Taylor Kampert

Taylor Kampert
University of Illinois, Urbana-Champaign | UIUC · Department of Bioengineering

Master of Science

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4
Publications
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65
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Introduction
Taylor Kampert currently works at the Department of Bioengineering, University of Illinois, Urbana-Champaign. TTheir most recent publication is 'Phenotypically Screened Carbon Nanoparticles for Enhanced Combinatorial Therapy in Triple Negative Breast Cancer'.

Publications

Publications (4)
Article
Full-text available
Various cancer cells have been demonstrated to have the capacity to form plasmonic gold nanoparticles when chloroauric acid is introduced to their cellular microenvironment. But their biomedical applications are limited, particularly considering the millimolar concentrations and longer incubation period of ionic gold. Here, we describe a simplistic...
Article
Pathogenesis of many cancer is driven by the Myc oncoprotein, its dimerization with Max, and the binding of this heterodimer to E-Boxes of target genes. The systemic effectiveness of potent small molecule inhibitors of Myc-Max dimerization has been lim-ited by poor bioavailability, rapid metabolism, and inadequate target site penetration. The poten...
Article
Introduction: Triple negative breast cancer (TNBC) is a highly aggressive type of breast cancer with high resistance to current standard therapies. We demonstrate that phenotypically stratified carbon nanoparticle is highly effective in delivering a novel combinatorial triple drug formulation for synergistic regression of TNBC in vitro and in vivo...
Article
Full-text available
We report the ability of a novel combinatorial therapy obtained from nanoparticles of hyperstar polymers encompassing drugs to selectively target triple negative breast cancer (TNBC) cell proliferation through STAT3 and topoisomerase-II pathways. This nano-cocktail was at least two to four fold better than the individual drugs and 6-20 times more s...

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