Tamara Sofía Miranda-González

Tamara Sofía Miranda-González
Autonomous University of Chile | UA · Terapia Ocupacional

Magíster en Terapia Ocupacional Intervención Psicosocial

About

Additional affiliations
March 2011 - April 2016
University Santo Tomás (Chile)
Position
  • Directora de Escuela
March 2011 - June 2016
University Santo Tomás (Chile)
Position
  • Directora de Escuela

Projects

Project (1)
Project
In schizophrenia, neuroanatomical alterations are mainly represented by brain mass and volume reduction, accompanied by dilated ventricles. This is associated to prefrontal, subcortical and temporal dysfunction and implies alteration of various neurotransmission systems, especially in dopaminergic pathways. It has been established that brain mass reduction corresponds mostly to a decrease of grey matter at the cortex. This effect is greater in the temporal lobe. Morphological alterations of the temporal lobe, specifically the hippocampal formation, amygdala and parahippocampal gyrus are characterized by important volume reductions. Scheibel et al., have shown structural disorders in the hippocampus and entorhinal cortex which affect dopaminergic pathways relating to the basal ganglia. These basis account for psychomotor alterations in schizophrenia. Also, through the body and mind integration current, Reich and others comment an intrauterine origin for movement alterations describing characteristic patterns associated with head and neck motor block, tonic-clonic seizures, and low muscle hypotonia. Rood relates them to sensory integration, identifying proprioceptive and vestibular disorders; it is described that the origin of sensory integration affections are associated to problems in early development, referring to tonic muscle hypotonia, phasic patterns and the observed “S” posture (cervical kyphosis, lumbar hyperlordosis, retracted arms).