Takanobu Shioya

Takanobu Shioya
Akita University Hospital · Department of Physical Therapy

M.D., Ph.D.

About

183
Publications
12,460
Reads
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2,420
Citations
Additional affiliations
June 1984 - June 1986
University of Chicago
Position
  • PostDoc Position
September 1998 - present
Akita University
Position
  • Professor

Publications

Publications (183)
Article
Full-text available
In individuals who have experienced a stroke, the trunk remained relatively still during gait, but with significant asymmetries between the affected and unaffected sides. The purpose of this study was to clarify the factors involved in the improvement of trunk asymmetry during walking in patients with stroke. The study included 52 individuals with...
Article
Full-text available
[Purpose] Herein, we aimed to investigate the effects of bathing in a sodium chloride spring and an artificially carbonated spring on core body temperature and electroencephalograms, to assess whether the springs facilitate sleep. [Participants and Methods] This randomized, controlled, crossover study evaluated the effects of a sodium chloride spri...
Article
Objective: To develop an equation of the predicted amount of low-intensity physical activity (LPA) by analyzing clinical parameters in patients with chronic obstructive pulmonary disease (COPD). Methods: In this cross-sectional study, we analyzed the assessments of clinical parameters evaluated every 6 months from the start of pulmonary rehabili...
Article
Full-text available
Introduction Skeletal muscle dysfunction is one of the major extrapulmonary complications of chronic obstructive pulmonary disease (COPD). Some studies have reported a relationship between physical activity (PA) level and skeletal muscle quality assessed by echo‐intensity (EI) in healthy individuals but not in patients with COPD. Objectives The ai...
Article
Full-text available
Introduction: Current hypnotic agents have next-day residual effects. The new orexin antagonist, suvorexant, has little muscle relaxation effect on the physical and cognitive function in the following morning and daytime. In this study, the effects of suvorexant, zolpidem, ramelteon and placebo in elderly subjects were evaluated. Methods: Six me...
Article
Objectives: We aimed to identify the inspiratory muscle strength thresholds below which exercise capacity is compromised in men with chronic obstructive pulmonary disease (COPD). Methods: We measured the maximum static inspiratory mouth pressure (PImax) and the percentage of predicted values (%PImax) in 113 patients with COPD. Six-minute walk dista...
Article
Full-text available
Objectives: We aimed to identify the quadriceps muscle strength (QMS) thresholds below which exercise capacity is compromised in men with chronic obstructive pulmonary disease (COPD). Methods: We measured the quadriceps isometric maximum voluntary contraction (QMVC) and calculated the QMVC values normalized to weight (QMVC-BW), height squared (QMVC...
Article
Full-text available
[Purpose] The effect of physical activity on systemic inflammation remains unclear and might be negative in patients with chronic obstructive pulmonary disease (COPD) and lower weight. We investigated the amount of physical activity as the time spent in posture and movement and its association with systemic inflammation. [Participants and Methods]...
Article
Full-text available
Objective: To estimate the minimal clinically important difference (MCID) of quadriceps and inspiratory muscle strength after a home-based pulmonary rehabilitation program (PRP) in chronic obstructive pulmonary disease (COPD). Method: Eighty-five COPD patients were included. Quadriceps maximal voluntary contraction (QMVC) was measured. We measur...
Article
Introduction Bathing, especially with hot spring with various mineral compositions, is known to facilitate / improve sleep by warming the body. Artificial carbonated bathing (ACB) is known to keep the body warm too. Previous our study examined that ACB before sleep more specifically affected body temperature and sleep on healthy young subjects. In...
Article
Full-text available
Background: Ultrasound imaging has been widely used for imaging of the diaphragm thickness (Tdi) and thickening. Few studies assessed the Tdi using ultrasonography in patients with chronic obstructive pulmonary disease (COPD). We measured the Tdi and thickening in patients with COPD compared with healthy younger and healthy older adults to reveal...
Article
Purpose: The objective of this study was to investigate the impact of physical activity (PA) on mortality in the patients with COPD. Methods: In this retrospective study, 25 patients with COPD (Age 73 ± 7 years; FEV1 53.2 ± 27.2% pred) were participated. Their pulmonary function, exercise capacity, health-related QOL and PA were evaluated before st...
Article
Background: Abnormalities of spatiotemporal gait parameters are frequently observed in chronic obstructive pulmonary disease (COPD). However, associations of gait parameters with clinical outcomes and their implementation into clinical practice have not been established. Research question: To investigate gait abnormalities and their association...
Article
Full-text available
Background Individuals with COPD may experience ambulatory difficulty due to both effort intolerance arising from respiratory dysfunction and impaired balance control during walking. However, the trunk movement during walking has not been evaluated or adjusted for patients with COPD. The Lissajous index (LI) visually and numerically evaluates the l...
Poster
Full-text available
Background/Aim: Some studies have indicated that inspiratory muscle training (IMT) in chronic heart failure patients improves inspiratory muscle strength, exercise tolerance and quality of life. However the effect and safety of IMT in heart failure patients during the subacute phase has not been established. The aim of this study was to investigat...
Article
Full-text available
Background: Manually-assisted coughing and mechanical insufflation-exsufflation (MI-E) are commonly used in patients with Duchenne muscular dystrophy (DMD). Few studies have compared cough peak flow (CPF) with manually-assisted coughing to other methods, such as MI-E + manually-assisted coughing. In addition, few studies have reported the reliabil...
Article
Physical activity (PA) is defined as bodily movement produced by skeletal muscles with energy expenditure beyond resting levels. PA is closely related to reduced morbidity and mortality in chronic obstructive pulmonary disease (COPD). Self-report questionnaires are often subject to recall bias, correlating poorly with objectively qualified PA, and...
Article
Introduction We have been studying sleep facilitation of chloride spring and artificially carbonated spring (ACS). ACS are known to increase peripheral blood flow. We concluded that ACS caused great body temperature change and promoted sleep. On the other hand, ACS are also known to have an effect on the autonomic nervous system, but no one examine...
Article
Objectives: The purpose of this study was to confirm the intra-rater reliability and absolute reliability of Lissajous Index (LI) in evaluating the symmetry of trunk movement during gait in patients with stroke and to examine the relation between LI and body function in patients with stroke. Methods: Twenty-one healthy subjects (11 males and 10...
Article
Full-text available
[Purpose] The objective of this study was to investigate the validity of evaluation of posture and movement by a new tri-axial accelerometer (DynaPort MoveMonitor: DMM). [Subjects and Methods] Twenty-six healthy young university students cycled and the accuracy of the judgement of cycling by DMM was evaluated. The students also performed sitting, s...
Article
Purpose: The purpose of this study was to investigate cardiorespiratory responses and metabolism in acute stroke patients while in the following basic positions: supine, 30° head-up, sitting, sitting in a wheelchair, and standing. Method: A portable breath-by-breath system was used to determine oxygen uptake, carbon dioxide production, minute venti...
Poster
Full-text available
Inspiratory muscle strengh in patients with heart failure might be; 1] associated with exercise intolerance in youger patients 2] more closely related to lower-limb muscle strength and/or gait speed in order patients but older patients with inspiratory muscle weakness might reduce exercise tolerance
Article
Background/aim: To investigate the association between the number of circulating endothelial progenitor cells (EPCs) in non-squamous non-small cell lung cancer (NSCLC) and disease outcome, in combination chemotherapy with and without bevacizumab. Materials and methods: We retrospectively identified 25 non-squamous NSCLC cases, and divided them i...
Article
Full-text available
Introduction Next-day residual effects are a common problem with current hypnotic agents. The purpose of the present study was to evaluate the residual effects of the new agent - suvorexant that doesn’t have the muscle relaxation effect - on the physical and cognitive functions of healthy elderly people in the early morning and the day following dr...
Article
Recent advances in molecular biology research have helped to clarify the pathophysiology of cough. TRPV1 ion channels are biochemical sensors expressed in the airways that modulate activation of the sensory afferent neurons and induce the cough reflex. Inflammation of the upper respiratory tract secondary to infection activates the TRPV1 ion chan-n...
Article
Introduction: Mechanically assisted coughing (MAC) is an airway clearance method in which the thorax and/or the abdomen are compressed in synchronization with mechanical insufflation-exsufflation (MI-E). Aims: The purpose of this study was to examine the effects of four MAC procedures on pulmonary function in different conditions of patients with n...
Conference Paper
Background: Slow gait speed (GS) is well recognized in elderly COPD. However which parameter of gait contributes to GS has been uncertain. We aimed to investigate the determinants of GS among gait parameters, and the relationships between the gait parameters and clinical characteristics in elderly COPD. Methods: Twenty-three outpatients with COPD (...
Conference Paper
Aim: Diaphragm has important role during sleep to prevent hypoventilation especially Rapid Eye Movement (REM) stage. However, very few studies have been reported in regard to the relationship between nocturnal oxygenation and function of the diaphragm in COPD. Our aim was to investigate the relationship between nocturnal oxygen saturation and contr...
Conference Paper
Full-text available
Background: Little is known regarding the relationship between balance impairments and physical activity in COPD. We aimed to investigate the association between balance and physical activity measured by an accelerometer in elderly COPD. Materials and Methods: Twenty-two outpatients with COPD (age, 72±7 years; FEV1, 53±21%pred) and 13 age-matched h...
Conference Paper
Aim: The standard inspiratory muscle training (IMT) for COPD patients was low-intensity (30% maximal inspiratory mouth pressure: PImax) for 30 minutes until Langer (2015) showed that high-intensity (>50% of PImax) training of 30 breaths (3-5 minutes) was effective. We investigated the efficacy of moderate-intensity (40% of PImax) and short-duration...
Conference Paper
Objective: The aim of this study was to assess gait symmetry/asymmetry using a tri-axial accelerometer in elderly COPD. Methods: Gait symmetry/asymmetry wasevaluated in 16 elderly COPD (age; 71.3±9.2 years, FEV1; 58.4±20.1%pred), 17 healthy subjects(age; 63.4±2.0 years) and 16 stroke patients with hemiplegia(age; 54.9±12.3 years) as for control. Th...
Article
Full-text available
[Purpose] The purpose of this study was to validate a method for analyzing gait patterns determined by the center of mass (CoM) using an accelerometer. [Subjects and Methods] A tri-axial accelerometer was attached to the lower back of 11 healthy young males. Vertical and lateral CoM displacement were assessed using the accelerometer and a 3D motion...
Article
Full-text available
Background Little is known regarding the relationship between balance impairments and physical activity in COPD. There has been no study investigating the relationship between balance and objectively measured physical activity. Here we investigated the association between balance and physical activity measured by an activity monitor in elderly COPD...
Article
Physical activity (PA) is defined as any bodily movement produced by skeletal muscles that results in energy expenditure beyond resting energy expenditure. Physical activity is an important clinical parameter closely related to morbidity and mortality in COPD. A self-report questionnaire is often subject to recall bias, correlates only poorly with...
Article
The airways are innervated by a dual system of afferent sensory neurons and efferent motor neurons. Bronchopulmonary c-fibers play an essential role in regulating cough as they constitute an afferent pathway to the cough center in the medulla. One of the efferent pathways from the cough center runs from the phrenic nerve to the diaphragm and from t...
Conference Paper
Background: The Short Physical Performance Battery (SPPB) is commonly used in frail older people and in screening for sarcopenia. In general older population, the SPPB relates to functional exercise capacity and skeletal muscle function. However, it has been unclear whether SPPB score is associated with physical activity (PA) in chronic obstructive...
Article
With current hypnotic agents, next-day residual effects are a common problem. The purpose of the present study was to evaluate the residual effects of the commercially available hypnotics - zolpidem, triazolam, and rilmazafone - on the physical and cognitive functions of healthy elderly people in the early morning and the day following drug adminis...
Article
Pulmonary arteriovenous malformations (PAVMs) are direct communications between the pulmonary artery and vein through a thin-walled aneurysmal sac leading right to left shunt, thus causing paradoxical emboli or hypoxemia Overall, 30%, 10%, and 10% of patients with PAVMs have a history of stroke, brain abscess, and pulmonary or pleural hemorrhage, r...
Article
We evaluated the effects of low-intensity and home-based pulmonary rehabilitation (PR) on physical activity (PA) and the feedback provided by a pedometer in stable elderly patients with chronic obstructive pulmonary disease (COPD). We assessed PA using a newly developed triaxial accelerometer (A-MES™, Kumamoto, Japan), which measures the time spent...
Article
Full-text available
The purpose of this study was to investigate the relationship between dynamic hyperinflation and dyspnea and to clarify the characteristics of dyspnea during the 6-minute walk test (6MWT) in chronic obstructive pulmonary disease patients. Twenty-three subjects with stable moderate chronic obstructive pulmonary disease (age 73.8±5.8 years, all male)...
Article
Background and Purpose: The effectiveness of nutritional therapy in chronic obstructive pulmonary disease (COPD) has been shown in a recent Cochrane meta-analysis. However, little data has been reported concerning the effectiveness of a combination of nutritional therapy and exercise therapy in COPD. The purpose of this study was to verify the rela...
Article
Full-text available
[Purpose] The purpose of this study was to define the relationships between accelerations of the X-axis (mediolateral), Y-axis (vertical) and Z-axis (anteroposterior) measured by a triaxial accelerometry system and the weight load calculated by a foot pressure measurement system. [Subjects and Methods] The subjects were 17 healthy college students...
Article
Full-text available
Purpose: The purpose of this study was to evaluate the effect of the 6-minute Pegboard and Ring Test (6PBRT) on the respiratory and cardiac response and the motor function of the upper-limb in patients with chronic obstructive pulmonary disease (COPD). Methods: We evaluated the respiratory gas, the heart rate and the blood pressure during 6PBRT and...
Article
Full-text available
Purpose: We investigated the validity of a triaxial accelerometer system for measuring the time spent lying down, sitting, standing, walking, and operating a wheelchair by control subjects and stroke patients in a convalescence ward. Methods: Physical activities were measured using a new triaxial accelerometer system (A-MES; Activity Monitoring and...
Article
Full-text available
The purpose of this study was to quantify the walking time and frequency of postural changes in daily life in patients with chronic obstructive pulmonary disease (COPD) using a new triaxial accelerometer system. Twenty-six elderly patients with stable COPD (age 76.8 ± 6.2 years; percent forced expiratory volume in one second [%FEV1] 52.9% ± 26.3%)...
Article
Full-text available
The history of Pulmonary Rehabilitation (PR) dates back over decades and certain PR elements over centuries. The evidence of PR’s effectiveness has considerably strengthened and increased over the past forty years. During this time, the role and impact of PR has been firmly established and is now considered a key component in management of chronic...
Article
Full-text available
After the Great East Japan Earthquake, oxygen-dependent patients in areas experiencing power outages could not continue home oxygen therapy (HOT) without oxygen cylinders. The purpose of this study was to examine use of oxygen cylinders in areas experiencing power outages and the effects of HOT interruption on patients' health. Questionnaires were...
Article
Miura S, Satake M, Tamura Y, Ikeda M, Kawagoshi A, Sugawara K, Takahashi H, Homma M, Sakata S, Shioya T. Evaluation of walking time according to walking speed using a triaxial accelerometer system. Jpn J Compr Rehabil Sci 2013; 4: 73-79. Purpose: The primary purpose of this study was to quantify the walking time in daily life as slow and fast walki...
Article
抄録 〔目的〕2種類の加速度計により,座位での上肢活動レベルを判別した上で,上肢の1日の活動量を連続測定する方法の有効性を検討することを目的とした.〔対象〕実験1では健常学生10名を,実験2では健常学生19名を対象とした.〔方法〕実験1では,対象者に加速度計を装着した状態で,座位での活動の様子をビデオで記録した.次に加速度計で測定した時間とビデオで記録した時間から上肢の活動レベルを高,中及び低の3段階に判別した.実験2では,対象者の実際の日常生活での上肢活動量を2つの加速度計により測定し,1日の総座位時間,各活動レベルごとの上肢活動時間及び総座位時間に占める活動時間の割合を求めた.〔結果〕実験1の結果,加速度計およびビデオにより測定した時間はレベルの高い及び低い場合において非常に強い相関を示...
Article
[Purpose] The first purpose of this study was to evaluate the cough-induced energy expenditure (EE), and the second purpose of this study was to examine the difference in the cough-induced EE according to the frequency and the body position. [Subjects] Eighteen healthy students (age 22.2 ± 0.4) participated in this study. [Methods] Cough was induce...
Article
[Purpose] The purpose of this study was to evaluate the number of measurement days needed to measure physical activity time with respect to bodily posture and movement using a triaxial accelerometer, which detects tilt, that has recently been developed. [Methods] Physical activity time of 16 healthy young students with respect to bodily posture and...
Article
Background: One of the major pathophysiologies in advanced chronic obstructive pulmonary disease (COPD) has been attributed to systemic inflammation. Meta-analysis of the 2005 Cochrane Database concluded the effect of nutritional supplementation alone on stable COPD was insufficient to promote body weight gain or exercise capacity. The aim of this...
Article
Full-text available
Pulmonary arteriovenous malformations (PAVMs) are rarely encountered in clinical practice. The prevalence of PAVMs associated with hereditary hemorrhagic telangiectasia (HHT) has been estimated based on the rate in the family members of HHT patients, but the prevalence of PAVMs in the general population remains unknown. We retrospectively examined...
Article
Takahashi H, Sugawara K, Satake M, Shioya T, Kagaya H, Kawatani M. Effects of low-intensity exercise training (Chronic Obstructive Pulmonary Disease Sitting Calisthenics) in patients with stable Chronic Obstructive Pulmonary Disease. Jpn J Compr Rehabil Sci 2011; 2: 5-12. Objective: The purpose of this study was to investigate the effectiveness of...
Article
The purpose of this study was to evaluate the inhibitory effect of procaterol (procaterol hydrochloride, CAS 62929-91-3) on exercise dynamic lung hyperinflation during the 6-min walk test (6MWT) in stable chronic obstructive disease (COPD) patients. Fourteen patients with stable COPD who were referred to our clinic between July 2008 and October 200...
Article
Bone marrow-derived endothelial progenitor cells (EPCs) play an important role in angiogenesis and tumor growth. However, the clinical relevance of EPCs in non-small-cell lung cancer (NSCLC) remains unclear. Recently, some reports suggested that EPCs correlate with clinical behavior of cancer patients. We assessed the hypothesis that EPCs correlate...
Article
In the last 15 years, studies of transient receptor potential (TRP) channels have significantly extended our knowledge about the molecular basis of sensory function in pulmonary vagal afferents. In particular, TRPV1 and TRPA1 channels are unique cellular sensors for a wide range of inflammatory mediators and noxious irritants. These channels act as...
Article
Full-text available
Aim: The purpose of this study was to examine the validity of physical activity by a triaxial accelerometer which was developed in Japan recently. Subjects and Method :Ten healthy young students were studied in this study. They wore a triaxial accelerometer during their daily activities, and their physical activities (lying, sitting, standing, and...
Article
Study objectives: The first aim of this study was to investigate the effects of nutritional supplementation combined with low-intensity exercise on body components, exercise tolerance, and health-related quality of life (HRQOL) in malnourished patients with COPD. The second aim of this study was to examine the degree of systemic inflammation and t...
Article
Purpose: The purpose of this study was to evaluate the reliability and validity of IPAQ (International Physical Activity Questionnaire; Japanese Version) by comparing the physical activity measured by an activity monitor with IPAQ. Subjects and Methods: IPAQ was evaluated and re-evaluated for one week after the first evaluation of fifty-six healthy...