Teerthanath Srinivas

Nitte University · Department of Pathology

Neonatal hepatitis (NH) and biliary atresia (BA) are the most common causes of cholestasis in infancy. NH is a nonobstructive type of neonatal cholestatic syndrome manifesting with hepatitis. BA is an obstructive inflammatory syndrome of the extrahepatic biliary tract. BA accounts for 40% of cholestasis in infancy, and NH accounts for 10%–15% cases...

Lateral aberrant ectopic thyroid is very rare, comprising only 1%–3% of all the ectopic thyroid tissue. Clinically, these lesions are mistaken for lymph node swelling or metastatic tumour. Primary carcinoma in lateral aberrant ectopic thyroid with normal active native thyroid is very uncommon. We report a case of papillary carcinoma in lateral aber...

Introduction and Aim: Various non-neoplastic and neoplastic lesions occur in the kidney. Pathological assessment of gross and microscopic features in nephrectomy specimens is essential for diagnosis and predicts the prognosis in malignant tumours. Materials and Methods: Case records of 46 nephrectomy specimens received between two-year periods were...

Thrombosis of both umbilical arteries is a rare condition, less common than venous thrombosis. They cause a lot of complications during and after delivery. Umbilical artery thrombosis is associated with both maternal predisposing factors and cord abnormalities and is commonly seen in male fetuses. Presenting symptoms are those of intrauterine growt...

Background Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of endometrial gland and stroma outside the uterus. It is commonly seen in the reproductive age group and is a leading cause of infertility. Patients present with chronic pelvic pain, menstrual abnormalities, dyspareunia, or mass per abdomen. Surgical excis...

Primitive neuroectodermal tumors (PNET) is an aggressive, rapidly progressing and metastatic tumor. It rarely arises from the kidney and has an incidence of less than 1%. These are usually mistaken for a wide variety of other small round cell tumors. Young adults and children are commonly affected and have an aggressive course. These tumors are mis...

Pigmented villonodular synovitis (PVNS) is a rare benign neoplasm involving the synovial joints and tendon sheaths. It can be classified into localised and diffuse type. The diffuse type of PVNS is larger and very aggressive, clinically mimicking as soft tissue sarcoma. Radiological investigation can aid in knowing the relation of the mass to the j...

Pleomorphic carcinoma is a very rare subtype of pulmonary sarcomatoid carcinoma. It is an aggressive primary lung carcinoma that accounts for about <0.4% of lung tumors. The tumor usually recurs, resulting in a poor prognosis even after complete resection. Herein, we report an extremely rare case of an advanced pleomorphic carcinoma of the lung whi...

Mucinous cystic neoplasms of the liver involving the extrahepatic biliary tract is a rare slow-growing benign neoplasm of biliary system that has an early clinical presentation with obstructive jaundice. These tumors have a high risk of malignant transformation, which is difficult to diagnose preoperatively by radiology or endoscopy. We present a 3...

Heterotopia is the presence of a particular tissue at a nonphysiological site. The most common sites are gastric, pancreatic, and splenic heterotopias. While liver heterotopias are rare, intrathoracic heterotopias are much more limited. It is usually reported incidentally on imaging investigations or at autopsy. There is a high incidence of maligna...

Context: Parotid gland tumors account for 80% of all salivary gland neoplasms. Most parotid masses are operated on before obtaining the final histological diagnosis, which complicates the management of the facial nerve damage during parotid surgery. Aims: The aim of this study is to analyze the age- and gender-wise incidence of parotid gland tum...

A lady presented with indolent slowly spreading erythematous nodule on the left external ear which on histopathology showed dense monomorphic lymphoid cells in the dermis. No epidermotropism or angioinvasion was seen. Immunohistochemistry showed that the infiltrating lymphoid cells were CD8+ but CD4-. Majority of the cases of cutaneous T-cell lymph...

Background: Malaria continues to be an important public health problem in developing and underdeveloped countries with high morbidity and mortality. It continues to be one of the major public health problems in India. Plasmodium vivax is the major parasite type causing malaria and Plasmodium falciparum is the major cause of serious and complicated...

Background: Granulomatous dermatosis shares the histological finding of granuloma formation; it is usually formed because of the persistence of a non-degradable product of active hypersensitivity. The identical histological picture may be produced by several causes, which pose a diagnostic challenge to dermatopathologist, Present study aims at clas...

Background: Groin hernia is a very common type abdominal wall hernia encountered in surgical practice. Irreducibility, obstruction and strangulation are its commonest complications which usually presents as acute emergencies. Emergency repair of complicated hernias is associated with poor prognosis and a high rate of post-operative complications ev...

Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and accounts for 90% of head and neck malignancies. Intracranial metastases of SCC are extremely rare. We are reporting a case of 55-year-old female with history of recurrent swelling over right side of forehead which was previously reported as cylindroma. CT scan of h...

The incidence of hydatidiform mole is 1 per 1000 pregnancies. The occurrence of hydatidiform mole in ruptured tubal pregnancy is very rare. We report an unusual case of molar pregnancy in the right fallopian tube which presented as an adherent adnexal mass. The present case conveys the importance of histological examination of products of conceptio...

The oral cavity mucosal tissue alteration can manifest in a variety of lesions where great majority of localized overgrowths of the oral mucosa are considered to be reactive rather than neoplastic in nature. Many of these lesions can be identified as specific entities on the basis of their histopathological features. In our present study, we have e...

Fine needle aspiration cytology (FNAC) is an important diagnostic tool for swellings in the thyroid, salivary gland, breast lump and enlarged lymph nodes. Very few studies have been done to explore the potential of FNAC in the diagnoses of intraoral lesions. Hence the present study was done to find out the efficacy of FNAC in the diagnosis of intra...

Metaplastic carcinoma of breast (MBC) is a rare and aggressive type of invasive breast cancer. As it encompasses a variety of distinct histopathologic designations, diagnostic challenges abound. We present a case report of metaplastic carcinoma with extensive chondroid differentiation. This case merits presentation because of its rarity and difficu...

Osteosarcomas are relatively rare in jaws and maxillomandibular lesions in children are distinctly uncommon. Telengiactic osteosarcomas in jaws are still a very rare variant and till now just 3 cases are reported in English literature. Herein, we report the first case of telangiectatic osteosarcoma occurring in mandible in pediatric patient. Patien...

Primary thyroid haemangioma is extremely rare, with only countable cases having been previously reported. We are reporting a case of 38-year-old male with history of diffuse thyroid swelling in front of the neck, which was firm to hard in consistency. Ultrasonography (USG) displayed an enlarged left thyroid with anechoic / isoechoic nodule and foci...

Background: Mediastinal tumours are uncommon lesions encountered in clinical practice. There has been a significant increase in the incidence of malignant mediastinal tumours over the past four decades. The presentation varies from asymptomatic lesions detected incidentally on imaging to severe life threatening presentations. Aim and Objectives: Th...

Primary fallopian tube carcinoma is an extremely uncommon neoplasm of the female genital tract. Primary Fallopian Tube Carcinoma (PFTC) has a clinical and a histological resemblance to Epithelial Ovarian Cancer (EOC). We are reporting a case of PFTC in a 55 year old tubectomized, postmenopausal woman with the non-specific complaints of a watery vag...

Carcinoma of the male breast is a relatively rare disease that accounts for less than 1% of all the cases of cancer in men. Intracystic Papillary Carcinoma (IPC) is an extremely rare disease of the male breast, with a few case reports. The prognosis is excellent for the patients who are diagnosed with IPC, regardless of whether the tumour is in-sit...

Sertoli-Leydig cell tumor of ovary is a gonadal tumour of the sex cord-stromal type. It is a rare tumor comprising 0.1 to 0.5% of all ovarian tumours. Peritoneal cytology has been well established as a diagnostic and staging tool in the management of the common epithelial tumours of ovary. Germ cell, mesenchymal, and sex-cord stromal tumours are mu...

AIM: The present study was undertaken to evaluate noni fruit juice for its protective effects on gentamicin-induced nephrotoxicity in rats. METHODS:Wistar albino rats of either sex, weighing 150-200g were divided into 4 groups; normal saline, gentamicin 80 mg/kg, i.p.,i for 8 days, noni fruit juice 5 and 10 mg/kg, p.o., for 8 days, noni fruit juice...

Phaeohyphomycoses are rare, opportunistic, fungal infections which are usually seen in immunocompromised individuals. These are primarily caused by soil saprophytes, plant pathogens, and contaminants which live in the environment. In humans, cutaneous infections are very common; however, the involvement of lungs, sinuses, eyes, bone, and the centra...

The present study evaluates the nephroprotective effects of ursolic acid in a murine model of gentamicin induced renal damage. Wistar albino rats of either sex, weighing 150-200 g were divided into 5 groups; normal saline, gentamicin 80 mg/kg, intraperitoneally for 8 days, ursolic acid at 2, 5, and 10 mg/kg, per oral for 8 days, ursolic acid admini...

Granulomatous inflammation is a distinctive pattern of chronic inflammation that is encountered in a limited number of infectious and non-infectious conditions. Recognisation of granulomatous pattern and finding the etiology in a biopsy specimen is very important for specific treatment and outcome of the disease. We aimed at finding the etiology of...

Lymphatic filariasis is common in tropical countries and is endemic in South India. Filariasis presenting with pericardial effusion is rare, coexisting with spindle cell thymoma is still very rare. We report a case of a 53-year-old male who was admitted to cardiac intensive care unit with severe breathless since two days. Cardiac Echocardiogram sho...

Background and objectives: Salivary gland tumours account for 2-6.5% of all the neoplasms of the head and neck. Fine needle aspiration cytology (FNAC) is being increasingly used in the diagnosis of salivary gland tumours. The objective of this study was to evaluate the diagnostic accuracy and the sensitivity and specificity of FNAC in various saliv...

Liposarcoma in the inguinal region though rare are clinically significant lesions. Preoperative diagnosis is difficult since the clinical findings are very similar to that of inguinal hernia. We report a rare case of Liposarcoma of the spermatic cord in 85 year old male, clinically diagnosed as left sided indirect inguinal hernia. Surgical excision...

Chromophobe renal cell carcinoma is a relatively uncommon variant of renal cell carcinoma. Eosinophilic variant of chromophobe renal cell carcinoma (EVCRCC) is still less frequent and is composed predominantly of small to medium-sized cells with abundant granular eosinophilic cytoplasm. We report two cases of EVCRCC, with one having a rare associat...

Mixed choristomas of the oral cavity are uncommon lesions that show a variety of clinical presentations, histological appearance and growth patterns. Mixed choristoma with cleft palate is a very rare developmental malformation. We report an unusual case of mixed choristoma in posterior tongue and left submandibular region in a 6-month-old male baby...

Paecilomyces is a colonizing fungal species which usually causes keratitis, endocarditis, sinusitis, nephritis, fungemia, cutaneous, and subcutaneous infections in immunocompromised host. Very rarely, it causes similar infection in immunocompetent host without any risk factors. We report a case of maxillary sinusitis due to Paecilomyces lilacinus i...

Rhinosporidiosis is a granulomatous disorder caused by Rhinosporidium seeberi. It frequently involves the nasopharynx and occasionally affects the skin. We hereby report a case of 46-year-old male who presented with multiple cutaneous plaque-like lesions with nasal obstruction. On examination, multiple cutaneous lesions were found to be present on...

Primary intracystic squamous cell carcinoma (SCC) of the breast is an extremely rare entity and has a low incidence in comparison with other breast cancers. We report a rare case of primary intracystic SCC in a 45-year-old woman who presented with a cystic lump in the right breast. Cytological smears of the fluid aspirated from the breast tumor rev...

Onychomycosis is a common problem noticed in clinical practice. Currently available standard laboratory methods show inconsistent sensitivity; hence there is a need for newer methods of detection. This study involves comparison of standard laboratory tests in the diagnosis of onychomycosis, namely, potassium hydroxide mount (KOH mount) and mycologi...

Mesenchymal chondrosarcomas (MCs) are rare malignant neoplasms that can arise from both soft and hard tissues. They are distinct tumors arising in unicentric or multicentric locations. They reveal unusual clinical behavior, characteristic histopathological features, and poor prognosis with late recurrences. Here is a report of a rare case of MC tha...

Melanoacanthoma is a benign mixed tumor of melanocytes and keratinocytes. It has been regarded as a rare variety of Seborrheic keratosis. A 50-year-old male presented with multiple asymptomatic pigmented growths on the lower abdomen, inner thighs, external genitals and perianal areas. Histopathology revealed features of melanoacanthoma. The case is...