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42
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Introduction
Skills and Expertise
Publications
Publications (42)
Background
There are well documented associations between unmet social needs and undesirable health outcomes, but little data exist on the association between unmet social needs and stress in families of children with asthma.
Objectives
To document the relationship between unmet social needs and parental stress in a Canadian paediatric asthma clin...
Asthma exacerbations are a leading cause of emergency department (ED) visits in children. Outdoor exposures such as air pollutants and meteorological factors have been associated with risk of asthma exacerbations. We evaluated the association between ambient temperature, relative humidity, and air quality on pediatric asthma-related ED visits in Mo...
Background
Elevated markers of systemic and pulmonary inflammation are associated with failure to recover lung function following pulmonary exacerbations (PExs) in people with cystic fibrosis (pwCF). Our aim was to determine whether adjuvant oral prednisone treatment would improve recovery of forced expiratory volume in 1 second (ppFEV 1 ) in CF PE...
Background:
Asthma is a chronic respiratory condition that affects 10% of Canadian children and is often exacerbated by viral respiratory infections, prompting concerns about the severity of SARS-CoV-2 disease in children with asthma. We compared sociodemographic and clinical characteristics of children presenting to the emergency department and t...
Objectives:
We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new evidence and topic areas that were not previously addressed.
Design:
International consensus conference serie...
Objectives:
To summarize the evidence for the Second Pediatric Acute Lung Injury Consensus Conference-2 (PALICC-2) recommendations for assessment of outcomes among patients surviving pediatric acute respiratory distress syndrome (PARDS).
Data sources:
MEDLINE (Ovid), Embase (Elsevier), and CINAHL Complete (EBSCOhost).
Study selection:
We condu...
As functional respiratory impairment following COVID‐19 infection (COVID‐19) is increasingly reported in adult, data regarding children especially with pre‐existing chronic respiratory disease (PCRD) remain scarce. We retrospectively assessed clinical presentation, duration of symptoms related to COVID‐19 from paediatric patients with PCRD and comp...
BACKGROUND
Asthma is one of the most prevalent chronic diseases of childhood, affecting 1 in 10 children, and over 3 million Canadians. Asthma disproportionately affects children with lower socio-economic status (SES) who have higher prevalence of asthma, heavier symptom burdens, higher rates of ED visits, and hospital admissions. Controller medica...
Background:
Asthma is one of the most prevalent chronic diseases of childhood and disproportionately affects children with lower socioeconomic status. Controller medications such as inhaled corticosteroids significantly reduce asthma exacerbations and improve symptoms. However, a large proportion of children still have poor asthma control, in part...
Background: Asthma is the most common chronic pediatric disease. Despite existing tools to manage asthma, 40%-55% of children with asthma experience uncontrolled asthma. Serious games (SGs) represent a novel approach in promoting asthma education and self-management for children.
Objective: In this qualitative pilot study with an embedded quantita...
Background
Having a primary care provider and a continuous relationship may be important for asthma outcomes. In this study, we sought to determine the association between 1) having a usual provider of primary care (UPC) and asthma-related emergency department (ED) visits and hospitalization in Québec children with asthma and 2) UPC continuity of c...
BACKGROUND
Asthma is the most common chronic pediatric disease. Despite existing tools to manage asthma, 40-55% of children with asthma suffer from uncontrolled asthma. Serious games (SGs) represent a novel approach in promoting asthma education and self-management for children.
OBJECTIVE
In this qualitative study with an embedded quantitative des...
SARS-CoV-2 infection causing the novel coronavirus disease 2019 (COVID–19) has been responsible for more than 2.8 million deaths and nearly 125 million infections worldwide as of March 2021. In March 2020, the World Health Organization determined that the COVID–19 outbreak is a global pandemic. The urgency and magnitude of this pandemic demanded im...
Background:
To determine the lung function of children admitted to the intensive care unit (ICU) for a severe asthma exacerbation in the medium- to long-term following hospital discharge.
Methods:
We performed a retrospective chart review of children ≥6 years of age admitted to the ICU for a severe asthma exacerbation at a tertiary care center fro...
Background: International asthma guidelines recommend the monitoring of peak expiratory flow (PEF) as part of asthma self-management in children and adolescents who poorly perceive airflow obstruction, those with a history of severe exacerbations, or those who have difficulty controlling asthma. Measured with a peak flow meter, PEF represents a per...
BACKGROUND
International asthma guidelines recommend the monitoring of peak expiratory flow (PEF) as part of asthma self-management. Measured with a peak flow meter, it represents a person’s maximum speed of expiration and helps individuals to follow their disease evolution and ultimately to prevent asthma exacerbations. However, adherence to this...
Introduction
Children admitted to the intensive care unit (ICU) for asthma are at higher risk of future morbidity and mortality. Although Canada and the Unites States (US) may have difference population compositions, studies have documented that up to 34% of American children hospitalized for asthma require ICU admission, compared to 4.5% in Canada...
RATIONALE: There exists no validated index to assess pediatric asthma control in pharmacoepidemiologic studies.
OBJECTIVE: The objective of this study was to develop and validate a pharmacoepidemiologic pediatric asthma control index (PPACI) based on dispensed medications and health care utilization.
METHODS: Using a population-based birth cohort,...
Mobile health (mHealth) has tremendous potential to benefit patients, providers, and the entire healthcare system. Benefits for patients to adopt mHealth include more effective access to health providers, reduced costs of care, and better health control. For physicians and the healthcare system, reasons to embrace mHealth are enhanced health outcom...
Introduction
Preschoolers have the highest rate of emergency visits and hospitalisations for asthma exacerbations of all age groups, with most triggered by upper respiratory tract infections (URTIs) and occurring in the fall or winter. Vitamin D insufficiency is highly prevalent in Canadian preschoolers with recurrent asthma exacerbations, particul...
Rationale:
Although the methacholine challenge test is useful in the diagnosis of asthma, it is time-consuming in children. While protocols that quadruple methacholine concentrations are widely used in adults to shorten testing time, this has not been evaluated in children. Studies have not identified predictors associated with the safe use of a q...
Objectives:
While long-term sequelae of acute respiratory distress syndrome (ARDS) are well-documented in adults, few studies reported post-discharge respiratory complications in pediatric ARDS (PARDS) and none used the recent Pediatric Acute Lung Injury Consensus Conference (PALICC) diagnostic criteria. This study describes the respiratory sympto...
Poster presented at the General Meeting of the Global Alliance against Respiratory Diseases in Beijing.
Background: Worldwide, 6 people out of 10 have no access to treatment, or are not encouraged to follow it. Air pollution alone kills 7 million people yearly, reduces our life expectancy by 20 months, and costs 6% the gross world product. Devices...
Objectives: To compare the time to asthma-related readmission between children admitted to the intensive care unit (ICU) for asthma and those with a non-ICU hospitalization in the United States and to explore risk factors associated with readmission among children admitted in the ICU.
Methods: In this retrospective cohort study, we included childre...
Abstract Background New evidence supports the use of supplemental vitamin D in the prevention of exacerbation of asthma; however, the optimal posology to sufficiently raise serum levels while maximising adherence is unclear. The objective was to ascertain the efficacy of high-dose vitamin D3 in increasing serum vitamin D in preschoolers with asthma...
The Quebec Respiratory Health Network (RHN) Biobank is a multi-site infrastructure located in the province of Quebec (Canada) to collect, store, and supply high-quality human biological specimens for research on respiratory diseases. The sample types are diverse (plasma, serum, buffy coat, primary lung cells, lung parenchyma, bronchial biopsies, po...
Introduction
Childhood asthma is a significant public health problem in the United States, where more than 6 million children are affected by asthma. In 2011, a national survey showed that almost 611,000 Emergency Department visits and 200,000 hospital admissions annually among children are associated to asthma. There are no studies that have exhau...
Introduction
Parmi les enfants hospitalisés pour asthme aux, 6 à 12 % sont admis aux Unités de soins intensifs (USI). L’objectif était de comparer le délai de réadmission pour asthme chez des enfants hospitalisés antérieurement aux USI et ceux qui n’y étaient pas admis et d’identifier les facteurs de risque de réadmission en fonction du temps et de...
Objectives:
To compare the time to asthma-related readmissions between children with a previous ICU hospitalization for asthma and those with a non-ICU hospitalization and to explore predictors of time to readmission in children admitted to the ICU.
Design:
Retrospective cohort study using a pan-Canadian administrative inpatient database from Ap...
International guidelines recommend adding long-acting β2-agonists (LABA) to inhaled corticosteroids (ICS) as a step 3 or 4 strategy in children in whom ICS, with or without adjunct therapy, is ineffective in adequately controlling asthma [1–4]. Contrary to adults, the beneficial effects of ICS/LABA in children are limited to improving lung function...
Background:
Food insecurity, vitamin D deficiency and lower respiratory tract infections are highly prevalent conditions among Inuit children. However, the relationship between these conditions has not been examined in this population.
Objective:
The objective of this study was to examine the relationship between food insecurity and severe respi...
Food insecurity, vitamin D insufficiency and respiratory infections among Inuit children
Preschool children (ie, those aged 5 years or younger) with wheeze consume a disproportionately high amount of health-care resources compared with older children and adults with wheeze or asthma, representing a diagnostic challenge. Although several phenotype classifications have been described, none have been validated to identify individuals resp...