Thammasin Ingviya

• Doctor of Philosophy
• Johns Hopkins University

Background Asthma exacerbations remain a significant global health issue despite advances in management. Fine particulate matter (PM2.5, particles ≤ 2.5 μm in diameter) is a known trigger for asthma exacerbations. However, studies on the acute effects of PM2.5, particularly in regions with relatively low pollution levels, are limited. This study ex...

Objective: In 2021, the Thai Ministry of Public Health implemented policies known as “Factory Accommodation Isolation” (FAI) to provide care for confirmed patients with coronavirus disease-2019 (COVID-19). FAIs were established to alleviate strain on the healthcare system. However, the effectiveness of FAIs in alleviating COVID-19 remains unclear d...

วัตถุประสงค์ เพื่อประมาณระดับความรู้เรื่องการดูแลแบบประคับประคองของประชากรในจังหวัดหนึ่งของภาคใต้ ประเทศไทย และระบุปัจจัยที่เกี่ยวข้องกับความรู้เรื่องการดูแลแบบประคับประคอง วัสดุและวิธีการ เป็นการศึกษาวิจัยแบบภาคตัดขวางเก็บข้อมูลในกลุ่มตัวอย่างอายุ 18 ปีขึ้นไป ใช้แบบสอบถามเพื่อประเมินความรู้เกี่ยวกับการดูแลแบบประคับประคอง วิเคราะห์ข้อมูลด้วยสถิติเพ...

Particulate matter (PM) concentration in southern Thailand has increased significantly due to open crop burning within the southeast Asian sub-region. This study aimed to explore the trend and relationship between PM and meteorological features in southern Thailand. Also, estimate the PM 2.5 when monitoring sites measure PM 10. Data on PM concentra...

OBJECTIVES: This study aimed to explore the prevalence of silicosis and chest radiographic features among sandstone engravers in Lopburi province, Thailand. MATERIALS AND METHODS: This retrospective descriptive study was conducted in February 2021 through individuals’ medical records and chest radiographs. The diagnosis of silicosis was based on cr...

The southernmost part of Thailand is a unique and culturally diverse region that has been greatly affected by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak during the coronavirus disease-2019 pandemic. To gain insights into this situation, we analyzed 1942 whole-genome sequences of SARS-CoV-2 obtained from the five south...

Background Due to limited numbers of palliative care specialists and/or resources, accessing palliative care remains limited in many low and middle-income countries. Data science methods, such as rule-based algorithms and text mining, have potential to improve palliative care by facilitating analysis of electronic healthcare records. This study aim...

Introduction This study aimed to investigate factors associated with time-to-referral due to worsening symptoms in patients with laboratory-confirmed COVID-19 in southern Thailand. While underlying diseases have been evaluated to assess COVID-19 severity, the influence of vaccinations and treatments is also crucial. Methods A cohort of 8,638 patie...

Objective: We developed a simple nutritional counseling tool for adults with liver cirrhosis, aiming for doctors, nurses, and patients as the tool’s primary users.Material and Methods: The tool was created in a booklet design and based on the European Society of Parenteral and Enteral Nutrition guideline, which comprises four parts, knowledge about...

Background We aimed to investigate the incidence, fatality, and associated factors in patients with hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) hospitalized for coronavirus disease 2019 (COVID-19) infection and reimbursed from the National Health Security Office (NHSO). Methods The retrospective cohort analysis was...

Increasing air pollution and decreasing exposure to greenness may contribute to the metabolic syndrome (MetS). We examined associations between long-term exposure to residential greenness and air pollution and MetS incidence in the Bangkok Metropolitan Region, Thailand. Data from 1369 employees (aged 52–71 years) from the Electricity Generating Aut...

Atmospheric particulate matter smaller than 2.5 micron (PM2.5) was evaluated at four sites in the lower southern part of Thailand during 2019–2020 to understand the impact of PM2.5 transport from peatland fires in Indonesia on air quality during the southwest monsoon season. Mass concentration and chemical bound-PM, including carbon composition, e....

Introduction: Hepatic artery occlusion (HAO) is a significant complication post-liver transplantation. Doppler ultrasound (DUS) has been widely used as an initial screening test for detecting HAO; however, its performance is often not sufficient. Although other diagnostic tests such as computed tomography angiography (CTA), magnetic resonance angi...

In May 2021, there was a COVID-19 outbreak on board a construction support ship traveling from India to Thailand. Controlling the outbreak on this offshore vessel from 11 May to 2 June 2021 was applied. This case report describes the teamwork management of COVID-19 control on the vessel in the Gulf of Thailand. We summarized the COVID-19 outbreak c...

Diabetes mellitus is widely thought to be a risk factors of cancers, but evidence of the association remains inconclusive, especially in Asian countries where few relevant studies have been conducted. Our study aimed to estimate overall and specific types of cancer risks among diabetes patients in Southern Thailand. Patients diagnosed with diabetes...

Introduction Pain is a major symptom in cancer patients. World Health Organization recommends opioids as the main analgesic agent. Few studies have examined the amount of opioid uses in cancer patients in Southeast Asia, however, none of them have examined the factors associated with the amount of opioid uses which were lower than required. Object...

Acid–base disorders occur when the body’s normal pH is out of balance. They can be caused by problems with kidney or respiratory function or by an excess of acids or bases that the body cannot properly eliminate. Acid–base and potassium imbalances are mechanistically linked because acid–base imbalances can alter the transport of potassium. Both aci...

Background: Digital mammography is the most efficient screening and diagnostic modality for breast cancer (BC). However, the technology is not widely available in rural areas. This study aimed to construct a prediction model for BC in women scheduled for their first mammography at a breast center to prioritize patients on waiting lists. Methods:...

Higher residential greenness is associated with a lower risk of chronic kidney disease, but evidence on the association between greenness exposure and kidney function has not been conducted. Using cohort data from Electricity Generating Authority of Thailand (EGAT) employees, we investigated the association between long-term exposure to greenness a...

Background: Hepatitis E virus (HEV), the causative agent of hepatitis E, is a common but self-limiting disease. However, in immunosuppressed kidney transplant 47 recipients (KTRs), HEV infection can become chronic. We investigated risk factors associated with HEV infection among 271 KTRs at the Johns Hopkins Hospital transplanted between 1988 and...

Exposure to polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs) in crude oil has carcinogenic effects on various organ systems. This longitudinal cohort study examined the effects of oil spill exposure on the haematological, hepatic, and renal profiles of Rayong oil spill clean-up workers. The sample included 869 clean-up...

Exposure to particulate air pollution may induce hepatotoxic effects via low-grade inflammation. However, only a few longitudinal epidemiological studies have investigated the long-term effects of air pollution on liver enzyme levels. The present study examined associations between long-term air pollution exposure and serum liver enzymes [alkaline...

Atmospheric particulate matter smaller than 2.5 micron (PM 2.5 ) was evaluated at four sites in the lower southern part of Thailand during 2019-2020. Mass concentration and chemical bound-PM, including carbon composition e.g. organic carbon (OC) and elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and inorganic elements, were analyze...

Over time, large amounts of clinical data have accumulated in electronic health records (EHRs), making it difficult for healthcare professionals to navigate and make patient-centered decisions. This underscores the need for healthcare recommendation systems that help medical professionals make faster and more accurate decisions. This study addresse...

Applying health measures to prevent COVID-19 transmission caused disruption of businesses. A practical plan to balance public health and business sustainability during the pandemic was needed. Herein, we describe a “Bubble and Seal” (B&S) program implemented in a frozen seafood factory in southern Thailand. We enrolled 1539 workers who lived in the...

BACKGROUND The COVID-19 pandemic severely affected global health. In May 2021, there was a COVID-19 outbreak on board a ship in Songkhla Province, Thailand. Isolation and quarantine were conducted as the vessel was highly favorable for contracting and spreading infectious diseases because of environmental contamination and sharing of facilities. O...

Objective: To investigate the reasons leading cancer patients to visit an emergency room (ER) and the associated factors, which will suggest policies to reduce unnecessary ER visits.Material and Methods: A cross-sectional study was done in Songklanagarind Hospital, the major referral center in Southern Thailand. The data of cancer patients aged 18...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Two doses of an inactivated SARS-CoV-2 vaccine (CoronaVac) have been shown to be insufficient to protect against variants of concern (VOCs), while viral vector vaccines remain protective against the infection. Herein, we conducted a preliminary study to evalu...

p>Tuberculosis (TB) is still a serious public health concern across the world, causing 1.4 million deaths each year. However, there has been a scarcity of radiological interpretation skills in many TB-infected locations, which may cause poor diagnosis rates and poor patient outcomes. A cost-effective and efficient automated technique might help scr...

p>Tuberculosis (TB) is still a serious public health concern across the world, causing 1.4 million deaths each year. However, there has been a scarcity of radiological interpretation skills in many TB-infected locations, which may cause poor diagnosis rates and poor patient outcomes. A cost-effective and efficient automated technique might help scr...

Nanopollutants are nanoparticles that have escaped into the environment and can include engineered nanoparticles as well as nanoparticles that are products of degradation (e.g. nanoplastics) or other processes. As many of these particles are only recently developed or described there is still a lot to learn about where they come from, where they en...

Purpose: To determine accuracy and relative risk (RR) of posttreatment optical coherence tomography (OCT) features in identifying complete or incomplete polypoidal regression in polypoidal choroidal vasculopathy (PCV). Design: Validity analysis. Methods: Treatment-naive PCV eyes undergoing OCT and indocyanine green angiography (ICGA) at baseli...

Preterm infants are prone to growth and developmental delay, especially social-emotional development. Sensory stimulation may benefit developmental outcomes for these vulnerable infants. This study aims to determine whether 5-integrated sensory stimulation (5-ISS) improves preterm infant social-emotional development. A randomized, parallel trial wa...

Allergic reactions to medication range from mild to severe or even life-threatening. Proper documentation of patient allergy information is critical for safe prescription, avoiding drug interactions, and reducing healthcare costs. Allergy information is regularly obtained during the medical interview, but is often poorly documented in electronic he...

Purpose : To determine prevalence of probable polypoidal choroidal vasculopathy (PCV) among White patients with neovascular age-related macular degeneration (nAMD) using non-ICGA criteria Design : Multicenter, multinational retrospective cross-sectional study Methods : 208 treatment naïve eyes from Hispanic and non-Hispanic White individuals diag...

A veterinarian in Thailand was diagnosed with COVID-19 after being sneezed on by an infected cat owned by an infected patient. Genetic study supported the hypothesis of SARS-CoV-2 transmission from the owner to the cat, and then from the cat to the veterinarian.

Objectives The study aimed to examine the association between individual and community levels in relation to subjective well-being (SWB) among the migrant and local elderly. It particularly focuses on the extent to which and the ways in which the residential environment of migrant and local elderly influences their SWB. Design A cross-sectional st...

Background Haemodialysis (HD) transfer (HDT) is the major challenge of peritoneal dialysis (PD). This study aimed to analyse the time-dependent incidence rates and risk factors for permanent HDT in patients under Thailand’s PD First policy. Methods The records of 20,545 patients from January 2008 to June 2018 were studied. The time on therapy (TOT...

Purpose The Rayong oil spill incident of 2013 leaked over 50,000 barrels of crude oil into the Gulf of Thailand. This study assessed trends and changes in the haematological, renal, and hepatic indices among the Rayong oil spill clean-up workers 5 years after the spill. Methods Haematological, renal, and hepatic indices measured for 570 oil spill...

We conducted a community-based survey to compare the subjective well-being (SWB) and quality of life (QoL) of 470 rural-to-urban migrant and 422 local older adults living in Dongguan, China. Ordinal logistic regression was used to assess the dose-response relationships of SWB, QoL, and individual and environmental factors. Results show that migrant...

Background Hepatitis E virus (HEV) infection has been associated with immune-mediated kidney diseases in developing countries. However, its relationship with kidney transplant outcomes has never been studied. We investigated the association between HEV infection and kidney graft rejection among kidney transplant recipients (KTRs). Methods We condu...

Critical care staff are presented with a large amount of data, which made it difficult to systematically evaluate. Early detection of patients whose condition is deteriorating could reduce mortality, improve treatment outcomes, and allow a better use of healthcare resources. In this study, we propose a data-driven framework for predicting the risk...

The objective of this study was to investigate the seasonal patterns and trends of air pollutants in upper northern Thailand (UNT) from 2004 to 2018. The hourly air pollutant concentration data recorded from 6 monitoring stations in the UNT were obtained from the Pollution Control Department, Ministry of Natural Resources and Environment of Thailan...

Background Kidney dysfunction is considered a cardiovascular risk factor. However, few longitudinal studies have examined the effects of air pollution on kidney function. We evaluated associations between long-term air pollution exposure and estimated glomerular filtration rate (eGFR) using data from a cohort of the Electricity Generating Authority...

It has been reported that long-term exposure to air pollution is linked to metabolic syndrome (MetS), which is an important risk factor for cardiovascular diseases. However, no study has investigated the epidemiological association between long-term air pollution exposure and MetS in Southeast Asia. We examined the association between long-term exp...

Objective: To investigate the demographic characteristics, seasonal variations, effects associated with air pollution, and geographic morbidity of asthma in Songkhla. Material and Methods: This research conducted a time series analysis of secondary data from 1 January, 2013 to 31 December, 2017. The distributed lag non-linear model was employed to...

Background Ankle-brachial index (ABI) and cardio-ankle vascular index (CAVI) are surrogate measures of atherosclerosis based on the functional performance of vessels, and are highly related to cardiovascular events. However, only a few longitudinal studies have been conducted on their associations with long-term air pollution exposure. Objective T...

Only a few studies have investigated the association between long-term exposure to air pollution and alterations of serum lipids and blood sugar level in developing countries. The present longitudinal study examined associations between long-term air pollution exposure and serum lipids [total cholesterol (TC), triglycerides (TG), high-density lipop...

Background Spontaneous bacterial peritonitis (SBP) is a bacterial infection associated with a high mortality rate in cirrhotic patients. The gold standard for the detection of SBP is a manual cell count from ascitic fluid, however, alternative screening methods are under investigation. In particular, leukocyte esterase reagent strips (LERS) has bee...

Objective: To estimate the prevalence of patients requiring palliative care in outpatient clinics and associated factors.Materials and Methods: A cross-sectional study was conducted by retrospectively reviewing the electronic medical records of cancer patients visiting the outpatient clinics in the major tertiary care institution in southern Thaila...

Background: Previous studies have shown a relationship between renin angiotensin aldosterone system (RAAS) and insulin resistance. This in turn can delay the onset of diabetes mellitus (DM). The impact of angiotensin receptor blocker (ARB) on the fasting plasma glucose (FPG) level is not clear. Objective: To compare the overtime FPG between ARB and...

Purpose To understand timing of complete polypoidal regression on indocyanine green angiography (ICGA) after aflibercept injections in polypoidal choroidal vasculopathy (PCV). Design Multicenter prospective study Participants Adults with treatment-naïve PCV Methods After IRB approval, participants were enrolled and followed for 1 year, Apr 1, 20...

Objectives: Ascites is a pathologic buildup of fluid in the peritoneal cavity. Knowledge is lacking in clinical outcome in pediatric patients with ascites. We aim to identify and assess clinical variables to associated with morbidity and mortality in pediatric patients hospitalized with ascites. Methods: A retrospective cohort study was performe...

Background Identification of patients who might benefit from palliative care among countries with different socioeconomic and medical contexts is challenging. The Supportive and Palliative Care Indicators Tool for a Low-income Setting (SPICT-LIS) was designed to help physicians identify patients in low-income setting who might benefit from palliati...

Backgrounds: The main objective of this study was to compare the pain control efficacy of local administration of Lidocaine with or without the nonsteroidal anti-inflammatory drug, Ketorolac, and local conventional Lidocaine injection in core needle biopsy of the musculoskeletal tumor. Methods: The current study was a randomized, double-blind co...

Background: Spontaneous bacterial peritonitis (SBP) is a common bacterial infection in cirrhotic patients associated with a high mortality rate. Prompt diagnosis and early antibiotic administration are crucial in minimizing adverse outcomes. Although detection of ≥250 polymorphonuclear leukocytes (PMN) in ascitic fluid is the current gold standard...

บทคัดย่อ ความขัดแย้งในพื้นที่จังหวัดชายแดนใต้เป็นปัญหาที่รุนแรงและเกิดขึ้นต่อเนื่องมาจนถึงปัจจุบัน การศึกษานี้มีวัตถุประสงค์สำคัญ 2 ประการคือ หนึ่ง เพื่อสร้างดัชนีวัดความรุนแรงของความขัดแย้ง และสอง เพื่อประเมินผลกระทบทางเศรษฐกิจจากสถานการณ์ความขัดแย้งที่เกิดขึ้น การศึกษานี้ได้จัดทำดัชนีความรุนแรงของความขัดแย้งในพื้นที่ชายแดนใต้ (Deep South Violence...

Hepatitis E is considered rare in the United States (US) despite its widespread occurrence in Asian and African countries. The objective of this study was to describe the characteristics of hepatitis E‐related pregnancies and acute‐on‐chronic liver failure and analyze trends for hepatitis E diagnosis among hospitalized patients in the US.We examine...

Given that social environmental factors have hardly been considered in studies exploring the subjective well-being of internal migrants aged 60 years and older in China, we aimed to investigate the effects of social environmental factors on the subjective well-being of 470 internal migrants aged from 60 to 87 years using data collected from a surve...

Background: In July of 2013, a pipeline connecting an offshore oil platform to a tanker caused crude oil to spill into the Sea of Rayong off the coast of Thailand. The resulting oil slick, estimated to be between 50 and 190 cubic meters (336-1,200 barrels), washed ashore one day later on the island of Samet. We conducted a study to quantify intern...

Background Several studies have shown the health effects of air pollutants, especially in China, North American and Western European countries. But longitudinal cohort studies focused on health effects of long-term air pollution exposure are still limited in Southeast Asian countries where sources of air pollution, weather conditions, and demograph...

Background Abdominal paracentesis is performed as a diagnostic test in children with ascites. Serum albumin to ascitic fluid albumin gradient (SAAG) is frequently used in adults to distinguish types of portal hypertension. We aim to investigate the utilization of SAAG and other biomarkers in determining the etiology of significant ascites in childr...

Background Evaluation of pulmonary arterial pressure is crucial among cirrhotic patients considering moderate portopulmonary hypertension (POPH) is a contraindication for liver transplant. Although right heart catheterization (RHC) is the most accurate method to diagnose POPH, it is invasive. Objective Aim is to evaluate the performance of echocar...

Objective: To compare the incidence along with risk factors of vascular complications between patients having undergone Coronary angiography/Percutaneous Coronary Interventions (CAG/PCIs); as day cases and those as inpatients. Material and Methods: Our study is a retrospective cohort study. We performed a retrospective chart review of the patients...

Background & Aims A practical, inexpensive, and non-invasive biomarker of liver fibrosis is needed as a reliable screening test for cystic fibrosis-associated liver disease (CFLD). Studies have shown the utility of AST to Platelet Ratio Index (APRI), fibrosis index based on 4 factors (FIB-4), and gamma-glutamyl transferase (GGT) as good biomarkers...

Objective: To measure the Quality of Life (QoL) and Caregiver Burden Scale (CBS) of lung cancer patients’ caregivers and assess the associated factors. Material and Methods: This was a cross-sectional study. We interviewed lung cancer patients and their caregivers who were visiting the outpatient department of a tertiary hospital in Thailand. QoL...

Background En-bloc resection of giant cell tumors (GCTs) of the distal radius remains the mainstay treatment for those with high-graded lesions. Several techniques have been described for reconstruction of the resected segment, of which transposition of the ipsilateral ulna is scarcely reported. Objectives To investigate the efficacy and safety of...

Chinese economic development has led to a significant rise in internal migration over the last 20 years, including large numbers of elderly. When elderly Chinese people migrate, they still register their residency to their place of origin and often do not register with the new administrative office at the destination due to the household registrati...

Background: Intraoperative leak test (IOLT) is commonly performed to evaluate the integrity of an anastomosis or staple line during bariatric surgery. However, the utility of IOLT is controversial. Objective: To evaluate the effect of IOLTon postoperative leak-related outcomes after primary bariatric surgery. Setting: Metabolic and Bariatric Surger...

Purpose: Although ultrasound has been widely used to evaluate transjugular intrahepatic portosystemic shunts (TIPS) patency, several studies have reported conflicting data regarding its performance. Therefore, we aimed to evaluate performance of ultrasound for detection of TIPS dysfunction by performing a meta-analysis. Methods: Literature searc...

Background: Intraoperative leak test (IOLT) is commonly performed to evaluate the integrity of an anastomosis or staple line during bariatric surgery. However, the utility of IOLT is controversial. Objective: To evaluate the effect of IOLT on postoperative leak-related outcomes after primary bariatric surgery. Setting: Metabolic and Bariatric...

Importance The use of indocyanine green angiography (ICGA) is a criterion standard for diagnosing polypoidal choroidal vasculopathy (PCV), an endemic and common cause of vision loss in Asian and African individuals that also presents in white individuals. However, the use of ICGA is expensive, invasive, and not always available at clinical centers....

Background Sepsis is a major public health concern. Revised definitions of sepsis in 2016 from the systemic inflammatory response syndrome (SIRS) criteria to the Sequential Organ Failure Assessment (SOFA) score made change in the sepsis case detection. One-hour bundle proposed by the Surviving Sepsis Campaign Bundle 2018 made the process more pract...

Background VRE and CRE are emerging pathogens among Multidrug-resistant Organisms (MDROs) which can lead to morbidity, mortality and high hospital costs. Several studies showed differences in benefits and effectiveness of control strategies among organisms. Implementation of these strategies in resource-limited settings is challenging. Methods A V...

Background There is increasing evidence of non‐invasive measurement using elastography such liver stiffness (LS), spleen stiffness (SS), and LS‐spleen diameter to platelet ratio score (LSPS) for detection of esophageal varices (EV); however, data regarding comparison between these three parameters are limited. Methods We performed a systemic revie...