Teresa F Fernandes

Teresa F Fernandes
Heriot-Watt University · Energy, Geoscience, Infrastructure and Society

Professor, Environmental Engineer, MSc Marine and Fisheries Science, PhD Zoology, PgDip Applied Statistics

About

173
Publications
53,644
Reads
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10,955
Citations
Citations since 2016
47 Research Items
5777 Citations
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
Additional affiliations
February 2011 - present
Heriot-Watt University
Position
  • Professor
Education
October 1987 - December 1992
University of Aberdeen
Field of study
  • Zoology, Environmental Science

Publications

Publications (173)
Article
Full-text available
Due to the unique characteristics of nanomaterials (NM) there has been an increase in their use in nanomedicines and innovative medical devices (MD). Although large numbers of NMs have now been developed, comprehensive safety investigations are still lacking. Current gaps in understanding the potential mechanisms of NM-induced toxicity can make it...
Article
Full-text available
Background The EU-project GRACIOUS developed an Integrated Approach to Testing and Assessment (IATA) to support grouping high aspect ratio nanomaterials (HARNs) presenting a similar inhalation hazard. Application of grouping reduces the need to assess toxicity on a case-by-case basis and supports read-across of hazard data from substances that have...
Chapter
The increasing application and use of TiO 2 nanoparticles (NPs) ha ve led to higher production and subsequent release of these particles into the aquatic environment. Substances in surface waters will sorb to TiO 2 NPs, and sorption has implications on the fate, transport, and environmental consequences of both the substance and the NPs. In this ch...
Article
Full-text available
Marine mammals are vulnerable to a variety of acute and chronic anthropogenic stressors, potentially experiencing these in isolation, successively and/or simultaneously. Formal assessment of the likely impact(s) of the cumulative effects of multiple stressors on a defined population is carried out through a Cumulative Effects Assessment (CEA), whic...
Article
Full-text available
An Integrated Testing Strategy for ecotoxicity assessment (ITS‐ECO) was developed to aid in the hazard and fate assessment of engineered nanomaterials (ENMs) deposited to marine environments using the bivalve, Mytilus spp., as a test species. CuO and TiO2 ENMs, either in pristine form (Core) or with functionalised coatings (PEG (polyethylene glycol...
Poster
Full-text available
An increasingly ice-free northern region is providing emerging opportunities for international transportation of goods utilising long envisaged Arctic sea routes. However, environmentalists have increasingly expressed concern about the potential impact of rising levels of ship traffic on the Arctic environment, contemplating socio-political issues...
Article
Full-text available
Human exposure to nano- and microplastics (NMPs) has raised major societal concerns, yet no framework to assess the risks of NMPs for human health exists. A substantial proportion of plastic produced worldwide is not properly disposed and persists in the environment for decades while degrading. Plastic degradation generates a size continuum of frag...
Article
Food availability in fjords is unusual among deep-sea environments (defined here as systems below 200 m) due to the increased availability of nutritional sources that are comparatively rare in the open sea, such as influxes of macrophytodetritus and terrestrial organic matter. In open waters, these deep-sea ‘organic falls’ have been shown to increa...
Article
Here we describe the development of an Integrated Approach to Testing and Assessment (IATA) to support the grouping of different types (nanoforms; NFs) of High Aspect Ratio Nanomaterials (HARNs), based on their potential to cause mesothelioma. Hazards posed by the inhalation of HARNs are of particular concern as they exhibit physical characteristic...
Article
The use of silver (Ag) and titanium dioxide (TiO2) nanomaterials (NMs) in industrial processes and consumer products has experienced considerable growth since the late 20th century. Throughout their lifecycle, both Ag NM and TiO2NM are released into the environment, with benthic systems anticipated to be the final sink. Their potential toxicity tow...
Chapter
Nanomaterials (NMs) can be released in the environment during various points of the life cycle (production, use, and disposal) of a nanoenabled product. Their particular physicochemical properties can be affected by environmental parameters modifying their behavior once they interact with biological systems. In the aquatic environment, NMs, dependi...
Article
Full-text available
The convergence of nanotechnology and biotechnology has led to substantial advancements in nano-biomaterials (NBMs) used in medical devices (MD) and advanced therapy medicinal products (ATMP). However, there are concerns that applications of NBMs for medical diagnostics, Materials 2020, 13, 4532 2 of 29 therapeutics and regenerative medicine could...
Article
Full-text available
Anthropogenic climate change presents a major challenge to coastal ecosystems. Mass population declines or geographic shifts in species ranges are expected to occur, potentially leading to wide-scale ecosystem disruption or collapse. This is particularly important for habitat-forming species such as free-living non-geniculate coralline algae that a...
Article
Full-text available
Nutrient enrichment is a significant cause of ecosystem change in coastal habitats worldwide. This study focuses on the change in a benthic macroinvertebrate community and environmental quality as assessed through different biotic indices following the construction of a sewage outfall pipe in the west of Scotland, from first implementation to seven...
Article
In this study the effect of copper oxide nanomaterials (CuO NMs), uncoated and with three different surface coatings (i.e. carboxylated, pegylated and ammonia groups), was evaluated on acute toxicity and accumulation dynamics in Daphnia magna. Biosorption and elimination rate constants were determined for D. magna following waterborne exposure to d...
Article
The exploitation of polylactide (PLA) nanocomposites (which integrate organically modified clays (organoclays) into polymers) in packaging for the cosmetics industry could provide a biodegradable alternative to the use of conventional plastics. In this study nanocomposites with a PLA polymer matrix and clay fillers organically modified with the qua...
Article
Organically modified clays can be used as nanofillers in polymer-clay nanocomposites to create bio-based packaging with improved strength and barrier properties. The impact of organic modification on the physico-chemical properties and toxicity of clays has yet to be fully investigated but is essential to ensure their safe use. Two organoclays, nam...
Article
Sorption of chemical substances to nanoparticles (NPs) in the aqueous phase strongly influence NP physicochemisty, and investigations of these complex interactions can provide important insight on environmental fate of NPs. The objective of this study was to use differences in copper (Cu) bioavailability to investigate aqueous‐phase sorption with N...
Article
Societies worldwide are investing considerable resources into the safe development and use of nanomaterials. Although each of these protective efforts is crucial for governing the risks of nanomaterials, they are insufficient in isolation. What is missing is a more integrative governance approach that goes beyond legislation. Development of this ap...
Article
Full-text available
The United Nations' Sustainable Development Goals have been established to end poverty, protect the planet, and ensure prosperity for all. Delivery of the Sustainable Development Goals will require a healthy and productive environment. An understanding of the impacts of chemicals which can negatively impact environmental health is therefore essenti...
Article
A major user of nanoparticles (NPs) is the pigment and ink industry, where NPs are incorporated into numerous products (e.g. paints, food, plastics, printers, personal care products, and construction materials). Assessment of NP toxicity requires potential impacts on human health and the environment to be evaluated. In this study, we examined the t...
Technical Report
Full-text available
The ECCLR Committee is carrying out this work in advance of the Rural Economy and Connectivity (REC) Committee’s forthcoming inquiry on aquaculture in Scotland, the terms of reference for which will be considered in the coming weeks. The ECCLR Committee’s focus is the report commissioned by SPICe and undertaken by SAMS Research Services Ltd (SRSL)....
Article
Assessing the safety of engineered nanomaterials (NMs) is paramount to the responsible and sustainable development of nanotechnology, which provides huge societal benefits. Currently, there is no evidence that engineered NMs cause detrimental health effects in humans. However, investigation of NM toxicity using in vivo, in vitro, in chemico, and in...
Article
As a consequence of increasing atmospheric CO2 and its subsequent sequestration, the oceans are undergoing changes that have not been seen for millennia, including temperature increases, ocean acidification, and localized alterations in salinity. Current methodologies for undertaking environmental-impact assessments may not be suitable for use unde...
Article
Nanoscale copper phthalocyanine (n-CuPc) is a pigment widely used in paints to enhance automobile coatings and to make colors transparent and more appealing to users. Despite the benefits, n-CuPc can potentially be released into the environment and pose risks in occupational settings. Assessing the toxicity of released n-CuPc-containing fragments i...
Article
One of the most widely used approaches for improving drug permeation across the stratum corneum barrier of the skin is the use of chemical penetration enhancers, such as surfactants. In this study, two anionic surfactants, named C12-OPK and C18-OPK, were synthesized via condensation of itaconic acid and fatty amines, with C12 and C18 alkyl chains,...
Article
Full-text available
Regulatory ecotoxicity testing of chemicals is of societal importance and a large effort is undertaken at the OECD to ensure that OECD test guidelines (TGs) for nanomaterials (NMs) are available. Significant progress to support the adaptation of selected TGs to NMs was achieved in the context of the project MARINA (http://www.marina-fp7.eu/) funded...
Article
The European Commission and its independent Scientific Committee on Health and Environmental Risks (SCHER) published their final Opinion on estimates of the amount of toy materials ingested by children. The SCHER was asked to review available data on the ingestion of the following three types of toy material by children, and evaluate whether the in...
Poster
Full-text available
The objective of this study was to investigate the toxicity of a range of CuO NMs using Daphnia magna. Biochemical endpoints were assessed in both acute and chronic toxicity tests. Oxidative stress is investigated in relation to its possible role in the production of tissue damage in D. magna The activities of three antioxidant enzymes, catalase (C...
Poster
Full-text available
Very good results in the decomposition of SAs drugs in the aquatic environment were achieved by ozonation and using an oxidation process with unspecific peroxygenase from Agrocybe aegerita (AaeUPO) (Lemańska-Malinowska, 2015). Nonetheless, special attention should be paid to the risk of by-products’ formation, which may cause potential toxic effect...
Conference Paper
Full-text available
Naturally occurring particulates within the nano-size range are very abundant in surface waters and among these are mineral clay particles. Engineered nanoparticles (NPs) that are released into surface waters will undoubtedly interact with naturally occurring particulates; however, investigations of the effects of these interactions on NP toxicity...
Conference Paper
Full-text available
Flumes offer the ability to study Ag NM removal and persistence behaviour in controlled and potentially ‘environmentally relevant’ scenarios. Studying removal rates within flow systems may produce fate descriptors to translate processes into useful models which will help with exposure assessment in realistic conditions. The aim of this research was...
Conference Paper
Production of reactive oxygen species (ROS) has been described as a general pathway of toxicity induced by various metal based engineered nanomaterials and other chemicals leading to oxidative stress Coating-related changes in three antioxidant enzymes activities in the freshwater flea Daphnia magna were assessed, based on information obtained in a...
Article
Engineered nanomaterials (ENMs) are increasingly entering the environment with uncertain consequences including potential ecological effects. Various research communities view differently whether ecotoxicological testing of ENMs should be conducted using environmentally relevant concentrations-where observing outcomes is difficult-versus higher ENM...
Article
Full-text available
The European Union-United States Communities of Research were established in 2012 to provide a platform for scientists to develop a "shared repertoire of protocols and methods to overcome nanotechnology environmental health and safety (nanoEHS) research gaps and barriers" (www.us-eu.org/). Based on work within the Ecotoxicology Community of Researc...
Conference Paper
Suite of biochemical assays to derive commonalities and differences in silver NPs and AgNO3, as well as how this may feed into regulatory frameworks and QSARs under REACH. Journal publication in progress. Contact for more information, abstract and conference paper upload submitted soon on RG.
Article
Impact of aging on nanoparticle toxicity in real matrices is scarcely investigated due to a lack of suitable methodologies. Herein, the toxicity of pristine and aged silver nanoparticles (Ag NPs) to a bioluminescent Pseudomonas putida bioreporter was measured in spiked crude and final wastewater samples (CWs and FWs, respectively) collected from fo...
Article
In this paper we report for the first time on the suitability of surface plasmon resonance imaging (SPRi) for performing ecotoxicity testing of nanoparticles (NPs). Specifically, the impact of silver NPs (using Ag NM-300K) and ions (using AgNO3 salt) on Salmonella Enteritidis growth was assessed in Luria Bertani medium using the culture-capture-mea...
Article
Full-text available
ENPRA was one of the earlier multidisciplinary European Commission FP7-funded projects aiming to evaluate the risks associated with nanomaterial (NM) exposure on human health across pulmonary, cardiovascular, hepatic, renal, and developmental systems. The outputs from this project have formed the basis of this review. A retrospective interpretation...
Technical Report
Full-text available
In Opinion I on Synthetic Biology (SynBio), the three Scientific Committees SCHER, SCENIHR and SCCS answered three questions from the European Commission on the scope, definition and identification of the relationship between SynBio and genetic engineering and the possibility of distinguishing the two. The definition reads: Synthetic Biology is the...
Article
Full-text available
An engineered nanomaterial (ENM) may actually consist of a population of primary particles, aggregates and agglomerates of various sizes. Furthermore, their physico-chemical characteristics may change during the various life-cycle stages. It will probably not be feasible to test all varieties of all ENMs for possible health and environmental risks....
Article
Full-text available
This study investigated the bioaccumulation dynamics of silver nanoparticles (Ag NPs) with different coatings (polyvinyl pyrrolidone, polyethylene glycol and citrate), in comparison with aqueous Ag (added as AgNO3), in a simplified freshwater food chain comprising the green alga Chlorella vulgaris and the crustacean Daphnia magna. Algal uptake rate...
Article
These studies were undertaken in order to propose and test new methods for the assessment of the acute hazard of ZnO nanoparticles (NPs) to the sediment dwelling oligochaete worm Lumbriculus variegatus. In order to support the developing nanotechnology sector, comprehensive studies must be conducted to assess the toxicity of nanomaterials (NMs) usi...
Technical Report
Full-text available
In Opinion I on synthetic biology (SynBio), the three non-food Committees of the European Union SCHER, SCENIHR, and SCCS answered the first 3 out of 11 questions from the European Commission on scope, definition and identification of the relationship between SynBio and genetic engineering, and the possibility of distinguishing the two. In this sec...
Conference Paper
Full-text available
Given the widespread use of silver nanomaterials (Ag NM), their release, whether accidental or intentional, into the environment is inevitable. At this point, Ag NPs long term threat to freshwater ecosystems is unclear. Current research shows NM fate and toxicity is affected by water chemistry, the presence of organic matter, sediments and other po...
Article
Full-text available
Frameworks commonly used in trace metal ecotoxicology (e.g. biotic ligand model (BLM) and tissue residue approach (TRA)) are based on the established link between uptake, accumulation and toxicity, but similar relationships remain unverified for metal-containing nanoparticles (NPs). The present study aimed to (i) characterize the bioaccumulation dy...
Article
Full-text available
Nanosilver and other forms ofof silver are widely used nowadays for their antibacterial activity. The characteristics and the use of different forms of silver (including silver salts, silver oxides and silver materials appearing as silver wires, silver nanoparticles (Ag-NP) and others) are used in consumer and medical products may have different ph...
Technical Report
Full-text available
In Opinion I on SynBio, SCHER, SCENIHR, and SCCS answered three questions from the European Commission on scope and definition. Opinion I focused on identifying the relationship between SynBio and GM, and the possibility of distinguishing between the two. In this second opinion, SCs are asked, in another five questions, to address what the implica...
Article
Marine Spatial Planning attempts to develop integrated planning frameworks for the management of activities within marine ecosystems and support sustainable development. This study demonstrates the application and testing of an existing multiple-use zoning scheme within Scottish territorial waters. The zoning scheme developed is based on integratin...
Article
Full-text available
The subject of nanomaterials is very topical,with advances in knowledge made at a very rapid pace, making dissemination of this new knowledge a need of the hour. Although it is widely recognised that nanotechnology is playing a key role in many areas of societal endeavour, it is still unclear what risks certain nanomaterials may pose to humans and...
Article
Reliable ecosystem quality assessment of marine environments is increasingly important due to mounting pressures attributable to human activities. Biotic indices are widely used in studies to describe communities and indicate the ecological state of systems. This study focuses on benthic macroinvertebrate-based biotic indices for the assessment of...