Swen Malte John- MD, PhD
- Professor (Full) at Osnabrück University
Swen Malte John
- MD, PhD
- Professor (Full) at Osnabrück University
About
712
Publications
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Introduction
Current institution
Additional affiliations
January 1984 - April 1984
May 1990 - present
Publications
Publications (712)
Background
Glove liners (GLs) are worn under impermeable gloves to prevent occlusion effects.
Objectives
To evaluate the acceptance and tolerability of cotton gloves (COT) and semipermeable Sympatex gloves (SYM) as GLs in patients with hand dermatoses.
Methods
In a prospective multicenter study, 210 patients with work‐related hand dermatoses were...
Background
Work‐related hand eczema (WRHE) is a prevalent skin condition associated with reduced health‐related quality of life (HRQoL), sleep disturbances or depression. While prior studies primarily explored emotional effects as part of HRQoL, emotions have been less studied separately.
Objectives
To evaluate the psychometric properties of the ‘...
Prolonged breastfeeding (BF), as opposed to artificial infant formula feeding (FF), has been shown to prevent the development of obesity later in life. The aim of our narrative review is to investigate the missing molecular link between postnatal protein overfeeding—often referred to as the “early protein hypothesis”—and the subsequent transcriptio...
Background
Smartphone apps are a growing field supporting the prevention of chronic diseases. The user experience (UX) is an important predictor of app use and should be considered in mobile health research. Long-term skin protection behavior is important for those with work-related skin diseases. However, altering health behavior is complex and re...
Hairdressers comprise a high-risk group for developing occupational hand eczema, for which a lifetime prevalence of 38.2% and a 1-year prevalence of 20.3% have been reported. Wet work and skin contact with irritants and allergens are the main contributing factors. Caused by work-related damage to the skin, the degradation of the epidermal barrier f...
Currently, no clinically relevant physiological markers of post-COVID exist, which stymies treatment development and rehabilitation efforts. Therefore, a monocentric cross-sectional study was conducted to characterize the long-term mental and physical health consequences of infection with SARS-COV-2. 156 participants were recruited as part of the v...
Allergic contact dermatitis is one of the most common occupational skin diseases. Due to the limited availability of commercial patch test preparations, patch testing patient’s own material (POM) is of great importance in the diagnosis of occupational contact dermatitis. In a research project (FB 317b) funded by the German Social Accident Insurance...
BACKGROUND
Smartphone apps are a growing field supporting the prevention of chronic diseases. The user experience (UX) is an important predictor of app use and should be considered in mobile health research. Long-term skin protection behavior is important for those with work-related skin diseases. However, altering health behavior is complex and re...
Background
Comfort gloves are used in the management of hand dermatoses.
Objectives
To compare the acceptance and tolerability of comfort gloves made of different materials in patients with hand dermatoses and their effects on skin lesions.
Methods
In a prospective multicenter study, 284 patients with hand dermatoses were invited to wear either a...
It is the purpose of this review to compare differences in postnatal epigenetic programming at the level of DNA and RNA methylation and later obesity risk between infants receiving artificial formula feeding (FF) in contrast to natural breastfeeding (BF). FF bears the risk of aberrant epigenetic programming at the level of DNA methylation and enhan...
Skin cancers constitute a serious public health issue in fair skinned populations globally, as they account for a substantial proportion of all reported occupational diseases. The number of workers diagnosed with skin cancer has continuously grown in recent times. Solar ultraviolet radiation (UVR) is the leading cause of non-melanoma skin cancer (N...
Introduction
The more we know about the prevalence of skin cancer and the work environment, the more we can act for preventive and corrective measures. This study works on a solution for risk assessment of UVR exposure in outdoor workers of the Lisbon Municipality (Portugal). The solution will have a digital component for the validation and integra...
In fair-skinned populations worldwide, skin cancer is a serious public health threat. A significant percentage of all reported occupational diseases fall back on skin cancer. Over the past few decades, there has been a rise in the frequency of skin cancer diagnoses among outdoor workers. The main cause of non-melanoma skin cancer is solar ultraviol...
Patch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of Type IV patch test (PT) allergens in Europe, however, is currently scarce. This severely compromises adequate diagnostics of contact allergy, leading to serious consequences for the affected patients. Against this background, the European Soci...
The diagnosis of eczema (‘dermatitis’) is mostly clinical and depends on the clinical history and exploratory objective findings (primary lesions, patterns). Contact dermatitis remains as an important condition in the group of eczematous disorders, with important socioeconomic and occupational relevance. Although irritant and allergic contact derma...
Zusammenfassung
Hintergrund und Ziele
Beschäftigte im Freien haben ein erhöhtes Risiko, an Nicht‐Melanom‐Hautkrebs zu erkranken. Ziel dieser Studie war es, den Mangel an validierten deutschsprachigen Messinstrumenten für das Sonnenschutzverhalten und ‐wissen von Außenbeschäftigten durch das Zusammenstellen und Validieren von zwei Fragebögen zu beh...
The term prevention includes measures that are used to avoid illnesses or damage to health as well as to reduce the risk of illness or to delay its occurrence. Preventive measures can be classified based on various criteria: temporal differentiation (primary, secondary, and tertiary prevention), context (behavioral and relational prevention), and r...
Background and objectives
Outdoor workers are at increased risk of developing non‐melanoma skin cancer. We aimed to address the lack of validated German‐language measurement instruments for outdoor workers’ sun safety behavior and knowledge by compiling and validating two questionnaires.
Participants and methods
By expert consensus, items for the...
b>Hintergrund: Das chronische Handekzem (CHE) ist eine sehr häufige Hauterkrankung in der europäischen Bevölkerung. Es verursacht Juckreiz und Schmerzen und beeinträchtigt in schwereren Fällen die Funktion der Hände bei der Arbeit und im Privatleben erheblich. Ziele: Perspektiven von Menschen zu erforschen, die mit CHE leben, und deren Probleme, Wü...
Healthcare workers (HCWs) are considered a high‐risk group for developing hand eczema (HE), mainly owing to wet work and contact with allergens at work. To meta‐analyse the prevalence and incidence of HE in HCWs, as well as mapping the prevalence of atopic dermatitis (AD) and HE severity in HCWs. A systematic review and meta‐analysis was performed...
Tertiary Individual Prevention is an interprofessional inpatient rehabilitation programme offered to workers affected by work-related skin diseases. Health educational interventions aiming at changing skin protection behaviour are a pivotal component of the programme. This paper aims at characterizing the content of the educational interventions of...
Background
Occupational contact dermatitis (OCD) is a prevalent, often chronic disease that poses a risk for job loss and decreased quality of life. In Germany, a multi‐step prevention programme emphasising early detection and highly specialised multidisciplinary treatment has been implemented with great success.
Objectives
To examine the effectiv...
Background
Due to limited availability of commercial test preparations, patch testing patient's own material (POM) is of great importance to diagnose occupational allergic contact dermatitis.
Objectives
To assess the quality of performance and documentation of patch testing with POM in patients with suspected occupational skin diseases (OSD) in Ge...
Due to their professional activities, outdoor workers are exposed to an increased risk of developing occupational skin cancer caused by solar ultraviolet (UV) radiation as defined by occupational disease (OD) number 5103. Since the amendment to the Occupational Diseases Ordinance (“Berufskrankheitenverordnung”, BKV) in 2015, squamous cell carcinoma...
Background
A programme based on health education has been developed to prevent foot dermatoses (FD) in patients with work‐related skin diseases (WRSD).
Objective
To evaluate the effectiveness of the programme in a prospective cohort study (OCCUPES).
Methods
Six and 12 months after completing the programme, follow‐up questionnaires were sent to 23...
Zusammenfassung
Aktinische Keratosen (AK) sind häufige Hautveränderungen bei hellhäutigen Menschen mit dem Potenzial, in ein kutanes Plattenepithelkarzinom (PEK) überzugehen. Beide Erkrankungen können mit erheblicher Morbidität verbunden sein und stellen eine große Krankheitslast insbesondere in der älteren Bevölkerung dar. Um einen evidenzbasierte...
Zusammenfassung
Aktinische Keratosen (AK) sind häufige Hautveränderungen bei hellhäutigen Menschen mit dem Potenzial, in ein kutanes Plattenepithelkarzinom (PEK) überzugehen. Beide Erkrankungen können mit erheblicher Morbidität verbunden sein und stellen eine große Krankheitslast insbesondere in der älteren Bevölkerung dar. Um eine evidenzbasierte...
Actinic keratosis (AK) are common lesions in light‐skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence‐based framework for clinical decision making, the...
Actinic keratosis (AK) are common lesions in light‐skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence‐based framework for clinical decision making, the...
Zusammenfassung
Bereits seit vielen Jahren werden textile Handschuhe als Komfort- oder Unterziehhandschuhe in der Prävention von Berufsdermatosen eingesetzt, z. B. zur Abmilderung von Okklusionseffekten beim Tragen flüssigkeitsdichter Schutzhandschuhe oder zur Unterstützung der Externatherapie. In den letzten Jahren wurden Handschuhe aus semipermea...
Background
Occupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.
Objectives
To determine the prevalence of previously diagnosed AD among young workers with recognized OCD and assess its impact on OCD prognosis.
Methods
A retrospective cohort study. A questionnaire was sent t...
The consensus-based guideline "Diagnosis, prevention, and treatment of hand eczema (HE)" provides concrete instructions and recommendations for diagnosis, prevention, and therapy of HE based on an evidence- and consensus-based approach. The guideline was created based on the German guideline "Management von Handekzemen" from 2009 and the current gu...
Zusammenfassung
Die S2k‐Leitlinie „Diagnostik, Prävention und Therapie des Handekzems (HE)“ gibt auf der Grundlage eines evidenz‐ und konsensbasierten Ansatzes konkrete Handlungsanweisungen und Empfehlungen für die Diagnostik, Prävention und Therapie des HE. Die Leitlinie wurde auf der Grundlage der deutschen Leitlinie „Management von Handekzemen“...
Background
Programmes for prevention of hand dermatoses in patients with work‐related skin diseases (WRSD) are well established. Similar interventions for foot dermatoses (FD) are widely missing.
Objective
To evaluate the effectiveness of a programme for prevention of FD based on health education in patients with WRSD while investigating the impac...
Teledermatology has become very popular, and not only due to the SARS-CoV-2 pandemic. Patients with occupational skin diseases (OSDs) could also benefit from teledermatology services as part of their follow-up care, but the opportunities and challenges for patients and dermatologists, especially regarding quality and satisfaction, need exploration....
Since January 1, 2021, recognition of occupational hand eczema as an occupational disease (OD) No. 5101 has been made significantly easier by eliminating the obligation to cease and desist work in the eczema-eliciting job. As a result of this change in OD law, an occupational disease can now also be recognized if the patient continues the (eczema-e...
Background
Occupational skin diseases (OSD) in the form of hand eczema (HE) are a common work-related disease. Illness perceptions as presented in Leventhal’s Common-Sense Model (CSM) are important for patients’ self-management of diseases. Understanding these illness perceptions is essential for patient communicating. No quantitative or qualitativ...
Zusammenfassung
Hintergrund
Berufsbedingte Hauterkrankungen treten in vielen Berufen auf. Häufig handelt es sich um irritative und/oder allergische Handekzeme. Zu den häufigsten betroffenen Berufsgruppen zählen z. B. Pflegekräfte und Metallarbeiter*innen. Hinsichtlich soziodemografischer Merkmale (Alter, Berufe, Geschlecht) ist das Patientenklient...
Background
Chronic hand eczema (CHE) is a very common skin disease among the European population. It causes itch and pain and, in more severe cases, seriously impairs hand functioning at work and in private life.
Objectives
To explore perspectives of people with lived experience on CHE‐related problems, wishes and goals.
Methods
Following a quali...
Objectives: To investigate the illness perceptions of patients with occupational skin diseases (OSDs). Design: Cross-sectional study. Setting: Specialised healthcare centre for inpatient and outpatient individual prevention in occupational dermatology in Germany. Participants: A total of 248 patients with hand eczema (55.2% female; average age: 48....
Purpose of Review
This study aims to provide an overview on current knowledge on occupational allergic diseases in hairdressers and up-to-date perspectives of prevention.
Recent Findings
Hand eczema (dermatitis) is common in hairdressers, often caused by contact allergy to one or multiple small molecules (haptens) used, e.g., for dyeing, bleaching...
Background
Semipermeable membranes might be suitable for glove liners or comfort gloves in individuals with irritant contact dermatitis (ICD).
Objectives
To evaluate the effects of different glove materials on inflammation and epidermal barrier impairment after experimental skin irritation.
Methods
Nine test areas on the volar forearms of 24 heal...
Introduction
The rising incidence of skin cancer over the years has made it a significant public and occupational health issue. However, skin cancer is highly preventable, mainly through reduced exposure to solar ultraviolet radiation (UVR), which can be achieved by a variety of individual and collective protective measures and interventions. The r...
Skin cancers constitute a serious public health issue in fair skinned populations globally, as they account for a substantial proportion of all reported occupational diseases, and the number of workers diagnosed with skin cancer has continuously grown in recent times. Solar ultraviolet radiation (UVR) is the most important occupational carcinogenic...
Introduction
Hairdressers are at increased risk for hand eczema (HE) due to frequent skin contact with irritants and allergens in the workplace. Individuals with (a history of) atopic dermatitis are more susceptible to develop occupational HE. This study aims to review the current prevalence and incidence of HE in hairdressers, as well as the patte...
Introduction
Hairdressers are at increased risk of adverse health effects due to exposure to hazardous chemicals released from hair care products during hairdressing activities. Safety assessments of hair products consider only consumer exposure, however exposure for professional hairdressers might be substantially higher. In this study we aimed to...
This systematic review, conducted according to the PRISMA guidelines, focuses on genotoxicity of oxidative hair dye precursors. The search for original papers published from 2000 to 2021 was performed in Medline, Web of Science, Cochrane registry, Scientific Committee on Consumer Safety of the European Commission and German MAK Commission opinions....
Solar ultraviolet radiation (UVR) is the most significant occupational carcinogenic exposure in terms of the number of workers exposed (i.e., outdoor workers). Consequently, solar UVR-induced skin cancers are among the most common forms of occupational malignancies that are potentially expected globally. This systematic review is registered in PROS...
Skin cancer has become a substantial matter of public health and in the workplace, accounting for a significant share of all reported occupational diseases. The most important external factor in the development of skin cancer is exposure to solar ultraviolet radiation. Outdoor workers have already been identified as a high-risk category. The need f...
Friseurinnen und Friseure sind deutlich häufiger einem breiten Spektrum haarkosmetischer Produkte ausgesetzt als Verbraucherinnen und Verbraucher. Die Chemikalien, mit denen Friseurinnen und Friseure täglich arbeiten, können ihre Gesundheit stark beeinträchtigen. In einem von der Europäischen Kommission geförderten Projekt wurde untersucht, wie der...
Background
Hand eczema (HE) is a common skin disease characterized by itch, pain and visible skin changes such as fissures, erythema and vesicles. It is not yet clear which outcome domains are most important for patients. The Hand Eczema Core Outcome Set (HECOS) initiative is developing a consented set of core domains and suitable measurement instr...
Purpose of Review
This review evaluates cow milk’s impact on breast carcinogenesis by linking recent epidemiological evidence and new insights into the molecular signaling of milk and its constituents in breast cancer (BCa) pathogenesis.
Recent Findings
Recent prospective cohort studies support the association between cow’s milk consumption and th...
Nickel und Kobalt zählen in der Allgemeinbevölkerung seit Jahrzehnten zu den am häufigsten sensibilisierenden Kontaktallergenen. Im Rahmen aktueller Arbeiten wurde eine allergologisch relevante Nickel- und Kobaltliberation sowohl aus Friseur- als auch aus Kosmetikwerkzeugen nachgewiesen. In der täglichen Praxis lässt sich eine Freisetzung dieser Me...
A substantial proportion of all reported occupational illnesses are constituted by skin cancer, making this disease a serious public health issue. Solar ultra-violet radiation (UVR) exposure is the most significant external factor in the development of skin cancer, for which the broad occupational category of outdoor workers has already been identi...
Background
Various products are available for lightening hair. There are no data on which applications are actually used in hairdressing, impeding proper estimation of actual exposure and necessary preventive measures.
Objectives
To assess information about availability, usage and formulation of lightening preparations in the German hairdressing t...
https://doi.org/10.1093/bjd/ljac053
Cobalt – whose clinical evaluation is performed with CoCl2 (1%) in petrolatum – ranks among the most common contact allergens, according to current data by the German Information Network of Departments of Dermatology.¹ In an experimental study reported in this issue of the BJD, Midander et al. show that cobalt na...
Background
The burden of occupational hand eczema in hairdressers is high, and (partly strong) allergens abound in the hair cosmetic products they use.
Objectives
To systematically review published evidence concerning contact allergy to an indicative list of active ingredients of hair cosmetics, namely, p‐phenylenediamine (PPD), toluene‐2,5‐diamin...
Introduction
Healthcare workers (HCWs) constitute a high-risk group for developing occupational hand eczema (HE). The present systematic review and meta-analysis will compile and appraise evidence regarding prevalence and incidence of HE in HCWs.
Methods and analysis
Systematic searches will be performed in three electronic literature databases (P...
Berufsdermatosen i. S. der Berufskrankheit (BK) Nr. 5101 stellten in den Jahren vor der COVID-19-Pandemie regelmäßig den Hauptanteil aller beruflichen Erkrankungen dar. Sie traten entsprechend häufig in der gutachterlichen Praxis auf; dies ist zukünftig umso mehr zu erwarten, nachdem durch die BK-Rechtsreform von Januar 2021 mit dem Wegfall des Unt...
Background
Occupational hand eczema (HE) is common among healthcare workers (HCWs) and has—in some regions of the world—increased during the COVID‐19 pandemic due to related hygiene measures.
Objectives
To evaluate the efficacy of an intervention for HE prevention in HCWs during the pandemic.
Methods
A prospective, controlled, unblinded intervent...
Objectives:
To review recent epidemiological studies investigating carcinogenic or reprotoxic effects among hairdressers who seem to be at greater risk for systemic adverse effects of chemicals released from hair care products than consumers.
Methods:
A systematic review according to the PRISMA-P guidelines was performed and included studies pub...
Objectives
Digital interventions are increasingly used to support behaviour change. In the prevention of chronic work-related skin diseases, the sustainable implementation of appropriate skin protection behaviour following tertiary individual prevention is important. However, there exists no intervention to support the maintenance of these behaviou...
The safety assessment of cosmetics considers the exposure of a ‘common consumer’, not the occupational exposure of hairdressers. This review aims to compile and appraise evidence regarding the skin toxicity of cysteamine hydrochloride (cysteamine HCl; CAS no. 156-57-0), polyvinylpyrrolidone (PVP; CAS no. 9003-39-8), PVP copolymers (CAS no. 28211-18...
Im Zuge von COVID-19-assoziierten Hygienemaßnahmen wurde ein vermehrtes Auftreten von beruflich bedingten Handekzemen und Gesichtsdermatosen verzeichnet. Da in der näheren Zukunft nicht mit einem Rückgang der Hygienemaßnahmen zu rechnen ist, müssen umso mehr adäquate, situationsangepasste Präventionsmaßnahmen etabliert werden.
Background
Healthcare workers (HCWs) are at high risk of developing hand eczema (HE). This can be exacerbated by hygiene measures related to the coronavirus disease (COVID-19). Using mild skin cleansers and emollients or moisturizers is central in the prevention of HE—especially with increased COVID-19 hygiene regimes.
Aims
This study aimed to ass...
Background
Semipermeable gloves might be an alternative to cotton gloves in management of hand dermatoses.
Objectives
To compare acceptance and tolerability of gloves made of cotton or a semipermeable Sympatex membrane in patients with hand dermatoses and their effect on skin lesions when worn overnight.
Methods
A total of 199 patients with work‐...
Background
Increased hand hygiene measures during the COVID‐19 pandemic have led to an increased quantum of hand eczema (HE).
Objectives
To examine the effects of varying washing frequencies using current mild cleansing agents—alongside with the effect of a rehydrating cream—on the epidermal barrier function and inflammatory processes of the strat...
Zusammenfassung
Hintergrund
In Außenberufen beschäftigte Personen (z. B. Straßenbauer*innen) sind solarer UV-Strahlung in hohem Maße ausgesetzt. Um die Entstehung von berufsbedingtem Hautkrebs zu verhindern, sind Präventionsmaßnahmen unerlässlich.
Ziel
Das Ziel der Projekte „ForMulA UV 1.0 & 2.0“ war die Entwicklung und Pilotierung sowie die form...
In Germany, a stepwise multidisciplinary approach has been established to prevent occupational skin diseases (OSDs), primarily occupational contact dermatitis. This review aims to perform a systematic evaluation of the short‐ and long‐term effects of the German secondary and tertiary individual prevention programmes (SIP and TIP, respectively) for...
Background
Relevant nickel and cobalt release from hairdressing tools has recently been evidenced. Comparable data are not available for tools used in beauty salons.
Objectives
Screening of beauty tools for nickel and cobalt release.
Methods/Materials
Three hundred eight beauty tools were tested in seven beauty salons located in two North‐German...
