevelopmental disorders (NDDs). We review sleep disturbance in three major NDDs: autism spectrum disorder, Down syndrome, and fetal alcohol spectrum disorder (FASD). We review associations with functional impairment, discuss how patterns of sleep disturbance inform understanding of etiology, and th...
Article
Full-text available
Attention-deficit/hyperactivity disorder (ADHD) exerts lifelong impairment, including difficulty sustaining employment, poor credit, and suicide risk. To date, however, studies have assessed selected samples, often via self-report. Using mental health data from the entire Swedish population ( N = 11.55 million) and a random sample of credit data (...
Preprint
Full-text available
Behavioral tasks (e.g., Stroop task) that produce replicable group-level effects (e.g., Stroop effect) often fail to reliably capture individual differences between participants (e.g., low test-retest reliability). This “reliability paradox” has led many researchers to conclude that most behavioral tasks cannot be used to develop and advance theori...
Preprint
Symmetrical bifactor models are frequently applied to diverse symptoms of psychopathology to identify a general P factor. This factor is assumed to mark shared liability across psychopathology dimensions and mental disorders. Despite their popularity, however, symmetrical bifactor models often yield anomalous results, including but not limited to n...
Data
Supplemental Tables for Burns et al. (2020).Application of the Bifactor S - 1 Model to Multisource Ratings of ADHD/ODD Symptoms: An appropriate bifactor model for symptom ratings. Journal of Abnormal Child Psychology, 48, 881-894.
Code
These materials provide the Mplus Model Code for Figure 1A, 1B, 1C, and 1D. These materials also provide the global fit indices (Table S1) and the standardized factor loadings (Table S2) from the confirmatory factor analyses for the four models. Figure 1A = Model 1A (correlated factors model) Figure 1B = Model 1B (bifactor S-1 model) Figure 1C = Mo...
Article
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Almost all forms of psychopathology, including personality disorders, are arrived at through complex interactions among neurobiological vulnerabilities and environmental risk factors across development. Yet despite increasing recognition of etiological complexity, psychopathology research is still dominated by searches for large main effects causes...
Article
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The commentaries by Burke and Johnston (this issue), Eid (this issue), Junghänel et al. (this issue), and Willoughby (this issue) on Burns et al. (this issue) provide useful context for comparing three latent variable modeling approaches to understanding psychopathology—the correlated first-order syndrome-specific factors model, the bifactor S – 1...
Article
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Several studies show altered heart rate variability (HRV) in autism spectrum disorder (ASD), but findings are neither universal nor specific to ASD. We apply a set of linear and nonlinear HRV measures—including phase rectified signal averaging—to segments of resting ECG data collected from school-age children with ASD, age-matched typically develop...
Article
Trait impulsivity—defined by strong preference for immediate over delayed rewards and difficulties inhibiting prepotent behaviors—is observed in all externalizing disorders, including substance use disorders. Many laboratory tasks have been developed to identify decision-making mechanisms and correlates of impulsive behavior, but convergence betwee...
Article
Full-text available
The symmetrical bifactor model is often applied to attention-deficit/hyperactivity disorder (ADHD)-hyperactive/impulsive (HI), ADHD-inattentive (IN), and oppositional defiant disorder (ODD) symptoms, but this model frequently yields anomalous or inadmissible results. An alternative model, the bifactor S – 1 model, is more appropriate for examining...
Article
Full-text available
Sexual discounting, which describes delay discounting of later protected sex vs. immediate unprotected sex (e.g., sex now without a condom vs. waiting an hour to have sex with a condom), is consistently linked to sexual risk behavior. Estimates suggest that over two-thirds of HIV transmissions occur between individuals in committed relationships, b...
Article
Full-text available
In the original publication of the article, the corresponding author was processed incorrectly. The corresponding author for this article should be: Woo-Young Ahn.
Article
Non-suicidal self-injury (NSSI) affects 15-20% of adolescents—disproportionately girls—and is a strong predictor of eventual suicide attempts and suicide. Many girls now initiate NSSI before age 10. These early-starters exhibit greater frequency of NSSI, use more diverse methods, and are hospitalized more often, yet there are no empirically support...
Article
Emotion dysregulation and emerging psychopathology: A transdiagnostic, transdisciplinary perspective - Volume 31 Special Issue - Theodore P. Beauchaine, Dante Cicchetti
Chapter
Traditionally, studies of personality disorder development have focused on (1) whether adult symptoms are expressed among children and adolescents, and if so (2) ages of onset at which full syndrome criteria are met. Although such studies are necessary and important, they provide limited understanding of etiopathophysiology—the complex and interact...
Chapter
As described in the literature for many years, a sizable number of children with hyperactive-impulsive and combined subtypes/presentations of ADHD—especially males—progress to more serious externalizing syndromes across development. Such outcomes include oppositional defiant disorder, conduct problems, delinquency, substance use disorders, and in s...
Article
Full-text available
The objective was to determine the longitudinal associations between callous-unemotional (CU) and oppositional defiant (OD) behaviors from first to fourth grade for Spanish children. Four possible outcomes were evaluated: (1) CU behaviors in first grade predict increases in OD behaviors in the fourth grade, controlling for OD behaviors in the first...
Chapter
Two theoretical perspectives—functionalism and constructionism—predominate modern research on emotion. In this introductory chapter, we describe these perspectives, and offer points of convergence and divergence. We pay special attention to common misconceptions about functionalism, and to strengths and limitations of each perspective. Functionalis...
Book
Emotion dysregulation—which is often defined as the inability to modulate strong affective states including impulsivity, anger, fear, sadness, and anxiety—is observed in nearly all psychiatric disorders. These include internalizing disorders such as panic disorder and major depression, externalizing disorders such as conduct disorder and antisocial...
Chapter
Over the past two decades, emotion dysregulation—defined as the inability to dampen strong emotional responses in the service of goal-directed behavior—has emerged as a consistent, transdiagnostic vulnerability to psychopathology. Although specific forms of dysregulated emotion vary across disorders (e.g., exuberance, anger and related approach emo...
Article
As early as infancy, caregivers’ facial expressions shape children's behaviors, help them regulate their emotions, and encourage or dissuade their interpersonal agency. In childhood and adolescence, proficiencies in producing and decoding facial expressions promote social competence, whereas deficiencies characterize several forms of psychopatholog...
Chapter
In recent years, it has become increasingly clear that common forms of psychopathology derive from complex interactions among neurobiological vulnerabilities and environmental adversities. These interactions can alter neurobehavioral development to yield progressively intractable forms of psychopathology across childhood and adolescence. This chapt...
Article
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In the past 35 years, developmental psychopathology has grown into a flourishing discipline that shares a scientific agenda with contemporary psychiatry. In this editorial, which introduces the special issue, we describe the history of developmental psychopathology, including core principles that bridge allied disciplines. These include (1) emphasi...
Article
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Although emotion dysregulation (ED) is a core symptom of borderline personality disorder (BPD), tests of associations between ED and aggression and violence—which are common to BPD—are sparse. The authors evalu- ated mediating effects of an autonomic vulnerability to ED on links between BPD symptoms and (a) reactive aggression, (b) proactive aggres...
Article
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Recently in this journal, Weeland et al. (2018) published a thought-provoking article reporting moderating effects of children's serotonin transporter-linked polymorphisms ( 5-HTTLPR ) on negative parenting during prevention with the Incredible Years series. Participants were parents and young children of 387 families enrolled in the Observational...
Article
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Objectives: We sought to identify subgroups of individuals based on patterns of psychological health problems (PH; e.g., depressive symptoms, hazardous drinking) and family maltreatment (FM; e.g., child and partner abuse). Method: We analyzed data from very large surveys of United States Air Force active duty members with romantic partners and c...
Article
Lay summary: Evaluation of autism spectrum disorder (ASD) incorporates both caregiver and clinician perspectives of symptoms, and disagreement between these perspectives could lead to poorer outcomes for families. Using data from 2,759 families, we show that caregiver-clinician agreement on ASD symptoms is poorer for children with higher cognitive...
Article
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Despite non-overlapping criterion sets, conduct disorder and depression co-occur at much higher rates than expected by chance. Contemporary model-based approaches to explaining heterotypic comorbidity use factor analysis and its variants to evaluate inter-relations among symptoms in large population-based and twin samples. These analyses invariably...
Article
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Low resting RSA, and to a lesser extent excessive RSA reactivity to emotion evocation, are observed in many psychiatric disorders characterized by emotion dysregulation, including syndromes spanning the internalizing and externalizing spectra, and other conditions such as nonsuicidal self-injury. Nevertheless, some inconsistencies exist. For exampl...
Article
This phase of the NIH Science of Behavior Change program emphasizes an "experimental medicine approach to behavior change," that seeks to identify targets related to stress reactivity, self-regulation, and social processes for maximal effects on multiple health outcomes. Within this framework, our project focuses on interpersonal processes associat...
Article
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Abnormal patterns of sympathetic- and parasympathetic- linked cardiac activity and reactivity are observed among externalizing children, and mark deficiencies in central nervous system regulation of behavior and emotion. Although changes in these biomarkers have been observed following treatment, mechanisms remain unexplored. We used MEMORE—a new a...
Article
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Neural responses to monetary incentives among self-injuring adolescent girls—CORRIGENDUM - Colin L. Sauder, Christina M. Derbidge, Theodore P. Beauchaine
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In psychopathology research, endophenotypes are a subset of biomarkers that indicate genetic vulnerability independent of clinical state. To date, an explicit expectation is that endophenotypes be specific to single disorders. We evaluate this expectation considering (1) recent advances in psychiatric genetics, (2) recognition that transdiagnostic...
Article
Full-text available
Delay discounting—often referred to as hyperbolic discounting in the financial literature—is defined by a consistent preference for smaller, immediate rewards over larger, delayed rewards, and by failure of future consequences to curtail current consummatory behaviors. Previous research demonstrates (1) excessive delay discounting among individuals...
Article
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Previous studies have examined the neural correlates of emotion regulation and the neural changes that are evoked by music exposure. However, the link between music and emotion regulation is poorly understood. The objectives of this review are to (1) synthesize what is known about the neural correlates of emotion regulation and music-evoked emotion...
Article
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This article reviews evidence that trait impulsivity-expressed early in life as the hyperactive-impulsive and combined presentations of attentiondeficit/hyperactivity disorder (ADHD)-is a bottom-up, subcortically mediated vulnerability to all externalizing disorders. This vulnerability arises from deficient mesolimbic dopamine responding, which imb...
Article
Full-text available
High sensitivity and reactivity to behaviors of family members characterize several forms of psychopathology, including self-inflicted injury (SII). We examined mother-daughter behavioral and psychophysiological reactivity during a conflict discussion using nonlinear dynamics to assess asymmetrical associations within time-series data. Depressed, S...
Article
Motivational models of psychopathology have long been advanced by psychophysiologists, and have provided key insights into neurobiological mechanisms of a wide range of psychiatric disorders. These accounts emphasize individual differences in activity and reactivity of bottom-up, subcortical neural systems of approach and avoidance in affecting beh...
Article
Full-text available
Trait impulsivity, which is often defined as a strong preference for immediate over delayed rewards and results in behaviors that are socially inappropriate, maladaptive, and short-sighted, is a predisposing vulnerability to all externalizing spectrum disorders. In contrast, anhedonia is characterized by chronically low motivation and reduced capac...
Article
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A new generation of comorbidity research in the era of neuroscience and Research Domain Criteria - Volume 28 Issue 4pt1 - Theodore P. Beauchaine, Dante Cicchetti
Article
Absolute pitch (AP) is the ability to identify and/or produce specific music notes without a reference tone from the Western tonal system. Functional imaging studies show that AP is subserved by a network of interconnected neural structures including the left posterior dorsolateral frontal cortex (DLFC), the bilateral planum temporale (PT), and oth...
Article
Social deficits are fundamental to autism spectrum disorder (ASD), and a growing body of research implicates altered functioning of the autonomic nervous system (ANS), including both sympathetic and parasympathetic branches. However, few studies have explored both branches concurrently in ASD, particularly within the context of social interaction....
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Prior research comparing children of same-sex and heterosexual couples is limited by methodological issues such as not including male same-sex couples and not using appropriate comparison groups of heterosexual parents. The current study addresses these limitations by examining differences in demographic characteristics between adult children of fe...
Article
Among adults, depression is associated with reduced vagal activity, as indexed by high frequency heart rate variability [HF-HRV]), which correlates inversely with depression severity. Available evidence in depressed children and adolescents remains to be reviewed systematically. A search of the literature was performed to identify studies reporting...
Article
Full-text available
Borderline personality disorder (BPD) and antisocial personality disorder (ASPD) are among the most debilitating psychiatric conditions. Behaviors and traits associated with these disorders can have profound influences on those surrounding the affected individual. Accordingly, researchers have begun to examine effects of these symptoms on parent-ch...
Chapter
Psychophysiology—the study of interactions between physiological systems and psychological states and traits—has a long history of use in psychopathology research. Developmental psychopathologists routinely use psychophysiological methods to investigate how individual-level vulnerabilities (e.g., neural, autonomic) interact with environmental risk...
Article
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Abstract Rates of self-inflicted injury (SII) among adolescents have risen in recent years, yet much remains to be learned about the pathophysiology of such conduct. Behaviorally, self-injuring adolescents report high levels of both impulsivity and depression. Aberrant neural responding to incentives, particularly in striatal and prefrontal regions...
Chapter
INTRODUCTION Psychophysiology encompasses studies of phenomena that cut across many areas of behavioral science, and can be especially useful in developmental psychology and developmental psychopathology research, where assessment of physiological functions often provides access to internal states that are not observable using other methods. The st...
Chapter
Among boys, about one-third who exhibit severe attention deficit ⁄ hyperactivity disorder (ADHD) in preschool follow a developmental trajectory to early-onset conduct disorder (CD) in later childhood and adolescence. Moreover, the vast majority of adolescent boys with early-onset CD also meet criteria for ADHD. Although trait impulsivity, a predisp...
Article
There is a growing scientific interest in the psychophysiological functioning of children living in low-socioeconomic status (SES) contexts, though this research is complicated by knowledge that physiology-behavior relations often operate differently in these environments among adults. Importantly, such research is made more difficult because SES m...
Article
Effortful control (EC) is a form of self-regulation characterized by inhibition of dominant responses in favour of more adaptive subdominant responses. In the present study, temperamental antecedents in infancy were examined in relationship to toddler EC. Parents reported on infant temperament at 6, 8, 10, and 12months, using the regulatory capacit...
Article
Full-text available
The objective was to determine if the latent structure of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) symptoms is best explained by a general disruptive behavior factor along with specific inattention (IN), hyperactivity/impulsivity (HI), and ODD factors (a bifactor model) whereas the latent structure of...
Article
Full-text available
Although the dexamethasone suppression test (DST) has limited use as a marker of depression given inadequate sensitivity and specificity, it marks prospective risk for suicide among adults. However, few studies have examined associations between the DST, suicidal ideation, and self-inflicted injury (SII) among adolescents, even though SII is the si...
Article
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This paper reviews central nervous system substrates and autonomic correlates of emotion dysregulation, and offers several suggestions for future research. Studies conducted in the last two decades indicate that effective emotion regulation requires efficient top-down, cortically-mediated regulation of bottom-up, subcortically-mediated individual d...
Article
The objective was to determine if the latent structure of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) symptoms is best explained by a general disruptive behavior factor along with specific inattention (IN), hyperactivity/impulsivity (HI), and ODD factors (a bifactor model) whereas the latent structure of...
Chapter
Peripheral psychophysiological techniques, through which autonomic nervous system activity and reactivity are measured, have been used for at least a century to make inferences about psychopathological processes. In appropriately designed experiments, cardiovascular reactivity, including heart rate and its sympathetic and parasympathetic components...
Article
Pervasive social difficulties among individuals with autism spectrum disorder (ASD) are often construed as deriving from reduced sensitivity to social stimuli. Behavioral and neurobiological evidence suggests that typical individuals show preferential processing of social (e.g., voices, faces) over nonsocial (e.g., nonvocal sounds, images of object...