
Tarun AnumolAgilent · Market Development
Tarun Anumol
Ph.D., University of Arizona
About
43
Publications
11,690
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,288
Citations
Introduction
Additional affiliations
July 2010 - March 2015
Publications
Publications (43)
The presence of pharmaceuticals, hormones, pesticides and industrial contaminants collectively termed as trace organic compounds (TOrCs) in wastewater has been well-documented in USA, Europe, China and other regions. However, data from India, the second most populous country in the world is severely lacking. This study investigated the occurrence a...
Trace organic compounds (TOrCs) continue to be detected in drinking water, and their recalcitrance makes them difficult to attenuate without installing expensive advanced treatment processes. Because human consumption is a small portion of net household water use, point-of-use (POU) devices may provide additional security against drinking water con...
This study investigated the applicability of bulk organic parameters like dissolved organic carbon (DOC), UV absorbance at 254 nm (UV254), and total fluorescence (TF) to act as surrogates in predicting trace organic compound (TOrC) removal by granular activated carbon in water reuse applications. Using rapid small-scale column testing, empirical li...
Trace organic compounds (TOrCs) have been detected in drinking water sources for several years, raising concerns due to their potential risks to public health. The main contributor of TOrCs to drinking water is through wastewater discharges. However, there are several hundred TOrCs currently known with numerous new organic chemicals being released...
The present study investigated the impact of filtration, creaming and pasteurization on the authentication of the botanical origin of honey using the dilute-and-shoot method in liquid chromatography coupled to mass spectrometry (LC-MS). The analytical method performances were satisfactory (analyte recoveries ranging from 95 % to 103 % and inter-day...
This study explores the GAC adsorption of perfluorooctanoic acid
(PFOA) and perfluorooctanesulfonic acid (PFOS), that stands out as the most frequently produced and detected compounds belonging to the class of poly- and perfluoroalkyl substances (PFAS). Experiments were performed on three distinct
wastewaters (WW-1, WW-2, WW-3) employing rapid smal...
Simultaneous identification and quantification of per- and polyfluoroalkyl substances (PFAS) were evaluated for three quadrupole time-of-flight mass spectrometry (QTOF) acquisition methods. The acquisition methods investigated were MS-Only, all ion fragmentation (All-Ions), and automated tandem mass spectrometry (Auto-MS/MS). Target analytes were t...
A method is described using a triple quadrupole LC–MS instrument with isotopic dilution to obtain the highest accuracy and confidence for analysis of per- and polyfluoroalkyl substances (PFAS) in water. Excellent method spike recoveries and robustness were found in wastewater.
This work critically compared the removal of fluorescing PARAFAC components and selected pharmaceuticals (carbamazepine, fluoxetine, gemfibrozil, primidone, sulfamethoxazole, trimethoprim) from a tertiary wastewater effluent by different UV- and ozone-based advanced oxidation processes (AOPs) operated at pilot-scale. Investigated AOPs included UV/H...
Human exposure to mixtures of per- and polyfluoroalkyl substances (PFASs) constitute an important issue in environmental epidemiology and the adoption of more holistic approaches to reduce the uncertainties associated with their human health effects is a critical research need. The exposome, defined as the totality of environmental (i.e., nongeneti...
Much of the seafood that humans consume comes from estuaries and coastal areas where microplastics (MPs) accumulate, due in part to continual input and degradation of plastic litter from rivers and runoff. As filter feeders, oysters (Crassostrea virginica) are especially vulnerable to MP pollution. In this study, we assessed MP pollution in water a...
Endocrine active contaminants (EACs) in environmental samples can pose a range of toxicological threats to ecosystems, especially through their impacts on reproductive pathways mediated by the estrogen receptor. The physicochemical properties of known organic EACs vary greatly and typically require different sample preparation techniques to identif...
A quantitative method for the determination of per- and polyfluoroalkyl substances (PFAS) using liquid chromatography (LC) tandem mass spectrometry (MS/MS) was developed and applied to aqueous wastewater, surface water, and drinking water samples. Fifty-three PFAS from 14 compound classes (including many contaminants of emerging concern) were measu...
Targeted metabolomics aims to provide a new approach to investigate metabolites and gather both qualitative and quantitative information. We describe a protocol for extraction and analysis of plant metabolites, specifically 13 secondary metabolites (antioxidants) using liquid chromatography coupled to triple quadrupole mass spectrometry (LC-MS/MS),...
The increasing usage of nanopesticides in agriculture poses a concern to plant crops due to unknown implications of engineered nanomaterials (ENMs). Targeted metabolomics can provide both qualitative and quantitative information at a molecular level to investigate the response of plants to emerging environmental stressors, such as nanopesticides. H...
This study investigated, using rapid small-scale column testing, the breakthrough of dissolved or-ganic matter (DOM) and eleven emerging organic contaminants (EOCs) during granular activat-ed carbon (GAC) filtration of different water qualities, including wastewater, surface water and synthetic water (riverine organic matter dissolved in deionized...
Chemical exposure in household dust poses potential risks to human health but has been studied incompletely thus far. Most analytical studies have focused on one or several compound classes, with analysis performed by either liquid or gas chromatography coupled with mass spectrometry (LC-MS or GC-MS). However, a comprehensive investigation of indiv...
Ozone oxidation has been demonstrated to be an effective treatment process for the attenuation of trace organic compounds (TOrCs); however, predicting TOrC attenuation by ozone processes is challenging in wastewaters. Since ozone is rapidly consumed, determining the exposure times of ozone and hydroxyl radical proves to be difficult. As direct pota...
Veterinary drug residues in animal-derived foods must be monitored to ensure food safety, verify proper veterinary practices, enforce legal limits in domestic and imported foods, and for other purposes. A common goal in drug residue analysis in foods is to achieve acceptable monitoring results for as many analytes as possible, with higher priority...
The Mississippi River drainage basin includes the Illinois, Missouri, Ohio, Tennessee, and Arkansas rivers. These rivers drain areas with different physiography, population centers, and land use, with each contributing a different suites of metals and wastewater contaminants that can affect water quality. In July 2012, we determined 18 elements (Be...
Efficient strategies are required to implement comprehensive suspect screening methods using high-resolution mass spectrometry within environmental monitoring campaigns. In this study, both liquid and gas chromatography time-of-flight mass spectrometry (LC-QTOF-MS and GC-QTOF-MS) were used to screen for >5,000 target and suspect compounds in the Sa...
This study demonstrated the use of nanofiltration (NF) membrane with pre-ozonation for surface water brine treatment. Pre-ozonation, used for fouling control, with relatively low ozone doses (0.1−0.4 mg O3/mg DOC ratios) significantly reduced organic fouling potential. A classical pore blocking model revealed that the dominant fouling mechanism was...
The removal of trace organic compounds (TOrCs) is of growing interest in water research and society. Powdered activated carbon (PAC) has been proven to be an effective method of removal for TOrCs in water, with the degree of effectiveness depending on dosage, contact time, and activated carbon type. In this study, the attenuation of TOrCs in three...
Hepatic multidrug resistance-associated protein 2 (MRP2) provides the biliary elimination pathway for many xenobiotics. Disruption of this pathway contributes to retention of these compounds and may ultimately lead to adverse drug reactions. MRP2 mislocalization from the canalicular membrane has been observed in nonalcoholic steatohepatitis (NASH),...
This study investigated the applicability of different techniques for fluorescence excitation/emission matrices data interpretations, including peak-picking method, fluorescence regional integration and PARAFAC modelling, to act as surrogates in predicting emerging trace organic compounds (ETOrCs) removal during conventional wastewater treatments t...
Methylglyoxal (MG) is a highly reactive dicarbonyl compound involved in the formation of advanced glycation endproducts. Levels of MG are elevated in patients with type-2 diabetes mellitus (T2DM), and advanced glycation endproducts (AGEs) have been implicated in the progression of diabetic complications. The anti-hyperglycemic drug metformin (MF) h...
Wastewater compounds are frequently detected in urban shallow groundwater. Sources include sewage or reclaimed wastewater, but origins are often unknown. In a prior study, wastewater compounds were quantified in waters sampled from shallow groundwater wells in a small coastal California city. Here, we resampled those wells and expanded sample analy...
A rapid LC/MS/MS method for the detection of trace organic compounds in waste-water using direct aqueous injection and only 80 µL of sample has been used to identify a set of 20 indicator compounds for their presence in wastewater effluent. Cycle time was less than 14 minutes, and the method reporting limits (MRLs) of most compounds were from 3 to...
A combination of surrogate parameters and indicator compounds were measured to predict the removal efficiency of trace organic compounds (TOrCs) using low pressure (LP)-UV/H2O2 advanced oxidation process (AOP), engaged with online sensor-based monitoring system. Thirty-nine TOrCs were evaluated in two distinct secondary wastewater effluents in term...
Realized and potential threats of water scarcity due in part to global climate change have increased the interest in potable reuse of municipal wastewater. Recalcitrant trace organic compounds (TOrCs), including pharmaceuticals and endocrine disrupting compounds in wastewater are often not efficiently removed by conventional wastewater treatment pr...
Landfill leachate samples (n=11) were collected from five USA municipal solid waste (MSW) landfills and analyzed for ten trace organic pollutants that are commonly detected in surface and municipal wastewater effluents (viz., carbamazepine, DEET, fluoxetine, gemfibrozil, PFOA, PFOS, primidone, sucralose, sulfamethoxazole and trimethoprim). Carbamaz...
Hepatic drug metabolizing enzymes and transporters play a crucial role in determining the fate of drugs, and alterations in liver function can place individuals at greater risk for adverse drug reactions (ADRs). We have shown that nonalcoholic steatohepatitis (NASH) leads to changes in the expression and localization of enzymes and transporters res...
Reactive dicarbonyls such as methylglyoxal (MG) are elevated in type‐2 diabetes mellitus (T2DM) patients and their ability to covalently modify proteins contributes to diabetic complications. The T2DM first‐line drug metformin (MF) significantly reduces diabetes‐related endpoints and mortality more effectively than other glucose‐lowering medication...
Background
The widespread utilization of organic compounds in modern society and their dispersion through wastewater have resulted in extensive contamination of source and drinking waters. The vast majority of these compounds are not regulated in wastewater outfalls or in drinking water while trace amounts of certain compounds can impact aquatic wi...