Tanya Brown

Tanya Brown
University of Washington Seattle | UW · School of Aquatic and Fisheries Sciences

About

20
Publications
1,670
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
176
Citations
Citations since 2016
12 Research Items
134 Citations
20162017201820192020202120220510152025
20162017201820192020202120220510152025
20162017201820192020202120220510152025
20162017201820192020202120220510152025
Additional affiliations
August 2012 - present
Florida International University
Position
  • PhD Student

Publications

Publications (20)
Article
Full-text available
Coral bleaching events are increasing with such frequency and intensity that many of the world’s reef-building corals are in peril. Some corals appear to be more resilient after bleaching but the mechanisms underlying their ability to recover from bleaching and persist are not fully understood. We used shotgun proteomics to compare the proteomes of...
Article
Full-text available
Coral diseases have increased in frequency and intensity around the tropics worldwide. However, in many cases, little is known about their etiology. Montipora white syndrome (MWS) is a common disease affecting the coral Montipora capitata, a major reef builder in Hawai’i. Chronic Montipora white syndrome (cMWS) is a slow‐moving form of the disease...
Preprint
Full-text available
The microbiomes of tropical reef-building corals are actively studied using 16S rRNA gene amplicons to understand microbial roles in coral health, metabolism, and disease resistance. However, primers targeting bacterial and archaeal 16S rRNA genes may additionally amplify organelle rRNA genes from the coral, associated microbial eukaryotes, and enc...
Article
Full-text available
Examination of host-microbe interactions in early diverging metazoans, such as cnidarians, is of great interest from an evolutionary perspective to understand how host-microbial consortia have evolved. To address this problem, we analyzed whether the bacterial community associated with the cosmopolitan and model sea anemone Exaiptasia pallida shows...
Data
Location and sampling information within each site, including identification of Symbiodinium associated with anemones from natural populations (Grajales et al. 2016) and in captivity (this study)
Data
Prevalence and distribution of bacterial classes within the phylum Proteobacteria identified in the microbial community associated with the anemone Exaiptasia pallida across all population sites
Data
Number of observed and predicted (Chaos1) OTUs and alpha-diversity index per population site Standard deviations are presented along with the averages for both Chao1 and Shannon-Wiener Diversity Indices.
Data
Rarefaction curve generated using the mean number of OTUs for each sample location
Data
Frequency of V1–V3 16S rDNA OTUs shared among samples collected in the study Inset shows a close-up section of the main graph displaying the few OTUs shared from 79% to 40% of the analyzed samples.
Preprint
Full-text available
Examination of host-microbe interactions in basal metazoans, such as cnidarians is of great interest from an evolutionary perspective to understand how host-microbial consortia have evolved. To address this problem, we analyzed whether the bacterial community associated with the cosmopolitan and model sea anemone Exaiptasia pallida shows specific p...
Preprint
Full-text available
Examination of host-microbe interactions in basal metazoans, such as cnidarians is of great interest from an evolutionary perspective to understand how host-microbial consortia have evolved. To address this problem, we analyzed whether the bacterial community associated with the cosmopolitan and model sea anemone Exaiptasia pallida shows specific p...
Article
Journal of Antibiotics, official journal of the Japan Antibiotics Research Association, is a print and online publication that focuses on research on antibiotics and related types of medicinal substances
Article
Full-text available
Background: Staphylococcus aureus possesses exceptional virulence and a remarkable ability to adapt in the face of antibiotic therapy. We examined the in vitro evolution of S. aureus in response to escalating vancomycin exposure by evaluating bacterial killing and the progression of resistance. Methods: A hollow fiber infection model was utilize...
Article
Full-text available
Cnidarians, in general, are long-lived organisms and hence may repeatedly encounter common pathogens during their lifespans. It remains unknown whether these early diverging animals possess some type of immunological reaction that strengthens the defense response upon repeated infections, such as that described in more evolutionary derived organism...
Article
Full-text available
The impact of disease outbreaks on coral physiology represents an increasing concern for the fitness and resilience of reef ecosystems. Predicting the tolerance of corals to disease relies on an understanding of the coral immune response to pathogenic interactions. This study explored the transcriptional response of two putative immune genes (c3 an...
Data
Gel-banding profiles of 16S rDNA-PCR-DGGE of the bacterial communities associated with Acropora millepora coral nubbins at 24 h after bacterial inoculation. Alteromonas sp. (A); Vibrio coralliilyticus (V), and controls (C). Green arrows indicate bands most closely related to Endozoicomonas sp. and orange arrows to Oceanospirillum beijerinckii. (EPS...
Data
Photographs of Acropora millepora coral nubbins, from the second set of experiments, at 48 hours after inoculation with Vibrio coralliilyticus at different concentrations. A: 104 CFU/ml; B: 105 CFU/ml; C: 106 CFU/ml; and D: control. (EPS)
Article
Vancomycin-resistant enterococci (VRE) have emerged as an important nosocomial pathogen in medical centres worldwide. This study evaluated the impact of front-loading of linezolid on bacterial killing and suppression of resistance against VRE strains with defined genetic mutations. Time-killing experiments over 48 h assessed the concentration effec...
Article
Full-text available
Front loading is a strategy used to optimize the pharmacodynamic profile of an antibiotic through the administration of high doses early in therapy for a short duration. Our aims were to evaluate the impact of front loading of linezolid regimens on bacterial killing and suppression of resistance and on RNAIII, the effector molecule of the accessory...

Network

Cited By