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Publications
Publications (139)
Muscle injuries are the leading cause of sports casualties. Because of its high plasticity, skeletal muscle can respond to different stimuli to maintain and improve functionality. Intermittent hypobaric hypoxia (IHH) improves muscle oxygen delivery and utilization. Hypobaria coexists with cold in the biosphere, opening the possibility to consider t...
Chlorella is a marine microalga rich in proteins and containing all the essential amino acids. Chlorella also contains fiber and other polysaccharides, as well as polyunsaturated fatty acids such as linoleic acid and alpha-linolenic acid. The proportion of the different macronutrients in Chlorella can be modulated by altering the conditions in whic...
La formación en docencia y la adquisición de competencias docentes son elementos primordiales en el desarrollo profesional de cualquier profesor y, por supuesto, del profesorado novel. La Universidad de Barcelona (UB) es la única universidad española que ofrece un máster destinado a la formación de su profesorado novel, por lo que puede considerars...
It is usual in anatomical and physiological research to assess the effects of some intervention on extremities (e.g., training programmes or injury recovery protocols) using one muscle for the intervention and its contralateral as control. However, the existence of laterality (left‐handedness or right‐handedness) in athletes of different specialiti...
(1) Background: half-marathon races are popular among recreational runners, with increases in participation among middle-aged and women. We aimed to determine the effects of two half-marathon training programs on hematological and biochemical markers in middle-aged female recreational runners; (2) Methods: ten women (40 ± 7 years) followed moderate...
The benefits of intermittent hypobaric hypoxia (IHH) exposure for health and its potential use as a training tool are well-documented. However, since hypobaric hypoxia and cold are environmental factors always strongly associated in the biosphere, additive or synergistic adaptations could have evolved in animals’ genomes. For that reason, the aim o...
Marine and freshwater algae and their products are in growing demand worldwide because of their nutritional and functional properties. Microalgae (unicellular algae) will constitute one of the major foods of the future for nutritional and environmental reasons. They are sources of high-quality protein and bioactive molecules with potential applicat...
This study examines the influence of intermittent exposure to cold, hypobaric hypoxia, and their combination, in gut microbiota and their metabolites in vivo, and explores their effects on the physiology of the host. Sprague-Dawley rats were exposed to cold (4°C), hypobaric hypoxia (462 torr), or both simultaneously, 4 h/day for 21 days. Biometrica...
A crucial subject in sports is identifying the inter-individual variation in response to training, which would allow creating individualized pre-training schedules, improving runner’s performance. We aimed to analyze heterogeneity in individual responses to two half-marathon training programs differing in running volume and intensity in middle-aged...
Purpose: To test the effectiveness on recreational female middle-aged runners of a programme of high-intensity interval training (HIIT) for a half-marathon race contrasted to a conventional moderate-intensity continuous training (MICT).
Methods: Twenty recreational female runners (40 ± 7 years) followed MICT or HIIT schedules for training a half-ma...
This study used time to exhaustion (TTE) to predict V̇O2max in female recreational master runners. Forty-two middle-aged women (mean = 40.5 ± 5.9 years) who had trained for recreational running performed two Université de Montréal Track Tests in the facilities of the University of Barcelona (Spain). The first was performed on a treadmill (t), the s...
El presente trabajo muestra el estudio descriptivo sobre las necesidades formativas percibidas por el personal docente e investigador (PDI) de la Universidad de Barcelona (UB), realizado por el Instituto de Desarrollo Profesional (IDP-ICE) de dicha universidad. Para obtener los datos ello se ha utilizado un cuestionario que recoge la opinión del PD...
In this study, we propose a novel three-criteria performance score to semiquantitatively classify the running style, the degree of involvement and compliance and the validity of electric shock count for rats exercising on a treadmill. Each score criterion has several style-marks that are based on the observational registry of male Sprague-Dawley ra...
In recent years, the altitude acclimatization responses elicited by short-term intermittent exposure to hypoxia have been subject to renewed attention. The main goal of short-term intermittent hypobaric hypoxia exposure programs was originally to improve the aerobic capacity of athletes or to accelerate the altitude acclimatization response in alpi...
We used an animal model to elucidate the effects of an intermittent hypobaric hypoxia (IHH) and endurance exercise training (EET) protocol on bodyweight (BW), food and water intake, and oxygen consumption. Twenty-eight young adult male rats were divided into four groups: normoxic sedentary (NS), normoxic exercised (NE), hypoxic sedentary (HS), and...
Altitude training has become increasingly popular in recent decades. Its central and peripheral effects are well-described; however, few studies have analyzed the effects of intermittent hypobaric hypoxia (IHH) alone on skeletal muscle morphofunctionality. Here, we studied the effects of IHH on different myofiber morphofunctional parameters, invest...
The revision and evaluation of the teaching practice is a demand of the society that every time demands a better formation of competent professionals in its area. An essential edge in the training process, which must be constant, is the reflection about the task that the educator performs directly and what the skills and abilities that he/she is or...
Unaccustomed eccentric contractions induce muscle damage, calcium homeostasis disruption, and mitochondrial alterations. Since exercise and hypoxia are known to modulate mitochondrial function, we aimed to analyze the effects on eccentric exercise-induced muscle damage (EEIMD) in trained rats using 2 recovery protocols based on: (i) intermittent hy...
This study analyses the effect that the training programs of the Institute of Education (ICE) of the University of Barcelona (UB) has on the teaching of the trainees who received this training. The satisfaction of the teaching staff about the courses, the level of transfer of the knowledge acquired to their teaching and its impact on the academic p...
The increase in pulmonary arterial pressure (PAP) due to hypoxic pulmonary vasoconstriction (HPV) could be a limiting factor for physical performance during hypoxic exposure. Sildenafil has been shown to reduce PAP in situations of moderate or severe hypoxia, and consequently its role as an ergogenic aid and even a possible doping substance must be...
En este trabajo valoramos la competencia de innovación docente del profesorado universitario como medio para mejorar la calidad de la docencia y conseguir un mejor aprendizaje de los estudiantes. Esta competencia es una de las seis definidas como relevantes, y considerada como una competencia significativa por el Grupo Interuniversitario de Formaci...
This study compared subjective effort perception with objective physiological measures during high-intensive intermittent exercise performed in normoxia, moderate hypoxia (FiO2: 16.5%) and severe hypoxia (FiO2: 13.5%). Sixteen physically active subjects performed an equal training session on three different days. Training consisted of 6 "all-out" s...
Existing evidence suggests that body balance ability is associated with dental occlusion. The purpose of this study was to determine whether: (i) there are differences in balance between opposed dental occlusion (intercuspal position, ICP; cotton rolls, CR) for two extreme levels of stability and (ii) the influence of dental occlusion on the balanc...
Sildenafil has proven to efficiently reduce the increase in pulmonary artery pressure provoked by hypoxic pulmonary vasoconstriction. However, its role as a possible factor in increasing exercise performance under hypoxic conditions remains to be demonstrated. The use of sildenafil has increased among mountaineers, not as a high altitude pulmonary...
The possible effects of blue light during acute hypoxia and the circadian rhythm on several physiological and cognitive parameters were studied.
Fifty-seven volunteers were randomly assigned to 2 groups: nocturnal (2200-0230 hours) or diurnal (0900-1330 hours) and exposed to acute hypoxia (4000 m simulated altitude) in a hypobaric chamber. The part...
Objective: Training high-living low model has been studied as an intermittent hypoxic training (IHT) for anaerobic performance improvement. To test the hypothesis that a high-intensity circuit strength training (CST) performed in hypoxia increases the anaerobic running performance at sea level. Equipment and methods: Twelve sub-elite male 400-m run...
Unaccustomed eccentric exercise is a well-documented cause of exercise-induced muscle damage. However, in trained subjects muscle injury involves only light or moderate tissue damage. Since trained rats are widely used as a model for skeletal muscle injury, here we propose a semiquantitative scoring tool to evaluate muscle damage in trained rats. T...
p>En este trabajo se presenta la perspectiva que tienen los estudiantes, sobre las competencias del buen docente universitario, a partir de un cuestionario diseñado en base a las competencias docentes definidas y validadas en el marco del proyecto REDU2012”. Han respondido al cuestionario 10302 estudiantes de grado y 1700 de máster de 15 universida...
En este trabajo se presenta la perspectiva que tienen los estudiantes, sobre las competencias del buen docente universitario, a partir de un cuestionario diseñado en base a las competencias docentes definidas y validadas en el marco del proyecto REDU2012”. Han respondido al cuestionario 10302 estudiantes de grado y 1700 de máster de 15 universidade...
Reflecting on one's teaching practices and assessing and analyzing the results of one's teaching are the skills developed on the Master's course in university teaching for novice teachers at the University of Barcelona. First, novice teachers are assigned a mentor; then, their progress is assessed by a new figure, a senior lecturer (monitor), who i...
Studies are needed to understand the role of CD34 expressing cells with regard to efficient engraftment, especially in the adjuvant treatment of cancer.
In this study we have used a modified method in our laboratory for routinely counting CD34+ cells. Unlysed whole blood samples were stained with the DNA-selective and cell membrane-permeant Vibrant...
The success in weaning process demand a good balance between cardiac and respiratory system. Heart-rate variability (HRV), a new non invasive tool to characterize autonomic function and cardiorespiratory interaction, may be useful to assess patient capability during weaning process.
Contradictory results are still reported on the influence of dental occlusion on the balance control. We attempted to determine whether there are differences in balance between opposed dental occlusion (Intercuspal position (ICP)/"Cotton rolls" mandibular position (CR)) for two extreme levels of stability (stable/unstable). Twenty-five subjects wer...
Our goal was to address if intermittent hypobaric hypoxia (IHH) exposure can help to increase the number of peripheral blood circulating progenitor cells and side population (SP) stem cells, in order to establish the usefulness of this intervention for skeletal muscle repair, because these cells play a role in tissue regeneration. Male Sprague-Dawl...
Objectives: The purpose of the present study was to determine if high intensity exercise performed in hypoxia could affect the salivary pH response in comparison to normoxia.
Methods: Eight healthy and physically active subjects performed a randomized single blinded protocol consisting in six sets of fifteen seconds stretch-shortening-cycles (SSC)...
Objectif
Cette étude avait pour objectif à évaluer la capacité anaérobie après un protocole d’entraînement d’endurance de puissance (EST) pendant 4 semaines.
Méthodes
Un groupe de volontaires (n = 5) a été entraîné dans un caisson hypobare à une altitude simulée de 2500 m (HYP), tandis que l’autre (n = 7), l’a été au niveau de la mer (NOR). La pui...
Intermittent hypobaric hypoxia (IHH) exposure, accompanied or not with active recovery, can help to skeletal muscle repair. However, the erythropoietic response elicited can disturb blood rheology and thus alter the oxygen delivery to tissues. Male Sprague-Dawley rats were studied in two basal states: untrained and trained and compared with early (...
The DyeCycle Violet stain is selectively retained by CD34+ cells, which allows us to use peripheral blood without lysis; improving the accuracy in the measurements of the samples. These data demonstrate that day 7 is the day that reflected the greatest increase in number of CD34+ labelled stem cells, both in the HYP and EHYP groups, which agrees wi...
Introducción: Valores bajos del pH salival están fuertemente relacionados con un mayor riesgo de caries dental. El objetivo del presente estudio fue valorar los cambios en los valores del pH salival tras la realización de ejercicio anaeróbico máximo, su posible relación con el valor de lactato sanguíneo, y el análisis del estado de la cavidad bucal...
p>El Grupo Interuniversitario de Formación Docente (GIFD) está formado por las unidades y centros de formación (ICE-UB, IDES-UAB, ICE-UPC, CQUID-UPF, ICE-UdG, ICE-UdL, ICE-URV y eLC-UOC) de las ocho universidades públicas catalanas. Estas unidades actualmente se encuentran en un proceso de reformulación de las actividades y planes de formación que...
Introduction
A low salivary pH is strongly associated with the incidence of dental caries. The aim of this study was to determine if high intensity anaerobic exercise could affect the salivary pH response, and to determine if there is correlation between salivary pH and blood lactate values. Additionally, we also aim to determine the state of oral...
Not one, but two sessions of a downhill exercise until exhaustion, proved sufficient to cause muscle injury to the majority of the rats. Although the training period is relatively long in comparison with other existing methods the simulation is more relevant to mimic trained athletes, since the injury was associated with a natural locomotion on wel...
This article present the project developed in 2011 by units and training centers from all public
universities in Catalonia. The project is devised towards the quality improvement of the higher
education system and of the activity undertaken by the faculty at the university. In order to achieve
these objectives, it focuses on the identification of t...
Este artículo presenta el proyecto desarrollado durante el año 2011 por las unidades y centros de
formación de las universidades públicas catalanas. El proyecto se orienta a la mejora de la calidad del
sistema de educación superior y de la actividad del profesorado universitario mediante planes de
formación específicamente diseñados con esta finali...
Peripheral blood is an easily accessed source for stem cell production; however, the number of cells produced is relatively low. We hypothesized that ischemic preconditioning may serve as a safe method to increase the number of CD34+ cells that can be harvested and cultured in a short period. This study was conducted to test this hypothesis by exam...
Seven healthy young men were submitted twice to a hypoxia tolerance test at a simu-lated altitude (3000 m). Their first acute exposure was in a hypobaric chamber; and the second, in a hypoxic tent. Cardiorespiratory parameters and heart rate variability measurements were obtained under each hypoxic condition. A significant decrease of 6% to 8% comp...
Objective: To determine whether twelve sessions of resistance training on lower limbs at sim-ulated altitude (2500 m) were efficient to elicit an improvement in heart rate recovery index in the first 3 min of recovery after a maximal jump test. Materials and methods: Twelve young physically active subjects were divided in two balanced groups for tr...
The aim of this study was to test the hypothesis that administration of low-flow oxygen will improve physical performance in subjects unacclimatized to altitude. We evaluated the effects of oxygen supplementation on functional capacity and acute mountain sickness (AMS) symptoms in young, healthy male and female subjects who performed a 2-km fast wa...
Programs of intermittent hypobaric hypoxia (IHH) exposure are used to raise hemoglobin concentration and erythrocyte mass. Although acclimation response increases blood oxygen transport capacity leading to a VO(2max) increase, the effects of reactive oxygen species (ROS) might determine the behavior of erythrocytes and plasma, thus causing a worse...
La implantació dels nous graus com a desenvolupament de les directrius de l’EEES plantegen tot un seguit de reptes per a la comunitat docent en general, i per a la nostra universitat en particular. En aquest article es presenta el marc d’actuacions portades a terme des del principi del 2010 pels responsables de desenvolupar les estratègies de supor...
Our goal was to determine whether short-term intermittent hypoxia exposure, at a level well tolerated by healthy humans and previously shown by our group to increase EPO and erythropoiesis, could mobilize hematopoietic stem cells (HSC) and increase their presence in peripheral circulation.
Four healthy male subjects were subjected to three differen...
GV and CJ during HME protocol. The intensity of muscle electrostimulation can be observed in this short movie.
CHEx-1 Hypobaric chamber. The hypobaric chamber into BioPol facility at University of Barcelona Campus Bellvitge.
Intermittent hypobaric hypoxia (IHH) exposure induces a rise in hemoglobin concentration and an increase in erythrocyte mass in both rats and humans. Although this response increases blood oxygen transport capacity, paradoxically, it could impair blood flow and gas exchange because of the blood viscosity alterations associated with the rising hemat...
We studied the effect of intermittent hypobaric hypoxia exposure on lactate dehydrogenase and citrate synthase activities, together with myoglobin content, of rat myocardium, tibialis anterior, and diaphragm muscles. The intermittent hypoxia exposure programme consisted of daily 4-h sessions in a hypobaric chamber (5000 m) over a period of 22 days....
Viscor, Gines Javierre, Casimiro Pages, Teresa Ventura, Josep-Lluis Ricart, Antoni Martin-Henao, Gregorio Azqueta, Carmen Segura, Ramon
Diseño: Rosa Marín Ribas La radiotelemetría permite el registro de variables fisiológicas de animales conscientes y con libertad de movimientos, sin provocar artefactos debidos al estrés y en un ambiente libre de la influencia del investigador, y por tanto, eliminando sus consecuencias en el experimento. Esta técnica resulta especialmente útil en e...
Producción y edición: Rosa Marín Ribas La radiotelemetría permite el registro de variables fisiológicas de animales conscientes y con libertad de movimientos, sin provocar artefactos debidos al estrés y en un ambiente libre de la influencia del investigador, y por tanto, eliminando sus consecuencias en el experimento. Esta técnica resulta especialm...
Producción y edición: Rosa Marín Ribas La radiotelemetría permite el registro de variables fisiológicas de animales conscientes y con libertad de movimientos, sin provocar artefactos debidos al estrés y en un ambiente libre de la influencia del investigador, y por tanto, eliminando sus consecuencias en el experimento. Esta técnica resulta especialm...
The difference between genders has generated increasing interest in recent years. It is well known that women and men show differences in their respiratory system: different red blood cell counts, haemoglobin and 2,3-diphosphoglycerate plasma concentrations. Recently, further differences have been found in the ventilatory response to hypoxia and ex...
Adult male Sprague-Dawley rats were randomly assigned to two groups: control and anaemic. Anaemia was induced by periodical blood withdrawal. Extensor digitorum longus and soleus muscles were excised under pentobarbital sodium total anaesthesia and processed for transmission electron microscopy, histochemical and biochemical analyses. Mitochondrial...
Three groups of sedentary male rats were exposed to intermittent hypobaric hypoxia (IHH) for 22 days (4 h/day, 5 days/week) in a hypobaric chamber at a simulated altitude of 5,000 m. Tibialis anterior (TA) and diaphragm (DG) were removed at the end of the programme (H group), and 20 or 40 days later (P20 and P40 groups). A control group (C) was mai...
As in humans, the haemoglobin concentration rise and erythrocyte mass increase are the most significant of the haematological adaptive changes induced by intermittent hypobaric hypoxia exposure (IHHE) in rats. Although this response is oriented to increase oxygen transport capacity, paradoxically, the increasing blood capacity could impair peripher...