Tanveer Hussain

Tanveer Hussain
Virtual University of Pakistan · Department of Molecular Biology

DVM, PhD

About

194
Publications
96,756
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1,017
Citations
Introduction
Tanveer Hussain PhD, is currently employed as Associate Professor and Heading the Department of Molecular Biology at Virtual University of Pakistan, Lahore-Pakistan. He is focused on different aspects of Genetics, Genomics, Production, Evolution and Conservation of Domestic and Wild Animals.
Additional affiliations
September 2014 - present
Virtual University of Pakistan
Position
  • Professor (Assistant)
Description
  • Teaching and Research
February 2014 - September 2014
University of Veterinary and Animal Sciences
Position
  • Professor (Assistant)
Description
  • Teaching and Research
November 2013 - December 2013
International Atomic Energy Agency (IAEA)
Position
  • Research Associate

Publications

Publications (194)
Preprint
Moringa oleifera is a famous tree species often known as horseradish tree or drumstick tree, belongs to the family Moringaceae. It is an evergreen and mineral rich plant that grows quickly, used in herbal medicine, agriculture, and the livestock sector. So far, only one draft genome assembly is available publicly for M. oleifera. Sparse availabilit...
Article
Coronavirus disease (COVID-19) pandemic has recently become a global health crisis. On the basis of this study the data reported from ten different countries on confirmed daily deaths caused by COVID-19. By fitting the linear regression models based on the data from ten countries to find the relationship between the new cases and deaths reported da...
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In this study, the prevalence of Avian orthoavulavirus-1 (AOAV-1) (also commonly known as Newcastle disease virus) was investigated in caged birds kept in bird markets in the Lahore district of Pakistan. A total of 354 swab samples were obtained from 14 different species of clinically healthy birds. The overall virus prevalence was 12.7% in 9 out o...
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Thermal stress is a persistent challenge to farm animals including cattle under tropical and subtropical climatic conditions and causes severe effects on the productivity of animals. In this study, complete coding sequences (CDS) of heat shock protein 70.1 (HSP70.1) gene sequenced in 45 unrelated animals were subjected to determine the genetic vari...
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End of the year 2019 marks an unprecedented outbreak of a pandemic named COVID-19 caused by the SARS-CoV-2. It was first discovered in China and later spread to the whole world, currently inflicting almost 200 countries. After China, few other countries have emerged as potential epicenters of this disease including the US, Italy, Spain and Pakistan...
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The COVID-19 pandemic is straining public health systems and the global economy, triggering unprecedented measures by governments around the globe. The adoption of a preventive measure is required to control the spread. This research explores the impact of influencing factors like COVID-19 knowledge, behavioral control, moral and subject norms, pre...
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This study was designed to investigate the impact of meteorological indicators (temperature, rainfall, and humidity) on total COVID-19 cases in Pakistan, its provinces, and administrative units from March 10, 2020, to August 25, 2020. The correlation analysis showed that COVID-19 cases and temperature showed a positive correlation. It implies that...
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Among the various species of livestock, the domestic yak (Bos grunniens) belongs to the class Bovidae and is specially adapted for survival at high altitudes under extreme climatic conditions. Yak is a very useful species due to the multiple products it provides, such as meat, hide, milk and other dairy products. Like other livestock species, domes...
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Cancer has emerged as a global health issue and become a one of major cause of deaths in 21 st century. The existing therapeutic approaches to prevent cancer are indeed beneficial but pose different risks to human health and now, tumor heterogeneity, non-specificity and untargeted delivery of anti-cancer drugs arise the problem of chemoresistance....
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The complete Cytchrome b gene and partial mtDNA control region were sequenced for the Pakistani domestic yak (Bos grunniens) within the Bovidae family. A total of 300 samples were genotyped using 27 bovine microsatellite markers from the Gilgit-Baltistan and Skardu regions of Pakistan. We identified a total of 35 mutations and 9 haplotypes based on...
Article
The complete Cytchrome b gene and partial mtDNA control region were sequenced for the Pakistani domestic yak (Bos grunniens) within the Bovidae family. A total of 300 samples were genotyped using 27 bovine microsatellite markers from the Gilgit-Baltistan and Skardu regions of Pakistan. We identified a total of 35 mutations and 9 haplotypes based on...
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The mitochondrial DNA sequences of DNA-D loops (mtDNA) from 105 individuals (11 Beetal goat Rajanpuri strains and 94 sequences extracted from GenBank) from 19 geographically and phenotypically defined domestic goat breeds in Pakistan were analysed in this experiment. In this study, we examined variability and molecular phylogeny of breeds. A total...
Article
The mitochondrial DNA sequences of DNA-D loops (mtDNA) from 105 individuals (11 Beetal goat Rajanpuri strains and 94 sequences extracted from GenBank) from 19 geographically and phenotypically defined domestic goat breeds in Pakistan were analysed in this experiment. In this study, we examined variability and molecular phylogeny of breeds. A total...
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Chlorpyrifos (ChF) is an organophosphate pesticide that is widely used in agricultural fields and indoor for controlling pests. Aquatic ecosystems are the recipients of various pesticide residues due to leaching spray drift and agricultural runoff and pose toxicity for aquatic organisms. Therefore, the current study was designed to investigate the...
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Keywords: Avian Coccidiosis; Risk Factors; Case-Control Flocks; Odds Ratio; Broiler and Layer Breeds; Management Factors; Seasonal Factors Commercial poultry sector is one of the most important segments of global trade and production. Coccidiosis, a worldwide disease of economic importance, significantly influences the production potential of this...
Preprint
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The traditional taxonomic approach for identification of species and their phylogenetic relationship is handicapped due to its limitations. The present study is carried out to evaluate the genetic identification and phylogenetic status of Corvus splendens (Common house crow) using mitochondrial cytochrome c oxidase subunit 1 (COX1). We amplified 69...
Article
The emergence of recombinant DNA (rDNA) technology occurred through the appropriate use of known procedures and tools in novel ways that resulted in broad applications for modifying and analyzing gene structure and organization of complex genomes. In the past centuries, the production of organisms having desirable traits was a mere imagination. Now...
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Scrapie is a fatal neurodegenerative disease caused by the accumulation of improperly folded forms of host-encoded cellular-prion protein (PrPc) in the central nervous system (CNS) and in some peripheral tissues in sheep and goats. Scrapie resistant/susceptibility have been associated with the presence of PRNP gene polymorphisms. We analyzed the po...
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Lactoferrin is one of the glycoproteins from the transferrin family which binds Fe3+ ion. Lactoferrin is found in mammalian milk but the camel milk has greater quantity of lactoferrinin compared with other livestock species. Lactoferrin strengthens the immune system by protecting the host cells against bacterial and viral infections and inflammatio...
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The genetic diversity of Pakistani dromedary camels is poorly documented. The present study evaluated the genetic variations of two well-known Pakistani camel breeds, Mareecha and Barela, that are well-adapted to the Cholistan desert climate. Camel can serve as a beneficial participant in the food supply chain by providing milk, meat and other food...
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p>La gacela india es oriunda de la zona silvestre del norte de Pendjab (Pakistán). De acuerdo a las categorías de la lista roja de la Unión Internacional de Conservación de la Naturaleza y los Recursos Naturales, constituye una especie en peligro. El entendimiento de la genética de la respuesta inmune en esta especie puede ser útil para diseñar efe...
Article
At the end of 2019, a novel infectious agent known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) originated from Hubei, China; from where it spread to other regions of the globe. In March 2020, World health organization (WHO) expressed fears that Pakistan might emerge as the next epicenter of corona virus infectious disease 2019...
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In current COVID-19 pandemic, when there is no specific antiviral treatment and vaccine is available yet, many nutritional supplements have caught the attention to manage the disease. Lactoferrin is one of a natural nutritional supplement found in the milk of livestock mammals and has immunomodulation property due to its iron withholding ability an...
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Background SARS-CoV-2 has the Spike glycoprotein (S) which is crucial in attachment with host receptor and cell entry leading to COVID-19 infection. The current study was conducted to explore drugs against Receptor Binding Domain (RBD) of SARS-CoV-2 using in silico pharmacophore modelling and virtual screening approach to combat COVID-19. Methods...
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Breast cancer is a commonly occurring malignancy and leading cause of cancer associated deaths in women globally. It is estimated that 1.7 million new cases (25% of all types of cancers) with 521,900 death in year 2012. There are multiple risk factors associated with breast cancer in women but breast density, genetic tendency, age and estrogen dysr...
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Interferons are secretory proteins induced in response to specific extracellular stimuli which stimulate intra-and intercellular networks for regulating innate and acquired immunity, resistance to viral infections, and normal and tumor cell survival and death. Type 1 interferons plays a major role in the CD8 T-cell response to viral infection. The...
Article
The world is facing a new pandemic called COVID-19. It started in December 2019 in Wuhan, China and in a few months it spread to almost every country of the world. Caused by a new streak of Coronavirus, it develops into an acute respiratory syndrome that becomes fatal particularly in the elderly. Since two similar Coronavirus epidemics happened in...
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During the present study total 40 samples (20♂ 20♀) were collected from different six wetlands of Punjab Pakistan. Among these samples total 17 samples (08% ♂, 09% ♀) were found infected with different gastro-intestinal parasites. The parasitic load was almost equally shared by the bird sampled from different sites (Chashma Barrage 37.50%; Taunsa B...
Preprint
Full-text available
End of the year 2019 marks an unprecedented outbreak of a pandemic named COVID-19 caused by the SARS-CoV-2. It was initiated in China and later spread to the whole world, currently inflicting almost 200 countries. After China, few other countries have emerged as potential epicenters of this disease including the US, Italy, Spain and Pakistan, as in...
Article
Full-text available
The present study was carried out to explore polymorphic patterns in the complete coding sequences of Toll-like receptor2 (TLR2) gene in Tharparkar cattle breed originating in Tharparkar district in Sindh province. Complete TLR2 gene [5'UTR 136bp, CDS 2355bp and 3'UTR 1316bp] was sequenced encoding 784 amino acids. Out of 14 variants observed in CD...
Article
COVID‐19 is a pandemic that began in China in December 2019. World health organization (WHO) has expressed fears that Pakistan might emerge as the next epicenter of this pandemic. We hypothesize that at present the Pakistani masses are not prepared to face any threat of a looming epidemic. The main aim of this study was to evaluate the basic knowle...
Article
The taxonomy of Alectoris chukar (A. chukar) has been a complex debate with different classifications and revisions suggested based on their morphology, geographical distribution and chromosome number. In Pakistan the Chukar partridge (A.chukar)), is an important member of Phasianidae family, however a scarce molecular data is reported that urged u...
Article
Sunlight filtered ultraviolet (UV) radiations are one of the most expected reason of skin malignancy. The intensity of photo-damage to skin, caused by the UV radiations varies with their type (UVA, UVB, and UVC). Human skin has developed a natural defense mechanism for protection against harmful UV radiations by producing vitamin D but climatic cha...
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Staphylococcus aureus is the leading cause of mastitis in dairy goats and is globally recognized as a significant mastitis-causing pathogen in dairy animals. Previous studies have established it as the causative agent of various human disorders, including food poisoning and Staphylococcal enterotoxins. Furthermore, poor sanitary conditions suit inf...
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Background It is becoming imperative to develop renewable fuels such as biodiesel which are sustainable and environmentally friendly. Exploiting non-edible oils is more necessary to reduce dependency of edible oils for biodiesel production. The current study investigated biodiesel production from non-edible Salvadora persica seed oil (SPSO) and cru...
Article
Despite intensive vaccination, endemicity of Avian paramyxoviruses-1 (APMV-1) is a significant problem in developing countries in Africa, Middle East, and Asia. Given the importance of APMV-1 in poultry and multiple non-poultry avian species, it is important to continue surveillance programs, routine monitoring and characterization of field isolate...
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Marker assisted selection (MAS) is a potential tool to genetically enhance the traits of economic importance in livestock production. One of the gateways to MAS is the identification of SNPs for the desired genes. The aim of the present study was to detect SNPs in myostatin (MSTN) gene which has a negative role in growth and skeletal muscle develop...
Article
Pakistani river buffalo is classified in five breeds out of which Kundi buffalo has been least documented. This study is designed to find single nucleotide polymorphisms (SNPs) in exonic and in-tronic regions of PRKAG3 (AMP-activated, Gamma3 non-catalytic subunit) gene in the Kundi buf-falo. The PRKAG3 gene of 95 animals each from Kundi and Nili-Ra...
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p>En Pakistán los recursos genéticos ovinos son abundantes, disponiéndose de varias diferentes castas extendidas en todo el país. No obstante, la diversidad molecular de las razas de ovejas es poco conocida en la región. Por ello, en el presente estudio se investigaron 16 marcadores microsatelitales de las razas indígenas Buchi y Hashtnagri, en las...
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Background and aim: Foot-and-mouth disease (FMD) has been occurring in Algeria since 2014, when an outbreak was announced in Setif, a district in the eastern region of the country. The problem was apparently resolved with the help of vaccination. However, in 2015, 2016, and 2018, FMD recurred. The veterinary authorities and media educated breeders...
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The study on evaluation of potential of the whole ATPase 6/8 region of the mitochondrial DNA as a molecular marker was conducted for determination of phylogeographic analysis of Labeo rohita. For detection of variations among the different weight groups from the same age class of this species samples were collected from the fish farming area in Pun...
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The earth ecosystem is facing instability in the present era due to unbridled devastating human activities across the globe. as a result we are losing species globally day by day. Indian Rock Python (Python molurus molurus) commonly recognized and pronounced as Indian Python, is considered as one among the list of larger size non-venomous snakes wh...
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In the present study, tobramycin stabilized silver nanoparticles (Tob-AgNPs) were effectively synthesized in an aqueous medium by well-organized one-pot technique and successfully employed for the ultra-fast catalytic reduction of 4-nitrophenol (4-NP) and 4-nitroaniline (4-NA). Moreover, the perfection was attained in percent reduction of toxic 4-N...
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Indigenous Aseel female chicken (120 birds) comprising of four varieties (Lakha, Mushki, Peshawari and Mianwali) was fed for 42-days experimental period on antibiotic and probiotic supplemented ration. The results showed that the female growth, weight gain, FCR and economics varied significantly for feed supplements as well as for chicken varieties...
Article
Full-text available
Staphylococcus aureus is the leading cause of mastitis in dairy goats and is globally recognized as a significant mastitis-causing pathogen in dairy animals. Previous studies have established it as the causative agent of various human disorders, including food poisoning and Staphylococcal enterotoxins. Furthermore, poor sanitary conditions suit inf...
Article
Full-text available
Genetic polymorphisms and diversity of BoLA-DRB3.2 are essential because of DRB3 gene’s function in innate immunity and its association with infectious diseases resistance or tolerance in cattle. The present study was aimed at assessing the level of genetic diversity of DRB3 in the exon 2 (BoLA-DRB3.2) region in African, American and Asian cattle b...
Article
This experimental design was developed to optimize the conventional and multiplex PCR reaction for detection of Staphylococcus aureus and Bacillus cereus from quail meat samples. Conventional PCR was optimized with annealing temperature 50°C, each primer concentrations of 10pmol, 200ng of DNA template and 10µl Qiagen master mix and 35 number of PCR...
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Background Necdin (NDN), a member of the melanoma antigen family showing imprinted pattern of expression, has been implicated as causing Prader-Willi symptoms, and known to participate in cellular growth, cellular migration and differentiation. The region where NDN is located has been associated to QTLs affecting reproduction and early growth in ca...
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Goats play a variety of roles all around the globe due to their capability to acclimatize different environmental conditions quite quickly since they have been regarded as one of the first sets of animals domesticated by the human. Even though domestic goats harbor precious genetic materials, research funding among developing countries is a major d...
Article
In 1993 miRNAs were discovered during a research on Caenorhabditis elegans conducted by Victor Ambros and Gary Ruvkun. The gene lin-4 that played important role in development in C. elgans was observed not encoding any protein but a very small RNA molecule of just 22 nucleotides. Main objective of this review is to highlight the significance of miR...
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Fowl adenovirus has been reported in many countries and is a contagious agent related with inclusion body hepatitis (IBH) and hydropericardium syndrome (HPS) in chickens worldwide. Identification of fowl adenovirus (FAdV) serotype is of most importance in epidemiological studies of disease outbreak and the adaptation of vaccine strategies. In spite...
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Zooarchaeological data indicates that the Near East and the Indus Valley were the centers of domestication and diffusion of modern day cattle. To better understand the origin and genetic diversity of native cattle breeds (Bos indicus) in Pakistan, partial sequencing of the mitochondrial gene cytochrome b (339 bp) was done in 136 individuals from 10...
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Full-text available
Genetic polymorphisms and diversity of BoLA-DRB3.2 are essential because of DRB3 gene's function in innate immunity and its association with infectious diseases resistance or tolerance in cattle. The present study was aimed at assessing the level of genetic diversity of DRB3 in the exon 2 (BoLA-DRB3.2) region in African, American and Asian cattle b...
Article
Full-text available
Twenty-nine avian avulavirus-1 viruses (AAvV-1s) from healthy domestic and wild ducks, geese and black swans collected in Pakistan between 2014-2017 have been pathotyped and genetically characterized. A phylogenetic analysis revealed that 21 of the isolates belonged to sub-genotype VIIi, whereas eight isolates were highly similar to vaccine-like vi...