Taoufiq Benali

Taoufiq Benali
Polydisciplinary Faculty of Safi-Cadi Ayyad University · Biology

Professor

About

43
Publications
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Introduction
Taoufiq BENALI is a Professor at the Polydisciplinary Faculty of Safi, Cadi Ayyad University, Morocco. His research focuses on ethnobotanical studies of Moroccan medicinal plants; their chemical composition as well as the investigation of their pharmacological properties (antibacterial, antioxidant, antifungal, anticancer, …); and their biotechnological applications.

Publications

Publications (43)
Article
Quinic acid is a cyclohexanecarboxylic acid commonly extracted from different parts of medicinal plants including Haematocarpus validus, Hypericum empetrifolium, Achillea pseudoaleppica, Rumex nepalensis, Phagnalon saxatile subsp. saxatile, Coffea arabica, Ziziphus lotus L, and Artemisia annua L… etc. Currently, in vitro and in vivo pharmacological...
Article
Traditional herbal medicine is still used for basic healthcare by a significant portion of the population in developing countries. This study aimed to explore the medicinal plant's diversity and to document related traditional knowledge in the Safi region of Morocco. We used semi-structured questionnaires to interview 222 informants living in the s...
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The search for natural plant-based products as new pharmacological alternatives to treat various human pathologies has taken on great importance for researchers and research laboratories. In this context, research has intensified to extract and identify natural molecules endowed with biological effects. The objective of this study is to review the...
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A flavone, chrysoeriol is synthetized in several plant species. It comes from several natural sources, especially medicinal plants. The identification and isolation of this compound has been carried out and verified by several research teams using different spectral methods. It seems that the concentration of this molecule is variable and fluctuati...
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Salvia officinalis is a medicinal plant used to treat some diseases, including microbial infections and diabetes. Different studies showed the biological and pharmacological properties of this species. The aim of this study was the determination of the chemical compounds of S. officinalis essential oils and the investigation of their antimicrobial,...
Article
Grapevine crown gall, caused by Allorhizobium vitis (A. vitis) and fire blight, caused by Erwinia amylovora (E. amylovora) of rosaceous plants, have been recognized as serious bacterial diseases and responsible for major crop losses in grapevine (Vitis vinifera L.), pear (Pyrus communis L.) and apple (Malus domestica Borkh.) worldwide. To develop a...
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Daucosterol is a saponin present in various natural sources, including medicinal plant families. This secondary metabolite is produced at different contents depending on species, extraction techniques, and plant parts used. Currently, daucosterol has been tested and explored for its various biological activities. The results reveal potential pharma...
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Pinosylvin (3,5-dihydroxy-trans-stilbene), a natural pre-infectious stilbenoid toxin, is a terpenoid polyphenol compound principally found in the Vitaceae family in the heartwood of Pinus spp. (e.g., Pinus sylvestris) and in pine leaf (Pinus densiflora). It provides defense mechanisms against pathogens and insects for many plants. Stilbenoids are m...
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Cancer is a complex pathology that causes a large number of deaths worldwide. Several risk factors are involved in tumor transformation, including epigenetic factors. These factors are a set of changes that do not affect the DNA sequence, while modifying the gene’s expression. Histone modification is an essential mark in maintaining cellular memory...
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The SARS-CoV-2 Omicron variant has spread rapidly and is considered the predominant variant in the world, and its main characteristic is related to evade immunity from natural infection or vaccines, due to its multiple mutations in the spike protein. On the other hand, medicinal plants have been used as alternatives therapies to ameliorate some sig...
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The main purpose of this study was to determine the content of various extracts of Pulicaria mauritanica and Lavandula mairie on polyphenols and flavonoids, and also to assess their antioxidant and antibacterial activities. The various extracts were prepared from aerial part using solvents of different polarity (hexane, ethyl acetate and ethanol),...
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Nanoparticles (NPs) are tiny substances that can exist in the soil with different forms at different concentrations. In general, they present enormous effects on the growth, physiology, and molecular responses in plants. Indeed, they can penetrate the roots, stem, and leaves via different ways like stomata, plasmodesmata, xylem, and phloem and thro...
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Bacterial strains have developed an ability to resist antibiotics via numerous mechanisms. Recently, researchers conducted several studies to identify natural bioactive compounds, particularly secondary metabolites of medicinal plants, such as terpenoids, flavonoids, and phenolic acids, as antibacterial agents. These molecules exert several mechani...
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Carvone is a monoterpene ketone contained in the essential oils of several aromatic and medicinal plants of the Lamiaceae and Asteraceae families. From aromatic plants, this monoterpene is secreted at different concentrations depending on the species, the parts used, and the extraction methods. Currently, pharmacological investigations showed that...
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The plant faces different pedological and climatic challenges that influence its growth and their enhancement. While, plant-microbes interactions throught the rhizosphere offer several privileges to this hotspot in the service of plant, by attracting multi-beneficial mutualistic and symbiotic microorganisms plant growth-promoting rhizobacteria (PGP...
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Plants and microbes interact with each other via different chemical signaling pathways. At the risophere level, the microbes can secrete molecules, called elicitors, which act on their receptors located in plant cells. The so-called elicitor molecules as well as their actions differ according to the mcirobes and induce different bilogical responses...
Chapter
Terpenoids are volatile compounds synthetized and secreted by several organisms, in particularly by medicinal plants as secondary metabolites. These phytochemical compounds have shown several benefits in healthcare by their numerous pharmacological properties. Indeed, they have antibacterial, antifungal, antioxidant, antiviral, anticancer, and anti...
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Ethnopharmacological relevance: Centaurium erythraea is an important medicinal plant in many countries, e.g. Morocco, Algeria, Italy, Spain, Portugal, and countries of Balkan Peninsula. It is used in folk medicine to treat various illnesses. It is also used as an antiapoplectic, anticoagulant, anticholagogue, antipneumonic, hematocathartic, and as...
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Origanum elongatum L. is an endemic aromatic and medicinal plant. This work reports previous studies on O. elongatum concerning its taxonomy, botanical description, geographical distribution, bioactive compounds, toxicology, and biological effects. Chemical analyses showed that O. elongatum contains different chemical compounds, in particular volat...
Article
Ethnopharmacological relevance: Pinus halepensis Mill., is a Mediterranean medicinal plant with numerous traditional applications such as anti-scarring, antiseptic, astringent, antifungal, and anti-tuberculosis. It is used against diarrhea, wounds, rheumatism, cough, gastrointestinal illnesses, hypertension, and haemorrhoids. Aim of the review: We...
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The protection of agricultural crops and the preservation of the organoleptic and health qualities of food products represent a major challenge for the agricultural and agro-food industries. Essential oils have received greater attention as alternatives to replace the control strategies based on pesticides against phytopathogenic bacteria and synth...
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Recently, a new coronavirus, named Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) has emerged in Wuhan, Hubei province, China. SARS-CoV-2 caused a global epidemic (COVID-19), which continues to kill thousands of people around the world today. With an exclusively interhuman transmission mode, in the absence of a vaccine, the spreading...
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Introduction: Arbutus unedo (Ericaceae) is a medicinal plant used traditionally to treat several diseases including oxidative stress related diseases and infectious diseases. However, the antimicrobial and antioxidant actions of A. unedo and its bioactive compounds have not been well studied. Therefore, the aim of this study was to evaluate the ant...
Article
Ethnopharmacological relevance: Origanum majorana L., is an aromatic and medicinal plant distributed in different parts of Mediterranean countries. This species is used in folk medicine to treat several diseases such allergies, hypertension, respiratory infections, diabetes, stomach pain, and intestinal antispasmodic. Aim of the review: This work r...
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Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused a global epidemic named COVID-19. This disease continues to kill thousands of people around the world. Physiopathological studies showed that different organs such as lungs, brain, kidneys, immune system, and heart are affected directly and/or indirectly...
Article
Ethnopharmacological relevance Pinus halepensis Mill., is a Mediterranean medicinal plant with numerous traditional applications such as anti-scarring, antiseptic, astringent, antifungal, and anti-tuberculosis. It is used against diarrhea, wounds, rheumatism, cough, gastrointestinal illnesses, hypertension, and hemorrhoids. Aim of the review We cr...
Chapter
Quorum sensing as intercellular signaling control of numerous multicellular behaviors, is implicated in microbial cell-cell coordination and involved in the development of multi-drug resistance. Targeting quorum sensing or quorum quenching is a promising strategy not only to decrease microbial resistance but also to treat microbial infections. Vari...
Chapter
Molecular communication in the rhizosphere plays an important role in plant-bacteria association. Quorum sensing or cell-cell microbial communication molecules coordinate several functions to establish and control this interaction, especially the interaction with the Plant growth-promoting rhizobacteria (PGPR) in the rhizosphere. Different chemical...
Article
Ethnopharmacological relevance: Thymus capitatus Hoffm. et Link. is an endemic medicinal plant to the Mediterranean region. It is used in folk medicine to treat various diseases including diabetes, flu, cough, flatulence, dermatitis, indigestion, respiratory disorders, asthma, rheumatic, diarrhea, and influenza. It is also used as antiseptic, analg...
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Origanum compactum Benth., is a Moroccan medicinal plant known by its local name as Zaatar . In Morocco, it has various traditional applications such as the use to treat diabetes, metabolic disorders, digestive, and respiratory problems. In this review, we critically highlighted current investigations on the ethnopharmacological studies, the phytoc...
Article
This study aims to determine the phytochemical compounds of Cistus ladaniferus subsp. ladanifer and Mentha suaveolens and the investigations of their antibacterial effects against phytopathogenic bacteria. The chemical composition of Cistus ladaniferus subsp. ladanifer essential oils (CLEO) and Mentha suaveolens essential oils (MSEO) was determined...
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Fresh olive oil mill wastewaters (OMW) were collected in northern Morocco from industrial mills operating with three extraction systems (two [C2] and three phase [C3] centrifugation decanters and super-pressure system [SP]) during the 2017 growing season. Physicochemical and microbiological characteristics of these effluents were examined. OMW phen...
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The present study reports the phenol and flavonoid contents of Cistus ladaniferus and Mentha suaveolens from Northern Morocco and the evaluation of their in vitro antioxidant and antimicrobial activities against gram positive, gram negative bacteria, and yeast. The results showed that the highest phenol and flavonoid content found in the aqueous ex...
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In order to discover new natural resources with biological properties, the chemical composition, the antioxidant, the antimicrobial activities and the potential use as food preservative of essential oils of Moroccan Achillea odorata subsp. pectinata (AOpEO) and Ruta montana (RMEO) were studied. Gas chromatography-mass spectrometry (GC-MS) analysis...
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In this study, water and various concentrations of methanol and ethanol in water were used as solvent in the extraction of aerial part of Ruta montana. The aims were to investigate the effects of solvents on the extraction of polyphenol from Ruta montana, from Taza region, and evaluate in vitro the antioxidant and antimicrobial activities against p...
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Published in: Moroccan Journal of Chemistry 7(1):211-223. Fresh olive oil mill wastewaters (OMW) were collected in northern Morocco from industrial mills operating with three extraction systems (dual [C2] and triple phase [C3] centrifugation decanters and super-pressure system [SP]) during the 2017 growing season. Physicochemical and microbiologic...
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An ethnopharmacological survey was carried out between December 2012 and May 2013 in eleven different locations dependent on the Guercif Province (NE of Morocco). The names of plants, their mode of preparation and administration, and their parts used have been inventoried for various local uses in traditional medicine. Our survey allowed us to iden...
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Although pharmacological industries have produced a number of new antibiotics, resistance of microorganisms to these drugs has increased. Some antibiotics have become almost obsolete because of drug resistance. In the course of our research program on medicinal plants, we investigated Haloxylon scoparium a species in Moroccan Sahara. In the present...

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Projects

Project (1)
Archived project
This project, having initially an ethnobotanical scope, was quite developed with the creation of the National Institute of Medicinal and Aromatic Plants (MAP), Mezraoua-Taounate, Sidi Mohamed Ben Abdellah University (USMBA), 2002-2015, becoming the National Agency of MAP (2015-) and no longer depends on the USMBA. The unifying project of the ex-Institute focused on the "of the plant to the finished product" chain.